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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00007901-protein ID=TCONS_00007901-protein|Name=TCONS_00007901-protein|organism=Clytia hemisphaerica|type=polypeptide|length=945bp
MRFLVIFVCIIACAVAFSVVKLEENNGDVIEKRSPNQNNRRVQEQRRRQE
EERRRKEDQRRRQEEQRRRQEEERRRQEERRRQEEHRRKEQEKIKQEQER
RKQEQEKQKQEAERRRQEEERRHKEADKRRKEQEEKRRQQEERRRQEEER
RQREHLEREQRKIENEKKWREKLREERKNERERKQQWEKEYQRLKQQNRQ
NQAYWNLETDHKEDNYPQEMKEKVQRGEHILPNEEDKFENEFGRYKTRTA
TKVIDLLTAINSGHDVENLDEGDMMKDAPNFEVENMEQTKGYCKKTENKR
KSICRNQGGRGRRAVEPVYGDDEAWVRKKRDGRRDRVYLWIDRRVPYEID
SALAESQTTIITALKEIEAKTCVRFVSRSSDEKNWIKFVKKSGCWSSVGR
KFWVDGYQELSLGDGCIYHGIIMHEVMHALGFYHEQSRSDRDQYVEIFWE
NIQPGKENNFAKETRQTSDLLGAAYDYSSIMHYGKYSFALNAQKASMLSI
RNPAQELGQREKLSSTDIYQINQLYSCHVSGNGWSAWSSYGPCDLSCNKK
RSRFCMDSQDRTSCPNPTSTVMLSWGIDEQMSKCSHAECNAPLNGHWGRW
GDWGQCSVTCEEGVQTRSRACSDPAPKNGGKDCVGSSTQSQKCIKRSCTS
GPADCFFDIDEEPLCKWTQSTSDNLDWTRKAGTTPSSSTGPSGDHTTGTG
YYLFMESSSPAQNGWKARLESPVLSNVERCMKFAYHMYGHSTGTLSVRVK
NLKTNQEEEVFTKSGDQLNEWKEKELDISSADQYKVIIEATRAFGFQGDI
AIDDIVISNGKCGSTGAVPPKLIPTVTKVGCYRDVGYIDGKRPFPQYKNF
REEINWEAYMQSLNETVFKCASHAREHKFEFFAVEYYGECWTGETAEINY
GRDGEATDCFPEPHHGLGPFLVGSDYTMMVYRWEDIPENLLKGSK Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Cellular Component
| Term | Definition |
|---|
| GO:0016020 | membrane |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004222 | metalloendopeptidase activity |
| GO:0008237 | metallopeptidase activity |
| GO:0008270 | zinc ion binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006508 | proteolysis |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006508 |
proteolysis |
| cellular_component |
GO:0016020 |
membrane |
| molecular_function |
GO:0004222 |
metalloendopeptidase activity |
| molecular_function |
GO:0008237 |
metallopeptidase activity |
| molecular_function |
GO:0008270 |
zinc ion binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 39..204 |
| None | No IPR available | PRINTS | PR01705 | TSP1REPEAT | coord: 632..643
score: 32.59
coord: 595..608
score: 44.64
coord: 613..624
score: 45.09 |
| None | No IPR available | GENE3D | 2.60.120.200 | | coord: 649..812
e-value: 1.1E-50
score: 171.4 |
| None | No IPR available | GENE3D | 2.30.90.10 | | coord: 533..584
e-value: 0.0064
score: 16.5 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 30..157 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 676..695 |
| None | No IPR available | SUPERFAMILY | 55486 | Metalloproteases ("zincins"), catalytic domain | coord: 336..528 |
| IPR000998 | MAM domain | PRINTS | PR00020 | MAMDOMAIN | coord: 703..719
score: 26.32
coord: 795..808
score: 40.23
coord: 663..681
score: 26.32
coord: 729..740
score: 34.65
coord: 776..790
score: 21.75 |
| IPR000998 | MAM domain | SMART | SM00137 | MAM_2 | coord: 650..814
e-value: 2.7E-50
score: 183.1 |
| IPR000998 | MAM domain | PFAM | PF00629 | MAM | coord: 655..812
e-value: 1.6E-43
score: 148.3 |
| IPR000998 | MAM domain | PROSITE | PS50060 | MAM_2 | coord: 653..814
score: 34.926 |
| IPR000998 | MAM domain | CDD | cd06263 | MAM | coord: 661..812
e-value: 2.74309E-50
score: 174.103 |
| IPR001506 | Peptidase M12A | PRINTS | PR00480 | ASTACIN | coord: 435..452
score: 54.72
coord: 360..378
score: 37.02
coord: 474..489
score: 53.12
coord: 513..526
score: 44.29
coord: 416..434
score: 54.47 |
| IPR001506 | Peptidase M12A | PFAM | PF01400 | Astacin | coord: 339..528
e-value: 8.0E-65
score: 217.9 |
| IPR006026 | Peptidase, metallopeptidase | SMART | SM00235 | col_5 | coord: 336..479
e-value: 9.6E-49
score: 177.9 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SMART | SM00209 | TSP1_2 | coord: 534..590
e-value: 0.1
score: 18.0
coord: 597..649
e-value: 9.5E-14
score: 61.7 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | GENE3D | 2.20.100.10 | | coord: 593..648
e-value: 1.9E-16
score: 59.6 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PFAM | PF00090 | TSP_1 | coord: 599..648
e-value: 1.5E-11
score: 44.3 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PROSITE | PS50092 | TSP1 | coord: 594..649
score: 13.721 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SUPERFAMILY | 82895 | TSP-1 type 1 repeat | coord: 594..644 |
| IPR002889 | Carbohydrate-binding WSC | PFAM | PF01822 | WSC | coord: 830..906
e-value: 1.3E-4
score: 21.9 |
| IPR024079 | Metallopeptidase, catalytic domain | GENE3D | 3.40.390.10 | | coord: 332..529
e-value: 2.8E-56
score: 190.1 |
| IPR034035 | Astacin-like metallopeptidase domain | CDD | cd04280 | ZnMc_astacin_like | coord: 342..525
e-value: 3.32638E-83
score: 266.359 |
| IPR013320 | Concanavalin A-like lectin/glucanase domain | SUPERFAMILY | 49899 | Concanavalin A-like lectins/glucanases | coord: 652..812 |
Blast
BLAST of TCONS_00007901-protein vs. Swiss-Prot (Human)
Match: ASTL (Astacin-like metalloendopeptidase OS=Homo sapiens GN=ASTL PE=1 SV=4) HSP 1 Score: 150.599 bits (379), Expect = 5.197e-39 Identity = 79/190 (41.58%), Postives = 119/190 (62.63%), Query Frame = 0
Query: 345 VPYEIDSALAE-SQTTIITALKEIEAKTCVRFVSRSSDEKNWIKFVKKSGCWSSVGRKFWVDGYQELSLGDGCIY--HGIIMHEVMHALGFYHEQSRSDRDQYVEIFWENIQPGKENNFAKETRQTSDLLGAAYDYSSIMHYGKYSFALNAQKASMLSIRNPAQELGQREKLSSTDIYQINQLYSCHVSG 531
VP+ + S E S+ I+ AL E E TC+RFV+ D++++I + GC+SSVGR G Q +SL C+ GI++HE+MH LGF+HE +R+DRD+Y+ + W I PG E NF K Q+S++L YDYSS+MHYG+ +F+ ++ + P+ +GQR LS++DI ++ +LY C SG
Sbjct: 104 VPFLLSSKYDEPSRQVILEALAEFERSTCIRFVTYQ-DQRDFISIIPMYGCFSSVGRS---GGMQVVSLAPTCLQKGRGIVLHELMHVLGFWHEHTRADRDRYIRVNWNEILPGFEINFIKS--QSSNML-TPYDYSSVMHYGRLAFSRRGLP-TITPLWAPSVHIGQRWNLSASDITRVLKLYGCSPSG 285
The following BLAST results are available for this feature:
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