TCONS_00007363-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00007363-protein
Unique NameTCONS_00007363-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length541

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00007363-protein ID=TCONS_00007363-protein|Name=TCONS_00007363-protein|organism=Clytia hemisphaerica|type=polypeptide|length=541bp
MGLNLLFITFMLLPLKVWPHKCIRFSNKVNHPYCKNIQDCERTYECNNPE
DSCFSLLKYDIEKQEFSHVISGCSESVVLESKACDHRSSKEHLTEDCVLG
LLDHKKEISLECCCIGDSCNQNLNFSMVNYTKLSGLKPQTTSLTKTDDHF
QKQRNGNTVHILIITLTIAIPIASILVIYLLYKHIKLDRTDSVSSDSLLS
KQPLFHKQKHIYQGQFTQVWKGYYEEHDVAIKLFASPVGAKCWTTEKDIY
SILNIQHQNILTLVHAGETHEDRPYHHNLVTQYIEYGSLYDYLRTVPMLS
FESITRLMTSMLQGVAYLHQNLLNKPMIAHRDLKSQNVMVRKNGSCCIGD
FGLAVAFHDDNGKSLSLAKTQVGSKIYMSPEILQGAIAYYADAFLHSDMY
SVALILWEILSRTNQTPYEPYQLPYERNVGRNPSISEMRHLVAEQSVRPY
LKAEWRQDEKLVTLCDTIENCWDSDTDARLSADCCLMRIKSVADEFSFPD
NENIVGILCNEKKRDDMRLDMTGATSSGVSSMGNDESQSTG
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_004142XLOC_004142Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00007363TCONS_00007363Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000333TGFB_receptor
IPR000719Prot_kinase_dom
IPR017194Transform_growth_fac-b_typ-2
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004702signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0004872receptor activity
GO:0046872metal ion binding
GO:0004674protein serine/threonine kinase activity
Vocabulary: Biological Process
TermDefinition
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0006468protein phosphorylation
GO:0007179transforming growth factor beta receptor signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
GO:0043235receptor complex
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007179 transforming growth factor beta receptor signaling pathway
biological_process GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0016020 membrane
cellular_component GO:0043235 receptor complex
molecular_function GO:0005524 ATP binding
molecular_function GO:0046872 metal ion binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004674 protein serine/threonine kinase activity
molecular_function GO:0004872 receptor activity
molecular_function GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000333Ser/Thr protein kinase, TGFB receptorPRINTSPR00653ACTIVIN2Rcoord: 100..123
score: 25.28
coord: 460..479
score: 57.0
coord: 341..362
score: 37.58
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 205..498
e-value: 1.7E-24
score: 97.4
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 205..485
e-value: 7.2E-35
score: 120.5
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 205..497
score: 33.022
IPR017194Transforming growth factor-beta receptor, type IIPIRSFPIRSF037393TGFRIIcoord: 16..203
e-value: 3.1
score: 3.3
coord: 204..522
e-value: 3.2E-51
score: 171.6
NoneNo IPR availableGENE3D3.30.200.20coord: 200..295
e-value: 8.9E-11
score: 41.1
NoneNo IPR availableGENE3D1.10.510.10coord: 296..499
e-value: 1.7E-35
score: 121.6
NoneNo IPR availableGENE3D2.10.60.10coord: 21..127
e-value: 2.2E-4
score: 21.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 521..541
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 328..340
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 205..487

Blast
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BLAST of TCONS_00007363-protein vs. Swiss-Prot (Human)
Match: AVR2A (Activin receptor type-2A OS=Homo sapiens GN=ACVR2A PE=1 SV=1)

HSP 1 Score: 228.794 bits (582), Expect = 2.302e-68
Identity = 130/395 (32.91%), Postives = 217/395 (54.94%), Query Frame = 0 
Query:  112 CCCIGDSCNQNLNFSMVNYTKLSGLKPQTTSLTKTDDHFQKQRNGNTVHILIITLTIAIPIASILV-IYLLYKHIKL-------DRTDSVSSDSLLSKQPLFHKQKHI-YQGQFTQVWKGYYEEHDVAIKLFASPVGAK-CWTTEKDIYSILNIQHQNILTLVHAGETHEDRPYHHNLVTQYIEYGSLYDYLRTVPMLSFESITRLMTSMLQGVAYLHQNLLN-----KPMIAHRDLKSQNVMVRKNGSCCIGDFGLAVAFHDDNGKSLSLAKTQVGSKIYMSPEILQGAIAYYADAFLHSDMYSVALILWEILSRTNQT--PYEPYQLPYERNVGRNPSISEMRHLVAEQSVRPYLKAEWRQDEKLVTLCDTIENCWDSDTDARLSADCCLMRI 489
            CCC G+ CN+  ++    + ++   +P +  +T    ++         +IL+ +L   + IA I++  + +Y+H K+          D               +   +  +G+F  VWK       VA+K+F  P+  K  W  E ++YS+  ++H+NIL  + A +          L+T + E GSL D+L+   ++S+  +  +  +M +G+AYLH+++       KP I+HRD+KS+NV+++ N + CI DFGLA+ F  + GKS      QVG++ YM+PE+L+GAI +  DAFL  DMY++ L+LWE+ SR      P + Y LP+E  +G++PS+ +M+ +V  +  RP L+  W++   +  LC+TIE CWD D +ARLSA C   RI
Sbjct:  103 CCCEGNMCNEKFSY----FPEMEVTQPTSNPVTPKPPYY---------NILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIF--PIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKA-NVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKF--EAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERI 479
The following BLAST results are available for this feature:
BLAST of TCONS_00007363-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
AVR2A2.302e-6832.91Activin receptor type-2A OS=Homo sapiens GN=ACVR2A... [more]
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