TCONS_00008394-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00008394-protein
Unique NameTCONS_00008394-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length808

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00008394-protein ID=TCONS_00008394-protein|Name=TCONS_00008394-protein|organism=Clytia hemisphaerica|type=polypeptide|length=808bp
MASNTPKIQKLDEVVVNRIAAGEVIQRPANAIKEMIENSLDAKSKSIQVT
VKDGGLKLLQIQDDGCGIRKEDMHIVCERFTTSKLASFDDLKSIATYGFR
GEALASISHVAHLTITTKTGDSPCAFKAKYEDGKMVPLQVGGKVEAKACA
GNKGTQITVEDLFYNVAVRRKALRNTNEEHAKIVDVISKYAIHNPSVGFS
LKKVGNSVGDVRTSPKSTVIDNIKTIYGPTLSKELLEVTHEDTQYAFKMH
AFVSNANYSIKKCTLLLFINHRLVESTALRKALDAVYVNYLPKDKHPFMY
MSLELNPINLDVNVHPTKHEVKFLHEEAIIESIQKCVETKLLGSNESRQY
YTQSLIPKMLSAGVDCPVADIVQGNQSDKNNNANEGESEKKKLYAHQMVR
TDAREQKIEAFFPYKAQVKSPTQCSKVTEETVNQTSHVNKENVETDGASN
ATILTVDSELHGNEHSNTSNQNGIPDDQSGGHLTEVNELPREERKENGSE
GATTINLLQDEEGDVQMKDVEQNTRRGDEHSNNTHQKRHAADVKQPVAKS
SSKISSTACDERTMKLTSIRNLRRQIEDNEHLGVKKILEEHKFVGCVNRS
LALMQHLTQLYLVNVQNLSQELFYEIIIFRFGNFGYLELSEPAPIFELVR
LVLDTPESGWEPEDGEKDELAKYTVDLLKSKADMLMDYFSVEINEQGELT
AIPLLLSNYTPNWNKLPLLMLRLASEVDWDNEQQCFHDFAIELSDFYSTG
GSKQQTEDEDEGEWKHQIEHLIFPALRNTFIPPKRFSNDGCFLEVANLPD
LYKVFERC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_004712XLOC_004712Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00008394TCONS_00008394Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013507DNA_mismatch_repair_C
IPR002099DNA_mismatch_repair_fam
IPR003594HATPase_C
IPR014721Ribosomal_S5_D2-typ_fold_subgr
IPR032189Mlh1_C
IPR014762DNA_mismatch_repair_CS
IPR020568Ribosomal_S5_D2-typ_fold
Vocabulary: Biological Process
TermDefinition
GO:0006298mismatch repair
Vocabulary: Molecular Function
TermDefinition
GO:0030983mismatched DNA binding
GO:0005524ATP binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006298 mismatch repair
molecular_function GO:0005524 ATP binding
molecular_function GO:0030983 mismatched DNA binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR013507DNA mismatch repair protein, C-terminalSMARTSM01340DNA_mis_repair_2coord: 223..342
e-value: 1.5E-43
score: 160.7
IPR013507DNA mismatch repair protein, C-terminalPFAMPF01119DNA_mis_repaircoord: 223..341
e-value: 1.7E-31
score: 108.2
IPR002099DNA mismatch repair protein familyTIGRFAMTIGR00585TIGR00585coord: 7..321
e-value: 5.7E-99
score: 329.7
NoneNo IPR availablePFAMPF13589HATPase_c_3coord: 29..131
e-value: 1.2E-11
score: 44.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 431..450
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 461..556
NoneNo IPR availableCDDcd00075HATPase_ccoord: 31..120
e-value: 3.60446E-8
score: 51.1082
NoneNo IPR availableCDDcd03483MutL_Trans_MLH1coord: 218..342
e-value: 3.31682E-61
score: 202.079
IPR003594Histidine kinase-like ATPase, C-terminal domainGENE3D3.30.565.10coord: 3..210
e-value: 5.7E-40
score: 136.7
IPR003594Histidine kinase-like ATPase, C-terminal domainSUPERFAMILY55874ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinasecoord: 7..228
IPR014721Ribosomal protein S5 domain 2-type fold, subgroupGENE3D3.30.230.10coord: 228..341
e-value: 4.7E-31
score: 106.5
IPR032189DNA mismatch repair protein Mlh1, C-terminalPFAMPF16413Mlh1_Ccoord: 565..808
e-value: 2.0E-86
score: 289.6
IPR014762DNA mismatch repair, conserved sitePROSITEPS00058DNA_MISMATCH_REPAIR_1coord: 98..104
IPR020568Ribosomal protein S5 domain 2-type foldSUPERFAMILY54211Ribosomal protein S5 domain 2-likecoord: 206..340

Blast
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BLAST of TCONS_00008394-protein vs. Swiss-Prot (Human)
Match: MLH1 (DNA mismatch repair protein Mlh1 OS=Homo sapiens GN=MLH1 PE=1 SV=1)

HSP 1 Score: 803.897 bits (2075), Expect = 0.000e+0
Identity = 412/815 (50.55%), Postives = 543/815 (66.63%), Query Frame = 0 
Query:    8 IQKLDEVVVNRIAAGEVIQRPANAIKEMIENSLDAKSKSIQVTVKDGGLKLLQIQDDGCGIRKEDMHIVCERFTTSKLASFDDLKSIATYGFRGEALASISHVAHLTITTKTGDSPCAFKAKYEDGKMVPLQVGGKVEAKACAGNKGTQITVEDLFYNVAVRRKALRNTNEEHAKIVDVISKYAIHNPSVGFSLKKVGNSVGDVRTSPKSTVIDNIKTIYGPTLSKELLEVTHEDTQYAFKMHAFVSNANYSIKKCTLLLFINHRLVESTALRKALDAVYVNYLPKDKHPFMYMSLELNPINLDVNVHPTKHEVKFLHEEAIIESIQKCVETKLLGSNESRQYYTQSLIPKMLSAGVDCPVADIVQGNQSDKNNNANEGESEKKKLYAHQMVRTDAREQKIEAFF-PYKAQVKSPTQCSKVTEETVNQTSHVNKENVETDGASNATILTVDSELHGNEHSNTSNQNGIPDDQSGGHLTEVNELPREERKENGSEGATTINLLQDEEGDVQMKDVEQNTRRGDEHSNNTHQKRHAADVKQPVAKSSSKISSTACD--ERTMKLTSIRNLRRQIEDNEHLGVKKILEEHKFVGCVNRSLALMQHLTQLYLVNVQNLSQELFYEIIIFRFGNFGYLELSEPAPIFELVRLVLDTPESGWEPEDGEKDELAKYTVDLLKSKADMLMDYFSVEINEQGELTAIPLLLSNYTPNWNKLPLLMLRLASEVDWDNEQQCFHDFAIELSDFYST-----------GGSKQQTEDEDEGEWKHQIEHLIFPALRNTFIPPKRFSNDGCFLEVANLPDLYKVFERC 808
            I++LDE VVNRIAAGEVIQRPANAIKEMIEN LDAKS SIQV VK+GGLKL+QIQD+G GIRKED+ IVCERFTTSKL SF+DL SI+TYGFRGEALASISHVAH+TITTKT D  CA++A Y DGK+       K   K CAGN+GTQITVEDLFYN+A RRKAL+N +EE+ KI++V+ +Y++HN  + FS+KK G +V DVRT P ++ +DNI++I+G  +S+EL+E+  ED   AFKM+ ++SNANYS+KKC  LLFINHRLVEST+LRKA++ VY  YLPK+ HPF+Y+SLE++P N+DVNVHPTKHEV FLHEE+I+E +Q+ +E+KLLGSN SR Y+TQ+L+P     G+  P  ++V+   S  +++ +       K+YAHQMVRTD+REQK++AF  P    + S  Q + VTE+  + +S   ++  E                                        E+ ELP           A      Q  EGD      E + +RG   SN   + R  +DV+  V   S K  + AC    R + LTS+ +L+ +I +  H  ++++L  H FVGCVN   AL QH T+LYL+N   LS+ELFY+I+I+ F NFG L LSEPAP+F+L  L LD+PESGW  EDG K+ LA+Y V+ LK KA+ML DYFS+EI+E+G L  +PLL+ NY P    LP+ +LRLA+EV+WD E++CF   + E + FYS             G + +        WK  +EH+++ ALR+  +PPK F+ DG  L++ANLPDLYKVFERC
Sbjct:    8 IRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTSIQVIVKEGGLKLIQIQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTADGKCAYRASYSDGKL-------KAPPKPCAGNQGTQITVEDLFYNIATRRKALKNPSEEYGKILEVVGRYSVHNAGISFSVKKQGETVADVRTLPNASTVDNIRSIFGNAVSRELIEIGCEDKTLAFKMNGYISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSLEISPQNVDVNVHPTKHEVHFLHEESILERVQQHIESKLLGSNSSRMYFTQTLLP-----GLAGPSGEMVKSTTSLTSSSTS---GSSDKVYAHQMVRTDSREQKLDAFLQPLSKPLSSQPQ-AIVTEDKTDISSGRARQQDE----------------------------------------EMLELPAP---------AEVAAKNQSLEGDTTKGTSEMSEKRGPTSSNPRKRHREDSDVEM-VEDDSRKEMTAACTPRRRIINLTSVLSLQEEINEQGHEVLREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLPLLIDNYVPPLEGLPIFILRLATEVNWDEEKECFESLSKECAMFYSIRKQYISEESTLSGQQSEVPGSIPNSWKWTVEHIVYKALRSHILPPKHFTEDGNILQLANLPDLYKVFERC 756
The following BLAST results are available for this feature:
BLAST of TCONS_00008394-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MLH10.000e+050.55DNA mismatch repair protein Mlh1 OS=Homo sapiens G... [more]
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