TCONS_00025387-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00025387-protein
Unique NameTCONS_00025387-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length348

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00025387-protein ID=TCONS_00025387-protein|Name=TCONS_00025387-protein|organism=Clytia hemisphaerica|type=polypeptide|length=348bp
MIRNVAFVLGRQSKIFIRGAHRAANSKQSRFLTHKSVQLPILTAFGSYIV
YRSTQANTVDAAEDHQNESKWTLYQYATCPFCCKVRSFLDYYGVDYEIVE
VNPVSRKEIKFSEYRKVPFLTSKEHQLNGSSLICSVLKTQLITESEVSKI
LTYYPILENEDGKKKSFDYQNIYNVMYETGIGKEAHDKVRDEMKWRRWVD
EVFVHTLSPNIYRTWGESLQAMEYITKVGNFSDFERTLIYYSGAVAMYLI
GKRLKHRHHLRNEVRESLYEETYRWLKAVGKNPYQGGDQPNMADLNMYGV
LSAIEGYDAFSDLLQNTNIGPWYQRMKTKVKNKDGIQEVQRLKAMKLN
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_014256XLOC_014256Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00025387TCONS_00025387Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR004045Glutathione_S-Trfase_N
IPR034334PGES2
IPR011767GLR_AS
IPR002109Glutaredoxin
IPR034335PGES2_C
IPR010987Glutathione-S-Trfase_C-like
IPR012336Thioredoxin-like_fold
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0050220prostaglandin-E synthase activity
GO:0009055electron carrier activity
GO:0015035protein disulfide oxidoreductase activity
Vocabulary: Biological Process
TermDefinition
GO:0045454cell redox homeostasis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0045454 cell redox homeostasis
molecular_function GO:0009055 electron carrier activity
molecular_function GO:0050220 prostaglandin-E synthase activity
molecular_function GO:0005515 protein binding
molecular_function GO:0015035 protein disulfide oxidoreductase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR004045Glutathione S-transferase, N-terminalPFAMPF13417GST_N_3coord: 73..139
e-value: 7.2E-12
score: 45.4
NoneNo IPR availableGENE3D1.20.1050.10coord: 201..336
e-value: 7.1E-11
score: 41.9
NoneNo IPR availableGENE3D3.40.30.10coord: 68..200
e-value: 1.1E-21
score: 76.9
NoneNo IPR availableSFLDSFLDG01182Prostaglandin_E_synthase_likecoord: 61..344
e-value: 0.0
score: 383.0
IPR034334Prostaglandin E synthase 2SFLDSFLDG01203Prostaglandin_E_synthase_likecoord: 56..342
e-value: 0.0
score: 382.7
IPR011767Glutaredoxin active sitePROSITEPS00195GLUTAREDOXIN_1coord: 73..89
IPR002109GlutaredoxinPROSITEPS51354GLUTAREDOXIN_2coord: 59..158
score: 11.891
IPR034335Prostaglandin E synthase 2, C-terminalCDDcd03197GST_C_mPGES2coord: 187..332
e-value: 1.11433E-76
score: 234.038
IPR010987Glutathione S-transferase, C-terminal-likeSUPERFAMILY47616GST C-terminal domain-likecoord: 190..330
IPR012336Thioredoxin-like foldSUPERFAMILY52833Thioredoxin-likecoord: 70..143

Blast
BLAST of TCONS_00025387-protein vs. Swiss-Prot (Human)
Match: PGES2 (Prostaglandin E synthase 2 OS=Homo sapiens GN=PTGES2 PE=1 SV=1)

HSP 1 Score: 273.478 bits (698), Expect = 1.172e-89
Identity = 137/272 (50.37%), Postives = 185/272 (68.01%), Query Frame = 0
Query:   72 TLYQYATCPFCCKVRSFLDYYGVDYEIVEVNPVSRKEIKFSEYRKVPFLTSKE----HQLNGSSLICSVLKTQLITESEVSKILTYYPILE--NEDGKKKSFDYQNIYNVMY------ETGIGKEAHDKVRDEMKWRRWVDEVFVHTLSPNIYRTWGESLQAMEYITKVGNFSDFERTLIYYSGAVAMYLIGKRLKHRHHLRNEVRESLYEETYRWLKAVGKN-PYQGGDQPNMADLNMYGVLSAIEGYDAFSDLLQNTNIGPWYQRMKTKV 330
            TLYQY TCPFC KVR+FLD++ + Y++VEVNPV R EIKFS YRKVP L ++E     QLN SS+I S LKT L++   + +I+TYYP ++  NE GK+ + ++ N Y +M       +   GKEA     +EMKWR+W D+  VH +SPN+YRT  E+L + +YI + G F   E  +  Y GA AMYLI KRLK RH L++ VRE LYE   +W+ AVGK+ P+ GG +PN+ADL +YGVL  +EG DAF DL+Q+T+I PWY R++  +
Sbjct:  103 TLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGKEVT-EFGNKYWLMLNEKEAQQVYGGKEART---EEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAI 370          
The following BLAST results are available for this feature:
BLAST of TCONS_00025387-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PGES21.172e-8950.37Prostaglandin E synthase 2 OS=Homo sapiens GN=PTGE... [more]
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