TCONS_00007371-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00007371-protein vs. Swiss-Prot (Human)
Match: OTOF (Otoferlin OS=Homo sapiens GN=OTOF PE=1 SV=3)

HSP 1 Score: 610.912 bits (1574), Expect = 0.000e+0
Identity = 351/922 (38.07%), Postives = 518/922 (56.18%), Query Frame = 0

Query:    1 YLKLDLTVLAEGDLVK---EAPALDDDDIDSNPLLPDGLPPE------------------LNSGMLAAVRKAFSGETRLRDLADPFVTITFAGQEASTKVIEKCYDPEWNEEITFCDLFPSLCRRIKVQLRDKDVTKIETVGTTWIDLSEISNNNANVHKYNDAINFPPTFGPTWVNLYGSTRDFSFIDKDQQLNEGMEEGIGYRGRILMYIKTTEGESASNDEICN---INVKAAFPISDLAPGKEETFQLFCCIYEASMIHKANADKPCRFEMNIGNYGNTIDGKMISFKDDDDDNDDEEXTIDGKMISFKDDDDDNDDEE----DEDPFVRPLTKEYDCESADKEYYHIPFGARKPTMGIRFPWEDHRRRCYLTNIMEKLKMKLEDELDDVRTLLSIDSQDTYLYLQDALKE-------FISYCDVISGNLSKITGAKAGVTLLDEKRRKLCEKETEVMQKQAKSILDELK-----DNKRIEKHYFKVLKILNRIDKIMIEPQNAIPDVFLWLMSGGKRKCYVRIPVNQLMYSPIEAESGKNAGRKQTYLLSLPGKAGYGEAGWAIHCKLTCLIWLGVMKNKNDMLIDAPEEF-DVIPANSRKSTAPVPTQLKYLCKHKYILRAHLYQARGLIGSDDSGLSDAFARVVFNNQAAETRIIYETRNPTWNQMLILFDLTIWGDIDPVVENPPTIMIEIFDYDPGGEIEFIGRVMARPLVKKADSPYEGPLFPPKLEWFQIYRGDLPAGEMLAAFELFQVHPEEAELAAKMKQAQDEGQIYELTPEELEENKSNIPLEEAIQEIDEYEIVYFIVPLNIQPVMEMRTIEVLFWGVRELKPISFYKTVEKPQVFVDCVGKGVASPIIESVKKNPNFEEPYNKFELMLPIEDRYCPPLTFSVKEEHMFGNEFLIGTAIVKSLLRF 881
            Y+K D+ V+ +GD +K   +A   D+DDI+ N LLP+G+PPE                  +N+ ++A V+KAF GE +  DL DP+V + FAGQ+  T V +  Y+P WNE++ F DLFP LC+R+KVQ+RD D      +GT +IDL +ISN+            F PT GP WVN+YGSTR+++ +D+ Q LNEG+ EG+ +R R+L+ +   E    SN E+ +   + V+ A PIS+   GK E F LF    EASMI + N DKP  FE+ IGNYGN +DG     +        +E  +D  +I    DD+  D  +       P +RP       +  D+ Y+H+P+  RKP + I+  W D RRR Y  NIM+ +  KLE+ L+D++ ++  +       L+  L+E       F+S  D   G+ S+        T LD +R K C +E E M +QA+ +  ++K     D  R+ +++ + L+ L        EPQ++IPD+F+W+MS  KR  Y R+P   L++S +E E+GK+  + +T  L LPGK G+G AGW +  K+   +WLG+ K + + L   P  F +V  A      A  P  L Y  K  + LRAH+YQAR L  +D SGLSD FARV F NQ+  T ++ ET  PTW+QML+  +L ++G+   + ++PP I+IEI+D D  G+ +F+GR  A+PLVK AD  Y  P FPP+LE++QIYRG+  AG++LAAFEL Q+ P                             K+++P      ++D   I+   VP+ I+PV+    +EVLFWG+R+LK ++  + V++P+V ++C GKGV S +I + KKNPNF      FE+ LP  +   PPL   V +   FG   L+G+  V SL RF
Sbjct:  372 YVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENK--DLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK--------GFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGL-AVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVD--LIQNASDDEAGDAGDLASVSSTPPMRP-------QVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLADKDQGHSSR--------TRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLAD------EPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPA---------------------------GKADLPPINGPVDVDRGPIM--PVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQ-VDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRF 1229          

HSP 2 Score: 562.377 bits (1448), Expect = 1.945e-166
Identity = 299/654 (45.72%), Postives = 413/654 (63.15%), Query Frame = 0

Query: 1433 IDWWSRFY---ETIKDKKRVEEAIAKKTKKIKKEREKQGKKFDLE--------------EEEQSGAFDGIEEDVMKKNLMINPKIVRIKIYNTELEDVECFSGFNDVLHSFVLLRGKSNGNDDD---DERRIFGKFKGAIKVWKHPLPDFFKNPS---LVLGSFQMLPTRDPLDVLCRVYIVRALNLTATDAGGSADPYIQLRIGKTVIKDVEGKIENNLNPTFGRKFDIQIKIPQDNMLTVSIYDMDTLSST-LIGETKIDVEDRFFSKHKATCGMHSKYHICGFNKWRDPIKPTAILRRLCKDHGLIGPTFKTQDDSKTCLIATEQERYKFHAEKYIVDESGNQKESEEPAALTALHYFHKIDTKGYALVPEHVETRKLFAPSAPGLEQGRVQLWVDLFDMDGPSPDAAVDITPRKPTAFELRVIIWNTEDVELGDINILTGQPCADIYVKGWLEGLKHQAQQTDVHGSSLTGEGNFNWRFIFPFKYHKAEDKVVIIKK-SLFT--TTEEKMPGRLVLHCYDSDALSSDDFIGDITLQLNSCLKPTKTSKECKLETALENED--RFDIFKKKTMRGWWPFILDTEDEEPKVNGKVDAELQLLTAQESEEKPAGKGRNDPDALPPPNRPDLAMEWMMNPLKAFRYFLWEQYKF 2057
            +DWWS+++   +T+K++ R +E      ++ ++    +G K  ++              + + SG+  G E    KK     PKI  +K+Y  ELE    F  F D LH+F LLRGK+ G+D+D   +E RI G+FKG++ V+K PLP+     +      G FQ +P+ DP++VL RVY+VRA +L   D  G ADPYI +R+GKT I+D E  I   LNP FG+ FDI+   P ++MLTV++YD D + +  LIGETKID+E+RF+SKH+ATCG+   Y   G+N WRDP+KP+ IL RLCKD  + GP F      K            F     I DE+G +K ++E  AL AL ++  I   G  LVPEHVETR L  P  PG+EQGR++LWVD+F MD P+P   +DI+PRKP  +ELRVIIWNT++V L D +  TG+  +DI+V+GWL+G +   Q TDVH  SLTGEGNFNWR++FPF Y  AE+K+VI KK S+F+   TE K+P RL L  +D+D  S+DDF+G I L LN   +  KT+K+C +E A    D     IFK+K ++GWWP +   E++E ++ GKV+AEL LLTA+E+E+ P G  RN+PD L  PNRPD +  W +NPLK+ RYFLW  Y++
Sbjct: 1326 LDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKK-----PKIDELKVYPKELESE--FDNFEDWLHTFNLLRGKT-GDDEDGSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVA-------NRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRW 1964