TCONS_00014480-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00014480-protein
Unique Name	TCONS_00014480-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	976

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00014480-protein ID=TCONS_00014480-protein|Name=TCONS_00014480-protein|organism=Clytia hemisphaerica|type=polypeptide|length=976bp
MKTKEKSNWTNCFGSIVQVQAQLCHTEISKGIQLFIRISLKKDIEDGMDV
NLPVTRLKKTTDSFIQWRDKEYATAWGLNFVSEKDARRFLRLLASQEEKT
TPKRKDSDESNSSVGSRSSKRLSSSFGSQQSLDFSNPPSISVTSEEKSEK
TPIIRKPLVPPKPKSAHSTSASDIGKLPASSLDIENESEDIPVGYDPVEY
DYLMNEKDQESDEFNLGLSASGNKSGSTNSLFLPKEFSADDSLSGISEDF
QDTRPPSVVNLTRQMMSTRKAAWLLVKCLLQHSKKGRLEMSNHRKWRKYW
VALKGVELLFFQADEKTVTTEDMNEPTFQLDVDSSLVQAVPEYTRLENVF
SICTKQGNAYYLQATSQTETENWMHYIHTSAAAAFARKRGLENITPLLLQ
EIETLQKKLLSEEKLLKMAVLQLKIEKESHIRQNITDQIISWEESLEDIH
ATNFRLRCYIAAIESTHIPNPQELLTHVSRPTKHALSKLGLFSVTSFISY
VNTKNYVCLTTTAASNEKRAKNVRSTKYKSATNGGIKARFLSSLKIADDN
VVTAIRNRHSPQTKNRRTRSDRYSSDESNSSHASSRSGARKFGRVGDLLY
IQLPDARSCCLPYEPNLKICELMERVCMKENFDSLDYFMMLMMNDNNKHG
LLDYTIPKDNVLLDTFNYTRLKLCPKLQYDVTLTNPADYEHGAFGLDMEQ
TLDERIMVTFVEDGSPARKSGIVVEDEVIEINGQNLRVINNSFNDILEVM
NVSSSINLKLRSKRIDDPKKTFQTTESLISFLVCPPPPKSLQPDLSDDLL
NTLIVPAPTDLEESTTSSYHSASDKPSLGKEAKVEDIDDFLHQTEQVNMM
TREMNSIPIERSTSTAHSRKPGVHLRKAILELRDTEKTYVKNLRILLERY
LIPLKEENFLPKDEAELMVNNVREIFDFQSTFFERLKSIIRNDSNFDEFT
ETKQFQVSFLLFLLCVFLDLPGGPIN

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_008100	XLOC_008100	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00014480	TCONS_00014480	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001478	PDZ
IPR001849	PH_domain
IPR011993	PH_dom-like
IPR000697	WH1/EVH1_dom
IPR000219	DH-domain

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding
GO:0005089	Rho guanyl-nucleotide exchange factor activity

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005515	protein binding
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001478	PDZ domain	SMART	SM00228	pdz_new	coord: 692..764 e-value: 1.5E-5 score: 34.5
IPR001478	PDZ domain	PROSITE	PS50106	PDZ	coord: 680..750 score: 10.174
IPR001478	PDZ domain	SUPERFAMILY	50156	PDZ domain-like	coord: 693..762
IPR001849	Pleckstrin homology domain	SMART	SM00233	PH_update	coord: 268..384 e-value: 4.6E-9 score: 46.1
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 281..382 score: 13.597
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 2..110 e-value: 4.4E-5 score: 23.1
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 262..391 e-value: 3.7E-17 score: 61.5
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 56..94
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 284..382
None	No IPR available	PFAM	PF15410	PH_9	coord: 270..382 e-value: 1.5E-12 score: 47.9
None	No IPR available	GENE3D	1.20.900.10		coord: 855..960 e-value: 9.9E-16 score: 57.2
None	No IPR available	GENE3D	2.30.42.10		coord: 555..778 e-value: 9.1E-10 score: 38.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 555..588
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 98..192
None	No IPR available	CDD	cd00992	PDZ_signaling	coord: 679..761 e-value: 2.62906E-7 score: 48.3319
IPR000697	WH1/EVH1 domain	PFAM	PF00568	WH1	coord: 57..95 e-value: 5.6E-5 score: 22.9
IPR000697	WH1/EVH1 domain	PROSITE	PS50229	WH1	coord: 1..100 score: 10.402
IPR000219	Dbl homology (DH) domain	PFAM	PF00621	RhoGEF	coord: 879..945 e-value: 8.6E-10 score: 39.0
IPR000219	Dbl homology (DH) domain	PROSITE	PS50010	DH_2	coord: 874..976 score: 12.117
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 868..946

Blast

[Close]

BLAST of TCONS_00014480-protein vs. Swiss-Prot (Human)
Match: TIAM2 (T-lymphoma invasion and metastasis-inducing protein 2 OS=Homo sapiens GN=TIAM2 PE=2 SV=4)

HSP 1 Score: 280.411 bits (716), Expect = 2.940e-78
Identity = 217/723 (30.01%), Postives = 343/723 (47.44%), Query Frame = 0

Query:  269 RKAAWLLVKCLLQHSKKGRLEMSNHRKWRKYWVALKGVELLFFQADEKTVTTEDMNEPTFQLDVDSSLVQAVPEYTRLENVFSICTKQGNAYYLQATSQTETENWMHYIHTSAAAAFARKRGLENITPLLLQEIETLQKKLLSEEKLLKMAVLQLKIEKESHIRQNITDQIISWEESLEDIHATNFRLRCYIAAIESTHIPNPQELLTHVSRPTKHALSKLGLFSVTSFISYVNTKNYVCLTTTAASNEKRAKNVRSTKYKSATNGGIKARFLSSLKIADDNVVTAIRNRHSPQTKNRRTRSDRYSSDESNSSHASSRSGARKFGRVGDLLYIQLPDARSCCLPYEPNLKICELMERVCMKENFDSLDYFMML--MMNDNNKHGLLDYTIPKDNVLLDTFNYTRLKLCPKLQYDVTLTNPADYEHGAFGLDMEQTLDERIMVT--FVEDGSP---ARKSGIVVEDEVIEINGQNLRVINNSFNDILEVMNVSSSINLKLRSKRIDDPKKTFQTTESLISFL------VCPPPPKSLQPDLSDDLLNTLIVPAPTDLE---ESTTSSYHSASDKPSLGKEAKVEDIDDFLHQTEQVNMMTR-----EMNSIPIERSTSTAHSRKPGVH------LRKAILELRDTEKTYVKNLRILLERYLIPLKEENFLPKDEAELMVNNVREIFDFQSTFFERLKSIIRNDSNFDEFTETKQFQVSFLLFLL 964
            RKA WL  K L+   K+ +LE+   RKW++YWV LKG  LLF++   K  + +  + P   L  + S+VQ+VPE+ + ENVF +    G+ Y  QATSQT+ ENW+  +H++ A+ FA+K G E+   LL  + + L +K+  + K+ KMA LQL +  +   R+ I +QI  WE++LE  H   FR+RCY+A+++   +PNP+ LL   SRP+K AL +LG+ SV+SF + V +++   L     S  +R +N              K    SSLK  D    T  R       K +  R      DE    + S+  G  +        Y+   D     +  +P  ++ +++   C     +   Y + L  +++DN     ++Y IP     +    Y  +++ P   YDV LT         FG  +   +DER  ++  F+ D  P   A   G+   +E++ +NG+ +  ++      +E +    S+ L L + R  D K T  T+ S           + PPP +S    L ++ L+        D     + TT    S +D  +L + +  E ++      EQ+  + R     + N +   R       R    H      LRK I EL DTEK+YVK+L  L E YL PL+ E FL +DE E +  ++ E+ +FQ  F E L+  I   S+F+      QF+   LLF L
Sbjct:  508 RKAGWLFFKPLVTVQKERKLELVARRKWKQYWVTLKGCTLLFYETYGKN-SMDQSSAPRCALFAEDSIVQSVPEHPKKENVFCLSNSFGDVYLFQATSQTDLENWVTAVHSACASLFAKKHGKEDTLRLLKNQTKNLLQKIDMDSKMKKMAELQLSVVSDPKNRKAIENQIQQWEQNLEKFHMDLFRMRCYLASLQGGELPNPKSLLAAASRPSKLALGRLGILSVSSFHALVCSRDDSALRKRTLSLTQRGRN--------------KKGIFSSLKGLD----TLAR-------KGKEKRPSITQVDELLHIYGSTVDGVPRDNAWEIQTYVHFQDNHGVTVGIKPEHRVEDILTLACKMRQLEPSHYGLQLRKLVDDN-----VEYCIPAPYEYMQQQVYDEIEVFPLNVYDVQLTKTGSV--CDFGFAVTAQVDERQHLSRIFISDVLPDGLAYGEGLRKGNEIMTLNGEAVSDLDLK---QMEALFSEKSVGLTLIA-RPPDTKATLCTSWSDSDLFSRDQKSLLPPPNQS---QLLEEFLDNFKKNTANDFSNVPDITTGLKRSQTDG-TLDQVSHREKMEQTFRSAEQITALCRSFNDSQANGMEGPRENQDPPPRSLARHLSDADRLRKVIQELVDTEKSYVKDLSCLFELYLEPLQNETFLTQDEMESLFGSLPEMLEFQKVFLETLEDGISASSDFNTLETPSQFRK--LLFSL 1187

The following BLAST results are available for this feature:

BLAST of TCONS_00014480-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00014480-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
TIAM2	2.940e-78	30.01	T-lymphoma invasion and metastasis-inducing protei...	[more]

You are here

TCONS_00014480-protein (polypeptide) - C. hemisphaerica