TCONS_00014586-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00014586-protein
Unique Name	TCONS_00014586-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1411

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00014586-protein ID=TCONS_00014586-protein|Name=TCONS_00014586-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1411bp
MKLAHCTLIVFLIHTLVGPITLNDTATCPILQEGCECTHKFNGQLKIVCR
DVEVVSLSNLSSNVSFDIIIKSDKLKSINASSFPHPNVIRKLVLRDNSIK
TIEKGTFEGFNALVKLDLSNNHLVEIISSTFRGLSLSNLTELKLGSNRIL
QVSKTAFADLNIELLDLSNQKDAKNNDARLISYSDFLSFSFVKRVDLSGN
RLLCDCNMQWLPKWAAIDTNEVSNPSRCFYPAQLEGALLSGFDDTWDCAK
YKADFTIPEFHLYPYKDQVMFENDNIEYHCYTTWMEFSSIIWLSNGQAIP
SNEANVTISAAIDLTTGSLSSTLTIDKLSKKFHGNITCKADVWNSGVDQR
SRNVIIISSSQKTCPSNTSKTDRGNIFWPMSLSGAQVKSNCPFGSLVKNT
FAARDCGASGWSKFDVNECLFSDLTTQKLQLLYAKSRLHSFAELQNMAPI
FNTQFADDLHTIKTKYDLYFFCKILDDIRITYKGIDGTRYSLFYWNAIGA
LAEQHTSLTSMSEKVYGHTAMWRFRKLLEDYIEDQIQLETYRKRYYFHDH
HGLTASAYTLTTSSIGNELHCYLTVEGKVAVTCYPSIDYKANKAATILMT
LDVGRDVKVYKLTLLSFSTASFFQTPPKQSKADIDGGENEQERWTTSSIM
GLKFTAQLNDGSETRSIRVLRMAFIKSAFNLDNPRFVYWSNIDSQWKTSS
FCVKAFRSQRNASSFRCHNLEAGNMTYLAVLTKKPLPTILTANLLEPIVY
VGASLVCVLLILTLGIFIYFSYVRQVLYNRADSVALINLCIALLIAEIIF
ANGIHRVDDALLCTGVAAGLHYFILCALVWLGCGAVALLRLVKKKDRADV
KSYDPVMKYYLMGWGLPLIVCSITLAFKHSNYGTSEVCWLSRGLALGAFV
GIGGVISLANLIVFGLLHYSINRLFPAPIERREDDDSGSSDDENADENRN
NGDECSANQCRYKQPKIIVPQSNNVVIPKRKELLQSLHGGLLVLLLLIVT
VVNLIMVYSYKNAKARYLYFLFTYGGAISNFLVGFVIFYHFCFKRKDLRK
LLKQTFIHFRHKNAGVSEAIALVTHDDMERQNGSGEVGETENEKQESRDF
PIHAQHENLGVFGMSDHVISDGSQYIPSIAPEAQPSEVEDQQPDEKSEIL
DSSTDAHPQTFSKSAVTEVSESERLSNAPNSIGDCSLVSSNHNKRQKTPP
KPVDIPTNLKNFVPENWRPARRRMNKGASYYPYYASENAPISASLAYSSK
SSSLASTNVGGIPLYKNNHPTNMNGMRPRMAGPGPMPLQPPPPQRYQPTM
APPPPRMVASQQMYLTPTAPPLDAHPMTVLPLSSRQPVIEEVDTNTQSSR
NEEDFDVYPEINPVKSETELESELESDEEEAPTPLIVSPNLYIPMPHVSI
KQFILRNETSV

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_008161	XLOC_008161	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00014586	TCONS_00014586	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR003591	Leu-rich_rpt_typical-subtyp
IPR032675	L_dom-like
IPR000832	GPCR_2_secretin-like
IPR001611	Leu-rich_rpt
IPR013783	Ig-like_fold
IPR007110	Ig-like_dom
IPR017981	GPCR_2-like

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Molecular Function**
Term	Definition
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding
GO:0004888	transmembrane signaling receptor activity

Vocabulary: **Biological Process**
Term	Definition
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007166	cell surface receptor signaling pathway

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007166	cell surface receptor signaling pathway
biological_process	GO:0007186	G-protein coupled receptor signaling pathway
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0004930	G-protein coupled receptor activity
molecular_function	GO:0005515	protein binding
molecular_function	GO:0004888	transmembrane signaling receptor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003591	Leucine-rich repeat, typical subtype	SMART	SM00369	LRR_typ_2	coord: 136..159 e-value: 0.3 score: 20.2 coord: 110..133 e-value: 7.4 score: 14.3 coord: 90..109 e-value: 160.0 score: 3.5
IPR032675	Leucine-rich repeat domain, L domain-like	GENE3D	3.80.10.10		coord: 25..254 e-value: 1.2E-22 score: 79.6
IPR032675	Leucine-rich repeat domain, L domain-like	SUPERFAMILY	52058	L domain-like	coord: 85..229
IPR000832	GPCR, family 2, secretin-like	PFAM	PF00002	7tm_2	coord: 745..1024 e-value: 6.4E-21 score: 74.7
IPR001611	Leucine-rich repeat	PFAM	PF13855	LRR_8	coord: 69..123 e-value: 6.3E-10 score: 38.6
None	No IPR available	GENE3D	1.20.1070.10		coord: 738..1069 e-value: 6.5E-20 score: 70.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 932..957
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1133..1210
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1341..1385
None	No IPR available	CDD	cd00096	Ig	coord: 279..340 e-value: 0.00341896 score: 36.3131
IPR013783	Immunoglobulin-like fold	GENE3D	2.60.40.10		coord: 255..363 e-value: 5.5E-6 score: 25.9
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 258..355 score: 9.464
IPR007110	Immunoglobulin-like domain	SUPERFAMILY	48726	Immunoglobulin	coord: 258..341
IPR017981	GPCR, family 2-like	PROSITE	PS50261	G_PROTEIN_RECEP_F2_4	coord: 745..1045 score: 19.667

Blast

[Close]

BLAST of TCONS_00014586-protein vs. Swiss-Prot (Human)
Match: AGRA2 (Adhesion G protein-coupled receptor A2 OS=Homo sapiens GN=ADGRA2 PE=1 SV=2)

HSP 1 Score: 137.502 bits (345), Expect = 2.126e-32
Identity = 102/427 (23.89%), Postives = 185/427 (43.33%), Query Frame = 0

Query:   28 CPILQEGCECTHK----FNGQL------KIVCR--DVEVVSLSNLSSNVSFDIIIKSDKLKSINASSFPHPNVIRKLVLRDNSIKTIEKGTFEGFNALVKLDLSNNHLVEIISSTFRGLSLSNLTELKLGSNRILQ--VSKTAFADLNIELLDLSNQKDAKNNDARLISYSDFLSFSFVKRVDLSGNRLLCDCNMQWLPKWAAIDTNEVSNPSRCFYPAQLEGALLSGFDDTWDCAKYKADFTIPEFHLYPYKDQVMFENDNIEYHCYTTWM-EFSSIIWLSNGQAIPSNE-ANVTISAAIDLTTGSLSSTLTIDKLSKKFHGNITCKADVWNSGVDQRSRNVIIISSSQKTCPSNTSKTDRGNIFWPMSLSGAQVKSNC--------PFGSLVKNTFAARDCGASG-WSKFDVNECLFSDLTTQKL 429
            CP+    C+C+ +     +G +      ++VC   D+       L  N +  +++ ++K+  +   SF   +++ KL LR+N I T++ G F G   L +LDLSNN +  + S TF+GL             R+L+  +S   F+ L   + D                         +K VDL    L CDC+++WL  WA   + ++S  + C YP+ L    L    +   C   +    +   HL P   QV+F+ D + + C  +++   + I W  N   +  +E A + ++ ++      ++S LT+  +     G   C   +   G   +   ++++ +S   CP+     +RG+  WP +L+G     +C        P G     T A+R C  +G W   D + CL+++  T+ L
Sbjct:   37 CPLSIRSCKCSGERPKGLSGGVPGPARRRVVCSGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLP------------RLLRLNISGNIFSSLQPGVFD---------------------ELPALKVVDLGTEFLTCDCHLRWLLPWAQNRSLQLSEHTLCAYPSALHAQALGSLQEAQLCC--EGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGEWECTVSM-AQGNASKKVEIVVLETSASYCPAERVANNRGDFRWPRTLAGITAYQSCLQYPFTSVPLGGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVL 427

HSP 2 Score: 98.2117 bits (243), Expect = 2.127e-20
Identity = 109/454 (24.01%), Postives = 187/454 (41.19%), Query Frame = 0

Query:  612 LTLLSFSTASFFQTPPKQSKADIDGGENEQERWTTSSIMGLKFTAQLNDGSETRSIRVLRMAFIKSAFNLDNPRFVYWSN---IDSQWKTSSFCVKAFRSQRNASSFRCHNLEAGNMTYLAVLTKKPLPTILTANLLEPIVYVGASLVCVLLILTLGIFIYFSYVRQVLYNRADSVALINLCIALLIAEIIFANGIHRVDDALLCTGVAAGLHYFILCALVWLGCGAVALLRLVK------KKDRADVKSYDPVMKYYLMGWGLPLIVCSITLAFKHSNY-GTSEVCWLSRGLALGAFVGIGGVISLANLIVFGLLHYSINRL-FPAPIERREDDDSGSSDDENADENRNNGDECSANQCRYKQPKIIVPQSNNVVIPKRKELLQSLHGGLLVLLLLIVTVVNLIMVYSYK--NAKARYLYFLFT---YGGAISNFLVGFVIFYHFCFKRKDLR 1049
            L LL F     F +    S+    G     +R   ++ +    T+    G+ T  + V    + + A     P   +WS     ++   TS  C +   SQ N S+  C +L  GN+  L  L+  P         L P+VY   +L+ + L  T  I  Y      +  +R     L+NLC  + +   +FA GI   +  ++C  V   LHY  L  L+W+G  A  L + +       ++    + +  P++++YL+  G+PLI+C IT A    NY   S  CWL    +LGAF      I +A +++   +++    L    P+ +     +  +  E  +E R +     +         ++   S  V  P   E   SL+   + L  L+ T    + +++        R+L  +     YG A S   +G  +F H C +R+D+R
Sbjct:  643 LQLLVFRNGRLFHSHSNTSR---PGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGA----EPVAAWWSQEGPGEAGGWTSEGC-QLRSSQPNVSALHCQHL--GNVAVLMELSAFPREVGGAGAGLHPVVYPCTALLLLCLFAT--IITYILNHSSIRVSRKGWHMLLNLCFHIAMTSAVFAGGITLTNYQMVCQAVGITLHYSSLSTLLWMGVKARVLHKELTWRAPPPQEGDPALPTPSPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAF-----YIPVALILLITWIYFLCAGLRLRGPLAQNPKAGNSRASLEAGEELRGSTRLRGSGPLLSDSGSLLATGSARVGTPGPPEDGDSLYSPGVQLGALVTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASA--LGLFVFTHHCARRRDVR 1077

The following BLAST results are available for this feature:

BLAST of TCONS_00014586-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00014586-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
AGRA2	2.126e-32	23.89	Adhesion G protein-coupled receptor A2 OS=Homo sap...	[more]

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TCONS_00014586-protein (polypeptide) - C. hemisphaerica