TCONS_00019281-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00019281-protein vs. Swiss-Prot (Human)
Match: RN213 (E3 ubiquitin-protein ligase RNF213 OS=Homo sapiens GN=RNF213 PE=1 SV=3)

HSP 1 Score: 1092.8 bits (2825), Expect = 0.000e+0
Identity = 652/1593 (40.93%), Postives = 916/1593 (57.50%), Query Frame = 0

Query:    4 ASAVDDDKCSARVILSERGGMGKSLYVKNKERKLEEVINKSPPCRERRSRCHKNNVVVTIPIHNVEVSVEDVVDQLCAFEGHIENVFPRIYHFDIAPLVSRGLDNFIFNVVILGYLQTQTGKAWHKQQSDLCIFEITE------TANKKDLFKRYLQ----KLLPTTICKTPQEVIAM--FNRREDT-SNIYLELLFDKPYQRVYQYLHYYHANGQNLKDMVYVEQEVNRNVHQLLTLFLSSCGIRDPSWLELQNFVLFFNTQLEDFETNYFASAN---EDFPGFKTFVLKFLLRMSKDFATRSLH-DNEAAGEHMV-------------ELRKHWETEYHPYLFFNEQKDSFSFIGFKVVPNRNREGSMNLIEPESNRLIEDNVMSLELFERLQCNMINDIQHLQTDPYKMRDVDKLNLMGRVLGIYEVANPDSTYELTPDNMKKIFAIHMRLRCGIPVILMGETGCGKTRLIKYMCDLRVGASCIRNMVLIKVHGGVTALDIEEKIKRTKIIAKENMINYILYARGYDYKDENLPIEVRQNVEEEVKDHIKNKTKIRDEELLRTILFLDEANTSEAIGLIKEIMIDGTLNGKALNFDRYCIDVIAACNPYRRHSDVMIKRLESAGLGYHVTAEQSYEKFGDIPLRHLVYRVHPLPESMKPLVWDFGSLSNEVEFKYSRQIIDRCVGNEQLPRNDNFKDVLLTVLTKSQEYMRSKKNECSFVSLRDIERGVSVTSWFYRKMDLFSKFIVEDLQEDPTRYQIATEKLRK-----SLLLAVAVCYIAKLDERAEFIEYLKEFFTGPFALEDDTADVEKEIERFQKMFIDHLDLKDNIAKNKALCENLFMMVVCIELRIPLFIIGKPGSSKSLAKTIIQDNMQGNASRSPFFKKFKRINMTSYQCSPHSTSEGIIGVFNQAAKFQEQKILDEYTSVVVLDEVGLAEDSPKLPLKALHPLLEDGTDGSEDLTIDGSEAKHKRVSFVGISNWGLDPAKMNRGILLSRSLPDKKELAKTAREICTGNEDIKSKISPIMEPLAGAYFELYRTQKNTPKLKKLQKEEFFGLRDFYCLVKMVFCFAKACKGMPPLQQIELAVKRNFSGLEELNAWDFFRPKLLHLYQEDERPAQETPTLEMIQSSIRTTCPCLRSKGLETKCTSSRYLLIMTENYSALPMVEAMLQQNGVEPDVIFGSSFPRDQEFTQVCRDINRMKIAMETGKTIILLNMEKLYESLYDALNQYYVFLGGQSYVDLGLGTHRVKCRVDEKFRLIVVANKQVVYELFPIPLINRLEKHFLMMTSGLVGEQQEISNQLKEWAINFSRVKS---ESEKYFTPSDAFIGFTEDMCPSIVMQ---------LYQEDSQNVFEDGKRVLINIATPDSIFRLGKSRLQDEKDEILSI-YFDQQQHTSLAEFLNVFLESSSSNMEGKAINHFIQVTTFSRLMSKPE-EV--SDSLNHRISVKILDIVKYPTEFDFRKDLETSLKENGDDPCVIIVQHTETDRIDRD--VVACAQH-ICRETQR-KFNCHNTFFLFLVQLNTSLKSS--VGYHSS-WICTHIDDIRNNNF---SFMRQCQQPLSSLFQP 1535
            A+AV +D+    ++ SER G+GKSLYVK    K++  +N             KN  + TI + + +V    V+  L  F        P ++H D+   V  G+  F+F ++IL YL    GK W +    L I EI E      + +   L  R  Q     + P   C+ P+EVI M     R DT   + L     + +QR YQYL  ++ N Q+L    Y E  V     + L  FL  CG+ +PSW EL+NF  F N QL D E + F + +   +   GFK FV+ F++ M++DFAT SLH  +++ G+HMV              LRK WE+E HPY+FFN+   + +FIGF + PN N  GS++ I   + ++I+ +VM+ +L++ L    +        D  K+    KL  +   LGI +  +PD TYELT DNM KI AI MR RCGIPVI+MGETGCGKTRLIK++ DLR G +    + L+KVHGG TA  I  +++  + +A  N                                        +D+  L TILF DEANT+EAI  IKE++ D  ++G+ L  D   + +IAACNPYR+HS+ MI RLESAGLGY V+ E++ ++ G IPLR LVYRVH LP S+ PLVWDFG LS+  E  Y +QI+ R V  E +  ++N   V+  VL  SQ +MR  ++ECSFVSLRD+ER V V  WF+      S  ++  L    ++  ++     +     SL+LA+ VCY A L+++  + + +  FF  P+   DD+  +  EI R Q +F+D + L+  IAKN AL EN+FMMVVCIEL+IPLF++GKPGSSKSLAKTI+ D MQG A+ S  F+  K++++ S+QCSPHST +GII  F Q A+FQ+ K L +Y SVVVLDEVGLAEDSPK+PLK LHPLLEDG        I+   A HK+V FVGISNW LDPAKMNRGI +SR  P++ EL ++A+ IC+ +  ++ ++       A AY            + K Q +EFFGLRD+Y L+KMVF  AKA    P  Q I  AV RNFSG +++ A D F   L      + + ++E   +++I+ +I    P  +  G E +   SRYLL++T+NY AL +++    +   +P++IFGS FP+DQE+TQ+CR+INR+KI METGK ++LLN++ LYESLYDALNQYYV LGGQ YVDLGLGTHRVKCRV   FRLIV+  K VVY+ FPIPLINRLEKH+L + + L   Q+ I  +L  W   F  VK+   +    ++PSD FIG+  D C S+V+Q         L +E  Q V E+ K +L+N ATPD++ RL    L     E LS  YF +Q+H S A+FL   L   ++++E  AI  F ++TTFSRL++  + E+  S+         +L + ++ TE+ F K++   L       C I++  T+ +   R   ++A A++ +  E  + + N    F  F+ +L+   + +  VG+H   W   HIDD+R +        R     +S LF P
Sbjct: 1976 AAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNV------------KNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRSDTEPGMDLWEFCSETFQRPYQYLRRFNQN-QDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNIN--GSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVP----FNVDFDKLPRHKKLERLCLTLGIPQATDPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFAN----------------------------------------KDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSG-LHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLV--ESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEH----SAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPY---DDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGC-------IEDDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAY----------ETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSGKDDIQALDIFLANL-----PEAKCSEEVSPMQLIKQNIFG--PSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGDQQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQKVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLH--TADLERHAI--FTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTAK--CKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGRGTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAP 3469          

HSP 2 Score: 267.314 bits (682), Expect = 6.077e-71
Identity = 289/1197 (24.14%), Postives = 525/1197 (43.86%), Query Frame = 0

Query: 2019 FKKNCAQFFVDIVEEFCFSKHNNDTNTQQNEEVLKKIMRYTFTSRG----------DQTREFSPIADEADNSPVIRSFILQQLMKREV-EVDVYFDQYLRDNMQFAQDDEDKWNMCKLFVNCYEDNQSAELASQRGNKFITEEYITQLSQFLNTSITQLTINRNVHEISASLLKDVARARVAITHSCGLLSKLYIGDHEIKDADKDILRTFFPLLMRFCQEVCKNTEMHLFILKQIVFEHGYRELDHVIEMSE----YDWL---NMERENTDPANNTGN-DRFLVYGNAYKEIRDQMAKEALQ-------RNLNADLEPVA-----VVDELTTSLALLHESVFANYQPEPEQLNQM--------------MNRYQANALQETIANLQP----CQLERDIVEMLYHFSLFLNEVSNGVGMLRLLYLLARQPDACQGWYLPTMPSDNFQEVFNTNRRRGRHDGFNQFVPYQCPNGHVYVITECGRAMTNRPCPECGANIGGRDHTLDQQNRRVDGQRNNTLAGYSCGSHQQRPQFAAPERQLKPLNNLLQRLLINLSMLLGCFESNPNSILALIHQAPDHDVVGFFVTHLRLDFRLLREVLGKNNEDIMLLIHLFIRHL----------RTLNLNHLDHQGATVTQLPQPNGRNQFENDFDLIFVQSFVQSYNNDLEGTKRRCLDDLQVGADPLIRRLYEIDENRETPTSNFDVMRATQLWRYRQPLSINHMRMKLQEKFTQNGGEEFRQLYRFLNEEKYYAKSVKELPKLVEFYKLLHLRYKYRIDKKKAKEITIGDFLKDLSKEKGNKELYKRLQQTSKVVFRVWNQLSEDLKEHGPFKPDANFHPEKLDSKTKLKYFLVSTEGAGRCLQSLIRFLQYIQNDLLILYQQLPGAFIKV-VDINVLKETEVIRYTAEEDLLPILYLHCDYSLAIGQGTKMEYNFQEIERRFMEKVCYGKCMIE-RTLEPFKYRDNVQSSREFINMRKKVPQTEIAYEEQRKMLDELKHIDDLSNTLKAVETAIGFLSTHGGTPNQKYDEYLDTKLRYNPKHYLASKTMKKLLRLTHLCSAWLMLTV---ERAIRIHNNGQNPFTFDATIFTEPLEGKLLEEAKSSF---AKFDKKTMTSHLTEYMVLEFPDKDSNYD-----TYELWEALDNYMADK-NEMLGDQKKADLPYSEFIPEEIQLKHVYAYW 3142
            F++ C  FFVD+V   CF       N    +EV++ ++   F  +G          + T+  SP  D  D +PVIRS IL+ L+K    +V  Y  +YL    + A   EDK  +  LF+NC ED+   + ++   N  +   ++ +  +FL             +E S   L++VAR R+ +  +   LS+   G    K+      + +   + +FC  V +N    +++++++  + G   ++ V  +S+    + W+   ++ ++     ++ G  DR+LVYG+ YK +RD +AK  L+         L A   P +      +  L   +A+L+ S  A+  P PEQ   +              ++R+  + +  ++  L+       L+  + EM  H +  L    N   +L  L  LA  P      +LPTMP D   +      RR +  G  +   Y CPNGH   + ECGR M    C +C A IGG DH        V  + + T  G+  G+ Q+R      +R L P+  LL RLL +L++LLG  +S  +  L  I + P  D  GF   H+  D   L ++LG + ++ + ++HL +R L          R LN +         T+L     RN +E +   + +   ++  +  L         D ++ ++P+ + +Y              V+  +++W  R+ +++ +++  +++K   NG E    L+ FL +E    + VK LP+++   + L  +++   + ++ +  +I  FL   S +   + L+ R+     V    WN+L   L+ +G      ++    LD  T+ +  L    G G C  +L+ +L  + N+++   ++L        VD   + E  VI Y  E DL P++  +C Y +  G+ T  E++ ++I+R+ + +   GK  +  + +    YR +      F++++ K+ Q  +       +  +L+   D    L  VE  +GFLST GG PN + + Y    L+   +     K + +  +L H  + W  L+    E+ +R+H       +        P   KLL    S+F      D   +  H  E ++L+  +  +  +      + L + L +YM  K +E+L +        S+F PEEI L    + W
Sbjct: 4061 FRQMCNSFFVDLVSTICFKD-----NAPPEKEVIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELN--HLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGGPEMAKEK-----QCYLQQVKQFCIRV-ENDWHRVYLVRKLSSQRG---MEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATSLVDNSVPLLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNE--LLEPLKNLAFSPATMAHAFLPTMPEDLLAQA-----RRWK--GLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRR-DVVTCDRGLPPVVFLLIRLLTHLALLLGASQS--SQALINIIKPPVRDPKGFLQQHILKDLEQLAKMLGHSADETIGVVHLVLRRLLQEQHQLSSRRLLNFD---------TELSTKEMRNNWEKEIAAV-ISPELEHLDKTLPTMNNLISQDKRISSNPVAKIIYGDPVTFLPHLPRKSVVHCSKIWSCRKRITVEYLQHIVEQK---NGKERVPILWHFLQKEAEL-RLVKFLPEILALQRDLVKQFQ---NVQQVEYSSIRGFLSKHSSDGLRQLLHNRI----TVFLSTWNKLRRSLETNGEINLPKDYCSTDLDLDTEFEILLPRRRGLGLCATALVSYLIRLHNEIVYAVEKLSKENNSYSVDAAEVTELHVISYEVERDLTPLILSNCQYQVEEGRETVQEFDLEKIQRQIVSRFLQGKPRLSLKGIPTLVYRHDWNYEHLFMDIKNKMAQDSLPSSVISAISGQLQSYSDACEVLSVVEVTLGFLSTAGGDPNMQLNVYTQDILQMGDQTIHVLKALNR-CQLKHTIALWQFLSAHKSEQLLRLHKEPFGEISSRYKADLSPENAKLL----STFLNQTGLDAFLLELH--EMIILKLKNPQTQTEERFRPQWSLRDTLVSYMQTKESEILPEMA------SQF-PEEILLASCVSVW 5194