Putative disulfide isomerase (polypeptide) - C. hemisphaerica

Overview
NamePutative disulfide isomerase
Unique NameTCONS_00056988-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length215

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00056988-protein ID=TCONS_00056988-protein|Name=Putative disulfide isomerase|organism=Clytia hemisphaerica|type=polypeptide|length=215bp
MKLLILISIISFVAGESLVLTKDNFDQHVMDPSKNVLVEFYAPWCGHCKN
LAPVYEKVAETFKNEPKCIVAKVDADSEKEIGSRFSVSGFPTIKFFSKTN
KDGEEYSSGRSEQNFIDFLNEKCGTNRVSGGGIDDKAGRIDAFDTAAETF
MKNPDERESLIAQLADTAAGESDPDYKKSGEYYVKVMKKIQEKGNEYVTK
ELARLQRMLGEIISL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_035885XLOC_035885Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00056988TCONS_00056988Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR013766Thioredoxin_domain
IPR005788Disulphide_isomerase
IPR011679ERp29_C
IPR017937Thioredoxin_CS
IPR012336Thioredoxin-like_fold
Vocabulary: Biological Process
TermDefinition
GO:0045454cell redox homeostasis
Vocabulary: Molecular Function
TermDefinition
GO:0016853isomerase activity
Vocabulary: Cellular Component
TermDefinition
GO:0005783endoplasmic reticulum
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0045454 cell redox homeostasis
cellular_component GO:0005783 endoplasmic reticulum
molecular_function GO:0016853 isomerase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00421THIOREDOXINcoord: 36..44
score: 65.93
coord: 86..97
score: 41.3
coord: 44..53
score: 65.83
NoneNo IPR availableGENE3D3.40.30.10coord: 16..124
e-value: 3.3E-32
score: 110.5
NoneNo IPR availableSFLDSFLDG00345PDI-likecoord: 19..122
e-value: 5.0E-33
score: 108.0
NoneNo IPR availableCDDcd02998PDI_a_ERp38coord: 18..119
e-value: 5.92109E-52
score: 164.345
IPR013766Thioredoxin domainPFAMPF00085Thioredoxincoord: 18..121
e-value: 2.8E-32
score: 110.6
IPR013766Thioredoxin domainPROSITEPS51352THIOREDOXIN_2coord: 3..166
score: 15.043
IPR005788Disulphide isomeraseTIGRFAMTIGR01126TIGR01126coord: 20..122
e-value: 1.4E-40
score: 135.8
IPR011679Endoplasmic reticulum resident protein 29, C-terminalPFAMPF07749ERp29coord: 138..209
e-value: 9.8E-18
score: 64.7
IPR011679Endoplasmic reticulum resident protein 29, C-terminalGENE3D1.20.1150.12coord: 137..214
e-value: 8.9E-20
score: 70.9
IPR011679Endoplasmic reticulum resident protein 29, C-terminalSUPERFAMILY47933ERP29 C domain-likecoord: 137..210
IPR017937Thioredoxin, conserved sitePROSITEPS00194THIOREDOXIN_1coord: 37..55
IPR012336Thioredoxin-like foldSUPERFAMILY52833Thioredoxin-likecoord: 17..125

Blast
[Close]
BLAST of Putative disulfide isomerase vs. Swiss-Prot (Human)
Match: PDIA4 (Protein disulfide-isomerase A4 OS=Homo sapiens GN=PDIA4 PE=1 SV=2)

HSP 1 Score: 105.531 bits (262), Expect = 2.449e-26
Identity = 54/109 (49.54%), Postives = 72/109 (66.06%), Query Frame = 0 
Query:   17 SLVLTKDNFDQHVMDPSKNVLVEFYAPWCGHCKNLAPVYEKVA-ETFKNEPKCIVAKVDADSEKEIGSRFSVSGFPTIKFFSKTNKDGEEYSSGRSEQNFIDFLNEKCG 124
            +LVLTK+NFD+ V D +  +LVEFYAPWCGHCK LAP YEK A E  K  P   +AKVDA +E ++  RF VSG+PT+K F K      +Y+  R +   +D++ E+ G
Sbjct:  179 TLVLTKENFDEVVND-ADIILVEFYAPWCGHCKKLAPEYEKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRP--YDYNGPREKYGIVDYMIEQSG 284

HSP 2 Score: 94.7449 bits (234), Expect = 1.647e-22
Identity = 48/100 (48.00%), Postives = 60/100 (60.00%), Query Frame = 0 
Query:   18 LVLTKDNFDQHVMDPSKNVLVEFYAPWCGHCKNLAPVYEKVAETFKN-EPKCIVAKVDADSEKEIGSRFSVSGFPTIKFFSKTNKDGEEYSSGRSEQNFI 116
            LVL   NFD  V D    VL+EFYAPWCGHCK  AP YEK+A   K+ +P   VAK+DA S   + SRF VSG+PTIK   K      +Y   R+++  +
Sbjct:   65 LVLNDANFDNFVAD-KDTVLLEFYAPWCGHCKQFAPEYEKIANILKDKDPPIPVAKIDATSASVLASRFDVSGYPTIKILKKGQ--AVDYEGSRTQEEIV 161

HSP 3 Score: 92.4337 bits (228), Expect = 1.067e-21
Identity = 41/87 (47.13%), Postives = 54/87 (62.07%), Query Frame = 0 
Query:   15 GESLVLTKDNFDQHVMDPSKNVLVEFYAPWCGHCKNLAPVYEKVAETFKNEPKCIVAKVDADSEKEIGSRFSVSGFPTIKFFSKTNK 101
            G   V+    FD  VMDP K+VL+EFYAPWCGHCK L PVY  +A+ +K +   ++AK+DA +      R+ V GFPTI F    +K
Sbjct:  525 GPVKVVVGKTFDSIVMDPKKDVLIEFYAPWCGHCKQLEPVYNSLAKKYKGQKGLVIAKMDATANDVPSDRYKVEGFPTIYFAPSGDK 611
The following BLAST results are available for this feature:
BLAST of Putative disulfide isomerase vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
PDIA42.449e-2649.54Protein disulfide-isomerase A4 OS=Homo sapiens GN=... [more]
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