TCONS_00004887-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004887-protein
Unique NameTCONS_00004887-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1685

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004887-protein ID=TCONS_00004887-protein|Name=TCONS_00004887-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1685bp
MKAAQIISLILSTTICLLIFNQNVVTCLKNEKLHHVHRSIRKRDLWRIFG
VEDPTKVPPYEIFSPFIHEGSSIRIDDDRRKRSMDKSNSYRGEIKTRTLR
LGIPAFDKIHHLNMTQNKQLLTRNFKVEVLKQNGVKVVKREVEGNCYFHG
NVQGDFLSLAAMSICYGQLRGMFTDEKEHYFVEPVPHYLHHMHGEIHEKP
HIVFRRSLEETSTKYSGMFGSLLKKRSTEKPCGTKKNPHIRLARSATSTA
TDSKPTSSQSKTATTKTSNTKTTSEKEEEIEEEEEKKDTELDNNERYIEA
LAVVDQKMVNYHGEDAATQFALVVMNNVARLLRDASIGQNLVILGLNKLQ
LHTVDVPGLVINHHARNTLKSFGNWAQLSSDVDDRSDDHFDYAMLLTRYN
ICADRNQACDTRGLTETGGMCQWPYSASVNEDNGFELVYTVAHNIGHSLG
MNHDGDESSFICPDNEYLMASNINPEDWKDNRNHWSRCSRNYLRQFLKKD
QSKCLNDVPVFAHEVDYEKMDNKPGLLYDVSKQCEMQYGTGSKLCTRNME
NICSTMSCTNPSNPDKCFRSLYPAADGTKCAENKFCYHGRCIATSSEMHA
TDGGWSTWADDYQACSRSCGGGVQFRQRHCTAPRPSNGGKYCEGESRTYR
LCNTQKCGNGTTSPSYRSFQCSNLNGRLFGERKFEWEFKPSKIASCELGC
FIAQTGHGYNFGNVMDGTNCDQTDDGMFSDKCINGQCVPVGCDKKLGSSV
KFDRCGVCDGDGLTCVTGSERSNIAEASNSAGGIADALKSLKDMGFNMNN
LYGKSSLELSSSSKRSDISSSGAAKKEEYGWSKIKSGCSTSCGGGIETLT
AECRRLDDGSPVRENHCDQRSKPPTQQYPCKEEACPPIYQTSYWGDCSKT
CNAGFKRRNVRCVQKSANGIEFDLDMNMCSGARPTDTEACNKEPCPAEWI
AQPFGECSTICGSGVQNRDVLCQKTLKDGSLVTLHHDDCRQDTKPPTEQR
CNVHNPCPGDDGCGGIYTDRVGNFTSPGYPNKYPSDMECVHIIQVPKENV
IKLNFERMNIASPDKDCKNDFVKVMDGDCVSRLGESKFCGNSIPPLFIST
TNRLCVKFFSDDSKSDDGFLARYTAIDKPTQSQDQCNSNLTAPDGLISSP
NYPEFYPQNEECNVTITTEERPIRVKFHAFDVGNEGCDSDYVILSGGEES
KKFCGQKLPSEYVSKENVINVRFVSTSHQNQLKPGFVATYTSGSPESARR
RNNIPKPVVIKNDTLLTKKSIIPKEANSTFSIKAAFINTTNSIDTIAKDV
QISNRHEIKTAKFPTKQNTTVQLNRIKINNNTNALLNVTKGSIQNTSDTT
VTNQTLSNLKPNSINTTLDKMSNVTNLLSNRTKTITDQSKSSVNGANQST
SVKGTNQVAFIKSTQSDEIDMEVNSGRQTNDKKDMISSFTKESGNKRNDV
VFTKSTQNDQVNAEIQSRVDKLKKEGKHLTKDQRLFLEAMKDDTPKWIPE
PALPIINKTITVRKRNHTNRHPHHQNVKKDQIARPNANENERTHEIKIKA
TSENTQTKKDMISKHEIEMKKKISSKKLYITKPINYQNNLDGNLGECPSS
LRCMDLLLSYPCTYDDHCGPGLSCCQTACGYFQKMCLPKITRHCPLQLPL
MGHRVPCHAEGDCPLRHTCCLDLANNKYCRSLRED
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002768XLOC_002768Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004887TCONS_00004887Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013273Peptidase_M12B_ADAM-TS
IPR000884TSP1_rpt
IPR006586ADAM_Cys-rich
IPR000859CUB_dom
IPR002870Peptidase_M12B_N
IPR024079MetalloPept_cat_dom
IPR001590Peptidase_M12B
Vocabulary: Molecular Function
TermDefinition
GO:0008270zinc ion binding
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1462..1482
NoneNo IPR availableCOILSCoilCoilcoord: 273..300
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 226..292
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 294..509
IPR013273Peptidase M12B, ADAM-TSPRINTSPR01857ADAMTSFAMILYcoord: 726..745
score: 41.73
coord: 612..630
score: 56.93
coord: 746..765
score: 57.45
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 948..1008
e-value: 0.27
score: 14.4
coord: 605..658
e-value: 2.1E-10
score: 50.6
coord: 888..946
e-value: 1.9E-6
score: 37.4
coord: 831..886
e-value: 0.58
score: 11.4
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 947..1008
e-value: 2.6E-10
score: 40.1
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 601..657
e-value: 7.0E-18
score: 64.2
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 953..988
e-value: 0.011
score: 15.9
coord: 891..945
e-value: 1.3E-4
score: 22.0
coord: 605..657
e-value: 2.2E-7
score: 30.9
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 827..886
e-value: 4.8E-6
score: 26.4
coord: 888..946
e-value: 5.1E-12
score: 45.5
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 885..946
score: 10.863
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 599..658
score: 12.162
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 948..1008
score: 8.792
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 949..1007
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 888..945
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 600..657
IPR006586ADAM, cysteine-richSMARTSM00608acrcoord: 520..594
e-value: 0.002
score: -12.8
IPR000859CUB domainSMARTSM00042CUB_2coord: 1136..1243
e-value: 6.5E-18
score: 75.5
coord: 1013..1126
e-value: 8.7E-33
score: 124.9
IPR000859CUB domainGENE3D2.60.120.290coord: 1131..1247
e-value: 6.9E-25
score: 87.0
coord: 1009..1130
e-value: 3.4E-31
score: 107.3
IPR000859CUB domainPFAMPF00431CUBcoord: 1013..1123
e-value: 4.5E-26
score: 91.3
coord: 1136..1240
e-value: 1.9E-18
score: 66.7
IPR000859CUB domainPROSITEPS01180CUBcoord: 1013..1126
score: 24.749
IPR000859CUB domainPROSITEPS01180CUBcoord: 1136..1243
score: 20.723
IPR000859CUB domainCDDcd00041CUBcoord: 1136..1242
e-value: 3.51529E-21
score: 90.9346
IPR000859CUB domainCDDcd00041CUBcoord: 1013..1125
e-value: 5.70538E-32
score: 122.136
IPR000859CUB domainSUPERFAMILY49854Spermadhesin, CUB domaincoord: 1012..1126
IPR000859CUB domainSUPERFAMILY49854Spermadhesin, CUB domaincoord: 1135..1242
IPR002870Peptidase M12B, propeptidePFAMPF01562Pep_M12B_propepcoord: 74..204
e-value: 3.9E-24
score: 85.4
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 292..532
e-value: 2.0E-57
score: 194.0
IPR001590Peptidase M12B, ADAM/reprolysinPFAMPF01421Reprolysincoord: 296..509
e-value: 1.2E-18
score: 67.7
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 296..509
score: 20.327

Blast
[Close]
BLAST of TCONS_00004887-protein vs. Swiss-Prot (Human)
Match: ATS6 (A disintegrin and metalloproteinase with thrombospondin motifs 6 OS=Homo sapiens GN=ADAMTS6 PE=2 SV=2)

HSP 1 Score: 471.47 bits (1212), Expect = 3.358e-143
Identity = 335/1015 (33.00%), Postives = 483/1015 (47.59%), Query Frame = 0 
Query:   79 RRKRSMDKSNSYRGEIKTRTLRLGIPAFDKIHHLNMTQNKQLLTRNFKVEVLKQNGVKVVKREVEGNCYFHGNVQGD-FLSLAAMSICYGQLRGMFTDEKEHYFVEPVPHYLHHMHGEIHE--KPHIVFRRSLEETSTKYSGMFGSLLKKRSTEKPCGTKKNPHIRLARSATSTATDSKPTSSQSKTATTKTSNTKTTSEKEEEIEEEEEKKDTELDNNERYIEALAVVDQKMVNYHGEDAATQFALVVMNNVARLLRDASIGQNLVILGLNKLQLHTVDVPGLVINHHARNTLKSFGNWAQ--LSSDVD-----DRSDDHFDYAMLLTRYNICADRNQACDTRGLTETGGMCQWPYSASVNEDNGFELVYTVAHNIGHSLGMNHDGDESSFICPDNEY--LMASNINPEDWKDNRNHWSRCSRNYLRQFLKKDQSKCLNDVPVFAHEVDYEKMDNKPGLLYDVSKQCEMQYGTGSKLCTRNMENICSTMSCTNPSNPDKCFRSLYPAADGTKC----AENKFCYHGRCIATSSEMHATDGGWSTWADDYQACSRSCGGGVQFRQRHCTAPRPSNGGKYCEGESRTYRLCNTQKCGNGTTSPSYRSFQCSNLNGRLFGERKFEWE-FKPSKIASCELGCFIAQTGHGYNFGN-----VMDGTNCDQTDDGMFSDKCINGQCVPVGCDKKLGSSVKFDRCGVCDGDGLTCVT----------------------GSERSNIAEASNSAGGIA-----------------------------------DALKSLKDMGFNMNNLYGKSSLELSSSSKRSD----ISSSGAAKKE-EYGWS-KIKSGCSTSCGGGIETLTAECRRLDDGSPVRENHCDQRSKPPTQQYPCKEEACPPIYQTSYWGDCSKTCNAGFKRRNVRCVQKSANGIEFDLDMNMCSGARPTDTEACNKEPCPAEWIAQPFGECSTICGSGVQNRDVLCQKTLKDGSLVTLHHDDCRQDTKPPTEQRCNVHNPCP 1008
            RR+RSMD  +  +   K   L   + A+ K  HLN+T N   ++++F VE   ++G +  K +   NC++ G +Q     +  A+S C G L G+   E E YF+EP+ +         +E   PH+++++S  +    Y      +     + KP             + TST + S P +           NT     ++  +            + ER++E L V D+ MV YHG      + L VMN VA+L RD+S+G N+V + + +L + T D P L INHHA  +L SF  W +  LS   D     +    H D A+L+TRY+IC  +N+ C T GL    GMC+   S S+NED G    +T+AH IGH+ GMNHDG  +S     +E   LMA++I       N   WS CSR+Y+  FL   +  CL++ P    + D+      PG +YD  +QC  QYG  S+ C      +C  + C + SN  +C  +  PAA+GT C     E  +CY G C+   +   + DGGW  W+  +  CSR+CGGGV    RHC +P PS GGKYC GE + YR CNT  C  G  S  +R  QC++ +   F  + + W+ +    +  C L C       GYNF       V+DGT C+   D +  D CING+C  VGCD  LGS  + DRC VC GDG TC                        GS    + E + S   IA                                   D  +SL+ +G    NL     L+  +   R      I+ +G+   E  + W+ +  S CS +C GG++     C+RLDD S V+ N+CD  SKPP  Q  C  E CPP +    W +CSKTC+ G + R V C++K     E  LD + C   RP + E CN + CP +W+A  + EC+  CG G ++R VLC+ +  D S  T     C +++KPP   RC++   CP
Sbjct:   68 RRRRSMDPIDPQQAVSK---LFFKLSAYGKHFHLNLTLNTDFVSKHFTVEYWGKDGPQW-KHDFLDNCHYTGYLQDQRSTTKVALSNCVG-LHGVIATEDEEYFIEPLKNTTEDSKHFSYENGHPHVIYKKSALQQRHLYDHSHCGVSDFTRSGKP----------WWLNDTSTVSYSLPIN-----------NTHIHHRQKRSV------------SIERFVETLVVADKMMVGYHGRKDIEHYILSVMNIVAKLYRDSSLG-NVVNIIVARLIVLTEDQPNLEINHHADKSLDSFCKWQKSILSHQSDGNTIPENGIAHHDNAVLITRYDICTYKNKPCGTLGLASVAGMCEPERSCSINEDIGLGSAFTIAHEIGHNFGMNHDGIGNSCGTKGHEAAKLMAAHITA---NTNPFSWSACSRDYITSFLDSGRGTCLDNEPP---KRDFLYPAVAPGQVYDADEQCRFQYGATSRQCKYG--EVCRELWCLSKSN--RCVTNSIPAAEGTLCQTGNIEKGWCYQGDCVPFGTWPQSIDGGWGPWS-LWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLG--SRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNCL----AEGYNFYTERAPAVIDGTQCNA--DSL--DICINGECKHVGCDNILGSDAREDRCRVCGGDGSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAWTIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVLLQEQNLGIRYKFNVPITRTGSGDNEVGFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPPQWVALDWSECTPKCGPGFKHRIVLCKSS--DLS-KTFPAAQCPEESKPPVRIRCSLGR-CP 1018
The following BLAST results are available for this feature:
BLAST of TCONS_00004887-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ATS63.358e-14333.00A disintegrin and metalloproteinase with thrombosp... [more]
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