TCONS_00018439-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00018439-protein
Unique NameTCONS_00018439-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1973

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00018439-protein ID=TCONS_00018439-protein|Name=TCONS_00018439-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1973bp
MLRRIFKRKPKAPESTSNGRRRSSEIHLTEEEKDGLIVTNVNNDEDKTDN
YDELSFIVDYIGSDYVSEAQSVPLLMETLKRIKKQHHKTIRVDLVLKSGI
LKVIDNEQSGALLITAPLYAIALAAQEQLRGFETAFALNITRRRIHMCHV
FQAGSRLEATAIVRAIAVSFRSVAKDLKEKRENAGERVRSDSERAHSDTD
AVRKHGETVLDVVDATSTSHQKRKKFVPSEEDIVEGDKASDEEIVSVLVH
QSTDTVEQEAEESGKNKKPRGDSIEIQSEKSVDVPVIDLFEKALQAIQQH
DLKLLERCIDEGLSVDAIITSTSLTLLHHAVINNNAEITEFLLDKGADVN
KEGPKDQTALHFAAANGNGPIAMVLLAHNANVRATDSKFHTPLHLSAANL
QSLQVSVILVEHGARIEDNDIEGDRPVDLHPDLREIQNRLIQSNIDTFAS
AEIDRSRSNSNCSSTSSSFKSVSRSPSNSTNKMAYNRSPWRLRASSSLQS
IRDVDGDSLSPMSHRKTDIVSPSPASLRKETDEEILSDVIPTNKIASSIS
SPDPTKSDQEDREVLSGYSSARRDSTTDDSEFEARVVKGEFFSDDGIVTE
SEDEIRNMRDLIDQKTLHSGKGGLPGMSESFGKISRKNTVTNSLGLLVTL
SGNAECQSSILAHLCLPKASQQLINLAHSVVASTTNLTQIAQMLHNLFTV
SGPSGRKKCFDAGLLKTVVDLLDATEPIQSTCLQILNDMFKTENERDYSG
NMSGIPIEPLLTIVKNNDTDSYITDVISDQNTLNDKMKTRISRSSDSGYP
NSPSLVERSASIKKRNEDSDSSDVGTNGIASFSRSKSKIKNDSIPLSNLE
SSIGRGRSQSFNSSVDTINSVRDSSPSVNLRVNNGRYNSESESNSSSGHY
NSTKARRISKGSTCSVDNPISRPTSTRVGARHIAMKMLAASSRSHKLQEE
LAKPQILKLLLGCLVDPDDEIILQATETLANIAMNIETHLQLQVENTDEA
LFKLVDHNNLKIQYQAARGLVYLGHTDINDKYIYDYISGEDSNSTVVYME
EDGRSHIRGSTVENLVLTLTQPKGIYLLWGGAHNLPPSPNQRKSLRHTSS
KSRSKTIPSENQIINFILSTYQTFVHPIIFMRLLLHRFREPNAYKMFHLI
QDEQQGPMEHYAPLPIIHARLMRVWICWLENYAQDFVTFPTLKDELSILT
NPMRSIDGPYAPCASKLEQLLFKVADTASANTNVYRFESESHHNILYEQC
YKAIKEGKLPCSEDDCVYLISLQLYIEDICLYGQDFPQRLKTIESITMTR
LKQNFGSAILSSKHLLKRIKSQYEIIVSEQPTERNAKHNFVDCCQGMSGY
GCTFFKVKQRIPNSRSRKKFHISRLFGISAHRIVLLDDRTKVCVEKFHPK
YLHRTEQLEDSLTVKIILNRNKTNNRVIEMQLENRLIFKELSNHILTCRM
EVNFQGYENIDTQPWSLLSENLGTWGNMALQLHTSKNKTELIDDFSGEDN
RKRGRSTTTTNYPMSRLPNSTGVISSSAPKNYSHSAPAKQESSGWSGNAY
EVLSFLNLKGILRSRGGGGETPIVHPGSESNSEAGTPPHKDGVLGDSFST
TPPSHGSSIAMEAVGPSQRRGSRVSASQAHENTPMLDESHGTDHQDPSKF
AHATKMLTCQCPPDAVFDYLNLKEFSAFELLDHPKELARQITLIDHRMFC
SITSKDVLFRISLGSIKRHQKAESHVTVEKFAHRFNQMSNWIVNCIVSER
NIHRRAKLFKNFIETAKQCLELRNYNAVTAIIVAALGSAPVRRLVGTKEL
VEPEYLSWMHKMENLMDSRSNHKKYRETLRSSQTPAIPYFGIYLKDLTFI
TDGNPDYLKGGVVNLSKRRQVHVLLEEIRRFQKKRYNFQEVQEIREYLLS
KSFVSEDKLHQMSKKNEPTINSRFGSSYQSVSHYQYSDRRSSSSATTLFR
SGTNSRSSTRRSQQKGTPSATSV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_010342XLOC_010342Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00018439TCONS_00018439Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002110Ankyrin_rpt
IPR001895RASGEF_cat_dom
IPR020683Ankyrin_rpt-contain_dom
IPR011989ARM-like
IPR019748FERM_central
IPR011993PH_dom-like
IPR014352FERM/acyl-CoA-bd_prot_3-hlx
IPR000651Ras-like_Gua-exchang_fac_N
IPR006020PTB/PI_dom
IPR023578Ras_GEF_dom
IPR016024ARM-type_fold
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0005085guanyl-nucleotide exchange factor activity
GO:0005488binding
Vocabulary: Biological Process
TermDefinition
GO:0007264small GTPase mediated signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007264 small GTPase mediated signal transduction
molecular_function GO:0005488 binding
molecular_function GO:0005085 guanyl-nucleotide exchange factor activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 174..194
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1493..1544
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..25
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 452..488
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1567..1648
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 790..925
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1935..1973
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 251..277
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 503..581
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 180..201
NoneNo IPR availableCDDcd00020ARMcoord: 934..1017
e-value: 5.75144E-5
score: 42.6868
NoneNo IPR availableCDDcd00204ANKcoord: 318..429
e-value: 4.8561E-24
score: 99.7654
NoneNo IPR availableCDDcd00934PTBcoord: 55..170
e-value: 7.56334E-12
score: 63.6819
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 388..418
e-value: 8.3
score: 15.4
coord: 355..384
e-value: 0.29
score: 20.2
coord: 322..351
e-value: 1.4E-4
score: 31.2
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 355..387
score: 11.274
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 322..354
score: 11.327
IPR001895Ras guanine-nucleotide exchange factors catalytic domainSMARTSM00147RasGEF_3coord: 1678..1920
e-value: 5.3E-70
score: 248.6
IPR001895Ras guanine-nucleotide exchange factors catalytic domainGENE3D1.10.840.10coord: 1673..1945
e-value: 4.3E-72
score: 242.2
IPR001895Ras guanine-nucleotide exchange factors catalytic domainPFAMPF00617RasGEFcoord: 1686..1869
e-value: 1.8E-52
score: 178.0
IPR001895Ras guanine-nucleotide exchange factors catalytic domainPROSITEPS50009RASGEF_CATcoord: 1683..1919
score: 59.996
IPR001895Ras guanine-nucleotide exchange factors catalytic domainCDDcd00155RasGEFcoord: 1683..1915
e-value: 2.57058E-64
score: 219.817
IPR020683Ankyrin repeat-containing domainPFAMPF12796Ank_2coord: 327..420
e-value: 7.2E-13
score: 48.8
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 285..433
e-value: 1.0E-30
score: 105.8
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 296..429
score: 29.255
IPR020683Ankyrin repeat-containing domainSUPERFAMILY48403Ankyrin repeatcoord: 295..429
IPR011989Armadillo-like helicalGENE3D1.25.10.10coord: 434..824
e-value: 0.0047
score: 15.8
coord: 924..1245
e-value: 4.3E-10
score: 38.8
IPR019748FERM central domainPFAMPF00373FERM_Mcoord: 1240..1355
e-value: 3.9E-8
score: 33.6
IPR019748FERM central domainCDDcd14473FERM_B-lobecoord: 1244..1345
e-value: 1.14056E-6
score: 47.6262
IPR019748FERM central domainSUPERFAMILY47031Second domain of FERMcoord: 1234..1350
IPR011993PH domain-likeGENE3D2.30.29.30coord: 9..182
e-value: 3.3E-10
score: 39.1
IPR011993PH domain-likeGENE3D2.30.29.30coord: 1350..1493
e-value: 0.0013
score: 18.5
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 52..182
IPR014352FERM/acyl-CoA-binding protein, 3-helical bundleGENE3D1.20.80.10coord: 1246..1349
e-value: 5.0E-6
score: 26.2
IPR000651Ras-like guanine nucleotide exchange factor, N-terminalPROSITEPS50212RASGEF_NTERcoord: 1053..1225
score: 10.216
IPR006020PTB/PI domainPROSITEPS01179PIDcoord: 55..170
score: 10.061
IPR023578Ras guanine nucleotide exchange factor domainSUPERFAMILY48366Ras GEFcoord: 1104..1245
coord: 1029..1070
coord: 1666..1933
IPR016024Armadillo-type foldSUPERFAMILY48371ARM repeatcoord: 930..1024
coord: 622..770

Blast
[Close]
BLAST of TCONS_00018439-protein vs. Swiss-Prot (Human)
Match: RGRF2 (Ras-specific guanine nucleotide-releasing factor 2 OS=Homo sapiens GN=RASGRF2 PE=1 SV=2)

HSP 1 Score: 141.354 bits (355), Expect = 1.816e-33
Identity = 84/236 (35.59%), Postives = 131/236 (55.51%), Query Frame = 0 
Query: 1686 ELARQITLIDHRMFCSITSKDVLFRISLGSIKRHQKAESHVTVEKFAHRFNQMSNWIVNCIVSERNIHRRAKLFKNFIETAKQCLELRNYNAVTAIIVAALGSAPVRRLVGTKELVEPEYLSWMHKMENLMDSRSNHKKYRETLRSSQTPAIPYFGIYLKDLTFITDGNPDYLKGGVVNLSKRRQVHVLLEEIRRFQKKRYNFQEVQEIREYLLSKSF-VSEDKLHQMSKKNEPTI 1920
            ELA QITL+DH +F SI  ++ L +   G +K   K E    + K +  FN MSN + + I++  ++  RA   + ++  A  C  L NYN V  I  +AL  + + RL  T   V  +  + M K++  + S    K  RETL++   PA+PY G+YL DL FI +G P++ + G+VN SK R +  ++ EIR+FQ+  Y      ++ +YLL K   + ED L+++S K EP +
Sbjct: 1005 ELAEQITLLDHVIFRSIPYEEFLGQ---GWMKL-DKNERTPYIMKTSQHFNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEI-TSALNRSAIYRLKKTWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNPPAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTSYRIDHQPKVAQYLLDKDLIIDEDTLYELSLKIEPRL 1235
The following BLAST results are available for this feature:
BLAST of TCONS_00018439-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RGRF21.816e-3335.59Ras-specific guanine nucleotide-releasing factor 2... [more]
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