TCONS_00005551-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00005551-protein
Unique Name	TCONS_00005551-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1061

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00005551-protein ID=TCONS_00005551-protein|Name=TCONS_00005551-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1061bp
MIMMNKKSKKVKKTKDCSTTSKSPTDSPSNSSFAPFTTIRKSFKRLKRKK
EQHQRVLSADSVFEHNDGVEDNISKTAIANKPKGSNQDSNQNILKRIASG
KRFRIKNNHNSRNVSSTTDIHKFDVVEWSSCESLNENFEKRMRKHNSLRR
SKASLLMPSSGKQGKISPPSTKITRYSSLNNILDSKTKPEVKWNSNQNVS
SADKENCGIIRLSPPKDEINGEKRKRPRQKANSASLPNICEEKLKPISIE
IEIETDDVDTSKNKDKILRAWLSSSDIKSEKIDVLLGMNRKRCSLIVLDD
SEEKKKIFGSTPFLDRPPIPSDPKPTLRRDQVLRRCVSTEGLSPKKRRSE
MEGYQRRTHKRALSDCHFIAQMPAEMKTSAIEIKNTSDKDLNNGASSIDK
EQEEEVKDCLSPPATPTAKSLLSSASAINFTEEKNFKTCDIFSSIQNIPS
FFNQNEEIWMKTISDQLPLAIAEALWDHTGLNEDDLAFSSGDVISVLYME
DEASWWWGVRKDGKEGWFPASYVRLRVVQEIDDELTEQVQKEESNTDTNE
KSSSQHTPTRSRSTRGNTFLTAMGLQTRSSSLTQHHHKNMEHLMAVRAKC
VEELVNTEKDYVQMLRNIIEGYLEKVRQEKSLFTAADAETIFGNIEELYH
FHKEFLKELQQAIKFDRMEESIVGHLFIKHKNRFEIYSKYCNNQPRSSAR
ISRLIKEKKYELFFETCRLRQNMIRLSLDGFLLSPVQRICKYPLQLKELL
KHTHSEHEDYNTLNEAKTCMQNVAAVINERKRRLENVNKLARWQLTVSNW
KDEDVVMKSSDLLFKGPLLKINNGRECERFVYLFDHQLLYFVKEENRRQP
LCYRGRVDLDTAIIENLGDNHVFIRGDTVSNVWRIWNTSKTKWCYFRADT
AEKKENWLKALENEREHVKEEQKQGFTVLPEVRSAAMESAYTKHIAGVKR
GRMRRKSICTNHPELETTYASGPLAGPINRTFSSTLATSSSSSSTRSSNN
SKSSLSTSPSSPTNNNNNNNMTSSYSIQSEDGPTVRKRVHKPKRKNSFRW
SLNSTIFEKYF

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_003165	XLOC_003165	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00005551	TCONS_00005551	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001452	SH3_domain
IPR001849	PH_domain
IPR000219	DH-domain
IPR011993	PH_dom-like
IPR001331	GDS_CDC24_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0005085	guanyl-nucleotide exchange factor activity

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035556	intracellular signal transduction
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005085	guanyl-nucleotide exchange factor activity
molecular_function	GO:0005515	protein binding
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 901..924
None	No IPR available	GENE3D	1.20.900.10		coord: 594..787 e-value: 4.5E-61 score: 205.4
None	No IPR available	GENE3D	2.30.30.40		coord: 220..555 e-value: 5.1E-17 score: 61.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 980..1043
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 210..235
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..36
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 537..566
None	No IPR available	CDD	cd00160	RhoGEF	coord: 597..778 e-value: 7.5227E-57 score: 194.053
IPR001452	SH3 domain	SMART	SM00326	SH3_2	coord: 470..527 e-value: 1.1E-15 score: 68.1
IPR001452	SH3 domain	PFAM	PF00018	SH3_1	coord: 474..520 e-value: 1.7E-9 score: 37.0
IPR001452	SH3 domain	PROSITE	PS50002	SH3	coord: 467..528 score: 14.268
IPR001452	SH3 domain	SUPERFAMILY	50044	SH3-domain	coord: 467..526
IPR001849	Pleckstrin homology domain	SMART	SM00233	PH_update	coord: 812..918 e-value: 7.0E-10 score: 48.8
IPR001849	Pleckstrin homology domain	PROSITE	PS50003	PH_DOMAIN	coord: 811..916 score: 10.895
IPR000219	Dbl homology (DH) domain	SMART	SM00325	RhoGEF_3	coord: 600..779 e-value: 1.5E-62 score: 223.8
IPR000219	Dbl homology (DH) domain	PFAM	PF00621	RhoGEF	coord: 600..778 e-value: 1.1E-47 score: 162.6
IPR000219	Dbl homology (DH) domain	PROSITE	PS50010	DH_2	coord: 596..780 score: 35.951
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 579..801
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 788..925 e-value: 2.8E-20 score: 71.8
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 787..938
IPR001331	Guanine-nucleotide dissociation stimulator, CDC24, conserved site	PROSITE	PS00741	DH_1	coord: 728..753

Blast

[Close]

BLAST of TCONS_00005551-protein vs. Swiss-Prot (Human)
Match: ARHG4 (Rho guanine nucleotide exchange factor 4 OS=Homo sapiens GN=ARHGEF4 PE=1 SV=3)

HSP 1 Score: 360.918 bits (925), Expect = 2.617e-111
Identity = 193/519 (37.19%), Postives = 294/519 (56.65%), Query Frame = 0

Query:  469 LAIAEALWDHTGLNEDDLAFSSGDVISVLYMEDEASWWWGVRKDGKEGWFPASYVRLRVVQEIDDELTEQVQKEESNTDTNEKSSSQHTPTRSRSTRGNTFLTAMGLQTRSSSLTQHHHKNMEHLMAVRAKCVEELVNTEKDYVQMLRNIIEGYLEKVRQEKSLFTAADAETIFGNIEELYHFHKEFLKELQQAIKFDRMEESIVGHLFIKHKNRFEIYSKYCNNQPRSSARISRLIKEKKYELFFETCRLRQNMIRLSLDGFLLSPVQRICKYPLQLKELLKHTHSEHEDYNTLNEAKTCMQNVAAVINERKRRLENVNKLARWQLTVSNWKDEDVVMKSSDLLFKGPLLKIN--NGRECERFVYLFDHQLLYFVKEENRRQPLCYRGRVDLDTAIIENLGDNHVFIRGDTVSNVWRIWNTSKTKWCYFRADTAEKKENWLKALENEREHVKEEQKQGFTVLPEVRSAAMESAYTKHIAGVKRG--------RMRRKSICTNHPELETTYASGPLAGP 977
            +  AEALWDH  +++ +L F +GDVI V+   +   WWWG   DG EGWFPAS+VRLRV Q+           E ++ D                  GN+     G + +SS               +R   + E+++TE+DY++ LR+I EGY+ + R+   +F+     TIFGNIE++Y   K F+K L+Q    +R   S +G  F++H+  F+IYS+YCNN P +   +SRL K  KY  FFE CRL Q MI +SLDGFLL+PVQ+ICKYPLQL ELLK+TH +H D+  +  A   M+NVA +INERKRRLEN++K+A+WQ ++ +W+ ED++++SS+L++ G L ++     +  +R  +LFDHQL+Y  K+  RR  L Y+GR+D+D   + +L D        ++ N +R+   +            E+K+ WLKA   ERE V+ +Q+ GF++    R  AM +A  + + G  +         R +  ++ +N P+ +    + P   P
Sbjct:  196 VVCAEALWDHVTMDDQELGFKAGDVIEVMDATNR-EWWWGRVADG-EGWFPASFVRLRVNQD-----------EPADDDA--------------PLAGNSGAEDGGAEAQSSK------------DQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRPCYLTRQKHPALPSNRPQQQVLVLAEPRRKP 675

The following BLAST results are available for this feature:

BLAST of TCONS_00005551-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00005551-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ARHG4	2.617e-111	37.19	Rho guanine nucleotide exchange factor 4 OS=Homo s...	[more]

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TCONS_00005551-protein (polypeptide) - C. hemisphaerica