TCONS_00066576-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00066576-protein
Unique Name	TCONS_00066576-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	738

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00066576-protein ID=TCONS_00066576-protein|Name=TCONS_00066576-protein|organism=Clytia hemisphaerica|type=polypeptide|length=738bp
MRQLRMDDSHSSSKSRTRTGTSSGDDVYVGKYKLIKTIGKGNFAKVKLAK
HLPTGREVAIKIIDKTQLNQTSLQKLFREVRIMKFLDHPNIVKLYEVIET
DKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSSVQYCHQKHV
IHRDLKAENLLLDADMNIKIADFGFSNEFSPGNKLDTFCGSPPYAAPELF
QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF
YMSTDCEALLKKFLVLNPEKRASLETIMTDKWMNIGYENEELKPHIEPKP
DLNDTKRIDVMVKMGFTMGEIQEALKSNKYDEVMATYLLLDETRLTSSDS
IHIDATFIKNANNENSTSRSTRKSGKENKRYPESSRSERAPLINDKSSTT
NGDRSSRSTGRTTDQTGKNPNVADIPDTETLDKTRNSSKGLQRQKSAPSG
PQSRRHTYGQDRAPKNATSVPEKATGSAGQTNGERDSDLPQASKSKQKNM
NDRLSPTRISLPPINKNERRHDHEFGRPTTAPGTGPLDIGASRNNKLRST
YHGSTGQRKAKVPEERSVDTNSAVASGQRTPWLSKLKSRFSTRMSRENLL
SKFRRRRQSNVGTGDSSPSPPTTPPSTNSFGPGFDRIKPRSLRFTWSMKT
TSNLDAESVIHEMKRVLDLNMCDYECRDKYLLYCGHRSTKNNNTLVQWEM
EVCKLPRLHLNGVRMKRIQGPVIDFRNITSKISNEMNL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_041634	XLOC_041634	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00066576	TCONS_00066576	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR015940	UBA
IPR000719	Prot_kinase_dom
IPR001772	KA1_dom
IPR017441	Protein_kinase_ATP_BS
IPR008271	Ser/Thr_kinase_AS
IPR011009	Kinase-like_dom
IPR028375	KA1/Ssp2_C

Vocabulary: **Molecular Function**
Term	Definition
GO:0004672	protein kinase activity
GO:0005524	ATP binding

Vocabulary: **Biological Process**
Term	Definition
GO:0006468	protein phosphorylation

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006468	protein phosphorylation
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004672	protein kinase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR015940	Ubiquitin-associated domain	SMART	SM00165	uba_6	coord: 304..341 e-value: 1.7E-5 score: 34.2
IPR015940	Ubiquitin-associated domain	PROSITE	PS50030	UBA	coord: 301..342 score: 11.101
IPR000719	Protein kinase domain	SMART	SM00220	serkin_6	coord: 32..283 e-value: 1.7E-107 score: 373.1
IPR000719	Protein kinase domain	PFAM	PF00069	Pkinase	coord: 32..283 e-value: 4.3E-76 score: 255.7
IPR000719	Protein kinase domain	PROSITE	PS50011	PROTEIN_KINASE_DOM	coord: 32..283 score: 53.389
IPR001772	Kinase associated domain 1 (KA1)	PFAM	PF02149	KA1	coord: 695..738 e-value: 2.2E-17 score: 62.5
IPR001772	Kinase associated domain 1 (KA1)	PROSITE	PS50032	KA1	coord: 689..738 score: 16.392
None	No IPR available	GENE3D	1.10.510.10		coord: 126..300 e-value: 2.2E-57 score: 192.8
None	No IPR available	GENE3D	1.10.8.10		coord: 301..342 e-value: 3.9E-18 score: 64.6
None	No IPR available	GENE3D	3.30.200.20		coord: 23..125 e-value: 2.2E-36 score: 123.7
None	No IPR available	GENE3D	3.30.310.80		coord: 628..738 e-value: 2.6E-24 score: 84.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 363..580
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 594..635
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..23
None	No IPR available	CDD	cd14072	STKc_MARK	coord: 31..283 e-value: 0.0 score: 579.09
None	No IPR available	CDD	cd14337	UBA_MARK_Par1	coord: 303..342 e-value: 1.33395E-15 score: 71.0096
IPR017441	Protein kinase, ATP binding site	PROSITE	PS00107	PROTEIN_KINASE_ATP	coord: 38..61
IPR008271	Serine/threonine-protein kinase, active site	PROSITE	PS00108	PROTEIN_KINASE_ST	coord: 150..162
IPR011009	Protein kinase-like domain	SUPERFAMILY	56112	Protein kinase-like (PK-like)	coord: 28..284
IPR028375	KA1 domain/Ssp2, C-terminal	SUPERFAMILY	103243	KA1-like	coord: 633..738

Blast

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BLAST of TCONS_00066576-protein vs. Swiss-Prot (Human)
Match: MARK2 (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2)

HSP 1 Score: 710.294 bits (1832), Expect = 0.000e+0
Identity = 398/790 (50.38%), Postives = 501/790 (63.42%), Query Frame = 0

Query:    8 DSHSSSKS---RTRTGTSSGDDV-YVGKYKLIKTIGKGNFAKVKLAKHLPTGREVAIKIIDKTQLNQTSLQKLFREVRIMKFLDHPNIVKLYEVIETDKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSSVQYCHQKHVIHRDLKAENLLLDADMNIKIADFGFSNEFSPGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEALLKKFLVLNPEKRASLETIMTDKWMNIGYENEELKPHIEPKPDLNDTKRIDVMVKMGFTMGEIQEALKSNKYDEVMATYLLLD-ETRLTSSDSIHIDATFIKNANNENSTSRSTR-----KSGKENKRYPESSRSERAPLINDKSSTTNGDRSS-------RSTGRTTDQTGKNPNVADIPDTETLDKTRNSSKGLQRQKSAPSGPQSRRHTYGQDRAPKNATSVPEKATGSAGQTNGERDSDLPQAS---------------KSKQKNMNDRLSPTRIS-LPPINKNERRHDHEFGRPTTAP----------------GTGPLDIGASRNNKLRSTYHGSTGQ-RKAKVPEERSVDTNSAVASGQ---RTPWLSKLKSRFSTRMSRENLLSKFRRRRQSNVGTGDSSPSPPTTPPSTNSFGPG------FDRIKPRSLRFTWSMKTTSNLDAESVIHEMKRVLDLNMCDYECRDKYLLYCGHRSTKNNNTLVQWEMEVCKLPRLHLNGVRMKRIQGPVIDFRNITSKISNEMNL 738
            DS  SSKS   R R   +S D+  ++G Y+L+KTIGKGNFAKVKLA+H+ TG+EVA+KIIDKTQLN +SLQKLFREVRIMK L+HPNIVKL+EVIET+KTLYL+MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS+VQYCHQK ++HRDLKAENLLLDADMNIKIADFGFSNEF+ GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE LLKKFL+LNP KR +LE IM D+WMN+G+E++ELKP++EP PD  D +R ++MV MG+T  EIQ++L   +Y+EVMATYLLL  ++     D+I +      +  N ++ S S +      +  + +R+ + +     P  N  S  T  + +        R +GR    T K P  + +P             GL+R+K+ P+   +   +   +R+ +N+  +   + G A   NG+    +P +                +  QK+M+  + P + S LPP   N      E  RP+TAP                G  P      R    RST+H   GQ R+ +  +        A  SG    R      + S+F+++  R NL  +F RR   N+   +S     T  P     G        F   KPRSLRFTWSMKTTS+++   ++ E+++VLD N C  E  +KY+L C H  T  +   VQWEMEVCKLPRL LNGVR KRI G  + F+NI SKI+NE+ L
Sbjct:   25 DSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVP-ASPLP-------------GLERKKTTPTPSTNSVLSTSTNRS-RNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESN-----CEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHA--GQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARR---NLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMH-GTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL 788

The following BLAST results are available for this feature:

BLAST of TCONS_00066576-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00066576-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
MARK2	0.000e+0	50.38	Serine/threonine-protein kinase MARK2 OS=Homo sapi...	[more]

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TCONS_00066576-protein (polypeptide) - C. hemisphaerica

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