TCONS_00019533-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00019533-protein
Unique NameTCONS_00019533-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1090

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00019533-protein ID=TCONS_00019533-protein|Name=TCONS_00019533-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1090bp
MQEIKLYHHAEGHFLKDRLHKQATDAQCGRDSYCTGALVQPPVCEKRAYG
ELRPVTELKQDAMNFFKEFFKDNSNNLQEDKEALRMCEVMRSIEETGTYE
LTEQELAFGAKLAWRNAPRCIARKQWNSLKLFDFRHCQSAEEIFQRCLQH
IQYATNGGLIRSTISIFKKRTENNKETRIWNSQLIKYAGYTQPDGSVIGD
PNSCEFTEVCKTLGWQGKGGAFDVLPIVIQYKGGEPEFFEIPEEYILRVK
ISHPKYPKLANLGLEWYAVAIISDMSFDCGGQEFTCAPFNGWYTPHEIGV
RNFMDKQRYDMIKPIAEAFDLDTSDNLTLWKDKAAIEMTYAVLYSFKKFR
VTISDHHSLSEQFCEFMKSETNSRGGCPADWVWIVPSISGSLLPVFHQEM
INYKLKPSYEYQDNPWRHHRVQKRKFTNLKEISKFVLICIKMAFQYLRKR
PQLTVLYGSESGNAKRFARHLENTVNMTFWTKFSSLNKYEFVLDSTKPQF
LAIVTSTFGNGEAPSNAELFDIKLKKMVIKSELNRTQEDINQSKPLQHYK
YTVFALGSSAYPQFCAFGNDVNNKMRSLGAEEIYGIGEGDELNGQEQSFL
NWLGDCYIESCNRFDIIPTFGTDMADTYNNNLLSSEKKDKFLMDGRRSQW
SESKFRIVRADTERKQIKSLCNQISETNRLNVAPSKVIDVENLQTNQSRR
KTNFIRLSIQESHKQLQYEIGDSLAIFPENDHTLVERVLKKCRSSFDLDE
PIKLEINLNHDKKNDTDSWVSHDRISSPTTLATIFESLLDLNSPPTQSFL
SLLCSKATHPNDINTLQNLIQNEMEYKQWRNYNCPTIADVLDKFSSVQIS
VTFLITQLPLLKPRYYSISSSPRCHPNEIHLTVALLEYKTQGRDGMTRKG
VCSSWLDNLKPDDIVPCFVKKSNRMRIPETSDPLILVGPGTGIAPFRGFW
QELEYKSKHQHNGTKLPEVVLYTGCRSPQEDFLFQEEIQRCHESGVLNKV
HSAFSRVHGKAKNYVQHLMKQNAREMYDLLCKRNGHLFVCGGIEMAKDVK
ESIVEIIQECSQIDYVDALEATENLKLNGFYHEEVFAHTI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_010976XLOC_010976Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00019533TCONS_00019533Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001094Flavdoxin-like
IPR001709Flavoprot_Pyr_Nucl_cyt_Rdtase
IPR004030NOS_N
IPR008254Flavodoxin/NO_synth
IPR001433OxRdtase_FAD/NAD-bd
IPR029039Flavoprotein-like_dom
IPR003097FAD-binding_1
IPR012144NOS_euk
IPR017927Fd_Rdtase_FAD-bd
IPR017938Riboflavin_synthase-like_b-brl
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006809nitric oxide biosynthetic process
Vocabulary: Molecular Function
TermDefinition
GO:0010181FMN binding
GO:0016491oxidoreductase activity
GO:0004517nitric-oxide synthase activity
GO:0005506iron ion binding
GO:0050660flavin adenine dinucleotide binding
GO:0005516calmodulin binding
GO:0050661NADP binding
GO:0020037heme binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006809 nitric oxide biosynthetic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0005516 calmodulin binding
molecular_function GO:0050660 flavin adenine dinucleotide binding
molecular_function GO:0010181 FMN binding
molecular_function GO:0020037 heme binding
molecular_function GO:0005506 iron ion binding
molecular_function GO:0050661 NADP binding
molecular_function GO:0004517 nitric-oxide synthase activity
molecular_function GO:0016491 oxidoreductase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001094Flavodoxin-likePRINTSPR00369FLAVODOXINcoord: 454..467
score: 39.84
coord: 548..558
score: 44.6
coord: 572..591
score: 32.19
coord: 502..513
score: 46.74
IPR001709Flavoprotein pyridine nucleotide cytochrome reductasePRINTSPR00371FPNCRcoord: 980..991
score: 34.1
coord: 1036..1044
score: 34.99
coord: 900..909
score: 44.94
coord: 864..871
score: 73.42
coord: 718..728
score: 37.83
coord: 935..954
score: 56.21
coord: 1012..1028
score: 26.57
coord: 967..976
score: 35.17
IPR004030Nitric oxide synthase, N-terminalPFAMPF02898NO_synthasecoord: 56..416
e-value: 3.6E-159
score: 529.5
IPR004030Nitric oxide synthase, N-terminalSUPERFAMILY56512Nitric oxide (NO) synthase oxygenase domaincoord: 4..420
IPR008254Flavodoxin/nitric oxide synthasePFAMPF00258Flavodoxin_1coord: 455..602
e-value: 3.3E-28
score: 98.6
IPR008254Flavodoxin/nitric oxide synthasePROSITEPS50902FLAVODOXIN_LIKEcoord: 453..607
score: 20.643
NoneNo IPR availableGENE3D1.20.990.10coord: 706..845
e-value: 2.4E-29
score: 101.5
NoneNo IPR availableGENE3D2.40.30.10coord: 846..924
e-value: 4.1E-27
score: 93.7
NoneNo IPR availableGENE3D3.90.440.10coord: 137..249
e-value: 3.3E-47
score: 158.8
NoneNo IPR availableGENE3D3.90.1230.10coord: 250..358
e-value: 7.6E-44
score: 147.9
NoneNo IPR availableGENE3D3.40.50.80coord: 932..1087
e-value: 1.3E-34
score: 118.9
NoneNo IPR availableSUPERFAMILY52343Ferredoxin reductase-like, C-terminal NADP-linked domaincoord: 929..1086
IPR001433Oxidoreductase FAD/NAD(P)-bindingPFAMPF00175NAD_binding_1coord: 936..1050
e-value: 2.8E-13
score: 50.3
IPR029039Flavoprotein-like domainGENE3D3.40.50.360coord: 453..606
e-value: 7.8E-33
score: 113.0
IPR029039Flavoprotein-like domainSUPERFAMILY52218Flavoproteinscoord: 450..606
IPR003097FAD-binding, type 1PFAMPF00667FAD_binding_1coord: 680..905
e-value: 5.6E-56
score: 189.5
IPR012144Nitric-oxide synthase, eukaryotePIRSFPIRSF000333INOScoord: 1..544
e-value: 2.6E-210
score: 698.8
coord: 529..1090
e-value: 8.4E-165
score: 548.0
IPR017927Ferredoxin reductase-type FAD-binding domainPROSITEPS51384FAD_FRcoord: 680..928
score: 12.938
IPR017938Riboflavin synthase-like beta-barrelSUPERFAMILY63380Riboflavin synthase domain-likecoord: 664..923

Blast
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BLAST of TCONS_00019533-protein vs. Swiss-Prot (Human)
Match: NOS2 (Nitric oxide synthase, inducible OS=Homo sapiens GN=NOS2 PE=1 SV=2)

HSP 1 Score: 802.742 bits (2072), Expect = 0.000e+0
Identity = 426/1095 (38.90%), Postives = 632/1095 (57.72%), Query Frame = 0 
Query:    2 QEIKLYHHAEGHFLKDRLHKQATDAQCGRDSYCTGALVQPPVCEKRAYGELRPVTELKQDAMNFFKEFFKDNSNNLQEDKEALRMCEVMRSIEETGTYELTEQELAFGAKLAWRNAPRCIARKQWNSLKLFDFRHCQSAEEIFQRCLQHIQYATNGGLIRSTISIFKKRTENNKETRIWNSQLIKYAGYTQPDGSVIGDPNSCEFTEVCKTLGWQGKGGAFDVLPIVIQYKGGEPEFFEIPEEYILRVKISHPKYPKLANLGLEWYAVAIISDMSFDCGGQEFTCAPFNGWYTPHEIGVRNFMDKQRYDMIKPIAEAFDLDTSDNLTLWKDKAAIEMTYAVLYSFKKFRVTISDHHSLSEQFCEFMKSETNSRGGCPADWVWIVPSISGSLLPVFHQEMINYKLKPSYEYQDNPWRHH------RVQKRKFTNLKEISKFVLICIKMAFQYLRKRPQLTVLYGSESGNAKRFARHLENTVNMTFWTKFSSLNKYEFVLDSTKPQFLAIVTSTFGNGEAPSNAELFDIKLKK-MVIKSELNRTQEDINQSKPLQHYKYTVFALGSSAYPQFCAFGNDVNNKMRSLGAEEIYGIGEGDELNGQEQSFLNWLGDCYIESCNRFDIIPTFGTDMADTYNNNLLSSEKKDKFLMDGRRSQWSESKFRIVRADTERKQIKSLCNQISETNRLNVAPSKVIDVENLQTNQSRRKTNFIRLSIQESHKQLQYEIGDSLAIFPENDHTLVERVLKKCRSSFDLDEPIKLEINLNHDKKNDTDSWVSHDRISSPTTLATIFESLLDLNSPPTQSFLSLLCSKATHPNDINTLQNLIQNEMEYKQWRNYNCPTIADVLDKFSSVQISVTFLITQLPLLKPRYYSISSSPRCHPNEIHLTVALLEYKTQGRDGMTRKGVCSSWLDNLKPDDIVPCFVKKSNRMRIPE-TSDPLILVGPGTGIAPFRGFWQELEYKSKHQHNGTKLPEVVLYTGCRSPQEDFLFQEEIQRCHESGVLNKVHSAFSRVHGKAKNYVQHLMKQN-AREMYDLLCKRNGHLFVCGGIEMAKDVKESIVEIIQECSQIDYVDALEATENLKLNGFYHEEVFA 1087
            + +++ +   G   +D LH +A      R   C G+++ P    +    +  P  EL   A+ F  +++        E+  A R+  V + IE TGTY+LT  EL F  K AWRNAPRCI R QW++L++FD R C +A E+F+   +H++Y+TN G IRS I++F +R++   + R+WN+QLI+YAGY  PDGS+ GDP + EFT++C  LGW+ K G FDV+P+V+Q  G +PE FEIP + +L V + HPKY     L L+WYA+  +++M  + GG EF   PFNGWY   EIGVR+F D QRY++++ +     L+T    +LWKD+A +E+  AVL+SF+K  VTI DHHS +E F ++M++E  SRGGCPADW+W+VP +SGS+ PVFHQEM+NY L P Y YQ   W+ H      R  KR+   LK + K VL    +  + +  R ++T+L+ +E+G ++  A  L    +  F  K   ++KY       + + L +VTSTFGNG+ P N E    KLKK + +  ELN              ++Y VF LGSS YP+FCAF +D++ K+  LGA ++  +GEGDEL+GQE +F +W    +  +C  FD+       +   Y +N+                 W    +R+V    +  Q   L   +S  +  NV   ++   +NLQ+  S R T  + LS ++  + L Y  G+ L + P N   LV+ +L++        + ++LE             WVS  R+  P +L+      LD+ +PPTQ  L  L   AT   +   L+ L Q   EY +W+  N PT  +VL++F S+++S  FL++QLP+LKPR+YSISSS    P EIHLTVA++ Y T+   G    GVCS+WL++LKP D VPCFV+ ++   +PE  S P IL+GPGTGIAPFR FWQ+  + S  QH G +   + L  GCR P ED ++QEE+    + GVL+ VH+A+SR+ GK K YVQ +++Q  A E+  +L K  GHL+VCG + MA+DV  ++ +++    +++     +    LK    YHE++F 
Sbjct:   83 RHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLA-RVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEE-RLLLVVTSTFGNGDCPGNGE----KLKKSLFMLKELN------------NKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNV----------------TWDPHHYRLV----QDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDG-QGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEA-----LDESGSYWVSDKRL-PPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQPS-EYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDS--QHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFG 1129
The following BLAST results are available for this feature:
BLAST of TCONS_00019533-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
NOS20.000e+038.90Nitric oxide synthase, inducible OS=Homo sapiens G... [more]
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