Sequence
The following sequences are available for this feature:
polypeptide sequence
>TCONS_00000946-protein ID=TCONS_00000946-protein|Name=TCONS_00000946-protein|organism=Clytia hemisphaerica|type=polypeptide|length=281bp MYRTFRIPQLAFLGAGTLAETLTKGFIAAGALQINQIWASAPSDTHVMKL GCKTTTDNVKLVKENKLVALSVKPQVLPKVLREISPHITPDHLLLSFAAG MKIRNMQYLLPPKTRIARLMTNTPTQFREGVSSFALGPHCREADRKLIQD LMSTVGYCTEVKENLLDVVTGFAGGGPAYAYCFIEAIADAAVLGGMTREE AMKMAAKSVLGAARMVEETGDHPGKLKDDVCSAGGSTIRGIHALEKGRMR SAVIDAVNAATERSSELGKILNEQGSSNKIF Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following
gene feature:
This polypeptide derives from the following
transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
Term Definition
GO:0004735 pyrroline-5-carboxylate reductase activity
Vocabulary: Biological Process
Term Definition
GO:0006561 proline biosynthetic process
GO:0055114 oxidation-reduction process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category
Term Accession
Term Name
biological_process
GO:0055114
oxidation-reduction process
biological_process
GO:0006561
proline biosynthetic process
molecular_function
GO:0004735
pyrroline-5-carboxylate reductase activity
InterPro
Analysis Name:
InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
20 40 60 80 100 120 140 160 180 200 220 240 260 280 Expect = 3.9E-13 / Score = 49.7 Expect = 9.5E-41 / Score = 138.0 Expect = 6.0E-21 / Score = 74.9 Expect = 2.3E-76 / Score = 254.8 Expect = 3.9E-77 / Score = 256.8 Score = Score = 23.889 Expect = 5.2E-35 / Score = 119.7 Score = Score = Sequence PF03807 G3DSA:1.10.3730.10 G3DSA:3.40.50.720 TIGR00112 PIRSF000193 PS00521 MF_01925 PF14748 SSF48179 SSF51735
IPR Term IPR Description Source Source Term Source Description Alignment
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal PFAM PF03807 F420_oxidored coord: 10..100 e-value: 3.9E-13 score: 49.7
None No IPR available GENE3D 1.10.3730.10 coord: 162..272 e-value: 9.5E-41 score: 138.0
None No IPR available GENE3D 3.40.50.720 coord: 6..161 e-value: 6.0E-21 score: 74.9
IPR000304 Pyrroline-5-carboxylate reductase TIGRFAM TIGR00112 TIGR00112 coord: 10..267 e-value: 2.3E-76 score: 254.8
IPR000304 Pyrroline-5-carboxylate reductase PIRSF PIRSF000193 P5CR coord: 8..270 e-value: 3.9E-77 score: 256.8
IPR000304 Pyrroline-5-carboxylate reductase PROSITE PS00521 P5CR coord: 223..245
IPR000304 Pyrroline-5-carboxylate reductase HAMAP MF_01925 P5C_reductase coord: 8..267 score: 23.889
IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain PFAM PF14748 P5CR_dimer coord: 163..267 e-value: 5.2E-35 score: 119.7
IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like SUPERFAMILY 48179 6-phosphogluconate dehydrogenase C-terminal domain-like coord: 162..269
IPR016040 NAD(P)-binding domain SUPERFAMILY 51735 NAD(P)-binding Rossmann-fold domains coord: 10..161
Blast
BLAST of TCONS_00000946-protein vs. Swiss-Prot (Human)
Match:
P5CR3 (Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens GN=PYCR3 PE=1 SV=3)
HSP 1 Score: 224.557 bits (571), Expect = 8.420e-73
Identity = 111/264 (42.05%), Postives = 168/264 (63.64%), Query Frame = 0
Query: 9 QLAFLGAGTLAETLTKGFIAAGALQINQIWASAPSD---THVMKLGCKTTTDNVKLVKENKLVALSVKPQVLPKVLREISPHITPDHLLLSFAAGMKIRNMQYLLPPKTRIARLMTNTPTQFREGVSSFALGPHCREADRKLIQDLMSTVGYCTEVKENLLDVVTGFAGGGPAYAYCFIEAIADAAVLGGMTREEAMKMAAKSVLGAARMVEETGDHPGKLKDDVCSAGGSTIRGIHALEKGRMRSAVIDAVNAATERSSELGK 269
++ F+GAG +A + +G I AG ++ I ASAP+D H LGC+TT N ++++ LV + KP VLP VL E++P +T +H+L+S AAG+ + ++ LLPP TR+ R++ N P +EG A G H ++ KL+Q L+ G C EV E +D+ TG +G G A+ F EA+A+ AV GM A ++AA+++LG A+M+ G HP +L+ DVC+ GG+TI G+HALE+G +R+A + AV AAT R+ EL +
Sbjct: 10 RVGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNLCHFQALGCRTTHSNQEVLQSCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLPPNTRVLRVLPNLPCVVQEGAIVMARGRHVGSSETKLLQHLLEACGRCEEVPEAYVDIHTGLSGSGVAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGLHALEQGGLRAATMSAVEAATCRAKELSR 273
The following BLAST results are available for this feature:
BLAST of TCONS_00000946-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (
Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens) )
Total hits: 1
M Y R T F R I P Q L A F L G A G T L A E T L T K G F I A A G A L Q I N Q I W A S A P S D T H V M K L G C K T T T D N V K L V K E N K L V A L S V K P Q V L P K V L R E I S P H I T P D H L L L S F A A G M K I R N M Q Y L L P P K T R I A R L M T N T P T Q F R E G V S S F A L G P H C R E A D R K L I Q D L M S T V G Y C T E V K E N L L D V V T G F A G G G P A Y A Y C F I E A I A D A A V L G G M T R E E A M K M A A K S V L G A A R M V E E T G D H P G K L K D D V C S A G G S T I R G I H A L E K G R M R S A V I D A V N A A T E R S S E L G K I L N E Q G S S N K I F 20 40 60 80 100 120 140 160 180 200 220 240 260 280 Expect = 8.42e-73 / Id = 42.05 Sequence P5CR3
Match Name E-value Identity Description
P5CR3 8.420e-73 42.05 Pyrroline-5-carboxylate reductase 3 OS=Homo sapien... [more]
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