TCONS_00011271-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00011271-protein vs. Swiss-Prot (Human)
Match: MDR1 (Multidrug resistance protein 1 OS=Homo sapiens GN=ABCB1 PE=1 SV=3)

HSP 1 Score: 1017.68 bits (2630), Expect = 0.000e+0
Identity = 539/1170 (46.07%), Postives = 762/1170 (65.13%), Query Frame = 0

Query:   96 VSVSQLFRYASTTDWVFMFFASISACINGVLQPVSFIIFGELINDFVD-----------------EDSGKTIDLNKEMEKFGIYYVYIGLGAIVFGYFQNMLWLRASINQAFRIRTLAFESILKQDIGFFDTNDAGELSSRLADGVTKVQNGIGDKIGSLQHAIAMLVGGIIIGFIYGWKLTLVIIAMSPLLFIGAFATGKVIGMITSQEQTSYAKAGSIAEEVLSSIRTVVAFGSERKEIDRYRVNLKDAEKAGIRKGL----STGFAFALFNSTLFGCMALGFWYGGTLIGDGEINAGDLLIVFFSVMIGANQFGQVGPNIEAFSSARGAAYTIFKLIERKPVIDSLTDAGEKT-KIEGDIKFVDCQFSYPSRPDIKILRGLNLNIKPGTTCALVGESGCGKSTTVKLIQRFYDAAGGRVQIDGVDIKRINVKHLRKHIGVVSQEPVLFDASIKKNILMGHPEATEDMVIEAAKNANAHDFISKLPQGYDTNVGEGGAQLSGGQKQRIAIARALVRDPKILLLDEATSALDTGSEAIVQAALDKASLGRTTVIIAHRLSTVKNADSIAVVSAGQVSELGSHKELMDKRGEYFKLVMLQNFEEQEEEELNSELGSVISESEREEIIARKMMRSLSQLSNTGSETDQQLVKELIDREITHRKSIRRVKSTVGTQKQVSKLDRQLSQTKEVKEEELPEDEPVQIPPIS--RILKLNAKEWPYIVTGIFFSAIAGTMPVLFAIILAEILQSFAE-NDPQEMEKKMEFWAIMFMVIGLVIGVAFFIAQYLFAKAGEALTTRLREMAFTSLLRQEIGYFDLPQHSTGALSARLSADASAVQGATSTRLNTLTQVVVTGLSSLIVAFAYSWQLSLLVLAFVPFIAMFGAIQTSLNTSFAGDAQKKLSQAGAISTEAIMQIRTVASLGKEDFFFDKYKSLLMGPTQGSRKGAHIYGIAYGFSIGVMLFSNGACFRLGGYLAERDGLSLSSIVKVIIGIQFGAMTAGQVASFAPDYVKAKTAAGRILALFDRKPAIDSYSTEGI-KNEIKGDITFTDVEFTYPTRQNVPILQKLNIKIPRGRTVAFVGASGCGKSTSVSLLERFYEVAGGEVLIDDIPIKDYNIRALRSQIGIVQQEPVLFDRSIRDNILYGIEDPSQITQEQIEEACRNSNIHHVI 1239
            VSV  +FRY++  D ++M   +++A I+G   P+  ++FGE+ + F +                  D+G  ++L ++M ++  YY  IG G +V  Y Q   W  A+  Q  +IR   F +I++Q+IG+FD +D GEL++RL D V+K+  GIGDKIG    ++A    G I+GF  GWKLTLVI+A+SP+L + A    K++   T +E  +YAKAG++AEEVL++IRTV+AFG ++KE++RY  NL++A++ GI+K +    S G AF L    ++   AL FWYG TL+  GE + G +L VFFSV+IGA   GQ  P+IEAF++ARGAAY IFK+I+ KP IDS + +G K   I+G+++F +  FSYPSR ++KIL+GLNL ++ G T ALVG SGCGKSTTV+L+QR YD   G V +DG DI+ INV+ LR+ IGVVSQEPVLF  +I +NI  G    T D + +A K ANA+DFI KLP  +DT VGE GAQLSGGQKQRIAIARALVR+PKILLLDEATSALDT SEA+VQ ALDKA  GRTT++IAHRLSTV+NAD IA    G + E G+H ELM ++G YFKLV +Q    +       EL +   ES+ E          +  L  + +++   L+     R+ + R+S+R      G+Q Q    DR+LS TKE  +E         IPP+S  RI+KLN  EWPY V G+F + I G +   FAII ++I+  F   +DP+   +    ++++F+ +G++  + FF+  + F KAGE LT RLR M F S+LRQ++ +FD P+++TGAL+ RL+ DA+ V+GA  +RL  +TQ +    + +I++F Y WQL+LL+LA VP IA+ G ++  + +  A   +K+L  +G I+TEAI   RTV SL +E  F   Y   L  P + S + AHI+GI + F+  +M FS   CFR G YL     +S   ++ V   + FGAM  GQV+SFAPDY KAK +A  I+ + ++ P IDSYSTEG+  N ++G++TF +V F YPTR ++P+LQ L++++ +G+T+A VG+SGCGKST V LLERFY+   G+VL+D   IK  N++ LR+ +GIV QEP+LFD SI +NI YG ++   ++QE+I  A + +NIH  I
Sbjct:   34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLL----IYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGNLEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNE------VELENAADESKSE----------IDALEMSSNDSRSSLI-----RKRSTRRSVR------GSQAQ----DRKLS-TKEALDES--------IPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYG-DNSRVVSQEEIVRAAKEANIHAFI 1158          

HSP 2 Score: 446.432 bits (1147), Expect = 8.644e-136
Identity = 240/571 (42.03%), Postives = 353/571 (61.82%), Query Frame = 0

Query:  108 TDWVFMFFASISACINGVLQPVSFIIFGELINDFVDEDSGKTIDLNKEMEKFGIYYVYIGLGAIVFGYFQNMLWLRASINQAFRIRTLAFESILKQDIGFFD--TNDAGELSSRLADGVTKVQNGIGDKIGSLQHAIAMLVGGIIIGFIYGWKLTLVIIAMSPLLFIGAFATGKVIGMITSQEQTSYAKAGSIAEEVLSSIRTVVAFGSERKEIDRYRVNLKDAEKAGIRKGLSTGFAFALFNSTLFGCMALGFWYGGTLIGDGEINAGDLLIVFFSVMIGANQFGQVGPNIEAFSSARGAAYTIFKLIERKPVIDSLTDAG-EKTKIEGDIKFVDCQFSYPSRPDIKILRGLNLNIKPGTTCALVGESGCGKSTTVKLIQRFYDAAGGRVQIDGVDIKRINVKHLRKHIGVVSQEPVLFDASIKKNILMGHPE--ATEDMVIEAAKNANAHDFISKLPQGYDTNVGEGGAQLSGGQKQRIAIARALVRDPKILLLDEATSALDTGSEAIVQAALDKASLGRTTVIIAHRLSTVKNADSIAVVSAGQVSELGSHKELMDKRGEYFKLVMLQ 673
            T+W +       A ING LQP   IIF ++I  F   D  +T   N  +  F + ++ +G+ + +  + Q   + +A      R+R + F S+L+QD+ +FD   N  G L++RLA+   +V+  IG ++  +   IA L  GIII FIYGW+LTL+++A+ P++ I      K++     +++     +G IA E + + RTVV+   E+K    Y  +L+   +  +RK    G  F+   + ++   A  F +G  L+    ++  D+L+VF +V+ GA   GQV      ++ A+ +A  I  +IE+ P+IDS +  G     +EG++ F +  F+YP+RPDI +L+GL+L +K G T ALVG SGCGKST V+L++RFYD   G+V +DG +IKR+NV+ LR H+G+VSQEP+LFD SI +NI  G      +++ ++ AAK AN H FI  LP  Y T VG+ G QLSGGQKQRIAIARALVR P ILLLDEATSALDT SE +VQ ALDKA  GRT ++IAHRLST++NAD I V   G+V E G+H++L+ ++G YF +V +Q
Sbjct:  706 TEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQNSNL--FSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGCFRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGNVTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1274