TCONS_00018475-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00018475-protein
Unique Name	TCONS_00018475-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	447

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00018475-protein ID=TCONS_00018475-protein|Name=TCONS_00018475-protein|organism=Clytia hemisphaerica|type=polypeptide|length=447bp
MAYYLLDKKIERFKMSSKKLWKEFIGKFSDHLTTDNVKKMSWNFEIPDGK
QENMTSLQMLQYLDHQKEITRDDISLLYDGIEYARRLDLKTMLDDFQASM
RVALVEENKQRGGRPRPKSDYDNCDYDSLNQGMYSNSANSIATYASPRQA
AASFNSDDNYPMVHEPRGYCLIINNTFNKDNSTITPDGKILGFRDGSDKD
KVSLENLFKWLKFNVKSYDKVSRQYMETLLQLYSDDDKNMSHDCFVCCIL
SHGYEKGFYCNDGIGMDFSDMWEFFMGDKCPQLVGKPKLFFIQACQGERK
ATGVMYRDSPLIPNATTHPVQEESREFGTEEGIVERPPGSGAPPPLIYSR
DADFSSFVATTPGTTAWRDSVAGSWFIQELIEVFKKHAETEALATLRQKI
NRGIARKAALVKAGEVAKMMSDGGLLTLTKAVYFNPGQSYEAWCHPF

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_010351	XLOC_010351	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00018475	TCONS_00018475	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR015917	Pept_C14A
IPR033139	Caspase_cys_AS
IPR002138	Pept_C14_p10
IPR001309	Pept_C14_p20
IPR001875	DED_dom
IPR011029	DEATH-like_dom
IPR029030	Caspase-like_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0008234	cysteine-type peptidase activity
GO:0004197	cysteine-type endopeptidase activity
GO:0005515	protein binding

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis
GO:0042981	regulation of apoptotic process

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
biological_process	GO:0042981	regulation of apoptotic process
molecular_function	GO:0004197	cysteine-type endopeptidase activity
molecular_function	GO:0008234	cysteine-type peptidase activity
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR015917	Peptidase C14A, caspase catalytic domain	PRINTS	PR00376	IL1BCENZYME	coord: 166..179 score: 40.04 coord: 280..298 score: 64.59 coord: 426..435 score: 40.91 coord: 366..377 score: 54.55
IPR015917	Peptidase C14A, caspase catalytic domain	SMART	SM00115	caspase_2	coord: 159..436 e-value: 9.3E-65 score: 231.1
IPR015917	Peptidase C14A, caspase catalytic domain	CDD	cd00032	CASc	coord: 160..434 e-value: 1.32088E-66 score: 214.387
None	No IPR available	PFAM	PF00656	Peptidase_C14	coord: 168..404 e-value: 2.4E-33 score: 116.0
None	No IPR available	GENE3D	3.40.50.1460		coord: 147..310 e-value: 1.8E-23 score: 82.5
None	No IPR available	GENE3D	3.30.70.1470		coord: 347..441 e-value: 3.3E-18 score: 64.9
None	No IPR available	GENE3D	1.10.533.10		coord: 21..98 e-value: 1.1E-5 score: 25.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 315..342
IPR033139	Peptidase family C14A, cysteine active site	PROSITE	PS01122	CASPASE_CYS	coord: 286..297
IPR002138	Peptidase C14, caspase non-catalytic subunit p10	PROSITE	PS50207	CASPASE_P10	coord: 351..436 score: 23.251
IPR001309	Peptidase C14, p20 domain	PROSITE	PS50208	CASPASE_P20	coord: 166..299 score: 37.901
IPR001875	Death effector domain	PROSITE	PS50168	DED	coord: 20..95 score: 8.61
IPR011029	Death-like domain	SUPERFAMILY	47986	DEATH domain	coord: 27..108
IPR029030	Caspase-like domain	SUPERFAMILY	52129	Caspase-like	coord: 157..437

Blast

[Close]

BLAST of TCONS_00018475-protein vs. Swiss-Prot (Human)
Match: CASPA (Caspase-10 OS=Homo sapiens GN=CASP10 PE=1 SV=3)

HSP 1 Score: 131.339 bits (329), Expect = 2.524e-33
Identity = 113/420 (26.90%), Postives = 178/420 (42.38%), Query Frame = 0

Query:    8 KKIERFKMSSKK--LWKEFIGKFSDHLTTDNVKKMSWNFEIPDGKQENMTSLQMLQYLDHQKEITRDDISLLYD-----------GIEYARR---------------------------LDLKTMLDDFQASMRVALVEENKQRGGRPRPKSDYDNCDYDSLNQGMYSNSANSIATYASPRQAAASFNSDDNYPMVHEPRGYCLIINN-TFNKDNSTITPDGKILGFRDGSDKDKVSLENLFKWLKFNVKSYDKVSRQYMETLLQLYSDDDKNMSHDCFVCCILSHGYEKGFYCNDGIGMDFSDMWEFFMGDKCPQLVGKPKLFFIQACQGERKATGVMYRDSPLIPNATTHPVQEESREFGTEEGIVERPPGSGAPPPLIYSRDADFSSFVATTPGTTAWRDSVAGSWFIQELIEVFKK 386
            +++ER   + ++  L++  + + S+ + ++N+K M +  +    K E MTSL  L +L+ Q +I  D+++ L D            IE  +R                            D+KT L+        AL +E+ Q        +   N     +++GM   SAN++ +  S ++AA        Y M    RG C+I+NN +F             L  R G+ KD   L ++F+WL F V  ++ V++  ME +LQ    +  +   DCFV CIL+HG     Y +D   +   ++   F   +CP+L  KPKLFFIQACQGE     V      L P      +Q+                            +ADF   +AT PG  ++R    GSW+IQ L    KK
Sbjct:  100 EEVERLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKDSLPKTE-MTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQIVTPPVDKEAESYQGEEELVSQTDVKTFLE--------ALPQESWQNKHAGSNGNRATNGAPSLVSRGMQGASANTLNSETSTKRAAV-------YRMNRNHRGLCVIVNNHSFTS-----------LKDRQGTHKDAEILSHVFQWLGFTVHIHNNVTKVEMEMVLQKQKCNPAHADGDCFVFCILTHGRFGAVYSSDEALIPIREIMSHFTALQCPRLAEKPKLFFIQACQGEEIQPSVSIEADALNPEQAPTSLQDS------------------------IPAEADFLLGLATVPGYVSFRHVEEGSWYIQSLCNHLKK 468

The following BLAST results are available for this feature:

BLAST of TCONS_00018475-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00018475-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
CASPA	2.524e-33	26.90	Caspase-10 OS=Homo sapiens GN=CASP10 PE=1 SV=3	[more]

You are here

TCONS_00018475-protein (polypeptide) - C. hemisphaerica