TCONS_00021872-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00021872-protein
Unique Name	TCONS_00021872-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	777

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00021872-protein ID=TCONS_00021872-protein|Name=TCONS_00021872-protein|organism=Clytia hemisphaerica|type=polypeptide|length=777bp
VNKIVIQNEKDIVIPLFTSIFISFTSGRHMVANFIQSYKVMYKDENNAWR
YYTLSGASAPKIFKGNTAPNQKTLSKLEYKIQARFIKLFPERFYSNACLR
FELYGCVNETEPTTTTAPTTTTMPTTTTQPTTTPTICPEFRCGNGSCIPN
LWVCDGKQQCSDGGDENVCNGNCSADQFHCRSGYCLPKQFRCDQDNDCFH
GDDEMHCDNTTCNIFQFRCNDGSCIHLSQKCDGRVDCSTGEDEKSCPTTT
TSPATTTTPRTTTTTTARPVCNGFKCRYGGKCLSNDLICDGTRDCGGWGE
DEECCNTKTQYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDEFNCTHTT
TGPATTTRYSTNIFTEPTATTKHGGQGGGTTTRGCPRNSTCLCENTCDSL
AEKPDGCLSFYCIDDCSCPTGFTYDNVTKRCERDLDCPCVRNGTIYKTGS
VLDGGNCTKCICTQNGFKCAKICPIKSCGLGEEMVYPKDDCCYCEKKISC
RKDQYLTDCSCERNCTSNLTTCDPDTCSIGCACPDGTFDNGTNCVQKKKC
YCVDEDGVKRKPNSRWGSGDCDSCKCTNGKIKCGKVCNHITCPPNFELFT
PPDGCCMCMPKKTTAPPSVSTTTTTTTKSTTQSTRPTTQSTAQSTRPNTY
STKHSTLFTTSTTLQQTTSSPTTTPSQPNNCTKTEEIETYTDKHQCSGQV
TKTYCQGGCLSTIISDFILGIGIQKCTCCKPIGIFNTTISLQCQNGNSKI
FTYQRFRSCSCQPCDNSPFDDVTLFNP

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_012271	XLOC_012271	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00021872	TCONS_00021872	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR002172	LDrepeatLR_classA_rpt
IPR006207	Cys_knot_C
IPR001007	VWF_dom
IPR008979	Galactose-bd-like
IPR000421	FA58C
IPR023415	LDLR_class-A_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0005515	protein binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
molecular_function	GO:0005515	protein binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PRINTS	PR00261	LDLRECEPTOR	coord: 145..166 score: 51.11 coord: 183..204 score: 45.01 coord: 222..243 score: 49.67 coord: 280..301 score: 29.05 coord: 322..343 score: 55.32
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	SMART	SM00192	LDLa_2	coord: 211..248 e-value: 1.0E-12 score: 58.3 coord: 136..171 e-value: 4.1E-11 score: 52.9 coord: 172..209 e-value: 7.1E-9 score: 45.5 coord: 308..348 e-value: 5.2E-7 score: 39.3 coord: 270..307 e-value: 0.0073 score: 23.3
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PFAM	PF00057	Ldl_recept_a	coord: 321..346 e-value: 1.8E-7 score: 31.2 coord: 139..169 e-value: 4.5E-10 score: 39.5 coord: 172..207 e-value: 3.0E-9 score: 36.8 coord: 210..246 e-value: 4.0E-10 score: 39.7
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 304..347 score: 12.85
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 211..247 score: 12.75
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 136..170 score: 12.925
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 270..305 score: 9.613
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	PROSITE	PS50068	LDLRA_2	coord: 172..208 score: 12.688
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	SUPERFAMILY	57424	LDL receptor-like module	coord: 211..250
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	SUPERFAMILY	57424	LDL receptor-like module	coord: 172..207
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	SUPERFAMILY	57424	LDL receptor-like module	coord: 310..349
IPR002172	Low-density lipoprotein (LDL) receptor class A repeat	SUPERFAMILY	57424	LDL receptor-like module	coord: 134..169
IPR006207	Cystine knot, C-terminal	SMART	SM00041	CT_3	coord: 684..765 e-value: 6.9E-6 score: 35.6
IPR006207	Cystine knot, C-terminal	PROSITE	PS01185	CTCK_1	coord: 728..764
IPR006207	Cystine knot, C-terminal	PROSITE	PS01225	CTCK_2	coord: 681..765 score: 11.609
IPR001007	VWFC domain	SMART	SM00214	vwc	coord: 552..608 e-value: 0.0041 score: 26.3 coord: 439..494 e-value: 0.063 score: 22.4
None	No IPR available	GENE3D	4.10.1220.10		coord: 322..356 e-value: 6.4E-12 score: 44.8
None	No IPR available	GENE3D	2.10.70.10		coord: 444..472 e-value: 2.3E-4 score: 20.8
None	No IPR available	GENE3D	2.10.25.10		coord: 495..566 e-value: 3.2E-6 score: 26.7 coord: 368..443 e-value: 4.0E-6 score: 26.4
None	No IPR available	GENE3D	4.10.400.10		coord: 129..170 e-value: 8.4E-11 score: 41.6
None	No IPR available	GENE3D	4.10.400.10		coord: 261..310 e-value: 9.0E-5 score: 21.8 coord: 211..254 e-value: 8.0E-12 score: 44.3
None	No IPR available	GENE3D	4.10.400.10		coord: 171..210 e-value: 1.9E-10 score: 40.3
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 614..653
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 237..262
None	No IPR available	CDD	cd00112	LDLa	coord: 212..246 e-value: 1.69574E-6 score: 44.8902
None	No IPR available	CDD	cd00112	LDLa	coord: 322..346 e-value: 2.62097E-4 score: 38.3418
None	No IPR available	CDD	cd00112	LDLa	coord: 173..207 e-value: 1.30459E-5 score: 42.1938
None	No IPR available	CDD	cd00112	LDLa	coord: 139..169 e-value: 1.69574E-6 score: 44.8902
IPR008979	Galactose-binding domain-like	GENE3D	2.60.120.260		coord: 1..108 e-value: 8.7E-13 score: 48.1
IPR008979	Galactose-binding domain-like	SUPERFAMILY	49785	Galactose-binding domain-like	coord: 27..106
IPR000421	Coagulation factor 5/8 C-terminal domain	PROSITE	PS01286	FA58C_2	coord: 90..106
IPR000421	Coagulation factor 5/8 C-terminal domain	PROSITE	PS50022	FA58C_3	coord: 1..106 score: 17.213
IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site	PROSITE	PS01209	LDLRA_1	coord: 324..346
IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site	PROSITE	PS01209	LDLRA_1	coord: 282..305
IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site	PROSITE	PS01209	LDLRA_1	coord: 185..207
IPR023415	Low-density lipoprotein (LDL) receptor class A, conserved site	PROSITE	PS01209	LDLRA_1	coord: 224..246

Blast

[Close]

BLAST of TCONS_00021872-protein vs. Swiss-Prot (Human)
Match: LRP1 (Prolow-density lipoprotein receptor-related protein 1 OS=Homo sapiens GN=LRP1 PE=1 SV=2)

HSP 1 Score: 131.339 bits (329), Expect = 5.054e-31
Identity = 82/222 (36.94%), Postives = 112/222 (50.45%), Query Frame = 0

Query:  139 EFRCGNGSCIPNLWVCDGKQQCSDGGDENVCNGNCSADQFHCRSGYCLPKQFRCDQDNDCFHGDDEMHCDN--TTCNIFQFRCNDGSCIHLSQKCDGRVDCSTGEDE--KSCPTTTTSPATTTTPRTTTTTTARPVCNGFKCRYGGKCLSNDLICDGTRDCGGWGEDEEC---------CNTKTQYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDEFNCT 347
            EF C NG CI   W CDG   C+DG DE  C   C  DQF C+SG+C+P ++RCD D DC  G DE  C     TC + +F+CN+  C  L+ KCDG  DC    DE  + C      P              RP    F+C+    CL     CDGT +CG   ++E+C         C  K ++ C ++      +C+ +S RC+ ++DCGD SDE +C+
Sbjct: 3579 EFSCANGRCIAGRWKCDGDHDCADGSDEKDCTPRCDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDENPEECARFVCPP-------------NRP----FRCKNDRVCLWIGRQCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQ------RCLSSSLRCNMFDDCGDGSDEEDCS 3777

HSP 2 Score: 115.161 bits (287), Expect = 6.376e-26
Identity = 80/217 (36.87%), Postives = 102/217 (47.00%), Query Frame = 0

Query:  139 EFRCGNGSCIPNLWVCDGKQQCSDGGDENVCNGNCSADQFHCRSGYCLPKQFRCDQDNDCFHGDDEMHCDNTT--------CNIFQFRCN-DGSCIHLSQKCDGRVDCSTGEDEKSCPTTTTSPATTTTPRTTTTTTARPVCN---GFKCRYGGKCLSNDLICDGTRDCGGWGEDEECCNTKTQYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDE 343
            +F C NG CI   W CD    C D  DE  C+ +CS+ QF C SG C+P+ + CD DNDC    DE H + T         C+  +F+C  DG CI L  +CDG  DC    DEKSC   T                   VC+    F C+   +C+S   +CDG  DC     DEE C +      SH    +   C+   + CDG +DCGD SDE
Sbjct:  981 QFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVTH------------------VCDPSVKFGCKDSARCISKAWVCDGDNDCED-NSDEENCESLACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDE 1178

HSP 3 Score: 108.997 bits (271), Expect = 4.552e-24
Identity = 82/240 (34.17%), Postives = 109/240 (45.42%), Query Frame = 0

Query:  139 EFRCGNGSCIPNLWVCDGKQQCSDGGDE--NVCNGNCSADQFHCRSGYCLPKQFRCDQDNDCFHGDDEMHCDNTTCNIFQFRC-NDGSCIHLSQKCDGRVDCSTGEDEKSCPTTTTSPATTT-------TPRTTTTTTARPVCNG----------------FKCRYGGKCLSNDLICDGTRDCG-GWGEDEECCNTKT----QYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDEFNCT 347
            +F C N  CIP  W CD +  C D  DE  +     C   QF C +G C    F CD DNDC    DE +CD   C   QF+C N   CI    +C+G+ +C  GEDE+ CP  T +P            PR           +G                F+C+  G+C+     CDG  DCG G  E +E C+ +T    Q+RC +       +C+    +CD  NDCGD+SDE +CT
Sbjct: 3338 QFVCKNDKCIPFWWKCDTEDDCGDHSDEPPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKN------NRCVPGRWQCDYDNDCGDNSDEESCT 3571

HSP 4 Score: 107.071 bits (266), Expect = 1.836e-23
Identity = 79/215 (36.74%), Postives = 105/215 (48.84%), Query Frame = 0

Query:  139 EFRCGN-GSCIPNLWVCDGKQQCSDGGDE--NVCNGN-CSADQFHCRSGYCLPKQFRCDQDNDCFHGDDEMHCDNTTCNIFQFRCNDGSCIHLSQKCDGRVDCSTGEDEKSCPTTTTSPATTTTPRTTTTTTARPVCNGFKCRYGGKCLSNDLICDGTRDCGGWGEDEECCNTKT------QYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDE 343
            EFRC + G CIP  W CDG+  C DG DE    C+   C   QF C++  C+P +++CD DNDC    DE  C    C+  +F C +G CI    KCDG  DC+ G DEK C           TPR           + F+C+  G C+     CD   DC   G DEE C T        +++C++        C   + +CDG +DCGD+SDE
Sbjct: 3498 EFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC-----------TPRCDM--------DQFQCK-SGHCIPLRWRCDADADCMD-GSDEEACGTGVRTCPLDEFQCNNT------LCKPLAWKCDGEDDCGDNSDE 3685

HSP 5 Score: 105.145 bits (261), Expect = 6.622e-23
Identity = 87/233 (37.34%), Postives = 108/233 (46.35%), Query Frame = 0

Query:  137 CP--EFRCGNGSCIPNLWVCDGKQQCSDGGDENVCNGNCSA-----DQFHCRSGYCLPKQFRCDQDNDCFHGDDE-MHCDNTTC-NIFQFRCNDGSCIHLSQKCDGRVDCSTGEDEKSCPTTTTSPATTTTPRTTTTTTARPVCNGFKCRYGGKCLSNDLICDGTRDCGGWGEDEECCNTKTQYRCSHRP--GAHV--------GKCIQASRRCDGYNDCGDSSDEFNCTHTT 350
            CP   F+C N  CIPN W+CDG   C +  DE+  N  CSA     +QF C SG C+P  + CD D+DC    DE   C   TC  + QF CN+G CI+++ +CD   DC    DE  C  + +S                     FKC   G+C+     CDG  DCG +  DE   N   Q   + RP  G H         G CI    RCDG  DC DSSDE +C   T
Sbjct:  895 CPSDRFKCENNRCIPNRWLCDGDNDCGNSEDES--NATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSTQ-------------------FKCN-SGRCIPEHWTCDGDNDCGDY-SDETHANCTNQ---ATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMDSSDEKSCEGVT 1101

HSP 6 Score: 98.2117 bits (243), Expect = 9.135e-21
Identity = 84/258 (32.56%), Postives = 110/258 (42.64%), Query Frame = 0

Query:  139 EFRCGNGSCIPNLWVCDGKQQCSDGGDE--NVCNGN-CSADQFHCRSGYCLPKQFRCDQDNDCFHGDDEMHCDNTTCNIFQFRCNDGSCIHLSQKCDGRVDCSTGEDEKSCPTTTTS-------PATTTTP--RTTTTTTARPVCNG-------------------------FKCRYGGKCLSNDLICDGTRDCGGWGEDEECCN---TKTQYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDE-FNCTHTTTGPAT 355
            EF C NG CI     CDG   C D  DE  + CN   C      C +G C+     C+  +DC  G DE+ C+ T C + +FRC DG+CI  S +C+  VDC    DE +C  T  S             P  RT+       VC+G                         F C   G+C+     CD   DC   GEDE  CN   ++ Q+ C +       +CI     CDG +DCGD SDE  +C   T GP++
Sbjct: 2529 EFECANGECINFSLTCDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPCNKTACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNCSATDCSSYFRLGVKGVLFQPCERTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACP-SGRCIPMSWTCDKEDDCEH-GEDETHCNKFCSEAQFECQNH------RCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSS 2778

HSP 7 Score: 95.5153 bits (236), Expect = 5.861e-20
Identity = 80/246 (32.52%), Postives = 105/246 (42.68%), Query Frame = 0

Query:  140 FRCGNGSCIPNLWVCDGKQQCSDGGDENVCNGNCSADQFHCRSGYCLPKQFRCDQDNDCFHGDDE-MHCDNTTCNIFQFRC-NDGSCIHLSQKCDGRVDCSTGEDE---KSCPTTTTSPATTTT-------PRTTTTTTARPVCNG----------------FKCRYGGKCLSN-DLICDGTRDCGGWGED----------EECCNTKTQYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDEFNC 346
            F C +G CIP  W CD +  C  G DE  CN  CS  QF C++  C+ KQ+ CD  +DC  G DE  HC+  TC    F C     C+     CDG  DC+ G DE     C   +T              P+       R   +G                F+C   G+CLS+    CDG  DC    ++          E  CN  +Q+ CS       G+C+  +  C+G +DCGDSSDE  C
Sbjct: 2701 FACPSGRCIPMSWTCDKEDDCEHGEDETHCNKFCSEAQFECQNHRCISKQWLCDGSDDCGDGSDEAAHCEGKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDESPECEYPTCGPSEFRCA-NGRCLSSRQWECDGENDCHDQSDEAPKNPHCTSQEHKCNASSQFLCSS------GRCVAEALLCNGQDDCGDSSDERGC 2939

HSP 8 Score: 95.5153 bits (236), Expect = 6.717e-20
Identity = 82/271 (30.26%), Postives = 113/271 (41.70%), Query Frame = 0

Query:  134 PTICPEFRCGNGS-----------------------------------------------CIPNLWVCDGKQQCSDGGDENVC-NGNCSADQFHCR-SGYCLPKQFRCDQDNDCFHGDDE-MHCDNTTCNIFQFRCND-GSCIHLSQKCDGRVDCSTGEDE--KSCPTTTTSPATTTTPRTTTTTTARPVCNGFKCRYGGKCLSNDLICDGTRDCGGWGEDEECCN----TKTQYRCSHRPGAHVGKCIQASRRCDGYNDCGDSSDEFNCT 347
            P  CPEF+C  G                                                CIP ++ C+G+  C DG DE  C    C+ +QF C  +  C+P+ + CD+DNDC  G DE  +C   TC + +FRC D G CI    KCDG  DC  G DE  + C   T  P                    F+C+   +C+     CD   DCG    DEE C     +++++ C++      G+CI    +CDG +DC D SDE +CT
Sbjct: 3366 PPDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDCPEVTCAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQ------------------FRCK-NNRCVPGRWQCDYDNDCGD-NSDEESCTPRPCSESEFSCAN------GRCIAGRWKCDGDHDCADGSDEKDCT 3610

The following BLAST results are available for this feature:

BLAST of TCONS_00021872-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00021872-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
LRP1	5.054e-31	36.94	Prolow-density lipoprotein receptor-related protei...	[more]

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TCONS_00021872-protein (polypeptide) - C. hemisphaerica