TCONS_00018471-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00018471-protein
Unique Name	TCONS_00018471-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	508

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00018471-protein ID=TCONS_00018471-protein|Name=TCONS_00018471-protein|organism=Clytia hemisphaerica|type=polypeptide|length=508bp
MEGTFLSNMFWMILCFILIFNTAVSGRRQTPEERLHSHLFGDQHHDLTAF
PLEKGSLDLNFRLKLFGADIETDTETLSVDVNFIQSWANKRLSWNPMDFG
NITDINIDPEAAWVPNLYVHGNLEEDKEYNGLLSTLLTKINLRHDGVQTW
LAPSTLLLKCAIIVSHFPFDTQHCHLQFGSFAFDSSKLNINVKPLDLDLY
EDSPEWELLESGHAKEYVTYPGSKTPYTDALYVLKIRRKALAPLKELVFP
NLALITLTMLVFVIPTDAGERIGYLFTTFLAIAFFMTDTIDTLPRNSLNA
PFCMVFMGVSTLSLSLLAVCLCISISCYYANTNLVKLPDKCKTFLRKSGK
FLGVNLKREFDGWRHMLNEIRNFEEENFIGSCSSGSLHEEVKKFALASHT
EHPTERAKSSPEQTPVQTRKDNSQHKCSLSEEEIDGVDPLFENPEDLRSV
HERLEILLSTFEEQDDSSWREMEWFLFSQVVDKICFVVFTSYFVLSLVFA
GIHIYEVY

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_010347	XLOC_010347	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00018471	TCONS_00018471	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 160..174 score: 47.66 coord: 78..94 score: 31.22 coord: 111..122 score: 24.1
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 247..495 e-value: 4.4E-17 score: 62.8
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 247..498
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 27..239 e-value: 1.4E-37 score: 128.7
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 33..239 e-value: 4.6E-30 score: 104.6
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 32..239
None	No IPR available	GENE3D	1.20.58.390		coord: 244..506 e-value: 1.6E-19 score: 69.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 400..431
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 160..174

Blast

[Close]

BLAST of TCONS_00018471-protein vs. Swiss-Prot (Human)
Match: ACHA6 (Neuronal acetylcholine receptor subunit alpha-6 OS=Homo sapiens GN=CHRNA6 PE=1 SV=1)

HSP 1 Score: 143.28 bits (360), Expect = 2.588e-37
Identity = 123/506 (24.31%), Postives = 230/506 (45.45%), Query Frame = 0

Query:    5 FLSNMFWMILCFILIFNTAVSGRRQTPEERLHSHLFGDQHHDLTAFPLEKGS--LDLNFRLKLFG-ADIETDTETLSVDVNFIQSWANKRLSWNPMDFGNITDINIDPEAAWVPNLYVHGNLEEDKEYNGLLSTLLTKINLRHDGVQTWLAPSTLLLKCAIIVSHFPFDTQHCHLQFGSFAFDSSKLNINV--KPLDLDLYEDSPEWELLESGHAKEYVTYPGSKTPYTDALYVLKIRRKALAPLKELVFPNLALITLTMLVFVIPTDAGERIGYLFTTFLAIAFFMTDTIDTLPRNSLNAPFCMVFMGVSTLSLSLLAVCLCISISCYYANTNLVKLPDKCKT-FLRKSGKFLGVNLKREFDGWRHMLNEI--RNFEEENFIGSCSSGSLHEEVKKFALASHTEHPTERAKSSPE--QTPVQTRKDNSQHKCSLSEEEIDGVDPLFENPEDLRSVHERLEILLSTFEEQDDSSWREMEWFLFSQVVDKICFVVFTSYFVLSLVFA 500
            FL     + LC    F     G     EERL   LF   H++    P+E  S  + ++F + +   A+++   + +  ++     W + +L W+PM++  I  + +  +  W P++ ++ N   D +  G      TK  L+++G+ TW  P+     C + ++ FPFD Q+C L+FGS+ +D +++++ +    +D++ + ++ EWE++++   K  + Y   +  YTD  Y   IRR  +     L+ P L +  LT+LVF +P+D GE++    +  L++  F+    +T+P  SL  P    ++  + + ++L  V     ++ +Y       +P   KT FL+   + L   ++   D  R   ++   R        G  +S   H E +      H     E A S       P+Q   +NS+H   + E+ I+ V  + EN   ++S +E  E+              E +W   + VVD+    VF   F++  VF 
Sbjct:    9 FLHGGLCLWLCVFTPFFKGCVG--CATEERLFHKLFS--HYNQFIRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRWDPMEYDGIETLRVPADKIWKPDIVLYNNAVGDFQVEGK-----TKALLKYNGMITWTPPAIFKSSCPMDITFFPFDHQNCSLKFGSWTYDKAEIDLLIIGSKVDMNDFWENSEWEIIDASGYKHDIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVVPLVGEYLLFTMIFVTLSIVVTVFVLNIHYRTPTTHTMPRWVKTVFLKLLPQVLL--MRWPLDKTRGTGSDAVPRGLARRPAKGKLAS---HGEPRHLKECFHCHKSNELATSKRRLSHQPLQWVVENSEHSPEV-EDVINSVQFIAEN---MKSHNETKEV--------------EDDWKYVAMVVDR----VFLWVFIIVCVFG 478

The following BLAST results are available for this feature:

BLAST of TCONS_00018471-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00018471-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA6	2.588e-37	24.31	Neuronal acetylcholine receptor subunit alpha-6 OS...	[more]

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TCONS_00018471-protein (polypeptide) - C. hemisphaerica