alpha-actinin (polypeptide) - C. hemisphaerica

Overview
Namealpha-actinin
Unique NameTCONS_00007545-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length414

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00007545-protein ID=TCONS_00007545-protein|Name=alpha-actinin|organism=Clytia hemisphaerica|type=polypeptide|length=414bp
MADEEHYGYFYGEEEKGLLDPAWERQQKKTFTAWCNSHLRKVNVQIEEIT
EDFRDGLKLMLLLEVISGDRLPKPEKGRLRFHLVSNVNKALDFIVSKGVK
LVGVGAEEIVDGNLKMTLGMIWTIILRFAIQDITVDEFSAKEGLLLWCQR
KTAPYKNVNVQNFHMSFKDGLAFCALIHRHRPELIDYDKLSKDDPMYNLN
YAFDVAEKHLDIPKMLDAEDMVNQVKPDERAVMTYVSCYYHAFSSSQQAE
TAAKRILKALNVNQGNEKAMEDYENLASDLLDWINKKIPEFEDRTTDNSL
ANMQEKLNDFRNYKGKEKPPKVDDKSRLENLFNTLQTKLRLSNRPVYMPA
EGKMISDIDKAWKDLEQAEKDFQDWILSQLRKLERLDHLAQKFKLKCDTH
EAWAHGQDDYXRQD
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_004266XLOC_004266Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00007545TCONS_00007545Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001715CH-domain
IPR002017Spectrin_repeat
IPR001589Actinin_actin-bd_CS
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001715Calponin homology domainSMARTSM00033ch_5coord: 140..239
e-value: 1.1E-24
score: 98.0
coord: 27..127
e-value: 7.3E-23
score: 92.0
IPR001715Calponin homology domainGENE3D1.10.418.10coord: 137..246
e-value: 2.7E-31
score: 107.2
IPR001715Calponin homology domainPFAMPF00307CHcoord: 140..244
e-value: 4.7E-28
score: 97.4
coord: 26..129
e-value: 1.0E-22
score: 80.3
IPR001715Calponin homology domainGENE3D1.10.418.10coord: 22..133
e-value: 3.8E-37
score: 126.3
IPR001715Calponin homology domainPROSITEPS50021CHcoord: 25..129
score: 16.905
IPR001715Calponin homology domainPROSITEPS50021CHcoord: 138..241
score: 16.72
IPR001715Calponin homology domainCDDcd00014CHcoord: 27..129
e-value: 7.0461E-22
score: 88.5219
IPR001715Calponin homology domainCDDcd00014CHcoord: 139..243
e-value: 4.15135E-27
score: 102.774
IPR001715Calponin homology domainSUPERFAMILY47576Calponin-homology domain, CH-domaincoord: 18..241
NoneNo IPR availableGENE3D1.20.58.60coord: 258..384
e-value: 5.6E-20
score: 71.4
NoneNo IPR availableSUPERFAMILY46966Spectrin repeatcoord: 260..383
IPR002017Spectrin repeatPFAMPF00435Spectrincoord: 269..375
e-value: 1.4E-11
score: 44.7
IPR001589Actinin-type actin-binding domain, conserved sitePROSITEPS00019ACTININ_1coord: 27..36
IPR001589Actinin-type actin-binding domain, conserved sitePROSITEPS00020ACTININ_2coord: 101..125

Blast
[Close]
BLAST of alpha-actinin vs. Swiss-Prot (Human)
Match: ACTN2 (Alpha-actinin-2 OS=Homo sapiens GN=ACTN2 PE=1 SV=1)

HSP 1 Score: 618.231 bits (1593), Expect = 0.000e+0
Identity = 283/413 (68.52%), Postives = 347/413 (84.02%), Query Frame = 0 
Query:    6 HYGYFYGEEEKG----------LLDPAWERQQKKTFTAWCNSHLRKVNVQIEEITEDFRDGLKLMLLLEVISGDRLPKPEKGRLRFHLVSNVNKALDFIVSKGVKLVGVGAEEIVDGNLKMTLGMIWTIILRFAIQDITVDEFSAKEGLLLWCQRKTAPYKNVNVQNFHMSFKDGLAFCALIHRHRPELIDYDKLSKDDPMYNLNYAFDVAEKHLDIPKMLDAEDMVNQVKPDERAVMTYVSCYYHAFSSSQQAETAAKRILKALNVNQGNEKAMEDYENLASDLLDWINKKIPEFEDRTTDNSLANMQEKLNDFRNYKGKEKPPKVDDKSRLENLFNTLQTKLRLSNRPVYMPAEGKMISDIDKAWKDLEQAEKDFQDWILSQLRKLERLDHLAQKFKLKCDTHEAWAHGQD 408
             Y Y Y E+E            LLDPAWE+QQ+KTFTAWCNSHLRK   QIE I EDFR+GLKLMLLLEVISG+RLPKP++G++RFH ++NVNKALD+I SKGVKLV +GAEEIVDGN+KMTLGMIWTIILRFAIQDI+V+E SAKEGLLLWCQRKTAPY+NVN+QNFH S+KDGL  CALIHRHRP+LIDY KL+KDDP+ N+N A ++AEKHLDIPKMLDAED+VN  KPDERA+MTYVSC+YHAF+ ++QAETAA RI K L VNQ NE+ ME+YE LAS+LL+WI + IP  E+RT + ++  MQ+KL DFR+Y+ K KPPKV +K +LE  FNTLQTKLR+SNRP +MP+EGKM+SDI  AW+ LEQAEK +++W+L+++R+LERL+HLA+KF+ K  THE WA+G++
Sbjct:    9 QYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKE 421
The following BLAST results are available for this feature:
BLAST of alpha-actinin vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACTN20.000e+068.52Alpha-actinin-2 OS=Homo sapiens GN=ACTN2 PE=1 SV=1[more]
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