TCONS_00019409-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00019409-protein
Unique Name	TCONS_00019409-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	601

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00019409-protein ID=TCONS_00019409-protein|Name=TCONS_00019409-protein|organism=Clytia hemisphaerica|type=polypeptide|length=601bp
MKLLRQTTAALMLLLLAIVSVSMVNGSINNETDKFIGSTNLYHGLPQYYS
VVLDSKAMSKLFEEMFQDYDMNVLPSVSGEALNISTGMYINDMVPINPIN
MHYSMDIYFRQYWRDHRLAYDHLLPDYIHKRFENQSYIKSFAFESNFVNR
VWKPDLFFSLVKTGENAKITKPNQLIRLSANGDIFYSQRLTMTVFCEMDL
YAFPFDKQTCPFYIESYAYSASQISLNWVEGGKPIIPPKFKDMLEFTFDD
HTYDHEVVDYGLGDMFHRLHINFKFSRNIQYYILQIYVPALLIVILSWVG
FWIDYRSTPARVALGITTVLTMITFSKSVRNLLPFVNYSKLIDWYLLVCF
FYVFMGLVEYAAVGVIDQKWKRKLEGLTNSIFGTTSNQTNGNNSQVATPN
TFEFTQFHRSISENSFLSIKKEDVGLAPGNGLAGPVNGGVADTSLQQPID
DSFGVGYLSRSPRGGGEHGEVLSKGSNDVTPTIFEETGNHAENGRGIRNE
AFDVNSSPSPSIPSNESFNGGFKLDFGASINSTNTLTDRRKKNRLNKFKS
TRQQMSARLLERQKKDLEVHIIDKISRYVYPISFLIYNVIYFTYAFAEWS
G

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_010902	XLOC_010902	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00019409	TCONS_00019409	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006028	GABAA/Glycine_rcpt
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	PRINTS	PR00253	GABAARECEPTR	coord: 282..302 score: 56.22 coord: 575..595 score: 34.09 coord: 308..329 score: 58.53 coord: 342..363 score: 47.59
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 273..285 score: 31.12 coord: 150..161 score: 35.52 coord: 104..120 score: 37.74 coord: 196..210 score: 52.58
IPR006201	Neurotransmitter-gated ion-channel	TIGRFAM	TIGR00860	TIGR00860	coord: 58..594 e-value: 5.0E-94 score: 313.6
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 60..278 e-value: 1.1E-38 score: 132.8
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 47..285 e-value: 7.4E-49 score: 165.7
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 59..278
None	No IPR available	GENE3D	1.20.58.390		coord: 286..600 e-value: 7.5E-45 score: 152.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 458..495
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 286..592 e-value: 9.5E-30 score: 104.3
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 281..381 coord: 514..599
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 196..210

Blast

[Close]

BLAST of TCONS_00019409-protein vs. Swiss-Prot (Human)
Match: GLRA2 (Glycine receptor subunit alpha-2 OS=Homo sapiens GN=GLRA2 PE=1 SV=1)

HSP 1 Score: 221.09 bits (562), Expect = 1.614e-65
Identity = 116/304 (38.16%), Postives = 171/304 (56.25%), Query Frame = 0

Query:   69 YDMNVLPSVSGEALNISTGMYINDMVPINPINMHYSMDIYFRQYWRDHRLAYDHLLPDYIHKRFENQSYIKSFAFESNFVNRVWKPDLFFSLVKTGENAKITKPNQLIRLSANGDIFYSQRLTMTVFCEMDLYAFPFDKQTCPFYIESYAYSASQISLNWVEGGKPIIPPKFKDMLEFTF-DDHTYDHEVVDYGLGDMFHRLHINFKFSRNIQYYILQIYVPALLIVILSWVGFWIDYRSTPARVALGITTVLTMITFSKSVRNLLPFVNYSKLIDWYLLVCFFYVFMGLVEYAAVGVIDQKWK 371
            YD  + P+  G  +N++  ++IN    +    M Y ++I+ RQ W D RLAY    PD             S   + + ++ +WKPDLFF+  K      +T  N+L+R+S NG + YS RLT+T+ C MDL  FP D QTC   +ES+ Y+ + +   W+  G P+   +   + +F   ++    +    Y  G  F  + + F   R + YY++Q+Y+P+LLIVILSWV FWI+  + PARVALGITTVLTM T S   R  LP V+Y K ID ++ VC  +VF  L+EYAAV  + ++ K
Sbjct:   58 YDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEY-PD------------DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDG-PVQVAEGLTLPQFILKEEKELGYCTKHYNTGK-FTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346

The following BLAST results are available for this feature:

BLAST of TCONS_00019409-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00019409-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GLRA2	1.614e-65	38.16	Glycine receptor subunit alpha-2 OS=Homo sapiens G...	[more]

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TCONS_00019409-protein (polypeptide) - C. hemisphaerica