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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00004545-protein ID=TCONS_00004545-protein|Name=TCONS_00004545-protein|organism=Clytia hemisphaerica|type=polypeptide|length=819bp MLCSILTMLYLLAGLDMISSYTLFDIKMPNVSPKEDESYLCTGKKLPRTR DRYYAYKFEPNADEKTAHHMLVYACRSLSKRNRHNAYWKCHGTPCSGGQI IYAWAKNAEGLTLPKHVGFPLGDDFDLNYIVQQIHYARPLQDDEYDSSGV KIRLTKYEPQFVASIYLFASNFQIPPNSKGYNVDMACKYRGDSIKPFAFR THAHKHGRSISAYRVRDGVWDQIGIGSPQRPQAFYPIKKEDRLLLKSNDV LVARCTFDTMDETKTISAGSYSSDEMCNFYMMYYTMNKGEDFSVPSGCSS TTHTLDFPKDSMLPFQSSSSNTQPQTTPVASTVKPSSKKPEQKISSTPTD PHSKAVIITTKAPSSTHSGSSAHHSSGLPELDGSWSVEKELRSSFKGQIR SMDVTLDYKLVVLTGVRPANNSLFDGEHFLLESKPIEEKTIYIVNSNDGS LFNSFGANVFYLPSSVRVDHQGHFFITDLGRHQVLKFDPLKKETLQLVLG QEGIPGEDRNHFCSPADVVVDHKNHIYVADGLCNNRIVKFDANGKYLSEF GSGHLKHPQHLAISGHHIYVATQDRHQIYVFDFDGKFIRALSHGLSTNEI SMVYCHAKDSKDELLYIVGKNKVVAINLQKDSSIAWQIKGTGDKVLALSR DHRYLYIGDKDNGDIQRYLLPSSTSKNKGKNNFPWSPIDQIPSSTKPSTN NNSSRQVDILPKTPYDDDDITVIPAVVVVAVLATPIILVFVALIIQHVRL KHRVKRAAQKRTLDNYTKTGICTCCWSTPKYYYDSQKGFDRLVKGFNEDD DANEELSSSGEEDLFTRKA Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
Term | Definition |
GO:0006518 | peptide metabolic process |
GO:0055114 | oxidation-reduction process |
Vocabulary: Cellular Component
Term | Definition |
GO:0016020 | membrane |
Vocabulary: Molecular Function
Term | Definition |
GO:0003824 | catalytic activity |
GO:0005507 | copper ion binding |
GO:0016715 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
GO:0004497 | monooxygenase activity |
GO:0005515 | protein binding |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category |
Term Accession |
Term Name |
biological_process |
GO:0055114 |
oxidation-reduction process |
biological_process |
GO:0006518 |
peptide metabolic process |
cellular_component |
GO:0016020 |
membrane |
molecular_function |
GO:0003824 |
catalytic activity |
molecular_function |
GO:0005507 |
copper ion binding |
molecular_function |
GO:0004497 |
monooxygenase activity |
molecular_function |
GO:0016715 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen |
molecular_function |
GO:0005515 |
protein binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
IPR000720 | Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase | PRINTS | PR00790 | PAMONOXGNASE | coord: 511..534 score: 32.14 coord: 469..488 score: 42.86 coord: 220..239 score: 59.29 coord: 268..287 score: 57.86 coord: 57..78 score: 41.56 |
IPR000323 | Copper type II, ascorbate-dependent monooxygenase, N-terminal | PFAM | PF01082 | Cu2_monooxygen | coord: 24..141 e-value: 6.8E-28 score: 97.4 |
IPR000323 | Copper type II, ascorbate-dependent monooxygenase, N-terminal | GENE3D | 2.60.120.310 | | coord: 15..163 e-value: 1.0E-37 score: 129.0 |
IPR011042 | Six-bladed beta-propeller, TolB-like | GENE3D | 2.120.10.30 | | coord: 319..503 e-value: 0.0015 score: 17.2 coord: 504..783 e-value: 1.6E-21 score: 76.2 |
IPR024548 | Copper type II ascorbate-dependent monooxygenase, C-terminal | PFAM | PF03712 | Cu2_monoox_C | coord: 164..287 e-value: 8.9E-32 score: 109.7 |
IPR014784 | Copper type II, ascorbate-dependent monooxygenase-like, C-terminal | GENE3D | 2.60.120.230 | | coord: 164..304 e-value: 5.2E-37 score: 126.3 |
IPR001258 | NHL repeat | PFAM | PF01436 | NHL | coord: 512..540 e-value: 3.8E-6 score: 26.6 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 680..710 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 800..819 |
None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 309..382 |
None | No IPR available | SUPERFAMILY | 63829 | Calcium-dependent phosphotriesterase | coord: 436..668 |
IPR013017 | NHL repeat, subgroup | PROSITE | PS51125 | NHL | coord: 503..543 score: 12.747 |
IPR013017 | NHL repeat, subgroup | PROSITE | PS51125 | NHL | coord: 544..584 score: 7.772 |
IPR013017 | NHL repeat, subgroup | PROSITE | PS51125 | NHL | coord: 449..490 score: 8.923 |
IPR008977 | PHM/PNGase F domain | SUPERFAMILY | 49742 | PHM/PNGase F | coord: 160..288 |
IPR008977 | PHM/PNGase F domain | SUPERFAMILY | 49742 | PHM/PNGase F | coord: 18..156 |
Blast
BLAST of TCONS_00004545-protein vs. Swiss-Prot (Human)
Match: AMD (Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens GN=PAM PE=1 SV=2) HSP 1 Score: 202.216 bits (513), Expect = 4.993e-54 Identity = 108/274 (39.42%), Postives = 147/274 (53.65%), Query Frame = 0
Query: 19 SSYTLFDIKMPNVSPKEDESYLCTGKKLPRTRDRYYAYKFEPNADEKTAHHMLVYACRSLSKRNRHNAYWKC-HGTPCSGGQIIYAWAKNAEGLTLPKHVGFPLGDDFDLNYIVQQIHYA--RPLQDDEYDSSGVKIRLTKYEPQFVASIYLFAS-NFQIPPNSKGYNVDMACKYRGDSIKPFAFRTHAHKHGRSISAYRVRDGVWDQIGIGSPQRPQAFYPIKKEDRLLLKSNDVLVARCTFDTMDETKTISAGSYSSDEMCNFYMMYYTMNK 288
SS DI+MP V+PK+ ++Y C ++P + + F+P A T HHML++ C S +YW C GT I+YAWA+NA LPK VGF +G + Y V Q+HY +D+ D SGV + LT+ +A +YL S + IP K N D++C Y+ + FA+R H H G+ +S YRVR+G W IG SPQ PQAFYP+ + + D+L ARC F T+ G SSDEMCN Y+MYY K
Sbjct: 54 SSDFALDIRMPGVTPKQSDTYFCMSMRIP-VDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTG---SYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHP--VDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAK 321 HSP 2 Score: 130.954 bits (328), Expect = 4.184e-31 Identity = 68/172 (39.53%), Postives = 101/172 (58.72%), Query Frame = 0
Query: 435 PIEEKTIYIVNSNDGSLFNSFGANVFYLPSSVRVDHQGHFFITDLGRHQVLKFDPLKKETLQLVLGQEGIPGEDRNHFCSPADVVVD-HKNHIYVADGLCNNRIVKFDANGKYLSEFGS---------GHLKHPQHLAISG--HHIYVATQDRHQIYVFDFDGK-FIRALSH 593
PIEE TI +++ N+ ++ S G N+FYLP + +D G++++TD+ HQV K DP KE L+LG+ PG D+NHFC P DV VD IYV+DG CN+RIV+F +GK+++++G G P LA+ + VA ++ +I F D K F+R + H
Sbjct: 553 PIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKH 724
The following BLAST results are available for this feature:
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