TCONS_00010072-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00010072-protein
Unique NameTCONS_00010072-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length522

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00010072-protein ID=TCONS_00010072-protein|Name=TCONS_00010072-protein|organism=Clytia hemisphaerica|type=polypeptide|length=522bp
GKKKKKMNTIVGITFLCTLIRGIASKSDAFTSIHDIKQILHKERVLTRYL
NLAIEAEKERLGELEGMRDSMKMKLLNLNISSMDDYVGNPLNALHTIRRF
TADWNEITNTLNTTRVQEFFNEWDRNVKLPTLEDQKGAVSGILRLQNFYK
INTRNVSRGFLSSTNPISKTEEIGVGLMWAMGYEAFKQKEWFLMKEWLDL
ALERIGDLEQSDGCKRSWIVDFLSYAEFQLGDYERSLDLAYQCLEYSPDD
QKHHNNIEQCKKKISKGRKKSSTKPVEQLRYQLCRGEGMRKPTIDEELQM
VCWYKNDQPILRYKPQKVERLWARPEIVMFRELLNDEQTGTLIDLSLQKL
VRAGLNGQDVTSEKYTNSRVAKHAWLSMKESPIIRNMGKRAQAMTNLNMK
YAEHLQIANYGIGGHYDAHYDYQTGENVFPDLKTGNRIATLMYYLSDVEA
GGGTAFTFGKTTVYPSKGDAVFWWNLKQNGKVDESSKHAGCPVLMGQKWI
ANWWIHEYGQEFRRPCPLDKTL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_005649XLOC_005649Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00010072TCONS_00010072Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006620Pro_4_hyd_alph
IPR005123Oxoglu/Fe-dep_dioxygenase
IPR011990TPR-like_helical_dom
IPR013547Pro_4_hyd_alph_N
Vocabulary: Molecular Function
TermDefinition
GO:0005506iron ion binding
GO:0031418L-ascorbic acid binding
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016491oxidoreductase activity
GO:0005515protein binding
GO:0004656procollagen-proline 4-dioxygenase activity
GO:0016702oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: Cellular Component
TermDefinition
GO:0005783endoplasmic reticulum
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
cellular_component GO:0005783 endoplasmic reticulum
molecular_function GO:0005506 iron ion binding
molecular_function GO:0031418 L-ascorbic acid binding
molecular_function GO:0016491 oxidoreductase activity
molecular_function GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
molecular_function GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
molecular_function GO:0004656 procollagen-proline 4-dioxygenase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 54..74
NoneNo IPR availableGENE3D2.60.120.620coord: 315..513
e-value: 1.5E-35
score: 122.3
IPR006620Prolyl 4-hydroxylase, alpha subunitSMARTSM00702p4hccoord: 325..506
e-value: 2.6E-48
score: 176.5
IPR005123Oxoglutarate/iron-dependent dioxygenasePFAMPF136402OG-FeII_Oxy_3coord: 405..506
e-value: 1.6E-16
score: 60.9
IPR005123Oxoglutarate/iron-dependent dioxygenasePROSITEPS51471FE2OG_OXYcoord: 401..507
score: 11.153
IPR011990Tetratricopeptide-like helical domainGENE3D1.25.40.10coord: 132..265
e-value: 3.2E-7
score: 29.8
IPR011990Tetratricopeptide-like helical domainSUPERFAMILY48452TPR-likecoord: 222..266
IPR013547Prolyl 4-hydroxylase alpha-subunit, N-terminalPFAMPF08336P4Ha_Ncoord: 32..161
e-value: 1.1E-26
score: 93.4

Blast
BLAST of TCONS_00010072-protein vs. Swiss-Prot (Human)
Match: P4HA2 (Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens GN=P4HA2 PE=1 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 4.373e-91
Identity = 165/516 (31.98%), Postives = 281/516 (54.46%), Query Frame = 0
Query:   26 KSDAFTSIHDIKQILHKERVLTRYLNLAIEAEKERLGELEGMRDSMKMKLLNLNISSMDDYVGNPLNALHTIRRFTADWNEITNTLNTTRVQEFFNEWDRNVKL-PTLEDQKGAVSGILRLQNFYKINTRNVSRGFLSSTNPISKTEEIGVGLMWAMGYEAFKQKEWFLMKEWLDLALERIGDLEQSDGCKRSWIVDFLSYAEFQLGDYERSLDLAYQCLEYSPDDQKHHNNIEQCKKKISKGRKKSST---------------KPVEQLRYQ-----LCRGEGMRKPTIDEELQMVCWYK--NDQPILRYKPQKVERLWARPEIVMFRELLNDEQTGTLIDLSLQKLVRAGLNGQDVTSEKYTNSRVAKHAWLSMKESPIIRNMGKRAQAMTNLNMKYAEHLQIANYGIGGHYDAHYDYQTGE--NVFPDLKTGNRIATLMYYLSDVEAGGGTAFTFGKTTVYPSKGDAVFWWNLKQNGKVDESSKHAGCPVLMGQKWIANWWIHEYGQEFRRPC 516
            +++ FTSI  +  +++ E+ L + L   I  E+ +L +++   + M+  L + + +  + Y+ +P+NA   ++R   DW  + + +       F        +  PT ED+ GA   ++RLQ+ Y+++   +SRG L  T   +    + V   + MG  A+ + +++    W++  L+++   E++   K S ++D+LSYA FQLGD  R+L+L  + L   P  ++   N+   ++ + + R+K+ T               +PV+ L  +     LCRGEG+ K T   + ++ C Y   N  P L   P K E  W  P IV + ++++DE+   + +++  KL RA +           + RV+K +WL   + P++  + +R Q +T L +K AE LQ+ANYG+GG Y+ H+D+   +  + F  L TGNR+AT + Y+SDVEAGG T F      ++P KG AVFW+NL ++G+ D  ++HA CPVL+G KW++N W HE GQEF RPC
Sbjct:   20 QAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWANKME-ALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQFFPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAM---LSVDDCFGMGRSAYNEGDYYHTVLWMEQVLKQLDAGEEATTTK-SQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHERAGGNLRYFEQLLEEEREKTLTNQTEAELATPEGIYERPVDYLPERDVYESLCRGEGV-KLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAKPKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQVANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWPKKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPC 529          
The following BLAST results are available for this feature:
BLAST of TCONS_00010072-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
P4HA24.373e-9131.98Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapie... [more]
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