TCONS_00022066-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022066-protein
Unique NameTCONS_00022066-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1492

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022066-protein ID=TCONS_00022066-protein|Name=TCONS_00022066-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1492bp
MMMDSNSSGPSNITGTFKRRRSSITQQLLNYQDMLTGLFMKRSSRSSFGS
SDGNDSTTSDLKPNNNNITQVEQNKDQNKDQNSILIDNDKSLTTPTNFNK
KHRHSFKDSTQADSDLIQLKSPTSPTNSTSPGSTTAPPTRRRSAECHSTS
PPYYATHTAENDRLHQLASAEQRLSTVVTPTATSFSREDLNEIFNITRDT
MEIEKSPNIHNNPAETRLNNTLNESFQDIPQSPDQHNIAIDESNFLLDNT
ITEETLQSCAPPPSNSIGNPIPQTNDNNNNTKDNENIKQTTLLDLSNPQN
TPVDTPCTTPPGGGGPSRSGSMSKLQMVCREIFMTEKQYVSDLQDIIEGY
IYHLKQKGDLDVESIFGNLEDIFEFNKEVLYQIEQCETDRFEIDPIQLAK
VFIEKARGFNNHYTHYCTNYPEASHFFSIIMQDPNIAAFFLERQKFVGHA
LSLESYLLKPVQRILKYHLLFRDILKRYEGSEDGYDIINTAVLAMTDVAE
YINEMKRLHENAVKVQEILNNVVYIDVPIDVYATGRLVLENSFKVQGARS
DRIMYLFEKLLLICKKREDQLLLFKEKIECCNMMLVESIAKDPLGFQIMR
FDNRKVNYTIIAKTTDIKKEWVKELKRLILENHAAVIPQTARQAILGEEK
AKSKYNSLQFHALDDTVMTNVRNLNKKPVLKSPMSSKENHLPMVGSKRES
NEKETFSPKRPLNAKAKEYLTDKKTTNRLTQSGSALTTQPQSPEKEKKEK
LPKWMKRHIKQKNSLDGTVNLDTSTEMSTEDLYIPQTGVVKSRSLESLKD
ALKDQEHESKAGSNILKDIINYNFDQQIDDVIQDVQPMQTLDVLPIETTM
HIMSRPTSSVLTNTETVQDGSVLTPTNIEQLEIPDPDQPVTRSYEFTSGI
RITKSNSLSLRKKGGSVDDILASSFEKKHQRWSSIPSDPSRLERLEHRLS
LLSDDHDESSNTSIKNMVRKVSNAFNSSFQAYEDSPRSHSTADSDVSRDL
GKLLGTPVKTEQQEHHSKLSFRRSTGGILDNITDAMDENIERNTRSQSDC
VTYKTETNLLEPTQNDPIEQQVENIVIDSNSDIEEKPIEIIDNQSKKDDS
NEDLSKRWSTDVDQVFDEVNADLDSIADSIASDTVKSDTEGAATEPTYEV
TSVGMDIAHRAAIVDQRLKEANNVDTVFSPMSTKRVNVEVKRVADRIKEY
KRLVDAEKRRTSWRRREPKSMNEMIESLETIKSTDNGLTPTYQNMRRRYR
SSRDFEGTSITSSTDPSPRSSCSSIKRSLSENFTSVLENSQSEPVSYSVT
PTTEVSYTSTFEQSTDVVDSVKTITDSIQTLNHKKDKALDNAEDITSRTE
RYKKALENFDARAKTLDEEKKARLKVNNNALEGRTRSENYDARTRLASAG
EMKMEQTVIVRRRLKTTASANVVCRNSGDWTRKAQTLSHPKRSGAIKRIP
RADSESNDDEQSQENKPKVAQPPKGNDSSSTEXTKSLPSGWI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012377XLOC_012377Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022066TCONS_00022066Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000219DH-domain
IPR011993PH_dom-like
IPR001849PH_domain
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 942..962
NoneNo IPR availableCOILSCoilCoilcoord: 1328..1369
NoneNo IPR availableCOILSCoilCoilcoord: 498..518
NoneNo IPR availableCOILSCoilCoilcoord: 1190..1210
NoneNo IPR availableGENE3D1.20.900.10coord: 319..526
e-value: 1.1E-48
score: 165.0
NoneNo IPR availableCDDcd00160RhoGEFcoord: 325..503
e-value: 8.36991E-37
score: 138.2
NoneNo IPR availableCDDcd13243PH_PLEKHG1_G2_G3coord: 485..632
e-value: 9.83604E-50
score: 174.076
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 328..504
e-value: 1.6E-35
score: 134.0
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 328..503
e-value: 3.8E-37
score: 128.2
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 324..505
score: 30.508
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 307..525
IPR011993PH domain-likeGENE3D2.30.29.30coord: 535..665
e-value: 1.6E-19
score: 69.3
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 513..645
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 530..630
score: 8.012

Blast
[Close]
BLAST of TCONS_00022066-protein vs. Swiss-Prot (Human)
Match: PKHG1 (Pleckstrin homology domain-containing family G member 1 OS=Homo sapiens GN=PLEKHG1 PE=1 SV=2)

HSP 1 Score: 290.041 bits (741), Expect = 8.452e-80
Identity = 146/324 (45.06%), Postives = 212/324 (65.43%), Query Frame = 0 
Query:  328 VCREIFMTEKQYVSDLQDIIEGYIYHLKQKGDLDV-----ESIFGNLEDIFEFNKEVLYQIEQCETDRFEIDPIQLAKVFIEKARGFNNHYTHYCTNYPEASHFFSIIMQDPNIAAFFLERQKFVGHALSLESYLLKPVQRILKYHLLFRDILKRYEGSEDGYDIINTAVLAMTDVAEYINEMKRLHENAVKVQEILNNVVYIDVPIDVYATGRLVLENSFKVQGARSDRIMYLFEKLLLICKKREDQLLLFKEKIECCNMMLVESIAKDPLGFQIMRFDNRKVNYTIIAKTTDIKKEWVKELKRLILENHAAVIPQTARQAIL 646
            V +EI  TE+ YV DL+ I+E Y+  ++ +  L +      ++FGN++DI+ FN E+L  +E CE D     P+ +A+ F+ K+  F+  YT YCTNYP +    +  M++  +A FF ERQ+ + H+L L SYLLKPVQRILKYHLL  +I    +   +GYD++  A+  M  VA +IN+MKR HE+AV++QEI + +     P D+ + G LVLE +F++Q A+++R ++LF+KLLLI KKR+D    +K  I C N+MLVE I K+PL F +  + N K+ +T+ AK+   K+ WV  LKRLILENHAA IP  A+QAIL
Sbjct:  117 VVQEILETERTYVQDLKSIVEDYLDCIRDQTKLPLGTEERSALFGNIQDIYHFNSELLQDLENCEND-----PVAIAECFVSKSEEFHI-YTQYCTNYPRSVAVLTECMRNKILAKFFRERQETLKHSLPLGSYLLKPVQRILKYHLLLHEIENHLDKDTEGYDVVLDAIDTMQRVAWHINDMKRKHEHAVRLQEIQSLLTNWKGP-DLTSYGELVLEGTFRIQRAKNERTLFLFDKLLLITKKRDDT-FTYKAHILCGNLMLVEVIPKEPLSFSVFHYKNPKLQHTVQAKSQQDKRLWVLHLKRLILENHAAKIPAKAKQAIL 432
The following BLAST results are available for this feature:
BLAST of TCONS_00022066-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PKHG18.452e-8045.06Pleckstrin homology domain-containing family G mem... [more]
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