TCONS_00011512-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00011512-protein
Unique Name	TCONS_00011512-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	873

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00011512-protein ID=TCONS_00011512-protein|Name=TCONS_00011512-protein|organism=Clytia hemisphaerica|type=polypeptide|length=873bp
MGDRRFSEQLTGKDAPDLVYKLMLAEVKILQEMESYTEKRAALDYEYGEK
LAKLHEKIKIGESDPHTEGSQVEKAWRTYLTESENKAITIMNNAKNLGGS
TQQSIKNLRARKKDTADKFQQQKLKIEAEYLRSNGEADRLQASYQVALKE
AGKLKDKLDDLYKKNKSQRDWQKGKERFDDASRKLHMNHNLYFLSIKLLN
IHQNHKVYELNPHILDTAQEIETKYLKVWKDIFLEIVDNSSWSREEFMTS
ENELRQTIDLVSPATEFKHFIAVNKKSKKPLFPHLFDTKLIEDSNATSGL
TDDMLAVNDLTHDQLINKKMDLEQDNSIYLDDLVKKKSQLEEENKKLRKM
ANEDNNNTQYSTILQYSLCQQKLIELKETECKFACTKVQFDSIEDALSRE
SNPKQPYIDLSPPRPSSSKSNTSLNSTAAGVSNERSDPPERKARSSTLPR
TLAKNFRRKSLTSPPKVPVKPRPPSPSVSSDTEGDYDDPESSGGGPKTLA
QCDYFHGSVDRSTVTRLLKCDGDFIVREKSGSSADYVLSVLWRGQTKHFI
LKADDGMYKLEGESFPSIPQLVDHHHQKRSIVQATTGVILVNPIRIAFKP
GDGYTYKQTDVRLDQTLGSGHFGEVFKGYLIPLKMPVAIKSCKPKDDVAN
QKQKFIEEAEIMKPCQHPNLIKLIGVCIDRDPYYILLELCEKGDLLNFLR
KESVRLNPQQRIKMANDVANGMSFLERNKIIHRDLAARNCLVKLDMTVKI
CDFGMSREEEEEGLYTMKETKVIPFKWTAPEVWRYNRYTSKSDVWSFGVT
LWEIFSGGKQPYPDKKNHEAKRYVEEGNRLDAPSGTPPSVDELMKLCWLE
LEQDRPNFQEICRSLKDMRRTKR

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_006443	XLOC_006443	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00011512	TCONS_00011512	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001245	Ser-Thr/Tyr_kinase_cat_dom
IPR000980	SH2
IPR001060	FCH_dom
IPR020635	Tyr_kinase_cat_dom
IPR016250	Tyr-prot_kinase_Fes/Fps
IPR017441	Protein_kinase_ATP_BS
IPR008266	Tyr_kinase_AS
IPR000719	Prot_kinase_dom
IPR031160	F_BAR
IPR011009	Kinase-like_dom
IPR027267	AH/BAR-dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0004672	protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005524	ATP binding

Vocabulary: **Biological Process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0018108	peptidyl-tyrosine phosphorylation

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0018108	peptidyl-tyrosine phosphorylation
biological_process	GO:0006468	protein phosphorylation
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004672	protein kinase activity
molecular_function	GO:0004713	protein tyrosine kinase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 105..125
None	No IPR available	COILS	Coil	Coil	coord: 137..164
None	No IPR available	COILS	Coil	Coil	coord: 330..357
None	No IPR available	GENE3D	1.10.510.10		coord: 690..873 e-value: 1.5E-52 score: 177.9
None	No IPR available	GENE3D	3.30.200.20		coord: 601..689 e-value: 2.0E-25 score: 88.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 397..499
None	No IPR available	CDD	cd00192	PTKc	coord: 617..866 e-value: 3.60464E-117 score: 358.39
None	No IPR available	CDD	cd10361	SH2_Fps_family	coord: 497..579 e-value: 5.71426E-21 score: 88.3534
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PRINTS	PR00109	TYRKINASE	coord: 724..742 score: 62.78 coord: 687..700 score: 48.23 coord: 792..814 score: 62.44 coord: 836..858 score: 36.7 coord: 773..783 score: 55.48
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain	PFAM	PF07714	Pkinase_Tyr	coord: 612..865 e-value: 1.1E-91 score: 306.7
IPR000980	SH2 domain	SMART	SM00252	SH2_5	coord: 502..581 e-value: 7.0E-22 score: 88.7
IPR000980	SH2 domain	PFAM	PF00017	SH2	coord: 504..575 e-value: 5.2E-14 score: 52.0
IPR000980	SH2 domain	GENE3D	3.30.505.10		coord: 489..597 e-value: 3.7E-23 score: 80.9
IPR000980	SH2 domain	PROSITE	PS50001	SH2	coord: 504..594 score: 16.158
IPR000980	SH2 domain	SUPERFAMILY	55550	SH2 domain	coord: 496..625
IPR001060	FCH domain	SMART	SM00055	fch_2	coord: 4..97 e-value: 4.2E-7 score: 39.6
IPR001060	FCH domain	PFAM	PF00611	FCH	coord: 18..87 e-value: 1.6E-9 score: 37.8
IPR020635	Tyrosine-protein kinase, catalytic domain	SMART	SM00219	tyrkin_6	coord: 611..865 e-value: 1.2E-123 score: 426.7
IPR016250	Tyrosine-protein kinase, Fes/Fps type	PIRSF	PIRSF000632	TyrPK_fps	coord: 4..873 e-value: 1.3E-184 score: 613.4
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 617..640
IPR008266	Tyrosine-protein kinase, active site	PROSITE	PS00109	PROTEIN_KINASE_TYR	coord: 730..742
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 611..873 score: 39.509
IPR031160	F-BAR domain	PROSITE	PS51741	F_BAR	coord: 4..266 score: 22.385
IPR011009	Protein kinase-like domain	SUPERFAMILY	56112	Protein kinase-like (PK-like)	coord: 609..867
IPR027267	Arfaptin homology (AH) domain/BAR domain	SUPERFAMILY	103657	BAR/IMD domain-like	coord: 6..287

Blast

[Close]

BLAST of TCONS_00011512-protein vs. Swiss-Prot (Human)
Match: FER (Tyrosine-protein kinase Fer OS=Homo sapiens GN=FER PE=1 SV=2)

HSP 1 Score: 451.44 bits (1160), Expect = 4.770e-146
Identity = 295/869 (33.95%), Postives = 461/869 (53.05%), Query Frame = 0

Query:   13 KDAPDLVYKLMLAEVKILQEMESYTEKRAALDYEYGEKLAKLHEKIKIGESDPHTEGSQVEKAWRTYLTESENKAITIMNNAKNLGGSTQQSIKNLRARKKDTADKFQQQKLKIEAEYLR-SNGEADRLQASYQVALKEAGKLKDKLDDLYKKNKSQRDWQKGKERFDDASRKLHMNHNLYFLSIKLLNIHQNHKVYELN-PHILDTAQEIETKYLKVWKDIFLEIVDNSSWSREEFMTSENELRQTIDLVSPATEFKHFIAVNKKSKKPLFPHLFDTKLIEDSNATSGLTDDMLAVNDLTHD--QLINKKM--DLEQDNSIYLDDLVKKKSQLEEENKKLRKMANEDNNNTQYSTILQYSLCQ-QKLIELKETECKFACTKVQFDSIEDALS---RESNPKQPYIDLSPPRPSSSKSNTSLNSTAAGVSNERSDPPERKARSSTLPRTLAKNFRRKSLTSPPKVPVKPRPPSPSVSSDTEGDYDDPESSGGGPKTLAQCDYFHGSVDRSTVTRLLKCDGDFIVREKSGSSADYVLSVLWRGQTKHFILKADDGMYKLEGESFPSIPQLVDHHHQKRSIVQATTGVILVNPIRIAFKPGD-GYTYKQTDVRLDQTLGSGHFGEVFKGYLIPLKMPVAIKSCKPKDDVANQKQKFIEEAEIMKPCQHPNLIKLIGVCIDRDPYYILLELCEKGDLLNFLRKESVRLNPQQRIKMANDVANGMSFLERNKIIHRDLAARNCLVKLDMTVKICDFGMSREEEEEGLYTMKETKVIPFKWTAPEVWRYNRYTSKSDVWSFGVTLWEIFSGGKQPYPDKKNHEAKRYVEEGNRLDAPSGTPPSVDELMKLCWLELEQDRPNFQEICRSLKDMRR 870
            K++ + V KL   E+++L+ ++ +   R   D EY   L  L  ++    +      S V K+W   + ++E  +  +  +A++L       +  +   K+     +     +IEAE ++ +  E ++L+ SY+  +KE    K+K  +   K K   + +K KER+D A+ KLHM HN Y L++K   +HQN + Y++  P +LD+ Q+++ + +K  K IF E    +S   EE +    E++ +++ + P+TE+ +FI V++ +        FDT L+E++     L  + +  N+LT +  Q++ K +  +L Q   + L+         EE   +L K   E +   +  + +   L Q Q L ELK++  +  CT+ +F + ++ L    +E++ K+P     PP  +  +   S+ S             ERK R S           R S+          R P  ++ S    D           K LA+ D++HG++ R     LLK  GDF+VRE  G   +YVLSV   GQ +HFI++  D MY+ EG  F +IPQL+DHH+  + ++   +GV+L+NPI     P D  +     DV L + LG G+FGEV+KG L   K  VA+K+CK +D     K KF++EA+I+K   HPN++KLIGVC  R P YI++EL   GD L FLR++   L  +Q +K + D A GM +LE    IHRDLAARNCLV  +  +KI DFGMSR +E+ G+Y+    K IP KWTAPE   Y RY+S+SDVWSFG+ LWE FS G  PYP   N +A+  VE G R+ AP   P  + ++M  CW    ++RP F E+ + L  ++R
Sbjct:    8 KNSHEAVLKLQDWELRLLETVKKFMALRIKSDKEYASTLQNLCNQVDKESTVQMNYVSNVSKSWLLMIQQTEQLSRIMKTHAEDLNSGPLHRLTMMIKDKQQVKKSYIGVHQQIEAEMIKVTKTELEKLKCSYRQLIKEMNSAKEKYKEALAKGK---ETEKAKERYDKATMKLHMLHNQYVLALKGAQLHQN-QYYDITLPLLLDSLQKMQEEMIKALKGIFDEYSQITSLVTEEIVNVHKEIQMSVEQIDPSTEYNNFIDVHRTTAAKEQEIEFDTSLLEENE---NLQANEIMWNNLTAESLQVMLKTLAEELMQTQQMLLNK--------EEAVLELEKRIEESSETCEKKSDIVLLLSQKQALEELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKEP-----PPVVNYEEDARSVTSM------------ERKERLSKFESI------RHSIAGI------IRSPKSALGSSALSDMISI-----SEKPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPI-----PKDKKWILSHEDVILGELLGKGNFGEVYKGTLKD-KTSVAVKTCK-EDLPQELKIKFLQEAKILKQYDHPNIVKLIGVCTQRQPVYIIMELVSGGDFLTFLRRKKDELKLKQLVKFSLDAAAGMLYLESKNCIHRDLAARNCLVGENNVLKISDFGMSR-QEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFGILLWETFSLGVCPYPGMTNQQAREQVERGYRMSAPQHCPEDISKIMMKCWDYKPENRPKFSELQKELTIIKR 819

The following BLAST results are available for this feature:

BLAST of TCONS_00011512-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00011512-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
FER	4.770e-146	33.95	Tyrosine-protein kinase Fer OS=Homo sapiens GN=FER...	[more]

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TCONS_00011512-protein (polypeptide) - C. hemisphaerica