TCONS_00020487-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00020487-protein
Unique Name	TCONS_00020487-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	881

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00020487-protein ID=TCONS_00020487-protein|Name=TCONS_00020487-protein|organism=Clytia hemisphaerica|type=polypeptide|length=881bp
MSSPLKQVGSRRLPPIKGGSNPGSASASPHNSRKKISKSAGGGSSPIIFK
DNENRKSPRSHHIDIESAFQQGPFRSPLLDFKQTLTAGLSPPLKQTKSTD
PTIFLHDLSLIDPEIIFVFLKNHPSLIQQYVSDYVTREDIEEWLDIKTLE
KYHERLSITSFDGCGIPPAASWRNTSCLERQQFMEKFIAEVQQVHGDVRG
GILNQLVDCCASGVNATGHNLYLADGEGKRIWKFLPESTKPVNLQIVREG
STIACYVAATKETICTSDIKDERYPEGVGVKDFQSGSVLCQPIISPNGDL
MGVMELTRLASMTSFSDTDNQIVNGYLTWGSIVLYYAEMYHSMHKQRRLN
EFLLNVTKSIFQDIVSMDTVIMKIMNFAQTLVDADRTSLFLLDNKTDELY
ARIFDIGTGLETKLQEEIRFPKSKGVAGHVATTGETLNIKNAYDDPRFNR
DIDVQTGYKTHTLLCMPIFIRGNLIGVVQMVNKKQGVFTTADEKAFQTFA
VYCGLALHHAKLYDKIRRSEQKYKVALEVLSYHSMCTEYEVDTVKNHDLV
NTKEQVGAFELNILDLETIEMSRIAIDLFTELFQTDSRFDPEELTRFTLT
VRRNYRRVPYHNWSHAFTVAHCMYCVVANSKGLLTGLEAVALYVSCLCHD
LDHRGKNNEWMKTESTPLAAVYTTSTLEHHHFNQTITILQHEGHNIFSHL
NSSEYKQILGIIKECILATDLAQFFGNKAKLNDIVNKGKFSWENSEHRRM
FRALSMTACDLSACAKPWKIQYETVKVIFQEFYAQGDEEKALGRTPVPMM
DRDTADKLPNHQVGFLVGICIPGYELLCKLVPGTKPLLDGAKKNFAVWSE
MVKKQNEEKEKEKEREKMKQLEEAKKENRDE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_011509	XLOC_011509	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00020487	TCONS_00020487	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR023088	PDEase
IPR003018	GAF
IPR003607	HD/PDEase_dom
IPR002073	PDEase_catalytic_dom
IPR029016	GAF_dom-like

Vocabulary: **Molecular Function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0005515	protein binding
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function	GO:0008081	phosphoric diester hydrolase activity
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 849..881
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 855..881
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..60
None	No IPR available	CDD	cd00077	HDc	coord: 610..783 e-value: 5.59836E-10 score: 57.3493
None	No IPR available	SUPERFAMILY	109604	HD-domain/PDEase-like	coord: 546..869
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 606..619 score: 56.43 coord: 675..691 score: 42.94 coord: 649..664 score: 43.62 coord: 773..789 score: 38.82 coord: 756..769 score: 56.0 coord: 635..648 score: 36.0
IPR003018	GAF domain	SMART	SM00065	gaf_1	coord: 179..344 e-value: 0.041 score: 12.9 coord: 366..517 e-value: 1.5E-29 score: 114.2
IPR003018	GAF domain	PFAM	PF01590	GAF	coord: 367..507 e-value: 9.2E-18 score: 65.1
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 608..774 e-value: 9.6E-7 score: 38.4
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 610..840 e-value: 5.5E-72 score: 242.2
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	GENE3D	1.10.1300.10		coord: 538..881 e-value: 2.3E-103 score: 345.5
IPR029016	GAF domain-like	GENE3D	3.30.450.40		coord: 176..344 e-value: 1.6E-11 score: 43.7
IPR029016	GAF domain-like	GENE3D	3.30.450.40		coord: 345..522 e-value: 1.2E-40 score: 138.5
IPR029016	GAF domain-like	SUPERFAMILY	55781	GAF domain-like	coord: 201..360
IPR029016	GAF domain-like	SUPERFAMILY	55781	GAF domain-like	coord: 346..533

Blast

[Close]

BLAST of TCONS_00020487-protein vs. Swiss-Prot (Human)
Match: PDE10 (cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A OS=Homo sapiens GN=PDE10A PE=1 SV=1)

HSP 1 Score: 580.482 bits (1495), Expect = 0.000e+0
Identity = 310/764 (40.58%), Postives = 461/764 (60.34%), Query Frame = 0

Query:  108 LSLIDPEIIFVFLKNHPSLIQQYVSDYVTREDIEEWLDIKTLEKYHERLSITSFDGCGIPPAASWRNTSCLERQQFMEKFIAEVQQVHGDVRGGILNQLVDCCASGVNATGHNLYLADGEGKRIWKFLPESTKPVNLQIV-----REGSTIACYVAATKETICTSDI-KDERYPEGVGVKDFQSG----SVLCQPIISPNGDLMGVMELTRLASMTSFSDTDNQIVNGYLTWGSIVLYYAEMYHSMHKQRRLNEFLLNVTKSIFQDIVSMDTVIMKIMNFAQTLVDADRTSLFLLDNKTDELYARIFDIGTGLETK----LQEEIRFPKSKGVAGHVATTGETLNIKNAYDDPRFNRDIDVQTGYKTHTLLCMPIFIRGNLIGVVQMVNKKQG-VFTTADEKAFQTFAVYCGLALHHAKLYDKIRRSEQKYKVALEVLSYHSMCTEYEVDTVKNHDL-VNTKEQVGAFELNILDLETIEMSRIAIDLFTELFQTDSRFDPEELTRFTLTVRRNYRRVPYHNWSHAFTVAHCMYCVVANSKGLLTGLEAVALYVSCLCHDLDHRGKNNEWMKTESTPLAAVYTTSTLEHHHFNQTITILQHEGHNIFSHLNSSEYKQILGIIKECILATDLAQFFGNKAKLNDIVNKGKFSWENSEHRRMFRALSMTACDLSACAKPWKIQYETVKVIFQEFYAQGDEEKALGRTPVPMMDRDTADKLPNHQVGFLVGICIPGYELLCKLVPGTKPLLDGAKKNFAVWSEMVKKQ 855
            L+ +  E +  +L  HP ++ ++VS+ V+ E +E+WL         +R +  S D       + +++T+       +  +I +     GD    +L +L         A G  LY        +  F P   K    +++      +G+T++ YVA +++T+   DI  DER+P G G+   +SG    SVLC PI++  GDL+G++EL R     +F  +  ++    L W S+ ++  ++   + KQ  LN+FLL+V+K+ F +IV++D+++  IM +A+ LV+ADR +LF +D+K  ELY+ +FDIG   E K      +EIRF   KG+AG VA TGE LNI +AY DPRFNR++D+ TGY T  +LCMPI  RG++IGVVQMVNK  G  F+  DE  F+ FAV+C LALH A +Y +IR SE  Y+V +E LSYHS+CT  E   +    L V   +++  F  +I   E +    I + +      T S F+ E+L RF ++V++NYRRVPYHNW HA TVAHCMY ++ N+  L T LE   L ++CLCHDLDHRG +N +++    PLAA+Y+TST+E HHF+QT++ILQ EGHNIFS L+SSEY+Q+L II++ I+ATDLA +FGN+ +L ++   G  +  N  HR     L MTACDL +  K W +   T   I+ EF+A+GDE K LG  P+PMMDRD  D++P  Q+GF   + IP Y  L +++P T+PLL   + N + W ++++ +
Sbjct:   11 LTGLTDEKVKAYLSLHPQVLDEFVSESVSAETVEKWL---------KRKNNKSEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGD-NQLLLYELSSIIKIATKADGFALYFLGECNNSLCIFTPPGIKEGKPRLIPAGPITQGTTVSAYVAKSRKTLLVEDILGDERFPRGTGL---ESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPVFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENM-WPGIFVYMVHRSCGT-SCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGE 759

The following BLAST results are available for this feature:

BLAST of TCONS_00020487-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00020487-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
PDE10	0.000e+0	40.58	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphod...	[more]

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TCONS_00020487-protein (polypeptide) - C. hemisphaerica