TCONS_00013463-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00013463-protein
Unique NameTCONS_00013463-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1051

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00013463-protein ID=TCONS_00013463-protein|Name=TCONS_00013463-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1051bp
MHKMTTFGLLTAIIFLLQCLKMTLCEAQCPTGCICISQNNAIPTSYCDGQ
GYRNVPQNINPKTEILSLTQNNFYQLKKKDFRNLQKLTRLSLKMNGIQRI
ADDAFLHLNKLKYLNLGKNNLKSISIKVFEHLPSLEELYLNDNQLEGLPS
ELYNVLPNLRKLHLQNNNLKDNKFIANLKKLEYLDLSKNKLKEIRARMFQ
NSPNLRSVRLEENQIEAIETDSFKTLSQLTEVLLNDNEIYTLDKKLFANK
SQLKKVTLHGNPLRCDCNLHWIYNVLMSAPKMFDHKEEMRCHSPSTLVGK
PIVELYEDSFGCELSVWGTWEQWSTCNKPCGGGQRMRKRDCLSSSSSGDD
GGNCKGDGMEREKCNAKECTVKGLFTTWSTWSNCPPGVYAERLRTRKCFN
PFSDSSVKVTCRGKVVEKELCYGKPVHGGWSQWSGWSDCSQLCKLGTATR
TRTCTNPMPQFNGKLCDGLTIEKQTKVCLAALCPPKTEWGEWSEFSKCTA
TCGEGLQTRRRQCLNEFNQPIEIQKICPGKDTESKKCVRSKCIINGAWSP
WLQWSACDSMSCKRSRIRTCVRHDKRNIENSHCEGESVQQEYCPRSQCSI
NSIWSPWSQWSDCSKKCGRGVRIRSRPCPGEKSHPSVTCGDQRSESEPCN
VHSCNTQVWSEWSEWSKCPNPTTNKQVRKRVCLGAGQNRCSGRSKERRQC
LREKVVVDDGKVVKTKENECQPREQIENGRVENVPTENGLFVKYKCDAFY
RLKGNDGSDNATCVKGKGWNRNYIPYCIPTCGKPVHKSYSHWYSRARLHG
GEITIPHSWPWQVLLEVKTKDIGWKLSCGGSLINDRWVVTAGHCLFDKPP
ELRQFKPEEIKVYLGVHNVIDRQRSKHVQMSYAKLVVPNLKFDHALLDND
IGLIELATPAKLNDRILPVCLPSRRQRKLVAVGNVGTVVGWGVTRSQRAS
EELKELRLPVMDYNECVKAYDKSYNLTKSMFCAGKNTSEDTCKGDSGGGY
LFRDARKKKWTLQGVVSWGGPQCGKAEKPSVYTKVSLFTAWIRAVIRDRK
V
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007524XLOC_007524Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00013463TCONS_00013463Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001314Peptidase_S1A
IPR000436Sushi_SCR_CCP_dom
IPR001254Trypsin_dom
IPR003591Leu-rich_rpt_typical-subtyp
IPR000884TSP1_rpt
IPR000483Cys-rich_flank_reg_C
IPR032675L_dom-like
IPR001611Leu-rich_rpt
IPR018114TRYPSIN_HIS
IPR009003Peptidase_S1_PA
Vocabulary: Molecular Function
TermDefinition
GO:0004252serine-type endopeptidase activity
GO:0005515protein binding
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0005515 protein binding
molecular_function GO:0004252 serine-type endopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001314Peptidase S1A, chymotrypsin familyPRINTSPR00722CHYMOTRYPSINcoord: 896..910
score: 39.42
coord: 989..1001
score: 52.94
coord: 829..844
score: 58.32
NoneNo IPR availablePRINTSPR01705TSP1REPEATcoord: 428..441
score: 53.32
coord: 446..457
score: 46.43
coord: 689..700
score: 35.64
NoneNo IPR availableSMARTSM00365LRR_sd22_2coord: 178..204
e-value: 56.0
score: 9.5
coord: 132..150
e-value: 70.0
score: 8.7
coord: 84..105
e-value: 90.0
score: 7.8
NoneNo IPR availableGENE3D2.40.10.10coord: 835..918
e-value: 1.5E-22
score: 79.2
NoneNo IPR availableGENE3D2.30.90.10coord: 374..421
e-value: 0.0018
score: 18.3
coord: 658..700
e-value: 8.6E-5
score: 22.5
NoneNo IPR availableGENE3D2.10.70.10coord: 710..781
e-value: 4.0E-7
score: 29.9
NoneNo IPR availableGENE3D2.40.10.10coord: 798..834
e-value: 3.3E-16
score: 58.6
NoneNo IPR availableGENE3D2.40.10.10coord: 919..1049
e-value: 1.1E-39
score: 135.3
IPR000436Sushi/SCR/CCP domainSMARTSM00032CCP_2coord: 720..777
e-value: 6.3E-5
score: 32.4
IPR000436Sushi/SCR/CCP domainPROSITEPS50923SUSHIcoord: 718..779
score: 8.789
IPR000436Sushi/SCR/CCP domainSUPERFAMILY57535Complement control module/SCR domaincoord: 719..783
IPR001254Serine proteases, trypsin domainSMARTSM00020trypsin_2coord: 797..1042
e-value: 2.1E-72
score: 256.5
IPR001254Serine proteases, trypsin domainPFAMPF00089Trypsincoord: 800..1042
e-value: 7.7E-58
score: 195.8
IPR001254Serine proteases, trypsin domainPROSITEPS50240TRYPSIN_DOMcoord: 798..1047
score: 33.4
IPR001254Serine proteases, trypsin domainCDDcd00190Tryp_SPccoord: 800..1045
e-value: 1.17039E-72
score: 239.871
IPR003591Leucine-rich repeat, typical subtypeSMARTSM00369LRR_typ_2coord: 132..155
e-value: 0.0031
score: 26.7
coord: 84..107
e-value: 1.6
score: 17.8
coord: 156..177
e-value: 220.0
score: 2.3
coord: 108..131
e-value: 0.62
score: 19.1
coord: 226..249
e-value: 2.6
score: 17.0
coord: 178..201
e-value: 0.0041
score: 26.3
coord: 203..225
e-value: 58.0
score: 7.0
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 604..655
e-value: 2.6E-9
score: 47.0
coord: 659..706
e-value: 0.077
score: 19.2
coord: 548..599
e-value: 0.05
score: 20.8
coord: 430..484
e-value: 2.5E-12
score: 57.0
coord: 489..543
e-value: 2.5E-10
score: 50.3
coord: 317..370
e-value: 5.0E-10
score: 49.3
coord: 375..427
e-value: 7.1
score: 1.7
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 377..422
e-value: 0.13
score: 12.4
coord: 605..654
e-value: 7.8E-10
score: 38.7
coord: 431..483
e-value: 1.6E-8
score: 34.6
coord: 549..598
e-value: 0.16
score: 12.1
coord: 660..702
e-value: 0.047
score: 13.8
coord: 319..369
e-value: 3.2E-9
score: 36.8
coord: 490..542
e-value: 1.0E-8
score: 35.2
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 485..542
e-value: 1.0E-11
score: 44.5
coord: 544..598
e-value: 3.6E-6
score: 26.7
coord: 316..369
e-value: 1.3E-10
score: 40.9
coord: 426..483
e-value: 1.3E-13
score: 50.5
coord: 600..654
e-value: 5.1E-11
score: 42.2
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 427..484
score: 11.958
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 601..655
score: 12.234
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 545..599
score: 9.744
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 486..543
score: 11.468
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 656..704
score: 8.971
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 314..370
score: 12.193
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 601..651
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 658..701
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 542..598
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 425..483
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 483..542
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 316..369
IPR000483Cysteine-rich flanking region, C-terminalSMARTSM00082lrrct1coord: 261..313
e-value: 4.3E-10
score: 49.5
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 165..315
e-value: 1.1E-31
score: 109.2
IPR032675Leucine-rich repeat domain, L domain-likeGENE3D3.80.10.10coord: 18..164
e-value: 1.2E-30
score: 105.6
IPR032675Leucine-rich repeat domain, L domain-likeSUPERFAMILY52058L domain-likecoord: 33..312
IPR001611Leucine-rich repeatPFAMPF13855LRR_8coord: 86..145
e-value: 9.5E-16
score: 57.2
coord: 157..215
e-value: 1.4E-10
score: 40.7
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 228..249
score: 4.917
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 110..131
score: 7.088
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 204..225
score: 6.126
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 134..155
score: 7.027
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 158..179
score: 7.635
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 86..107
score: 6.819
IPR001611Leucine-rich repeatPROSITEPS51450LRRcoord: 180..201
score: 7.389
IPR018114Serine proteases, trypsin family, histidine active sitePROSITEPS00134TRYPSIN_HIScoord: 839..844
IPR009003Peptidase S1, PA clanSUPERFAMILY50494Trypsin-like serine proteasescoord: 770..1047

Blast
[Close]
BLAST of TCONS_00013463-protein vs. Swiss-Prot (Human)
Match: HMCN1 (Hemicentin-1 OS=Homo sapiens GN=HMCN1 PE=1 SV=2)

HSP 1 Score: 193.356 bits (490), Expect = 9.716e-50
Identity = 124/369 (33.60%), Postives = 158/369 (42.82%), Query Frame = 0 
Query:  295 STLVGKPIVELYEDSFGCELSVWGTWEQWSTCNKPCGGGQRMRKRDCLSSSSSGDDGGNCKGDGMEREKCNAKECTVKGLFTTWSTWSNCPPGV-YAERLRTRKCFNPFSDSSVKVTCRGKVVEKELCYGKP--VHGGWSQWSGWSDCSQLCKLGTATRTRTCTNPMPQFNGKLCDGLTIEKQTKVCLAALCPPKTEWGEWSEFSKCTATCGEGLQTRRRQCLNEFNQPIEIQKICPGKDTESKKCVRSKCIINGAWSPWLQWSACDSMSC---KRSRIRTCVRHDKRNIENSHCEGESVQQEYCPRSQCSINSIWSPWSQWSDCSKKCGRGVRIRSRPCPGEKSHPSVTCGDQRSESEPCNVHSCNTQ 657
            S LV  P++      F         W  W  C+  CG G + R R C +     + G  C+G  +E   C  K C V G ++ WS W  C        + RTR C NP      +  C G  VE  +C  +P  VHG WS W  W  CS+ C  GT TR R C NP P F G  CDG   E Q +VC    CP   +W  W+ +S C+ +CG G + R R C +    P    + C G D +S  C    C  +G WSPW  W  C S +C   +  R RTC      N     C G   Q + C    C ++  W  W  WS CS  CG G + R R C     HP    G +    +   V  CN Q
Sbjct: 4517 SVLVRVPVIVQVHGGFS-------QWSAWRACSVTCGKGIQKRSRLC-NQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGR-PCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGA--ETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPV--PQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTC-SRTCNGGQMRRYRTCDNPPPSN-GGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC----DHPVPVKGGRPCPGDTTQVTRCNVQ 4866

HSP 2 Score: 174.866 bits (442), Expect = 5.997e-44
Identity = 118/346 (34.10%), Postives = 157/346 (45.38%), Query Frame = 0 
Query:  371 VKGLFTTWSTWS----NCPPGVYAERLRTRKCFNPFSDSSVKVTCRGKVVEKELCYGKP--VHGGWSQWSGWSDCSQLCKLGTATRTRTCTNPMPQFNGKLCDGLTIEKQTKVCLAALCPPKTEWGEWSEFSKCTATCGEGLQTRRRQCLNEFNQPIEIQKICPGKDTESKKCVRSKCIINGAWSPWLQWSACDSMSC---KRSRIRTCVRHDKRNIENSHCEGESVQQEYCPRSQCSINSIWSPWSQWSDCSKKCGRGVRIRSRPCPGEK-SHPSVTCGDQRSESEPCNVHSCNTQ-VWSEWSEWSKCPNP-TTNKQVRKRVCLGA----GQNRCSGRSKERRQC 700
            V G F+ WS W      C  G+   + R+R C  P   +  K  C+G  +E   C  KP  V G WS+WS W +C++ C  G  TRTRTC NP  Q  G+ C+G  +E    +C    CP    W  W  +  C+ +CG+G QTR R C N    P      C G +T+ + C    C I+G W+ W  WSAC S+SC    R R R C            CEG  VQ ++C    C  +  WSPWS W  CS+ C  G   R R C     S+    CG   S+ + CN   C     W  W  WS+C       ++ RKR+C       G   C G + +  +C
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGI---QKRSRLCNQPLPANGGK-PCQGSDLEMRNCQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVE--IIMCNIRPCPVHGAWSAWQPWGTCSESCGKGTQTRARLCNNP--PPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSAC-SVSCGGGARQRTRGC-SDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRC 4863

HSP 3 Score: 157.918 bits (398), Expect = 8.531e-39
Identity = 105/297 (35.35%), Postives = 135/297 (45.45%), Query Frame = 0 
Query:  426 VHGGWSQWSGWSDCSQLCKLGTATRTRTCTNPMPQFNGKLCDGLTIEKQTKVCLAALCPPKTEWGEWSEFSKCTATCGEGLQTRRRQCLNEFNQPIEIQKICPGKDTESKKCVRSKCIINGAWSPWLQWSACDSMSCKR---SRIRTCVRHDKRNIENSHCEGESVQQEYCPRSQCSINSIWSPWSQWSDCSKKCGRGVRIRSRPCPGEKSHPSVTCGDQRSE-----SEPCNVHSCNTQV-WSEWSEWSKCPNPTTNKQVRK-RVCLGA----GQNRCSGRSKERRQCLREKVVVD 708
            VHGG+SQWS W  CS  C  G   R+R C  P+P   GK C G  +E +   C    CP    W EWS + +CT +CG G QTR R C N   Q     + C G   E   C    C ++GAWS W  W  C S SC +   +R R C  +       S+C+G   Q + C    C I+  W+ W+ WS CS  CG G R R+R C    S P    G ++ E     S+ CN   C T   WS WS W  C       Q+R+ R C       G   C G   + ++C  +   VD
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRN--CQNKPCPVDGSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQ--HGGRPCEGNAVEIIMCNIRPCPVHGAWSAWQPWGTC-SESCGKGTQTRARLC-NNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGC----SDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVD 4814

HSP 4 Score: 150.599 bits (379), Expect = 1.563e-36
Identity = 80/229 (34.93%), Postives = 114/229 (49.78%), Query Frame = 0 
Query:  317 WGTWEQWSTCNKPCGGGQRMRKRDCLSSSSSGDDGGNCKGDGMEREKCNAKECTVKGLFTTWSTWSNCPPGVYA-ERLRTRKCFNPFSDSSVKVTCRGKVVEKELCYGKP--VHGGWSQWSGWSDCSQLCKLGTATRTRTCTNPMPQFNGKLCDGLTIEKQTKVCLAALCPPKTEWGEWSEFSKCTATCGEGLQTRRRQCLNEFNQPIEIQKICPGKDTESKKCVRSKC 542
            W  W+ W TC++ CG G + R R C ++      G  C G   + + CN + C + G + TW++WS C        R RTR C +P      +  C G  V+ + C   P   HG WS WSGW  CS+ C  G   R RTC NP P   G+ C G   + Q + C   +CP    WG W  +S+C+A+CG G +TR+R C  +   P++  + CPG  T+  +C    C
Sbjct: 4646 WSAWQPWGTCSESCGKGTQTRARLC-NNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGR-KCEGSDVQSDFCNSDPCPTHGNWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGP--DSQIQRCNTDMCPVDGSWGSWHSWSQCSASCGGGEKTRKRLC--DHPVPVKGGRPCPGDTTQVTRCNVQAC 4868
The following BLAST results are available for this feature:
BLAST of TCONS_00013463-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HMCN19.716e-5033.60Hemicentin-1 OS=Homo sapiens GN=HMCN1 PE=1 SV=2[more]
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