TCONS_00057372-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00057372-protein
Unique NameTCONS_00057372-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1370

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00057372-protein ID=TCONS_00057372-protein|Name=TCONS_00057372-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1370bp
MADEIESRKTRFLTLQKRLKEERQFVKHEKEQLRRLNEKALSVSQNLFCS
EWKTRKQWMNIDRLISNKSTPSECSITAKIIDSVSFEDAGSHLNYLDSKY
GEFLSSMRDNPKLVAHILNYCDSQRFQTTTRQLTRLLISTLYGTCAEKKD
ELSVLRILTDLVNLQVLECEDLLQFFCGKRSNDNAFASVFTVFSEMLFSS
KLYLTAALHGTVMQVIVDDGIFLEVDLDKVVGRIPTKVVLEKFGPPQTVE
AKKKMEKHMKLLHDHIINLCKKFLKSMYDKIYCFPQSLRWAIGQLYKGMI
EKLKLPAANAKALISYMLMTYFICPAIINPEPYGINSDADISETARNNLS
LIASILRSQALLECGLKEEKFRSILERLEQGKLISYVSHLLNGASNIAIV
GGRELPEVERSSLMITEHDLKCLVNCLKLVQSHNVASLNPELDELLELLP
PIPRKWVKEISSNRDMTQSMPPNSRLIGDPSPVPPPRHNKLKKAISTSGG
TVSVEKSFMDQLKADLNTMVSSSDVVLIIPLGNDSGEHPGMLSEDKVLGL
KSQLPASNSFDMDTMENDLTKRTHNIMMDALRETLPDVDKNLLDLSNENL
DTISGSSIGSTHNDELLSIKSKQETQKQSDTLDGFDIWANQTDSNTSTLK
DQNQLSDSNSSTLKTTTSNDFFLTEGQNNRPQNLLLDFGDFESSSGPALP
QKKRQYERVSSAFNDEPLIDLAINERRSSEDIKRQESTNSMLGGPSGLNA
ILQNASVASPTEVKVSSEFNPWSPVEQKPDPWRMSDVQEEKEETLPNVQQ
GFENDFKIPIPEKKNQSPVTSPNSSVGSNYAEYAERVKKSPALKKKFGID
LPSLGSKENDDKTPRKKSQGAWLKDKLSTIGRLRTGNQNTGSSIKKSDSL
GNIVNSPTEESASTKQPTSPRGTPMEAAERGKRKSLSFIHAQSSTDGEEE
SSEDIMEKYRKIATLGNSSNTSSSNHNTNNFDPSLDTLPSSTEIGEPLIR
VEEDRIVFDEEFKFEDAKRKLRTVFCTADQTNLPSDARSFDQLLLTMLQA
KLAEAINLQDRFAVAQLHETLRSIKQLPNGSCEKLIERLEQDYEQRSKYI
SYLIKSKQGLLSTISHMEQITAKMQRDKIICSRYFTTLSVRLFLETPERK
QDLMQFAYRFASNKMLDEKSTLLTDFLNDMHSNLIKESTWSHCTDDQLED
AQVATERALMSKIFKEAFYPNGLTDVDNDRIFHQHIKSLSTVISLSHPAL
QIPKMYQKEAPWPSAQTELLMVNAYKTAADKLACIHRCCVTIMNLLSMAS
EKSTPGADDFLPVLVYVVIRANPPNLLSTKQYVNTFYESRLSGEEYYCWM
QFCSAIEFIKTMKAGLAPVK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_036147XLOC_036147Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00057372TCONS_00057372Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR003123VPS9
IPR001936RasGAP_dom
IPR008936Rho_GTPase_activation_prot
Vocabulary: Biological Process
TermDefinition
GO:0043087regulation of GTPase activity
GO:0007165signal transduction
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0043087 regulation of GTPase activity
biological_process GO:0007165 signal transduction
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 16..46
NoneNo IPR availableGENE3D1.10.506.10coord: 200..375
e-value: 5.2E-19
score: 68.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 808..828
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 966..990
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 643..665
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 841..954
NoneNo IPR availableSUPERFAMILY109993VPS9 domaincoord: 1151..1364
IPR003123VPS9 domainSMARTSM00167vps9_2coord: 1261..1370
e-value: 3.8E-18
score: 76.3
IPR003123VPS9 domainPFAMPF02204VPS9coord: 1262..1363
e-value: 9.7E-28
score: 96.3
IPR003123VPS9 domainPROSITEPS51205VPS9coord: 1226..1368
score: 33.114
IPR001936Ras GTPase-activating proteinPFAMPF00616RasGAPcoord: 189..357
e-value: 2.3E-18
score: 66.6
IPR001936Ras GTPase-activating proteinPROSITEPS50018RAS_GTPASE_ACTIV_2coord: 154..361
score: 16.935
IPR008936Rho GTPase activation proteinSUPERFAMILY48350GTPase activation domain, GAPcoord: 99..369

Blast
BLAST of TCONS_00057372-protein vs. Swiss-Prot (Human)
Match: GAPD1 (GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens GN=GAPVD1 PE=1 SV=2)

HSP 1 Score: 366.311 bits (939), Expect = 3.478e-105
Identity = 181/409 (44.25%), Postives = 270/409 (66.01%), Query Frame = 0
Query:  966 GNSSNTSSSNHNTNNFDPSLDTLP-SSTEIGEPLIRVEEDRIVFDEEFKFEDAKRKLRTVFCTAD-----------QTNLPSDARSFDQLLLTMLQAKLAEAINLQDRFAVAQLHETLRSIKQLPNGSCEKLIERLEQDYEQRSKYISYLIKSKQGLLSTISHMEQITAKMQRDKIICSRYFTTLSVRLFLETPERKQDLMQFAYRFASNKMLDEKSTLLTDFLNDMHSNLIKESTWSHCTDDQLEDAQVATERALMSKIFKEAFYPNGLTDVDNDRIFHQHIKSLSTVISLSHPALQIPKMYQKEAPWPSAQTELLMVNAYKTAADKLACIHRCCVTIMNLLSMASEKSTPGADDFLPVLVYVVIRANPPNLLSTKQYVNTFYESRLSGEEYYCWMQFCSAIEFIKTM 1362
            G S++ S  +    N   S D LP S+++   P           D  F + DAK+KLR   C+AD           +  LP      D  ++  L+ ++AEAINLQD+  +AQL ET+R + +  N +C KL+  + +DY +R+ YI+YL + +QGL +T +H+E++  ++ RDK + +RYFTT+ VRL LE+ E+K  + +F   F      D+K+  + DFL  ++  + ++  W + +++QL+DAQ+A ER++M++IFK AFYPN   D+  D++ H+HI+ LS V++ +H ALQIP++Y +EAPWPSAQ+E+  ++AYKT  DK+ CI R C TIMNLLS+A+E S PGADDF+PVLV+V+I+ANPP LLST QY+++FY S LSGEE Y WMQF +A+EFIKT+
Sbjct: 1080 GESAHDSPRDEALQNI--SADDLPDSASQAAHPQ----------DSAFSYRDAKKKLRLALCSADSVAFPVLTHSTRNGLPDHTDPEDNEIVCFLKVQIAEAINLQDKNLMAQLQETMRCVCRFDNRTCRKLLASIAEDYRKRAPYIAYLTRCRQGLQTTQAHLERLLQRVLRDKEVANRYFTTVCVRLLLESKEKK--IREFIQDFQKLTAADDKTAQVEDFLQFLYGAMAQDVIWQNASEEQLQDAQLAIERSVMNRIFKLAFYPNQDGDILRDQVLHEHIQRLSKVVTANHRALQIPEVYLREAPWPSAQSEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEDSVPGADDFVPVLVFVLIKANPPCLLSTVQYISSFYASCLSGEESYWWMQFTAAVEFIKTI 1474          

HSP 2 Score: 268.085 bits (684), Expect = 7.985e-73
Identity = 202/683 (29.58%), Postives = 349/683 (51.10%), Query Frame = 0
Query:   14 TLQKRLKEERQFVKHEKEQLRRLNEKALSVSQNLFCSEWKTRKQWMNIDRLI--SNKSTPSECSITAKIIDSVSFEDAGSHLNYLDSKYGEFLSSMRDNPKLVAHILNYCDSQRFQTTTRQLTRLLISTLYGTCAEKKDELSVLRILTDLVNLQVLECEDLLQFFCGKRSNDNAFASVFTVFSEMLFSSKLYLTAALHGTVMQVIVDDGIFLEVDLDKVVGRIPTKVVLEKFGPPQTVEAKKKMEKHMKLLHDHIINLCKKFLKSMYDKIYCFPQSLRWAIGQLYKGMIEKLKLPAANAKALISYMLMTYFICPAIINPEPYGINSDADISETARNNLSLIASILRSQALLECGLKEEKFRSILERLEQGKLISYVSHLLNGA-------SNIAIVGGRELPEVERSSLMITEHDLKCLVNCLKLVQSHN-VASLNPELDELLELLPPI-PRKWVKEISSNRDMTQSMPPNSRLIGDPSPVPPPRHNKLKKAISTSGGTVSVEKSFMDQLKADLNTMVS-SSDVVLIIPLGNDSGEHPGMLSEDKVLGLKSQLPASNSFDMDTMENDLTKRTHNIM--------MDALRETLPDVDKNL--LDLSNENLDTISGSSIGSTHNDELLSIKSKQETQKQS--DTLDGFDIWANQTDSNTSTLKDQNQLSDSNSSTLKTTT-SNDF 671
            TL   LK+ER +V  EK+ ++RLN   L  ++ L+ + W  ++Q +N+DRLI  S +++P+EC   AKI++   F D    L + ++ YGEFLS +R+NP+L+A  L     +  Q  T+ +   + ++LYG C  ++DE  +L++L  L+  ++ E ++  +     R    AF+ +F +FSE LFS+KL+LTA LH  +MQ++V+D   LE D +K++ R       + FG   +   ++K+++ ++     ++ L  KF+  +    YCFP SLRW + Q+YK +    +L     +A+ + +L+  FICPA++NPE YGI SDA I+E AR NL  +  +L+  A+      + + +S L + ++  + +++  ++ G        S++ ++ G     + R+ + IT   L  LVN +K V S + +      LD LL  LPP  P K     SS+ +MT   P N+  +  P+  P  + N+L  A  +   T  +    MD   +   T+     + VL+I LG      PGM+SE++VL +  QL      D+   EN L  +    +        ++ + E   +   ++  LDL  E++  +     GS   + L  ++ +Q T + +  D L  F+I       +   L D   +S++ S T  T    +DF
Sbjct:    8 TLAHHLKQERLYVNSEKQLIQRLNADVLKTAEKLYRTAWIAKQQRINLDRLIITSAEASPAECCQHAKILEDTQFVDGYKQLGFQETAYGEFLSRLRENPRLIASSL-VAGEKLNQENTQSVIYTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLL---RRGTCAFSILFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPNKLIERFSPSQQEKLFGEKGSDRFRQKVQEMVESNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMYKTLSCVDRLEVGEVRAMCTDLLLACFICPAVVNPEQYGIISDAPINEVARFNLMQVGRLLQQLAMTGSEEGDPRTKSSLGKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEG-----LSRTVVYITYSQLITLVNFMKSVMSGDQLREDRMALDNLLANLPPAKPGK-----SSSLEMT---PYNTPQLS-PATTPANKKNRLPIATRSRSRTNMLMDLHMDHEGSSQETIQEVQPEEVLVISLGTGPQLTPGMMSENEVLNM--QLSDGGQGDVPVDENKLHGKPDKTLRFSLCSDNLEGISEGPSNRSNSVSSLDLEGESVSELGAGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEI------RDMMGLTDDRDISETVSETWSTDVLGSDF 664          
The following BLAST results are available for this feature:
BLAST of TCONS_00057372-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GAPD13.478e-10544.25GTPase-activating protein and VPS9 domain-containi... [more]
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