TCONS_00002864-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00002864-protein vs. Swiss-Prot (Human)
Match: HUWE1 (E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens GN=HUWE1 PE=1 SV=3)

HSP 1 Score: 1498.03 bits (3877), Expect = 0.000e+0
Identity = 926/2342 (39.54%), Postives = 1307/2342 (55.81%), Query Frame = 0

Query:    2 QHQSLIFHILKFTALLIEHSYARHLYNSVEHLITLLDCADGDIILAVLNLIYVFSKRSNYLSRLPSEKKKVLQEKLVDLAQTWGGLEAGCALEQCCSE----DVPTGAGNVYFEYYVNDTDGSSENSKGNGSTRFCIDLKNIHQISTSNVGELMESIIKAKKIPDNIQMAFYHRLRLAHAMTTYTKRLQFVQARLQALSILVYSNAAVH-VNTLVYDGLIEEIVNTLKHNEIGYKKLAEVKASCLKTLTAIIHLDRNPRLQSIIDSTGATSYHGFLPTLVRQCIQHMTRADLEPFPQQLATSLFSFLYHLASYESGCEALVASGLIEPLLKVVLWPG-QDDHITFVTRAVRVIDLITNLDMAAFQTHNGLNALVGRLQNEVKLCSGFHGPSLPSTPPIPPTGSSDDDCTMSTGLNENVTETAASGTASDVEMKEDEPTTSTSTSTPSSATIITKRNNHNQCLPQRAALLKSILNFLKKAIPDAAFVDITRSLMDENLQNALKMIISNAEYYGALLFLLATDVVTVFIFHEPSMLSSLQDSGLTWVVLRALIVKDVPATRENLASLPNTLSALCLNTRGLEAFVQCKPFERLFQILVSPEYLPAMKRRRSSDPQGDTAMHLGSAMDELMRHQPTLKTDAMKAIIKLLQRLSEMGADNKIIAFHPTDTSKSTKMTSKESQETSAAVSATPEEPLSDDEMEEEYQSLL-------IRKQDKKEHEDTEPPVDQTKSKTSERKFVPVVDYVLNVTKFLDNILSNNGTDDHCVEFVRLDGLQPLYGLLQMPNFPLEFPLMTACQSIAQVSKSIAMLSQETKVFKEGLKQLNDLMDNLDQLYANVKT-SGSVLLNELAGTDNPLEALYDSTQTPIVHAMSAVHAYINVFVYLSRGAQSDVRNMSIQNWGSELGKTVLEKLSTLYMKLVWESSALLTLCTPNIASQEDLSFAAEDLEKLTMKKIE-------KEESGE-----------------------------------VSNKKGMTQIT--------LMKWLLTSSSHLGRALAELFGLLVHQCVGMDQGSRLRRHAPNSNQPVAPSVKARSIATLLTRLLMKGLSWKCPDSIKVPRLRLTFYICSVGFSTPMLFDNLKNPYHLMLQEFQKAGGLEALFDAFDVVLQ-----EYIIGKRHEDIKSTVGIGEFLEGWLGLVNRLANTKYLFESTHTLPTTSFVPG----HEPFNSAEFMVYVHKYAFNSIMKLWDERVFKNSDNHLVAERILSIFCHILKGESQLPEKF-LQSAASKGADEKSKKNGLLTEIYRTPAPTTFGTQSTAEIVNETFVQQFVDMGFSAQHAREALLHANNNFDAATEYLLTTPAPAVPAESGSGGATGTESAAIAAATNTQEGMDVDVMSEDEMMIQAIALSLA----------TTQETTKEGASSSIASSSSTEQ---------QDTSPTPPKLTVDDLTNFQSLVVENMKGIFFGSLELLDAVPSAVHTVCDLHLAMASKNGEEWRRETLGELTEQIMRNSQVICDKIL----SSNETEQSLMKFLCESKESQQLATRLHLFLLMSQGLGNVWGNVLQTGNPFNLLIMLLKMVSNVLTKVKQIGLEVKTPELLSPLLLTFDQYEKVVLFSKRKQK-----QEKSHTWKWFDDRSGRWCNYSVSNNTSIDTAYQAGESTVRFTAGRRRYMVFFKTLVQINEDTGNRRPIMLDVLQKKTNNTKTTENNKSTDANNAETSSSSKSKTDVVMTPVERPSGKSLKRKLSREEPASSSSTSLPEPKKIEVL-EGLNNAQIESIIEYCVDLLSLQVNSNTLNAIMRLLLRFTRDYNMAQAFAHGNGVQHLLNLTEASSFPGALHLSSLLLRHIVEDTETMKNAVNRAVALASNGGVPNMFCGVGQNSVGAKELHYLLRALGPIACRNADLYNESTRKVMRISTNSWRGQLDKGLPPSITQIVKVP---QDMKTIGLNGNVKPTT--VISDFVYILLTTLAERYALERNSPTKQTEKVTSKTTATSSKKTDDGRKL--MATDSHLTASRTPQLTLVRRLTGEHIDEDEMTICTPQQATTSQATTSSKLPIDDSVKGQEDSSSTTPDSSN-----------TDEAKK-----KPLLSASAILKLLAELSKSYAAVARIIVDFVYDTSNLSQSARSYVNDGSTALCFIFDRLLPYSTRDPTQATTENTKDNKPSVISTLARQLLSVLGSYWHNVDIQNVFITELKSALSRTLQYPESRSKHLHLQALFNLITSMIESAAPI-SFSSQPPLQN-----TTFVKLLIKRGLISDLAKITHSLDLSSHDLVPTVNLMLKPLEKLSNLAN 2211
            Q + L+  +L FTALLIE+S++RHLY+S+EHL TLL  +D  ++LAVLNL+YVFSKRSNY++RL S+K+  L  +L  LA++WGG E G  L +CC +      P  A  ++FE+Y +         +   +T   I ++ + +IS S   E+MES+ K   IP + QM  +  +RLAH  + + KRLQ VQARL A+SILVYSNA     N+++Y+GLIEE+V+ L   +I  K+L E+KA+ L+TLT+I+HL+R P+L SIID TG  SYHGFLP LVR CIQ M    ++P+P Q AT+LFSFLYHLASY++G EALV+ G++E LLKV+ + G + D ITFVTRAVRV+DLITNLDMAAFQ+H+GL+  + RL++EV LC                      +C            T   G   + +M                        +  QC+PQRAALLKS+LNFLKKAI D AF D  R +MD +L  +LK IISNAEYYG  LFLLAT+VVTVF+F EPS+LSSLQD+GLT V+L AL++KDVPATRE L SLPN  SALCLN RGL++FVQC+PFERLF++L+SP+YLPAM+RRRSSDP GDTA +LGSA+DELMRHQPTLKTDA  AIIKLL+ +  +G D K I   P+             Q+     +A P  P S+   EE             ++  +  +  +TEP  +Q    T ER  +P++DY+LNV KF+++ILSNN TDDHC EFV   GL PL  +L +PN P++FP   ACQ++A V KSI  LS E KV +EGL QL+ ++ +L+ L+  +++  GSVLL ELA   N  +A   +  TP++HA++A HAYI +FV+  R  QS++R++S+  WGS+LG +VL KLS LY  LVWES+ LL+LCTPN +      F   D++KL  K  +       K   GE                                    S+ KG ++IT         +K LL++SS LGRALAELFGLLV  CVG     R   HA ++    AP+  ARS A+ LT+LL KGLSW+ P     PR RLTF+ICSVGF++PMLFD  K PYHLMLQ+F  +GG  ALF+ F+  L          G  H D+    G GEFL+ WL LV ++ N   + ES H+LP    +PG       F++  F+V   K AF  I  LW+ +  K     + AE +L+I CHIL+GE  + E+   +   S+G ++  ++ G              G++   + VN+  +QQ +DMGF+ +HA EALL+  +  + ATEYLLT P P +      GG     S                 MSE++ M++AIA+SL           + +E           +    E+         QD  P    L  D+L  F   ++        G   LLD +P  V+ VCDL +    +NG ++R   L ++  Q+   + V+    L    S  +T    +  +    ++  LATR+ L  L+ + L      V+++    N+LI LL++V   L   K+   EV+TP+ ++P+LL  D YEK  + SKR+ +     Q  S+ W+WFDDRSGRWC+YS SNN++ID+A+++GE++VRFTAGRRRY V F T+VQ+NE+TGNRRP+ML +L+    N    +N+K+++    E +     + D+     +R   K     L+ E   +   TSL E K  E+L +GL    +  +I  CV +L + V+ +TL+A +RL LR TRD+  A  FA     + +LNLT++S F G   L +LLLRHI+ED  T+++ + + V  A+  G  +   GV   S+G++E++Y+LR LGP ACRN D++ E     +RI+  + RG             +K P   Q +KT  L  +  P     I + +Y +L  LA  +A E    +     V ++           G+ L  M  D +            R LT +  D D  +      +  SQ   +     + S  G     ++TP+ S            ++E K+     KPL+  S IL+LLAEL +SY  +A +I ++ Y    + QS    + +  + L F+ D LLP+         T+N +D        LAR  L+ L +     D Q   + E+K+AL R L   ES  KH  LQA+  +I++++ES     SF S    +         ++L +K+GL++DLA++ HSLDLSS ++  TVN  LKPLE LS + N
Sbjct:   88 QLKMLLLAVLNFTALLIEYSFSRHLYSSIEHLTTLLASSDMQVVLAVLNLLYVFSKRSNYITRLGSDKRTPLLTRLQHLAESWGGKENGFGLAECCRDLHMMKYPPSATTLHFEFYADPGAEVKIEKRTTSNTLHYIHIEQLDKISESP-SEIMESLTKMYSIPKDKQMLLFTHIRLAHGFSNHRKRLQAVQARLHAISILVYSNALQESANSILYNGLIEELVDVL---QITDKQLMEIKAASLRTLTSIVHLERTPKLSSIIDCTGTASYHGFLPVLVRNCIQAMIDPSMDPYPHQFATALFSFLYHLASYDAGGEALVSCGMMEALLKVIKFLGDEQDQITFVTRAVRVVDLITNLDMAAFQSHSGLSIFIYRLEHEVDLCR--------------------KECPFVIKPKIQRPNTTQEGEEMETDM------------------------DGVQCIPQRAALLKSMLNFLKKAIQDPAFSDGIRHVMDGSLPTSLKHIISNAEYYGPSLFLLATEVVTVFVFQEPSLLSSLQDNGLTDVMLHALLIKDVPATREVLGSLPNVFSALCLNARGLQSFVQCQPFERLFKVLLSPDYLPAMRRRRSSDPLGDTASNLGSAVDELMRHQPTLKTDATTAIIKLLEEICNLGRDPKYICQKPS------------IQKADGTATAPP--PRSNHAAEEASSEDEEEEEVQAMQSFNSTQQNETEP--NQQVVGTEERIPIPLMDYILNVMKFVESILSNNTTDDHCQEFVNQKGLLPLVTILGLPNLPIDFPTSAACQAVAGVCKSILTLSHEPKVLQEGLLQLDSILSSLEPLHRPIESPGGSVLLRELACAGNVADATLSAQATPLLHALTAAHAYIMMFVHTCRVGQSEIRSISVNQWGSQLGLSVLSKLSQLYCSLVWESTVLLSLCTPN-SLPSGCEFGQADMQKLVPKDEKAGTTQGGKRSDGEQDGAAGSMDASTQGLLEGIGLDGDTLAPMETDEPTASDSKGKSKITPAMAARIKQIKPLLSASSRLGRALAELFGLLVKLCVGSPVRQRRSHHAASTT--TAPTPAARSTASALTKLLTKGLSWQPPPYTPTPRFRLTFFICSVGFTSPMLFDERKYPYHLMLQKFLCSGGHNALFETFNWALSMGGKVPVSEGLEHSDLPD--GTGEFLDAWLMLVEKMVNPTTVLESPHSLPAK--LPGGVQNFPQFSALRFLVVTQKAAFTCIKNLWNRKPLKVYGGRM-AESMLAILCHILRGEPVIRERLSKEKEGSRGEEDTGQEEG--------------GSRREPQ-VNQQQLQQLMDMGFTREHAMEALLN-TSTMEQATEYLLTHPPPIM------GGVVRDLS-----------------MSEEDQMMRAIAMSLGQDIPMDQRAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADP----LEQDELHTFTDTMLP-------GCFHLLDELPDTVYRVCDLIMTAIKRNGADYRDMILKQVVNQVWEAADVLIKAALPLTTSDTKTVSEWISQMATLPQASNLATRILLLTLLFEELKLPCAWVVESSGILNVLIKLLEVVQPCLQAAKEQK-EVQTPKWITPVLLLIDFYEKTAISSKRRAQMTKYLQSNSNNWRWFDDRSGRWCSYSASNNSTIDSAWKSGETSVRFTAGRRRYTVQFTTMVQVNEETGNRRPVMLTLLRVPRLN----KNSKNSNGQELEKTLEESKEMDI-----KRKENKGNDTPLALESTNTEKETSLEETKIGEILIQGLTEDMVTVLIRACVSMLGVPVDPDTLHATLRLCLRLTRDHKYAMMFAELKSTRMILNLTQSSGFNGFTPLVTLLLRHIIEDPCTLRHTMEKVVRSAATSGAGSTTSGVVSGSLGSREINYILRVLGPAACRNPDIFTEVANCCIRIALPAPRGSGTASDDEFENLRIKGPNAVQLVKTTPLKPSPLPVIPDTIKEVIYDMLNALAAYHAPEEADKSDPKPGVMTQEV---------GQLLQDMGDDVY---------QQYRSLTRQSSDFDTQS----GFSINSQVFAADGASTETSASGTSQGEASTPEESRDGKKDKEGDRASEEGKQKGKGSKPLMPTSTILRLLAELVRSYVGIATLIANYSY---TVGQS--ELIKEDCSVLAFVLDHLLPH---------TQNAEDKD---TPALARLFLASLAAAGSGTDAQVALVNEVKAALGRALAMAESTEKHARLQAVMCIISTIMESCPSTSSFYSSATAKTQHNGMNNIIRLFLKKGLVNDLARVPHSLDLSSPNMANTVNAALKPLETLSRIVN 2258          

HSP 2 Score: 260.381 bits (664), Expect = 8.722e-69
Identity = 219/555 (39.46%), Postives = 289/555 (52.07%), Query Frame = 0

Query: 3097 PGPSSSQTTADQIRRELESLGMPEGVDPSFLAALPDNIREEVLREQFGIRLQSTRATTGSSSSGAGPSLSLLQQGAAAVTSDPP-QEVSPEFLAALPEEFQREVLEQQRMEQARFTAAQQ-TPDVPVDAAEFVRNLPPPLRRQVLADMDDTVLAVLPAELSTEAQGLRRELEQRR---------ANQTRTDFSQILRHTGMAR--SGGASFQSIARLFPRGGPM-----SSWKVTDGHPNSSGQKKLGRQLLDPESLTCLLVLLFLNDSTLNATRLHRILRNLSYHNPTKQWIILALISILRRTSSLNQENMVALNKQFAAPTSTPTTSSTNKSPKSSKKVV-----KSGDFCEELPPNSNVSQSSVHEHWLSRTLNLAFGGCVNIFQI-------HKESESSRKPWDYFVTVHQQACLDVSKQTLEALSFLAKNFPSSFTPQLEKNKEEESQGESGVKEPDAEASSQ------SEFWDVLVRLNSSRSGQKGKAPSKCLKEFPKVENST---SFVGSPLVKILSMLSHPVIKQSTLLTDKLLRLLAVISMSLPE 3612
            P PS+S    D     L  + +PEGVDPSFLAALPD+IR EVL+ Q GIR   TR    ++SS            A AV  +P   EVSPEFLAALP   Q EVL QQR EQ R   AQ  + D P+D   F++ LP  LRR VL DM+D+VLAV+P +++ EAQ LRRE E R+          + + +  S ILR        SG    Q       RGG       SS     G    +  +  GR LLD E+L+CLLVLLF+++  LN +RLHR+LRNL YH  T+ W+I +L+SIL+R+S            +    T   TTS       S          +  D   ++      S+SS    WLS +++ A G   NIFQI       H E  +S       V +H QA   V +  L+ L  LAK FPS FT Q  K    ES  E G K     +S        ++FWD+LV+L++    +KGK   K +      E  T   S   SPL ++++MLSHPVI++S+LLT+KLLRLL++IS++LPE
Sbjct: 2947 PLPSTSSEEED----PLAGISLPEGVDPSFLAALPDDIRREVLQNQLGIR-PPTRTAPSTNSS------------APAVVGNPGVTEVSPEFLAALPPAIQEEVLAQQRAEQQRRELAQNASSDTPMDPVTFIQTLPSDLRRSVLEDMEDSVLAVMPPDIAAEAQALRREQEARQRQLMHERLFGHSSTSALSAILRSPAFTSRLSGNRGVQYTRLAVQRGGTFQMGGSSSHNRPSGSNVDTLLRLRGRLLLDHEALSCLLVLLFVDEPKLNTSRLHRVLRNLCYHAQTRHWVIRSLLSILQRSS----------ESELCIETPKLTTSEEKGKKSSKSCGSSSHENRPLDLLHKME-----SKSSNQLSWLSVSMDAALGCRTNIFQIQRSGGRKHTEKHAS---GGSTVHIHPQAAPVVCRHVLDTLIQLAKVFPSHFTQQRTKETNCESDRERGNKACSPCSSQSSSSGICTDFWDLLVKLDNMNVSRKGKNSVKSVPVSAGGEGETSPYSLEASPLGQLMNMLSHPVIRRSSLLTEKLLRLLSLISIALPE 3466          

HSP 3 Score: 156.377 bits (394), Expect = 3.114e-37
Identity = 122/354 (34.46%), Postives = 184/354 (51.98%), Query Frame = 0

Query: 3789 QLRLAVNVLTAGTCSDEGLEDATTLLLHLSRTEPVTRDSILELLLEGAQETANCLQLEIKSLLNELKERNLKAGKQPASENKSSKQNVPVIVNPSLSRSQPWRGRGARSNTQSRRRGGLTMGGQ-----TQRRNVPKPVIYDLHLPAMATLTAKRSNQSLFLRILKVILQLRDAAKKIAKKPQGSSNPTSRPRGFRLIERLHHGGSSLREVVAALEADMEAMYDMIDRFGGGNAGAGAEGGAGSRNRTGADSNAGNNAGNNASNDQAGNNEDSAAGSSNQEDKPAEEEEPE--------MPKFPALSSQLQLDALWDVLGDALAELAETTDTNAVLVLQPAVESFFLVHGSEKE 4129
            QL+L+V VLT+ +CS+EGLEDA  +LL LSR +  TRD++L+LLL GA+     L  +I +LL EL+E NL+  ++   E  S            L   QP   +  +   QSR      M        +Q+R +      +L LP+M+ LT+K S Q  FLR+L+VI+QLRD  ++  KK + +          RL        SS++  V  LEA+ +A+  M+              G  +R +  A ++  + +  +   +++  + D  + S+      A +  P+         P+ P LS QL LD LWD+LG+ L EL E+ D +AVLVLQPAVE+FFLVH +E+E
Sbjct: 3580 QLQLSVEVLTSHSCSEEGLEDAANVLLQLSRGDSGTRDTVLKLLLNGARHLGYTLCKQIGTLLAELREYNLEQQRRAQCETLSPD---------GLPEEQPQTTK-LKGKMQSR----FDMAENVVIVASQKRPLGG---RELQLPSMSMLTSKTSTQKFFLRVLQVIIQLRDDTRRANKKAKQTG---------RLGSSGLGSASSIQAAVRQLEAEADAIIQMVRE------------GQRARRQQQAATSESSQSEASVRREESPMDVDQPSPSAQDTQSIASDGTPQGEKEKEERPPELPLLSEQLSLDELWDMLGECLKELEESHDQHAVLVLQPAVEAFFLVHATERE 3895          

HSP 4 Score: 85.8853 bits (211), Expect = 5.973e-16
Identity = 109/386 (28.24%), Postives = 158/386 (40.93%), Query Frame = 0

Query: 2547 SHPLMVRQNEQPNRTNERSSR--------GRAGRVDRALTRQHGNTIHIHG----------------GNSGFARILIGDELRPTNSRSVDNTLIPGDDVFF----------DIFGDGYETPS--GLLNSVPSALSRWTVESRLLDGSSVHDCVNTLKPDIIKHLE--------------KLQMVEIQEKIA----EEKAKKEESKRAAAEKAKSSQSTTTS----------TTASSNTTSTTTTSNTLTTITSSAAV-TLSVEPS-NATAAHTSTPSLESSTRSPRLVSSRLTTQDFTAPSNNITSADNQESGDQEANQMDVSPSSSSTVADIPPPIAETPASAESTIAYDTPFNPMPEFIPNAPQREEP---TSNAGAQATPAAG 2863
            +HPLMVR  +  + T    S         GR+ R  R LT   G+TIH+H                 G S  A IL      P  SR     L+  DDV            D F D     S  G L+S+P+AL+RWT E ++LD  S+HDCV+ +K  I+ HLE              + Q+ E + KI     E+K  +++S +  A K+  S     S          TT SS   +T+ +  TL T+ SS    TL   P+         +P+ E  + +  L+         T P           SG+ E  QM++SP  + T+  + P  AE  + A + ++     +PM      +   EE    TS AG+   P AG
Sbjct: 2515 THPLMVRHADHSSLTLGSGSSTTRLTQGIGRSQRTLRQLTANTGHTIHVHYPGNRQPNPPLILQRLLGPSAAADILQLSSSLPLQSRGRARLLVGNDDVHIIARSDDELLDDFFHDQSTATSQAGTLSSIPTALTRWTEECKVLDAESMHDCVSVVKVSIVNHLEFLRDEELEERREKRRKQLAEEETKITDKGKEDKENRDQSAQCTASKSNDSTEQNLSDGTPMPDSYPTTPSSTDAATSESKETLGTLQSSQQQPTLPTPPALGEVPQELQSPAGEGGSSTQLLMPVEPEELGPTRP-----------SGEAETTQMELSP--APTITSLSPERAED-SDALTAVSSQLEGSPMDTSSLASCTLEEAVGDTSAAGSSEQPRAG 2886