TCONS_00004545-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00004545-protein
Unique NameTCONS_00004545-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length819

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00004545-protein ID=TCONS_00004545-protein|Name=TCONS_00004545-protein|organism=Clytia hemisphaerica|type=polypeptide|length=819bp
MLCSILTMLYLLAGLDMISSYTLFDIKMPNVSPKEDESYLCTGKKLPRTR
DRYYAYKFEPNADEKTAHHMLVYACRSLSKRNRHNAYWKCHGTPCSGGQI
IYAWAKNAEGLTLPKHVGFPLGDDFDLNYIVQQIHYARPLQDDEYDSSGV
KIRLTKYEPQFVASIYLFASNFQIPPNSKGYNVDMACKYRGDSIKPFAFR
THAHKHGRSISAYRVRDGVWDQIGIGSPQRPQAFYPIKKEDRLLLKSNDV
LVARCTFDTMDETKTISAGSYSSDEMCNFYMMYYTMNKGEDFSVPSGCSS
TTHTLDFPKDSMLPFQSSSSNTQPQTTPVASTVKPSSKKPEQKISSTPTD
PHSKAVIITTKAPSSTHSGSSAHHSSGLPELDGSWSVEKELRSSFKGQIR
SMDVTLDYKLVVLTGVRPANNSLFDGEHFLLESKPIEEKTIYIVNSNDGS
LFNSFGANVFYLPSSVRVDHQGHFFITDLGRHQVLKFDPLKKETLQLVLG
QEGIPGEDRNHFCSPADVVVDHKNHIYVADGLCNNRIVKFDANGKYLSEF
GSGHLKHPQHLAISGHHIYVATQDRHQIYVFDFDGKFIRALSHGLSTNEI
SMVYCHAKDSKDELLYIVGKNKVVAINLQKDSSIAWQIKGTGDKVLALSR
DHRYLYIGDKDNGDIQRYLLPSSTSKNKGKNNFPWSPIDQIPSSTKPSTN
NNSSRQVDILPKTPYDDDDITVIPAVVVVAVLATPIILVFVALIIQHVRL
KHRVKRAAQKRTLDNYTKTGICTCCWSTPKYYYDSQKGFDRLVKGFNEDD
DANEELSSSGEEDLFTRKA
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_002557XLOC_002557Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00004545TCONS_00004545Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000720PHM/PAL
IPR000323Cu2_ascorb_mOase_N
IPR0110426-blade_b-propeller_TolB-like
IPR024548Cu2_monoox_C
IPR014784Cu2_ascorb_mOase-like_C
IPR001258NHL_repeat
IPR013017NHL_repeat_subgr
IPR008977PHM/PNGase_F_dom
Vocabulary: Biological Process
TermDefinition
GO:0006518peptide metabolic process
GO:0055114oxidation-reduction process
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0005507copper ion binding
GO:0016715oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
GO:0004497monooxygenase activity
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
biological_process GO:0006518 peptide metabolic process
cellular_component GO:0016020 membrane
molecular_function GO:0003824 catalytic activity
molecular_function GO:0005507 copper ion binding
molecular_function GO:0004497 monooxygenase activity
molecular_function GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000720Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyasePRINTSPR00790PAMONOXGNASEcoord: 511..534
score: 32.14
coord: 469..488
score: 42.86
coord: 220..239
score: 59.29
coord: 268..287
score: 57.86
coord: 57..78
score: 41.56
IPR000323Copper type II, ascorbate-dependent monooxygenase, N-terminalPFAMPF01082Cu2_monooxygencoord: 24..141
e-value: 6.8E-28
score: 97.4
IPR000323Copper type II, ascorbate-dependent monooxygenase, N-terminalGENE3D2.60.120.310coord: 15..163
e-value: 1.0E-37
score: 129.0
IPR011042Six-bladed beta-propeller, TolB-likeGENE3D2.120.10.30coord: 319..503
e-value: 0.0015
score: 17.2
coord: 504..783
e-value: 1.6E-21
score: 76.2
IPR024548Copper type II ascorbate-dependent monooxygenase, C-terminalPFAMPF03712Cu2_monoox_Ccoord: 164..287
e-value: 8.9E-32
score: 109.7
IPR014784Copper type II, ascorbate-dependent monooxygenase-like, C-terminalGENE3D2.60.120.230coord: 164..304
e-value: 5.2E-37
score: 126.3
IPR001258NHL repeatPFAMPF01436NHLcoord: 512..540
e-value: 3.8E-6
score: 26.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 680..710
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 800..819
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 309..382
NoneNo IPR availableSUPERFAMILY63829Calcium-dependent phosphotriesterasecoord: 436..668
IPR013017NHL repeat, subgroupPROSITEPS51125NHLcoord: 503..543
score: 12.747
IPR013017NHL repeat, subgroupPROSITEPS51125NHLcoord: 544..584
score: 7.772
IPR013017NHL repeat, subgroupPROSITEPS51125NHLcoord: 449..490
score: 8.923
IPR008977PHM/PNGase F domainSUPERFAMILY49742PHM/PNGase Fcoord: 160..288
IPR008977PHM/PNGase F domainSUPERFAMILY49742PHM/PNGase Fcoord: 18..156

Blast
BLAST of TCONS_00004545-protein vs. Swiss-Prot (Human)
Match: AMD (Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens GN=PAM PE=1 SV=2)

HSP 1 Score: 202.216 bits (513), Expect = 4.993e-54
Identity = 108/274 (39.42%), Postives = 147/274 (53.65%), Query Frame = 0
Query:   19 SSYTLFDIKMPNVSPKEDESYLCTGKKLPRTRDRYYAYKFEPNADEKTAHHMLVYACRSLSKRNRHNAYWKC-HGTPCSGGQIIYAWAKNAEGLTLPKHVGFPLGDDFDLNYIVQQIHYA--RPLQDDEYDSSGVKIRLTKYEPQFVASIYLFAS-NFQIPPNSKGYNVDMACKYRGDSIKPFAFRTHAHKHGRSISAYRVRDGVWDQIGIGSPQRPQAFYPIKKEDRLLLKSNDVLVARCTFDTMDETKTISAGSYSSDEMCNFYMMYYTMNK 288
            SS    DI+MP V+PK+ ++Y C   ++P   +  +   F+P A   T HHML++ C   S      +YW C  GT      I+YAWA+NA    LPK VGF +G +    Y V Q+HY      +D+  D SGV + LT+     +A +YL  S +  IP   K  N D++C Y+   +  FA+R H H  G+ +S YRVR+G W  IG  SPQ PQAFYP+     + +   D+L ARC F     T+    G  SSDEMCN Y+MYY   K
Sbjct:   54 SSDFALDIRMPGVTPKQSDTYFCMSMRIP-VDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTG---SYWFCDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHP--VDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAK 321          

HSP 2 Score: 130.954 bits (328), Expect = 4.184e-31
Identity = 68/172 (39.53%), Postives = 101/172 (58.72%), Query Frame = 0
Query:  435 PIEEKTIYIVNSNDGSLFNSFGANVFYLPSSVRVDHQGHFFITDLGRHQVLKFDPLKKETLQLVLGQEGIPGEDRNHFCSPADVVVD-HKNHIYVADGLCNNRIVKFDANGKYLSEFGS---------GHLKHPQHLAISG--HHIYVATQDRHQIYVFDFDGK-FIRALSH 593
            PIEE TI +++ N+ ++  S G N+FYLP  + +D  G++++TD+  HQV K DP  KE   L+LG+   PG D+NHFC P DV VD     IYV+DG CN+RIV+F  +GK+++++G          G    P  LA+      + VA ++  +I  F  D K F+R + H
Sbjct:  553 PIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSIDKDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQNHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFITQWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGRIQCFKTDTKEFVREIKH 724          
The following BLAST results are available for this feature:
BLAST of TCONS_00004545-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
AMD4.993e-5439.42Peptidyl-glycine alpha-amidating monooxygenase OS=... [more]
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