TCONS_00008580-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00008580-protein
Unique Name	TCONS_00008580-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	872

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00008580-protein ID=TCONS_00008580-protein|Name=TCONS_00008580-protein|organism=Clytia hemisphaerica|type=polypeptide|length=872bp
MNLQMSLTVFYHIHLFTYVFGINYIVFYDQHFTDQINLINFKSISIDQND
AWDLIRFNGNDTLHNISTINHRITDDNVVFVFTNYIPFVSEYYHGSSDLI
LKFGTSLQIMEKSATKHTNNMCLMFTQSMRRSLTYLMYSLLKPQVAIIMD
SSACAMNFFDDLEQSVKPSQYSKWFKVNLKRVIFSQDENHEILRSEFYNI
KSGGFQLVILLVAGHLQSHVFSDANHFNLLGSMPLWVIPNFKTSGDEICF
EFQPARILSFDLERRYENQPYSKIEDIVKSSVGLIRDKMTSSLLLQSEEG
EEELITDIYRKAQEVEELEHQQRMLLNLRYRNIAISSTNWIEEKAVIENY
HFHLVKNNLNFLQPLVPLGNDISRIKCVTVVDEPFTIIDDSLYDSYQNKC
TSGMKCVQIINQNGAAVRKISCCVGFIIDLFSLVLKEVEVKPDLYIVEDG
KYGVMNNKGVWDGMIGDVISGKADLAVAGITITESREKHVNFTLPFLEAE
MGIIVKPIKRVLDFVNFEFISPLSGELQLVLWFVVVGIMVLNYTFENNLY
VYSLTTENRPKYAYYSTFESMTYISGVFLQRDLGGVNPKRPGTRLSALVF
AFGMVIVVTTYTAVLAAQSVQDQEENPFEGSKDIRMRNPSSDFRYGLLKS
SNYETYFRNSEIETLRWMGKFMEKYNVESTREGVEKVKNGSLEAFIDDYK
FLYWYVSNDQSCELRVVQDALMKGGYGFAMNKDFIHAANVNQAIIKYTGS
HELNVLFNKWFRNACSSAQSTPVMVRLGINHFGGLFLLLCTTIAACFPLL
LPEHWYAKYFKDKVSQQIKGIFVKEKTQSDLQKANVKLRATLSCGLPADK
RERSFSVIDAIRKRAEALAKFE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_004799	XLOC_004799	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00008580	TCONS_00008580	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR019594	Glu/Gly-bd
IPR001638	Solute-binding_3/MltF_N
IPR001320	Iontro_rcpt

Vocabulary: **Molecular Function**
Term	Definition
GO:0005234	extracellular-glutamate-gated ion channel activity
GO:0004970	ionotropic glutamate receptor activity

Vocabulary: **Cellular Component**
Term	Definition
GO:0016020	membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0016020	membrane
molecular_function	GO:0005234	extracellular-glutamate-gated ion channel activity
molecular_function	GO:0004970	ionotropic glutamate receptor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR019594	Ionotropic glutamate receptor, L-glutamate and glycine-binding domain	SMART	SM00918	Lig_chan_Glu_bd_2	coord: 414..470 e-value: 3.3E-9 score: 46.6
IPR019594	Ionotropic glutamate receptor, L-glutamate and glycine-binding domain	PFAM	PF10613	Lig_chan-Glu_bd	coord: 417..506 e-value: 3.3E-23 score: 82.0
IPR001638	Solute-binding protein family 3/N-terminal domain of MltF	SMART	SM00062	AABind_6	coord: 419..764 e-value: 0.0014 score: 15.6
IPR001320	Ionotropic glutamate receptor	SMART	SM00079	GluR_14	coord: 403..763 e-value: 2.3E-25 score: 100.3
IPR001320	Ionotropic glutamate receptor	PFAM	PF00060	Lig_chan	coord: 530..791 e-value: 3.7E-13 score: 49.5
None	No IPR available	GENE3D	3.40.190.10		coord: 616..727 e-value: 7.6E-21 score: 74.1
None	No IPR available	GENE3D	3.40.190.10		coord: 375..532 e-value: 1.6E-21 score: 75.9
None	No IPR available	SUPERFAMILY	53850	Periplasmic binding protein-like II	coord: 644..762 coord: 422..526

Blast

[Close]

BLAST of TCONS_00008580-protein vs. Swiss-Prot (Human)
Match: NMD3A (Glutamate receptor ionotropic, NMDA 3A OS=Homo sapiens GN=GRIN3A PE=1 SV=2)

HSP 1 Score: 196.052 bits (497), Expect = 1.279e-51
Identity = 142/495 (28.69%), Postives = 235/495 (47.47%), Query Frame = 0

Query:  375 IKCVTVVDEPFTI---IDDSLYDSYQNKCTSGMKCVQIINQNGAAVRKI----------------SCCVGFIIDLFSLVLKEVEVKPDLYIVEDGKYGVMNNKGVWDGMIGDVISGKADLAVAGITITESREKHVNFTLPFLEAEMGIIVKPIKRVLDFVNFEFISPLSGELQLVLWFVVVGIMVLNYTFENNLYVYSLTTENRPKYAYYSTFESMTYISGVFLQRDLGGVNPKRPGTRLSALVFAFGMVIVVTTYTAVLAAQSVQDQEENPFEGSKDIRMRNPSSDFRYGLLKSSNYETYFRNSEIETLRWMGKFMEKYNVESTREGVEKVKNGS--LEAFIDDYKFLYWYVSNDQSCELRVVQDALMKGGYGFAMNKDFIHAANVNQAIIKYTGSHELNVLFNKWFRNACSSAQSTPV--MVRLGINHFGGLFLLLC--------TTIAA--CFPLLLP--------EHWYAKYFKDKVSQQIKGIFVKEKTQ 828
            ++ VT+++ PF     +DD      +  C +G  C+  +  + + +  +                 CC G+ IDL   + +++    DLYIV DGKYG   N G W G++GD++ G A +AV   +I  +R + ++FT PF    +GI+V+   R        F+ PL   + L + FV + I  +  T       + LT + R +   +S   ++     +   R +    PK    R    ++A   +  ++TYTA LAA  V ++      G  D ++ +PS  FR+G ++ S+ E Y R S  E    M ++M +YNV +T +GVE +KN    L+AFI D   L + VS D  C+L  V       GYG  +  +    AN+++ I +Y     +++L +KW+R      +S  V   +++GI HF GLF+LLC        TTI     + LLLP        ++W   +   ++ + I   F++EK Q
Sbjct:  515 LRVVTLIEHPFVFTREVDD------EGLCPAGQLCLDPMTNDSSTLDSLFSSLHSSNDTVPIKFKKCCYGYCIDLLEKIAEDMNFDFDLYIVGDGKYGAWKN-GHWTGLVGDLLRGTAHMAVTSFSINTARSQVIDFTSPFFSTSLGILVR--TRDTAAPIGAFMWPLHWTMWLGI-FVALHITAVFLTLYEWKSPFGLTPKGRNRSKVFSFSSALNICYALLFGRTVAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPE----MHEYMRRYNVPATPDGVEYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTANISELISQYKSHGFMDMLHDKWYRVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVYRLLLPRIKNKSKLQYWL--HTSQRLHRAINTSFIEEKQQ 993

The following BLAST results are available for this feature:

BLAST of TCONS_00008580-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00008580-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
NMD3A	1.279e-51	28.69	Glutamate receptor ionotropic, NMDA 3A OS=Homo sap...	[more]

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TCONS_00008580-protein (polypeptide) - C. hemisphaerica