TCONS_00005551-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00005551-protein
Unique NameTCONS_00005551-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1061

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00005551-protein ID=TCONS_00005551-protein|Name=TCONS_00005551-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1061bp
MIMMNKKSKKVKKTKDCSTTSKSPTDSPSNSSFAPFTTIRKSFKRLKRKK
EQHQRVLSADSVFEHNDGVEDNISKTAIANKPKGSNQDSNQNILKRIASG
KRFRIKNNHNSRNVSSTTDIHKFDVVEWSSCESLNENFEKRMRKHNSLRR
SKASLLMPSSGKQGKISPPSTKITRYSSLNNILDSKTKPEVKWNSNQNVS
SADKENCGIIRLSPPKDEINGEKRKRPRQKANSASLPNICEEKLKPISIE
IEIETDDVDTSKNKDKILRAWLSSSDIKSEKIDVLLGMNRKRCSLIVLDD
SEEKKKIFGSTPFLDRPPIPSDPKPTLRRDQVLRRCVSTEGLSPKKRRSE
MEGYQRRTHKRALSDCHFIAQMPAEMKTSAIEIKNTSDKDLNNGASSIDK
EQEEEVKDCLSPPATPTAKSLLSSASAINFTEEKNFKTCDIFSSIQNIPS
FFNQNEEIWMKTISDQLPLAIAEALWDHTGLNEDDLAFSSGDVISVLYME
DEASWWWGVRKDGKEGWFPASYVRLRVVQEIDDELTEQVQKEESNTDTNE
KSSSQHTPTRSRSTRGNTFLTAMGLQTRSSSLTQHHHKNMEHLMAVRAKC
VEELVNTEKDYVQMLRNIIEGYLEKVRQEKSLFTAADAETIFGNIEELYH
FHKEFLKELQQAIKFDRMEESIVGHLFIKHKNRFEIYSKYCNNQPRSSAR
ISRLIKEKKYELFFETCRLRQNMIRLSLDGFLLSPVQRICKYPLQLKELL
KHTHSEHEDYNTLNEAKTCMQNVAAVINERKRRLENVNKLARWQLTVSNW
KDEDVVMKSSDLLFKGPLLKINNGRECERFVYLFDHQLLYFVKEENRRQP
LCYRGRVDLDTAIIENLGDNHVFIRGDTVSNVWRIWNTSKTKWCYFRADT
AEKKENWLKALENEREHVKEEQKQGFTVLPEVRSAAMESAYTKHIAGVKR
GRMRRKSICTNHPELETTYASGPLAGPINRTFSSTLATSSSSSSTRSSNN
SKSSLSTSPSSPTNNNNNNNMTSSYSIQSEDGPTVRKRVHKPKRKNSFRW
SLNSTIFEKYF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003165XLOC_003165Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00005551TCONS_00005551Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001452SH3_domain
IPR001849PH_domain
IPR000219DH-domain
IPR011993PH_dom-like
IPR001331GDS_CDC24_CS
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO:0005085guanyl-nucleotide exchange factor activity
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
GO:0035556intracellular signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035556 intracellular signal transduction
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0005085 guanyl-nucleotide exchange factor activity
molecular_function GO:0005515 protein binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 901..924
NoneNo IPR availableGENE3D1.20.900.10coord: 594..787
e-value: 4.5E-61
score: 205.4
NoneNo IPR availableGENE3D2.30.30.40coord: 220..555
e-value: 5.1E-17
score: 61.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 980..1043
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 210..235
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..36
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 537..566
NoneNo IPR availableCDDcd00160RhoGEFcoord: 597..778
e-value: 7.5227E-57
score: 194.053
IPR001452SH3 domainSMARTSM00326SH3_2coord: 470..527
e-value: 1.1E-15
score: 68.1
IPR001452SH3 domainPFAMPF00018SH3_1coord: 474..520
e-value: 1.7E-9
score: 37.0
IPR001452SH3 domainPROSITEPS50002SH3coord: 467..528
score: 14.268
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 467..526
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 812..918
e-value: 7.0E-10
score: 48.8
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 811..916
score: 10.895
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 600..779
e-value: 1.5E-62
score: 223.8
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 600..778
e-value: 1.1E-47
score: 162.6
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 596..780
score: 35.951
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 579..801
IPR011993PH domain-likeGENE3D2.30.29.30coord: 788..925
e-value: 2.8E-20
score: 71.8
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 787..938
IPR001331Guanine-nucleotide dissociation stimulator, CDC24, conserved sitePROSITEPS00741DH_1coord: 728..753

Blast
BLAST of TCONS_00005551-protein vs. Swiss-Prot (Human)
Match: ARHG4 (Rho guanine nucleotide exchange factor 4 OS=Homo sapiens GN=ARHGEF4 PE=1 SV=3)

HSP 1 Score: 360.918 bits (925), Expect = 2.617e-111
Identity = 193/519 (37.19%), Postives = 294/519 (56.65%), Query Frame = 0
Query:  469 LAIAEALWDHTGLNEDDLAFSSGDVISVLYMEDEASWWWGVRKDGKEGWFPASYVRLRVVQEIDDELTEQVQKEESNTDTNEKSSSQHTPTRSRSTRGNTFLTAMGLQTRSSSLTQHHHKNMEHLMAVRAKCVEELVNTEKDYVQMLRNIIEGYLEKVRQEKSLFTAADAETIFGNIEELYHFHKEFLKELQQAIKFDRMEESIVGHLFIKHKNRFEIYSKYCNNQPRSSARISRLIKEKKYELFFETCRLRQNMIRLSLDGFLLSPVQRICKYPLQLKELLKHTHSEHEDYNTLNEAKTCMQNVAAVINERKRRLENVNKLARWQLTVSNWKDEDVVMKSSDLLFKGPLLKIN--NGRECERFVYLFDHQLLYFVKEENRRQPLCYRGRVDLDTAIIENLGDNHVFIRGDTVSNVWRIWNTSKTKWCYFRADTAEKKENWLKALENEREHVKEEQKQGFTVLPEVRSAAMESAYTKHIAGVKRG--------RMRRKSICTNHPELETTYASGPLAGP 977
            +  AEALWDH  +++ +L F +GDVI V+   +   WWWG   DG EGWFPAS+VRLRV Q+           E ++ D                  GN+     G + +SS               +R   + E+++TE+DY++ LR+I EGY+ + R+   +F+     TIFGNIE++Y   K F+K L+Q    +R   S +G  F++H+  F+IYS+YCNN P +   +SRL K  KY  FFE CRL Q MI +SLDGFLL+PVQ+ICKYPLQL ELLK+TH +H D+  +  A   M+NVA +INERKRRLEN++K+A+WQ ++ +W+ ED++++SS+L++ G L ++     +  +R  +LFDHQL+Y  K+  RR  L Y+GR+D+D   + +L D        ++ N +R+   +            E+K+ WLKA   ERE V+ +Q+ GF++    R  AM +A  + + G  +         R +  ++ +N P+ +    + P   P
Sbjct:  196 VVCAEALWDHVTMDDQELGFKAGDVIEVMDATNR-EWWWGRVADG-EGWFPASFVRLRVNQD-----------EPADDDA--------------PLAGNSGAEDGGAEAQSSK------------DQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKP 675          
The following BLAST results are available for this feature:
BLAST of TCONS_00005551-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ARHG42.617e-11137.19Rho guanine nucleotide exchange factor 4 OS=Homo s... [more]
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