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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00066576-protein ID=TCONS_00066576-protein|Name=TCONS_00066576-protein|organism=Clytia hemisphaerica|type=polypeptide|length=738bp
MRQLRMDDSHSSSKSRTRTGTSSGDDVYVGKYKLIKTIGKGNFAKVKLAK
HLPTGREVAIKIIDKTQLNQTSLQKLFREVRIMKFLDHPNIVKLYEVIET
DKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSSVQYCHQKHV
IHRDLKAENLLLDADMNIKIADFGFSNEFSPGNKLDTFCGSPPYAAPELF
QGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPF
YMSTDCEALLKKFLVLNPEKRASLETIMTDKWMNIGYENEELKPHIEPKP
DLNDTKRIDVMVKMGFTMGEIQEALKSNKYDEVMATYLLLDETRLTSSDS
IHIDATFIKNANNENSTSRSTRKSGKENKRYPESSRSERAPLINDKSSTT
NGDRSSRSTGRTTDQTGKNPNVADIPDTETLDKTRNSSKGLQRQKSAPSG
PQSRRHTYGQDRAPKNATSVPEKATGSAGQTNGERDSDLPQASKSKQKNM
NDRLSPTRISLPPINKNERRHDHEFGRPTTAPGTGPLDIGASRNNKLRST
YHGSTGQRKAKVPEERSVDTNSAVASGQRTPWLSKLKSRFSTRMSRENLL
SKFRRRRQSNVGTGDSSPSPPTTPPSTNSFGPGFDRIKPRSLRFTWSMKT
TSNLDAESVIHEMKRVLDLNMCDYECRDKYLLYCGHRSTKNNNTLVQWEM
EVCKLPRLHLNGVRMKRIQGPVIDFRNITSKISNEMNL Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004672 | protein kinase activity |
| GO:0005524 | ATP binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR015940 | Ubiquitin-associated domain | SMART | SM00165 | uba_6 | coord: 304..341
e-value: 1.7E-5
score: 34.2 |
| IPR015940 | Ubiquitin-associated domain | PROSITE | PS50030 | UBA | coord: 301..342
score: 11.101 |
| IPR000719 | Protein kinase domain | SMART | SM00220 | serkin_6 | coord: 32..283
e-value: 1.7E-107
score: 373.1 |
| IPR000719 | Protein kinase domain | PFAM | PF00069 | Pkinase | coord: 32..283
e-value: 4.3E-76
score: 255.7 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 32..283
score: 53.389 |
| IPR001772 | Kinase associated domain 1 (KA1) | PFAM | PF02149 | KA1 | coord: 695..738
e-value: 2.2E-17
score: 62.5 |
| IPR001772 | Kinase associated domain 1 (KA1) | PROSITE | PS50032 | KA1 | coord: 689..738
score: 16.392 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 126..300
e-value: 2.2E-57
score: 192.8 |
| None | No IPR available | GENE3D | 1.10.8.10 | | coord: 301..342
e-value: 3.9E-18
score: 64.6 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 23..125
e-value: 2.2E-36
score: 123.7 |
| None | No IPR available | GENE3D | 3.30.310.80 | | coord: 628..738
e-value: 2.6E-24
score: 84.6 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 363..580 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 594..635 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1..23 |
| None | No IPR available | CDD | cd14072 | STKc_MARK | coord: 31..283
e-value: 0.0
score: 579.09 |
| None | No IPR available | CDD | cd14337 | UBA_MARK_Par1 | coord: 303..342
e-value: 1.33395E-15
score: 71.0096 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 38..61 |
| IPR008271 | Serine/threonine-protein kinase, active site | PROSITE | PS00108 | PROTEIN_KINASE_ST | coord: 150..162 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 28..284 |
| IPR028375 | KA1 domain/Ssp2, C-terminal | SUPERFAMILY | 103243 | KA1-like | coord: 633..738 |
Blast
BLAST of TCONS_00066576-protein vs. Swiss-Prot (Human)
Match: MARK2 (Serine/threonine-protein kinase MARK2 OS=Homo sapiens GN=MARK2 PE=1 SV=2) HSP 1 Score: 710.294 bits (1832), Expect = 0.000e+0 Identity = 398/790 (50.38%), Postives = 501/790 (63.42%), Query Frame = 0 Query: 8 DSHSSSKS---RTRTGTSSGDDV-YVGKYKLIKTIGKGNFAKVKLAKHLPTGREVAIKIIDKTQLNQTSLQKLFREVRIMKFLDHPNIVKLYEVIETDKTLYLIMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSSVQYCHQKHVIHRDLKAENLLLDADMNIKIADFGFSNEFSPGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCEALLKKFLVLNPEKRASLETIMTDKWMNIGYENEELKPHIEPKPDLNDTKRIDVMVKMGFTMGEIQEALKSNKYDEVMATYLLLD-ETRLTSSDSIHIDATFIKNANNENSTSRSTR-----KSGKENKRYPESSRSERAPLINDKSSTTNGDRSS-------RSTGRTTDQTGKNPNVADIPDTETLDKTRNSSKGLQRQKSAPSGPQSRRHTYGQDRAPKNATSVPEKATGSAGQTNGERDSDLPQAS---------------KSKQKNMNDRLSPTRIS-LPPINKNERRHDHEFGRPTTAP----------------GTGPLDIGASRNNKLRSTYHGSTGQ-RKAKVPEERSVDTNSAVASGQ---RTPWLSKLKSRFSTRMSRENLLSKFRRRRQSNVGTGDSSPSPPTTPPSTNSFGPG------FDRIKPRSLRFTWSMKTTSNLDAESVIHEMKRVLDLNMCDYECRDKYLLYCGHRSTKNNNTLVQWEMEVCKLPRLHLNGVRMKRIQGPVIDFRNITSKISNEMNL 738
DS SSKS R R +S D+ ++G Y+L+KTIGKGNFAKVKLA+H+ TG+EVA+KIIDKTQLN +SLQKLFREVRIMK L+HPNIVKL+EVIET+KTLYL+MEYASGGEVFDYLVAHGRMKEKEARAKFRQIVS+VQYCHQK ++HRDLKAENLLLDADMNIKIADFGFSNEF+ GNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCE LLKKFL+LNP KR +LE IM D+WMN+G+E++ELKP++EP PD D +R ++MV MG+T EIQ++L +Y+EVMATYLLL ++ D+I + + N ++ S S + + + +R+ + + P N S T + + R +GR T K P + +P GL+R+K+ P+ + + +R+ +N+ + + G A NG+ +P + + QK+M+ + P + S LPP N E RP+TAP G P R RST+H GQ R+ + + A SG R + S+F+++ R NL +F RR N+ +S T P G F KPRSLRFTWSMKTTS+++ ++ E+++VLD N C E +KY+L C H T + VQWEMEVCKLPRL LNGVR KRI G + F+NI SKI+NE+ L
Sbjct: 25 DSKPSSKSNMIRGRNSATSADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGKEVAVKIIDKTQLNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKFLILNPSKRGTLEQIMKDRWMNVGHEDDELKPYVEPLPDYKDPRRTELMVSMGYTREEIQDSLVGQRYNEVMATYLLLGYKSSELEGDTITLKPRPSADLTNSSAPSPSHKVQRSVSANPKQRRFSDQAAGPAIPTSNSYSKKTQSNNAENKRPEEDRESGRKASSTAKVP-ASPLP-------------GLERKKTTPTPSTNSVLSTSTNRS-RNSPLLERASLGQASIQNGKDSLTMPGSRASTASASAAVSAARPRQHQKSMSASVHPNKASGLPPTESN-----CEVPRPSTAPQRVPVASPSAHNISSSGGAPDRTNFPRGVSSRSTFHA--GQLRQVRDQQNLPYGVTPASPSGHSQGRRGASGSIFSKFTSKFVRRNLSFRFARR---NLNEPESKDRVETLRPHVVGSGGNDKEKEEFREAKPRSLRFTWSMKTTSSMEPNEMMREIRKVLDANSCQSELHEKYMLLCMH-GTPGHEDFVQWEMEVCKLPRLSLNGVRFKRISGTSMAFKNIASKIANELKL 788
The following BLAST results are available for this feature:
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