frizzled receptor 3 (polypeptide) - C. hemisphaerica

Overview
Namefrizzled receptor 3
Unique NameTCONS_00019225-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length643

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00019225-protein ID=TCONS_00019225-protein|Name=frizzled receptor 3|organism=Clytia hemisphaerica|type=polypeptide|length=643bp
MLPNVIKLTFALTFFLVGTGGARQRERCVPLINDHCKDLGYNATLIPNVK
AGIDKLDEAARRISEFSPLFQVNCYENFKFFICNMFLPVCHSINGNPTPV
YPCRHVCEEARKGCEPLMKKYSFTWPDVLNCEFLASNTKQNALCGSPPPS
KPTRKTPQTEVVPTAPPAWVKVVEQFPKVDHKRFKYPERPIIFLSFCYNL
YSIGYLIRVFGNYENIVCENSPQGQHALIDGMSSTSCAIVFFLLYFFGMA
SALWWVVLSVTWFLAAALKWGHEAIEKYSSLFHAVAWTVPTIQTIIALVT
RKVDTDMLAGVCYIGATNSENLLMFVALPLLIYLLIGTLFLIMGFVALIK
IRKELQRERNTNKLERLIIRIGIFSVLYSVPASIVVGCFIHEYNRLKRTE
QVSQDMLSCLKDPNCEKDLKPRTEIFYLRYFMLLVVGVTSGVWIWTSKTF
DSWKNFYRRRFPEKSSKQEEEKERLYKNSFAPTTSNLQSAHAPPRRRSSN
EALNQYTPASTVASHPAIAIQPGMYAQPATNFFFPIQQHPAVMQAHNLPV
SQAKIVDSSSRGFTVTPSSNMTSDYEHNEVFNNYENKLIQNGHDMMHRQA
NYAPSSSSEHYTASLPRNGRPLDPPASPKSMSSRSHYSNEAKM
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_010791XLOC_010791Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00019225TCONS_00019225Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000539Frizzled
IPR020067Frizzled_dom
IPR017981GPCR_2-like
Vocabulary: Biological Process
TermDefinition
GO:0007166cell surface receptor signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0004888transmembrane signaling receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007166 cell surface receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0016020 membrane
molecular_function GO:0005515 protein binding
molecular_function GO:0004888 transmembrane signaling receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000539Frizzled proteinPRINTSPR00489FRIZZLEDcoord: 425..445
score: 45.52
coord: 186..208
score: 55.13
coord: 327..349
score: 47.3
coord: 282..305
score: 44.5
coord: 239..263
score: 61.6
coord: 367..388
score: 58.0
IPR000539Frizzled proteinSMARTSM01330Frizzled_2coord: 167..463
e-value: 6.5E-136
score: 467.5
IPR000539Frizzled proteinPFAMPF01534Frizzledcoord: 179..459
e-value: 1.8E-112
score: 375.5
IPR020067Frizzled domainSMARTSM00063FRI_4coord: 27..149
e-value: 1.7E-29
score: 114.0
IPR020067Frizzled domainGENE3D1.10.2000.10coord: 19..141
e-value: 6.4E-30
score: 103.5
IPR020067Frizzled domainPFAMPF01392Fzcoord: 28..137
e-value: 3.5E-25
score: 88.8
IPR020067Frizzled domainPROSITEPS50038FZcoord: 23..147
score: 22.026
IPR020067Frizzled domainSUPERFAMILY63501Frizzled cysteine-rich domaincoord: 27..146
NoneNo IPR availableGENE3D1.20.1070.10coord: 178..479
e-value: 5.1E-21
score: 74.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 601..643
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 467..499
NoneNo IPR availableCDDcd07066CRD_FZcoord: 27..149
e-value: 6.29715E-36
score: 130.319
IPR017981GPCR, family 2-likePROSITEPS50261G_PROTEIN_RECEP_F2_4coord: 176..452
score: 33.526

Blast
[Close]
BLAST of frizzled receptor 3 vs. Swiss-Prot (Human)
Match: FZD4 (Frizzled-4 OS=Homo sapiens GN=FZD4 PE=1 SV=2)

HSP 1 Score: 358.607 bits (919), Expect = 1.346e-116
Identity = 188/510 (36.86%), Postives = 276/510 (54.12%), Query Frame = 0 
Query:   21 GARQRERCVPLINDHCKDLGYNATLIPNVKAGIDKLDEAARRISEFSPLFQVNCYENFKFFICNMFLPVC-HSINGNPTPVYPCRHVCEEARKGCEPLMKKYSFTWPDVLNCEFLASNTKQNALCGSPPPSKPTRKTPQTEVVP----------TAPPAWVK------------------VVEQFPKV----------------------DHKRFKYPERPIIFLSFCYNLYSIGYLIRVFGNYENIVCENSPQGQHALI-DGMSSTSCAIVFFLLYFFGMASALWWVVLSVTWFLAAALKWGHEAIEKYSSLFHAVAWTVPTIQTIIALVTRKVDTDMLAGVCYIGATNSENLLMFVALPLLIYLLIGTLFLIMGFVALIKIRKELQRE-RNTNKLERLIIRIGIFSVLYSVPASIVVGCFIHEYNRLKRTEQVSQDMLSCLKDPNCEKDLKPRTEIFYLRYFMLLVVGVTSGVWIWTSKTFDSWKNFYRRRFPEKSSKQEEEKERLYK 477
            G  +  RC P+    C++LGYN T +PN+  G +   +A  +++ F+PL Q  C    +FF+C++++P+C   IN    P+ PC  +C   ++ CEP++K++ F WP+ LNC         N +C   P  +      +T + P          +    WVK                    ++F  +                      D  RF YPERPIIFLS CYN+YSI Y++R+    E I C+     +  LI +G+ +T CAI+F L+YFFGMAS++WWV+L++TWFLAA LKWGHEAIE +SS FH  AW +P ++TI+ L+ R VD D L G+CY+G  N + L  FV  PL  YL+IGTLF+  G VAL KIR  LQ++   T+KLERL+++IG+FSVLY+VPA+ V+ C+ +E +        + D                   +  L+ FM L+VG+TSG+WIW++KT  +W+    R       K+E+      K
Sbjct:   38 GDEEERRCDPIRISMCQNLGYNVTKMPNL-VGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVYVPMCTEKIN---IPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCMEGPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEFTDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVGRERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLKWGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVVAPLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATCVIACYFYEISNWALFRYSADD---------------SNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCSNRLVNSGKVKREKRGNGWVK 528
The following BLAST results are available for this feature:
BLAST of frizzled receptor 3 vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FZD41.346e-11636.86Frizzled-4 OS=Homo sapiens GN=FZD4 PE=1 SV=2[more]
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