Smad6/7 protein (polypeptide) - C. hemisphaerica

Overview
NameSmad6/7 protein
Unique NameTCONS_00073440-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length424

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00073440-protein ID=TCONS_00073440-protein|Name=Smad6/7 protein|organism=Clytia hemisphaerica|type=polypeptide|length=424bp
MDEGNTICDSQKKLNLINKLWKNSVYMYNKKCCMIKKILRFSKLPKDKEQ
NHEVKELRRKVHSIFKTLTEDQLDILLKTLQANGGIDSECILVNTSTFRH
ITCRTTSFVPRTLLAKVFRFPNLKDEYLRCLSCCYNHSSCDETKVCINPF
HSSVVIESESPLPPYSELTPSTALFSESTTTTTLDDDDRHIPTHVALPRT
PTHPAFLGYKDLGSTCSSTSSTSSTSSERSHSGPERNWYGGPWCQITYWE
EKSRIGSRFDVAKDCVNVFETLPQGSGLDLSMLTRSRPNEASEKVKNDIG
YGFQLTREADGIWLYNRSDIVLFAGSPTIQLGSENLTQPVVKRLPPGNSV
LVYDPNLLPDLSTIEKPGLETTEDGMKSSSASKEMRGGTQPFCVRVSFKK
GWGKNYTRMYITQCPCWVEIYLNI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_045583XLOC_045583Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00073440TCONS_00073440Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001132SMAD_dom_Dwarfin-type
IPR003619MAD_homology1_Dwarfin-type
IPR017855SMAD_dom-like
IPR013019MAD_homology_MH1
IPR008984SMAD_FHA_domain
Vocabulary: Cellular Component
TermDefinition
GO:0005622intracellular
GO:0005667transcription factor complex
Vocabulary: Biological Process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0007179transforming growth factor beta receptor signaling pathway
Vocabulary: Molecular Function
TermDefinition
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006355 regulation of transcription, DNA-templated
biological_process GO:0007179 transforming growth factor beta receptor signaling pathway
cellular_component GO:0005622 intracellular
cellular_component GO:0005667 transcription factor complex
molecular_function GO:0005515 protein binding
molecular_function GO:0003700 transcription factor activity, sequence-specific DNA binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001132SMAD domain, Dwarfin-typeSMARTSM00524dwBultra2coord: 241..423
e-value: 7.2E-34
score: 128.5
IPR001132SMAD domain, Dwarfin-typePFAMPF03166MH2coord: 242..423
e-value: 7.9E-37
score: 127.2
IPR001132SMAD domain, Dwarfin-typePROSITEPS51076MH2coord: 243..424
score: 35.763
IPR003619MAD homology 1, Dwarfin-typeSMARTSM00523dwAneu5coord: 52..159
e-value: 3.4E-11
score: 53.2
IPR003619MAD homology 1, Dwarfin-typePFAMPF03165MH1coord: 58..155
e-value: 9.7E-16
score: 57.8
IPR017855SMAD domain-likeGENE3D2.60.200.10coord: 239..424
e-value: 2.2E-41
score: 141.1
IPR013019MAD homology, MH1GENE3D3.90.520.10coord: 23..169
e-value: 1.3E-24
score: 86.0
IPR013019MAD homology, MH1PROSITEPS51075MH1coord: 33..161
score: 19.108
IPR013019MAD homology, MH1SUPERFAMILY56366SMAD MH1 domaincoord: 43..156
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 365..386
IPR008984SMAD/FHA domainSUPERFAMILY49879SMAD/FHA domaincoord: 223..423

Blast
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BLAST of Smad6/7 protein vs. Swiss-Prot (Human)
Match: SMAD6 (Mothers against decapentaplegic homolog 6 OS=Homo sapiens GN=SMAD6 PE=1 SV=2)

HSP 1 Score: 194.126 bits (492), Expect = 1.169e-56
Identity = 120/372 (32.26%), Postives = 185/372 (49.73%), Query Frame = 0 
Query:   55 KELRRKVHSIFKTLTEDQLDILLKTLQANGGIDSECILVNTSTFRHITCRTTSFVPRTLLAKVFRFPNLKDEY-LRCLSCCYNHSSC-DETKVCINPFHSSVVIESESPLPPYSELTPSTALFSESTTTTTLDDDDRHIPTHVALPRTPTHPAFLGYKDLGSTCSSTSSTSSTSSERSHSGPERNWYGGPWCQITYWEEKSRIGSRFDVAKDCVNVFETLPQGSGLDLSMLTRSRPNEASEKVKNDIGYGFQLTREADGIWLYNRSDIVLFAGSPTIQL-GSENLTQPVVKRLPPGNSVLVYDPNLLPDLSTIEKPGLETTEDGMKSSSASKEMRGGTQPFCVRVSFKKGWGKNYTRMYITQCPCWVEIYLN 423
            +EL+   +S+ K L E  LD LL+ +++ GG+   C+LV  +  R          P+ LL ++FR+P+L+    L+ L  C++ ++  D   VC NP+H S +   ESP PPYS L+P         + +TL   +      +      T P             S +S S  +++ SH           WC + YWE ++R+G  + V    V++F  LPQGSG  L  L   + +E+  + ++ IG+G  L++E DG+W YNR +  +F  SPT+   G   L   VV+++PPG S+ V+D          E+ GL+   +            G   P  VR+SF KGWG  Y+R +IT CPCW+EI LN
Sbjct:  170 QELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLR---LGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLI-----TAPGEF----------SDASMSPDATKPSH-----------WCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRAL---VVRKVPPGYSIKVFD---------FERSGLQHAPE-------PDAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLN 493
The following BLAST results are available for this feature:
BLAST of Smad6/7 protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
SMAD61.169e-5632.26Mothers against decapentaplegic homolog 6 OS=Homo ... [more]
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