TCONS_00022304-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022304-protein
Unique NameTCONS_00022304-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1577

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022304-protein ID=TCONS_00022304-protein|Name=TCONS_00022304-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1577bp
GIPFRFQVNQMEQRKKHDEASEICDTIRLVCEDFPELKFAVENFILKDHD
GTDYDSMNHICQRYNKAIKNILALWKGRAPPPHMFKPPKKELLRHIINLC
FSHAIKEPEKLNIYEPFSPEVYGETSFDMVAQILEECKKSNEETFIDLGS
GVGQVVLQAAASNQFKECFGVEKAETPAMYAKAMDEQFRKWMDWFGKTYT
DFTLEKGDFLEDKWTEIINNSGFVFVNNFAFGPLVNHHLKERFQQMKEGA
QIISSREYCPLNFKFNKRNLSELGAMMRVTELKPKSEEQTVSWTGNVVSY
YLHVVDRTRLEKYFSILKKRKEGRDLDEDELSLYSESNVSVDTGKHEETL
EENLDELYLGTTTRHQWQVLNETLKQSRNDVKDEDEANTKKKKKKKKKIK
DDLSDPSSISTTSITQKSGNIQMKDKILQKYGHQKVRKAIANLPNTSPSL
TSSTSTANKSLKGRKKNNLYLAASSPSSSETDTSPEDDEDVDDDEEWVPP
VQQDKNNNKLKEKTKKKHLITASTTSKKKKEGIKSWQTNNSSKESKGNAD
TTNKKASSTTKKQKDIAAVKTASAKSNKKKNKEVSEKXAAVKTASAKSSK
KKNKEGPSKDFFTNLDRQVDEFYDSMKVKAKEFIRRINTEEYANRLQTMI
ECEQTKKKLLQREVTEMEQTVQQLITTGLTNFSNRLVELDLAVKTPLELL
STSTQLAEKRQDLENKVLNMEVEVFNLEEKYKNMCVARNVKNESLGLPPI
EEVMPTEQPITCQELENHRNELTSQLCGSILSALNHRKNLIDKQSSLNEQ
ISILEKITSPTASLPNEELDSYQAEEMSKDERLLRPRPVAYVPPRMIGED
QNQIVISPEGGASQSEITPTRRGRGRPRKEQEEEQEEKNSFVVTREMLTS
AIERNTSQVLEERAPIFFPNSLRNEETDEISKKFLQASSKLLQSSTCEMS
SHKGKWKPLQEIDSFRQISSSPEHVTNHMTSSSATIPSVIKETNPSHPKL
KDIEQRNHNTSTITTRPPNEQKPPDEEIHVSEEPKIMEPPIQPPSIALPS
IPPPPTKILIHDQAPVTGQHLQKVHKFNIYDNLQLSFLQQRDFLNRAPIV
TTHAITQRQPCATVTVSACSKATITPRLPSMCLQSSGPLTTPFSMDSLAQ
SSAMTMPQQQLHRIQNAAQNSIPIIHHPSTSVFFQAYPHGKHPINVLSKT
SKETDATKKPKRGRKRKTVDESVDMSSNIIVPGKHVKAHKQKRKDSTCTK
NNNNTIVDFKREVEDHFKTSLDQIHPQFHNRQQTTTQQPVMSSSSIKNIQ
IPLRVQPSDALAPSLHQQRPSNLDILKQAAFANLPERSTTTSGVLYQPLS
NPLATSSVSTTECKPAATLKTVQVAKTIIPVNTTGPNSLYALHNRIVEHP
VASSLNRTKNAPSFIQQPISTIAHVKNQTKSKKSKKEIQLPIQVIPHKLL
AAAPLAQSGHLHPVTHFIRPATHDSNLLRSMLLTSPQEATSAHKLLVMNP
PSTVHAHHPLAVAAASKPDQRLMILPEHLQPTRSPVVFLPSPAAPALPPS
RPASIIVDASRPNSSNASPTFPPPKPS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012513XLOC_012513Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022304TCONS_00022304Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR025789DOT1_dom
IPR000637HMGI/Y_DNA-bd_CS
IPR029063SAM-dependent_MTases
Vocabulary: Molecular Function
TermDefinition
GO:0018024histone-lysine N-methyltransferase activity
Vocabulary: Biological Process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006355 regulation of transcription, DNA-templated
molecular_function GO:0018024 histone-lysine N-methyltransferase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 643..677
NoneNo IPR availableCOILSCoilCoilcoord: 703..730
NoneNo IPR availableGENE3D3.40.50.150coord: 113..317
e-value: 1.1E-21
score: 76.8
NoneNo IPR availableCDDcd02440AdoMet_MTasescoord: 144..259
e-value: 0.00205481
score: 37.4095
IPR025789Histone-lysine N-methyltransferase DOT1 domainPFAMPF08123DOT1coord: 102..305
e-value: 4.7E-66
score: 222.1
IPR025789Histone-lysine N-methyltransferase DOT1 domainPROSITEPS51569DOT1coord: 1..318
score: 74.89
IPR000637HMG-I/HMG-Y, DNA-binding, conserved sitePROSITEPS00354HMGI_Ycoord: 868..879
IPR029063S-adenosyl-L-methionine-dependent methyltransferaseSUPERFAMILY53335S-adenosyl-L-methionine-dependent methyltransferasescoord: 15..316

Blast
[Close]
BLAST of TCONS_00022304-protein vs. Swiss-Prot (Human)
Match: DOT1L (Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens GN=DOT1L PE=1 SV=2)

HSP 1 Score: 399.823 bits (1026), Expect = 1.211e-114
Identity = 173/307 (56.35%), Postives = 228/307 (74.27%), Query Frame = 0 
Query:   15 KKHDEASEICDTIRLVCEDFPELKFAVENFILKDHDGTDYDSMNHICQRYNKAIKNILALWKGRAPPPHMFKPPKKELLRHIINLCFSHAIKEPEKLNIYEPFSPEVYGETSFDMVAQILEECKKSNEETFIDLGSGVGQVVLQAAASNQFKECFGVEKAETPAMYAKAMDEQFRKWMDWFGKTYTDFTLEKGDFLEDKWTEIINNSGFVFVNNFAFGPLVNHHLKERFQQMKEGAQIISSREYCPLNFKFNKRNLSELGAMMRVTELKPKSEEQTVSWTGNVVSYYLHVVDRTRLEKYFSILKKRK 321
            K HD A EI +TIR VCE+ P+LK A+EN++L D+D   ++SM  +C +YN+AI +I  LWKG   P  +   P   LLRHI+   ++H++ +PEKLN YEPFSPEVYGETSFD+VAQ+++E K ++++ F+DLGSGVGQVVLQ AA+   K  +GVEKA+ PA YA+ MD +FRKWM W+GK + ++TLE+GDFL ++W E I N+  +FVNNFAFGP V+H LKERF  MKEG +I+SS+ + PLNF+ N RNLS++G +MRV EL P   + +VSWTG  VSYYLH +DRT LE YFS LK  K
Sbjct:   29 KHHDAAHEIIETIRWVCEEIPDLKLAMENYVLIDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTDDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPL--KGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPK 333
The following BLAST results are available for this feature:
BLAST of TCONS_00022304-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
DOT1L1.211e-11456.35Histone-lysine N-methyltransferase, H3 lysine-79 s... [more]
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