TCONS_00018348-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00018348-protein
Unique Name	TCONS_00018348-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1164

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00018348-protein ID=TCONS_00018348-protein|Name=TCONS_00018348-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1164bp
MESKMDTKLIQDLTTNKKFLLNFVKEWNESRLDMFALSQPNEKMQFSGVM
RFFFQDSGQKATTKCIRVTSDQSVADIMPTLIDKFCPDLKMLSMPNYELY
EIHGTGDVRKLNPKQRPLLVQLHWHNDDREGRFVLKNAEVKIQPVKFFEI
NQDEGQLKRRLSRREKKDLKKKRKEELARQNKKNQDKLLADKVYRELPES
SLTRTISNPEAVMRRRRQQKLEKRMKEFQNKGGPQTGGILKIFAESLKPE
IPYKTILASVKDNADVITKAALEKFLLPDENPIYFCIVMAIIAPGEANNP
GNVKERIIRSSDCPLAIQNSWPRSKGVITFHLRRKDDAPENTSKIPKDDK
KAKGRNQSSSQPPSQQPKPPPATRGPPPPLEQKLDYDIMPYFLELTPEGK
EISYKPKLYYIRAHETVIGSSRNPSPGVQYLQLFSPKILASHCSIVNEDG
CVSIIPHGPDADVRVSGKRIFDTTILSNGNVVQFGGLHTFRFCNPLDPAH
SEKSSIASEHGIPPYRPPTSPGMGSPPMSPISPELKEKILNEQIGAGVDD
DLDADVAETTFGVDGGIETEKIPRHIYSARSAENLLDEETVVLRQNFRNS
FKKHRQSAPNLLDRNLNEENLLPATLTFLENGKDAFFATVISEVNGAAVN
FKLAPTYTLYLVARHVYSPAYRPGLNPVDRSKVITSTTKRIATSVQQTIQ
ENDCLAGGLAFWMANASELLHFYRQDMDLGPLTQSAQAILAQSIQESFAL
LVNAMEDELALALPAFLDPSEEVDIHEHDIDAILNDDVLERAESVELLNW
NSDNDDRAFRMGPNGRPLSGEQWIRPAARIHQNGAPEMADVLYILSSAMS
LLRRCRVNAALTIQLFSQLFHYINMWIFNRIVLEPDLRLCSRSWGHKLRL
RLSFVEAWAERQGLELAADCHLARIVQAAYLLESSKDSHDDIVDISQQCF
KLNSLQLRCLLQNYQQESGESRIPQDLVETIVAVAESTADELTISDGREV
KLEEDVQLQLPFLLPEEGYSSDIIRGVPPGLQEFLEPLCDTGLCELSLNP
SSMGLWTVYQEPYDIDENDDPNRDSQLVEELPIQRVTIDKGKSGLGLSIC
AAKGVHSDFPGIYIKAVIKGGLADQDGRLEGGDQILSVNESSLIDVTQTQ
YDDFSFAISFLFSK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_010299	XLOC_010299	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00018348	TCONS_00018348	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR002710	Dilute_dom
IPR000159	RA_dom
IPR001478	PDZ
IPR008984	SMAD_FHA_domain
IPR029071	Ubiquitin-rel_dom

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 167..187
None	No IPR available	GENE3D	2.60.200.20		coord: 386..501 e-value: 1.1E-16 score: 60.2
None	No IPR available	GENE3D	3.10.20.90		coord: 229..343 e-value: 1.7E-19 score: 69.7 coord: 39..144 e-value: 4.3E-18 score: 65.2
None	No IPR available	GENE3D	2.30.42.10		coord: 1060..1154 e-value: 7.3E-14 score: 51.5
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 328..381
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 159..183
None	No IPR available	CDD	cd15471	Myo5p-like_CBD_afadin	coord: 631..1011 e-value: 4.76672E-146 score: 443.676
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 1083..1150 e-value: 2.29612E-10 score: 57.5767
None	No IPR available	CDD	cd00060	FHA	coord: 407..492 e-value: 0.00912326 score: 34.6694
IPR002710	Dilute domain	SMART	SM01132	DIL_2	coord: 864..970 e-value: 3.8E-34 score: 129.4
IPR002710	Dilute domain	PFAM	PF01843	DIL	coord: 864..967 e-value: 8.4E-32 score: 109.5
IPR002710	Dilute domain	PROSITE	PS51126	DILUTE	coord: 689..987 score: 36.425
IPR000159	Ras-associating (RA) domain	SMART	SM00314	RA_5	coord: 46..140 e-value: 4.6E-13 score: 59.4 coord: 236..337 e-value: 3.1E-13 score: 60.0
IPR000159	Ras-associating (RA) domain	PFAM	PF00788	RA	coord: 238..337 e-value: 3.4E-16 score: 59.6 coord: 47..137 e-value: 6.2E-11 score: 42.7
IPR000159	Ras-associating (RA) domain	PROSITE	PS50200	RA	coord: 46..140 score: 21.908
IPR000159	Ras-associating (RA) domain	PROSITE	PS50200	RA	coord: 236..337 score: 21.928
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 1093..1164 e-value: 1.5E-7 score: 41.1
IPR001478	PDZ domain	PFAM	PF00595	PDZ	coord: 1086..1150 e-value: 6.5E-9 score: 35.9
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 1085..1150 score: 16.144
IPR001478	PDZ domain	SUPERFAMILY	50156	PDZ domain-like	coord: 1076..1150
IPR008984	SMAD/FHA domain	SUPERFAMILY	49879	SMAD/FHA domain	coord: 389..495
IPR029071	Ubiquitin-related domain	SUPERFAMILY	54236	Ubiquitin-like	coord: 237..337
IPR029071	Ubiquitin-related domain	SUPERFAMILY	54236	Ubiquitin-like	coord: 47..137

Blast

[Close]

BLAST of TCONS_00018348-protein vs. Swiss-Prot (Human)
Match: AFAD (Afadin OS=Homo sapiens GN=AFDN PE=1 SV=3)

HSP 1 Score: 491.115 bits (1263), Expect = 3.537e-149
Identity = 306/825 (37.09%), Postives = 448/825 (54.30%), Query Frame = 0

Query:   17 KKFLLNFVKEWNESRLDMFALSQPNEKMQFSGVMRFFFQD-SGQKATTKCIRVTSDQSVADIMPTLIDKFCPDLKMLSMPNYELYEIHGTGDVRKLNPKQRPLLVQLHWHNDDREGRFVLKNAEVKIQPVKFF----EINQDEG---QLKRRLSRREKKDLKKKRKEELARQNKKN---------QDKLLADKVYRELPESSLTRTISNPEAVMRRRRQQKLEKRMKEFQNKGG-PQTGGILKIFAESLKPEIPYKTILASVKDNADVITKAALEKFLLPDENPIYFCIVMAIIAPG-EANNPGNVKERIIRSSDCPLAIQNSWPRSKGVITFHLRRK--DDAPENT-----SKIPKDDKKAKGRNQSSSQPPSQQPKPPPATRGPPPPLEQKLDYDIMPYFLELTP---------------EGKEISYKPKLYYIRAHETVIGSSRNPSPGVQYLQLFSPKILASHCSIVNEDGCVSIIPHGPDADVRVSGKRIFDTTILSNGNVVQFGGLHTFRFCNPLDPAHSEKSSIASEHGIPPYRPPTSPGMGSPPMSPISPELKEKILNEQIGAGVDDDLDADVAETTFGVDGGIE------TEKIPRHIYSAR------SAENLLDEETVVLRQN---FRNSFKKHRQSAPNLLDRNLNEENLLPATLTFLENGKDAFFATVISEVNGAAVNFKLAPTYTLYLVARHVYSPAYRPGLNPVDRSKVITSTTKRIATSVQQTIQENDCLAGGLAFWMANASELLHFYRQDMDLGPLTQSAQAILAQSIQESFALLVNAMEDELALALPAFLDPSEEVDIHEHDIDAILN 785
            ++ L + +  WN +RLD+F +SQP E ++F GVMRF+FQD +     TKCIRV+S  +  D++ TL +KF PD++MLS P Y LYE+H +G+ R+L+  ++PL+VQL+W+ DDREGRFVLKN    I P K      E  + EG     KR LS++EKK+ KK+ KE L + + K+         ++  LA +VY+++PE+S TRTISNPE VM+RRRQQKLEKRM+EF++  G P +GG L+I+A+SLKP IPYKTIL S  D AD     ALEK+ L  ENP  +CI   ++ PG + ++    KE I+   +CPL I   WP  KG++ F L+R+  D  P+ T      K PK  ++A G    S+ PP +                       +PY +EL+P               +G +   KPKLY ++   T +G+ +     +   QLF P I   HC + N DG V++ P   DA+  V G+RI +TT+L +G  VQFG  H F+F +P       K S+  + G+    P   PG+                                V ETTF + G I       T K    + S R      +AE  + +  + + Q     R   +    S P L         +LPA++ F E+ +D+F + +I+  N + V+FKL+PTY LY+  R+V S  YRP ++P +R+  + +   ++ + ++  IQ+   +AG LAFWMANASELL+F +QD DL  +T  AQ +LA  +Q +F  LV+ ++ EL   +PAFLD  EE  +    ID +L+
Sbjct:   10 RRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGE-RRLDIDEKPLVVQLNWNKDDREGRFVLKNENDAIPPKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKREKEALRQASDKDDRPFQGEDVENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSLKPNIPYKTILLSTTDPADFAVAEALEKYGLEKENPKDYCIARVMLPPGAQHSDEKGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDHIPKKTKKHLEGKTPKGKERADGSGYGSTLPPEK-----------------------LPYLVELSPGRRNHFAYYNYHTYEDGSDSRDKPKLYRLQLSVTEVGTEKLDDNSI---QLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVEGQRISETTMLQSGMKVQFGASHVFKFVDPSQDHALAKRSV--DGGLMVKGPRHKPGI--------------------------------VQETTFDLGGDIHSGTALPTSKSTTRLDSDRVSSASSTAERGMVKPMIRVEQQPDYRRQESRTQDASGPEL---------ILPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSNQYRPDISPTERTHKVIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLH 764

HSP 2 Score: 372.474 bits (955), Expect = 1.080e-107
Identity = 186/316 (58.86%), Postives = 231/316 (73.10%), Query Frame = 0

Query:  836 PEMADVLYILSSAMSLLRRCRVNAALTIQLFSQLFHYINMWIFNRIVLEPDLRLCSRSWGHKLRLRLSFVEAWAERQGLELAADCHLARIVQAAYLLESSKDSHDDIVDISQQCFKLNSLQLRCLLQNYQQESGESRIPQDLVETIVAVAESTADELTISDGREVKLEEDVQLQLPFLLPEEGYSSDIIRGVPPGLQEFLEPLCDTGLCELSLNPSSMGLWTVYQEPYDIDEN---DDPNRDSQLVEELPIQRVTIDKGKSGLGLSICAAKGVHSDFPGIYIKAVIKGGLADQDGRLEGGDQILSVNESSLIDVTQ 1148
            P++ DVL+ L+ AMSLLRRCRVNAALTIQLFSQLFH+INMW+FNR+V +PD  LCS  WG  +R +L  +EAWAE+QGLELAADCHL+RIVQA  LL   K + DDI +I+  CFKLNSLQL+ LLQNY     E  IP DL+E +V VAE+TADEL  SDGREV+LEED  LQLPFLLPE+GYS D++R +P GLQEFL+PLC  G C L  +  S G WT+Y E  D + +   ++      L +E  I  VT+ K ++G+GLSI AAKG   D  GIY+K+V+KGG AD DGRL  GDQ+LSV+  SL+ ++Q
Sbjct:  757 PKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMDKYAPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVTVAENTADELARSDGREVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLIPHTRSPGTWTIYFEGADYESHLLRENTELAQPLRKEPEIITVTLKK-QNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQ 1071

The following BLAST results are available for this feature:

BLAST of TCONS_00018348-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00018348-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
AFAD	3.537e-149	37.09	Afadin OS=Homo sapiens GN=AFDN PE=1 SV=3	[more]

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TCONS_00018348-protein (polypeptide) - C. hemisphaerica