TCONS_00034959-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00034959-protein
Unique NameTCONS_00034959-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length500

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00034959-protein ID=TCONS_00034959-protein|Name=TCONS_00034959-protein|organism=Clytia hemisphaerica|type=polypeptide|length=500bp
VFLEFSLKFRVLLQVGIESRKILLKMWIRFLSIFFILIRFGSGMITEKEI
TRIYREALKNYEKRSVPIRDGKPVEVRMRISINNMVPRKKSPMHFHMDFY
VTLFWEDYRLAFNHTENYTNHKNNVDYLPYDVHLSEKIWTPNLYLVESKF
GWKNDVPQPNVMIYLYPNGTVGFNFRLNVGLYCAMQMRYFPFDKQHCQMT
IETYSYNSGYVKLKWSIVEQVKKLHITDFAKVEIHKTEKPDVDYGHIGKW
DQLILKLTFYRNSNLYLVRDFFPCFLIVSLSWINFWVTHRSTPARVALGI
TTVLTIVTMTNSVRSQAPSSGLFRCIDVYMLCCNLFVFAALGEAALVGMT
APSEKHANEKEKDEKEKAKEKTNKDKKKAQKVNDNPLSFDNPVFKRTESV
VNNGNGIHSNHQNGDMTTKTKLRTRSIFRNSKNAPEKEAKPKKTFNPLLT
NIKKVGPVYFYTQDVHIVDKISRVLFPVLFILFNVLFFFVIHMVNEDTTI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_020352XLOC_020352Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00034959TCONS_00034959Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006028GABAA/Glycine_rcpt
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 355..385
NoneNo IPR availableGENE3D1.20.58.390coord: 268..499
e-value: 3.8E-36
score: 123.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 353..383
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 480..492
score: 20.61
coord: 183..197
score: 47.93
coord: 137..148
score: 34.84
coord: 96..112
score: 30.18
IPR006028Gamma-aminobutyric acid A receptor/Glycine receptor alphaPRINTSPR00253GABAARECEPTRcoord: 266..286
score: 40.46
coord: 292..313
score: 52.74
coord: 326..347
score: 48.23
coord: 471..491
score: 39.95
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 51..239
e-value: 4.9E-37
score: 127.4
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 41..267
e-value: 2.3E-41
score: 141.1
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 50..262
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 272..488
e-value: 4.2E-21
score: 76.0
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 266..493
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 183..197

Blast
BLAST of TCONS_00034959-protein vs. Swiss-Prot (Human)
Match: GBRR3 (Gamma-aminobutyric acid receptor subunit rho-3 OS=Homo sapiens GN=GABRR3 PE=3 SV=2)

HSP 1 Score: 189.119 bits (479), Expect = 2.474e-54
Identity = 116/428 (27.10%), Postives = 210/428 (49.07%), Query Frame = 0
Query:   67 PIRDGKPVEVRMRISINNMVPRKKSPMHFHMDFYVTLFWEDYRLAFNHTENYTNHKNNVDYLPYDVHLSEKIWTPNLYLVESKFGWKNDVPQPNVMIYLYPNGTVGFNFRLNVGLYCAMQMRYFPFDKQHCQMTIETYSYNSGYVKLKWS----IVEQVKKLHITDFAKVEIHKTEKPDVDYGHIGKWDQLILKLTFYRNSNLYLVRDFFPCFLIVSLSWINFWVTHRSTPARVALGITTVLTIVTMTNSVRSQAPSSGLFRCIDVYMLCCNLFVFAALGEAALVGMTAPSEKHANEKEKDEKEKAKEKTNKDKKKAQKVNDNPLSFDNPVFKRTESVVNNGNGIHSNHQNGDMTTKTKLRTRSIFRNSKNAPEKEAKPKKTFNPLLTNIKKVGPVYFYTQDVHIVDKISRVLFPVLFILFNVLFFFV 490
            P   G PV V + + + ++    ++ M F M FY+  +W+D RL+F  T N +        + +D  L+ KIW P+++ V SK  + +D    N+M+ ++P+G V  + R+ V   C M    FP D Q+C + +E+Y+YN   + L W      +   + + ++ F  +E          Y   G +++L +     R+   ++++ +FP  L+V LSW++FW+  R+ PARV+LGITTVLT+ T+  +V +  P     + +DVY+   +LFVF ++ E A V      E+    K+  +  K     N D  +A       ++FD                 H +  + D T+ +      + R S  +P  ++   K    L  ++ ++       ++ H++D  SR+LFP+++ILFN+ ++ V
Sbjct:   76 PGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKS--------MTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFF-IEDFSASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEE---RKQFKKTGKISRMYNIDAVQA-------MAFD--------------GCYHDSEIDMDQTSLSLNSEDFMRRKSICSPSTDSSRIKRRKSLGGHVGRI-----ILENNHVIDTYSRILFPIVYILFNLFYWGV 465          
The following BLAST results are available for this feature:
BLAST of TCONS_00034959-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GBRR32.474e-5427.10Gamma-aminobutyric acid receptor subunit rho-3 OS=... [more]
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