TCONS_00000488-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00000488-protein
Unique Name	TCONS_00000488-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	516

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00000488-protein ID=TCONS_00000488-protein|Name=TCONS_00000488-protein|organism=Clytia hemisphaerica|type=polypeptide|length=516bp
MDLPDTHNLTSIIGQIDTWDEEGHLTQLLLSILSIGVTISPECWLKFPIM
CIGCNWHQITASLRQTEYHEVVTTICTLCNLINGFIPENIEFERKDWFVL
QKLRRSAQYEPNLRPNFPKISETVNVTIQLVTIENLDLSHSSFKLDFLLR
QEWNDHRLRHHHPAVLDGSNLRMGVWVPDSYFVQAKRGVFSRVAHDGQTI
KVKSNGDVSHGARITLEVSCPIDLRNFPMDIQHCNLDMESYAYSTEEITY
NWSPHEVIMKNIKETSKSLSQYTLEPIKTGKGSSEYVLGNWSKLQIEFKF
VRNSIIFIPAMYFPCAMVVFITWITFLMDSAQYPARTYLCVTSLLTIVTL
QTAMNASLPKVSYVKAIDKYIVGCILFVAGAFLEYAVVLLINIKKNSVLM
ENSSLVSNNHDNIFNNFSYALQPRSEKSKSSLKKKLRRRKITFLRSRLTS
PKEFHDDQTSSVNDQQIVLTKFGAIFHFYLSDAWPKKLDVISRVFFPSLF
LTFNLFYWITHVDDQY

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_000306	XLOC_000306	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00000488	TCONS_00000488	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006028	GABAA/Glycine_rcpt
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 220..234 score: 52.82 coord: 144..160 score: 35.19 coord: 174..185 score: 33.18
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	PRINTS	PR00253	GABAARECEPTR	coord: 491..511 score: 49.18 coord: 333..354 score: 40.87 coord: 307..327 score: 31.14 coord: 367..388 score: 44.13
None	No IPR available	GENE3D	1.20.58.390		coord: 306..514 e-value: 2.5E-32 score: 110.9
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 311..431 e-value: 2.9E-20 score: 73.3
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 307..512
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 100..300 e-value: 2.8E-34 score: 118.4
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 98..303 e-value: 1.1E-39 score: 135.7
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 105..303
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 220..234

Blast

[Close]

BLAST of TCONS_00000488-protein vs. Swiss-Prot (Human)
Match: GLRA2 (Glycine receptor subunit alpha-2 OS=Homo sapiens GN=GLRA2 PE=1 SV=1)

HSP 1 Score: 201.83 bits (512), Expect = 4.512e-59
Identity = 128/429 (29.84%), Postives = 216/429 (50.35%), Query Frame = 0

Query:   98 FVLQKLRRSAQYEPNLRPNF--PKISETVNVTIQLVTIENLDLSHSSFKLDFLLRQEWNDHRLRHHH---------PAVLDGSNLRMGVWVPDSYFVQAKRGVFSRVAHDGQTIKVKSNGDVSHGARITLEVSCPIDLRNFPMDIQHCNLDMESYAYSTEEITYNW---SPHEVIMKNIKETSKSLSQYTL-EPIKTGKGSSEYVLGNWSKLQIEFKFVRNSIIFIPAMYFPCAMVVFITWITFLMDSAQYPARTYLCVTSLLTIVTLQTAMNASLPKVSYVKAIDKYIVGCILFVAGAFLEYAVVLLINIKKNSVLMENSSLVSNNHDNIFNNFSYALQPRSEKSKSSLKKKLRRRKITFLRSRLTSPKEFHDDQTSSVNDQQIVLTKFGAIFHFYLSDAWPKKLDVISRVFFPSLFLTFNLFYWITH 511
            F+ + + R++ Y+  +RPNF  P ++ T N+ I   +  ++  +   ++++  LRQ+WND RL +           P++LD       +W PD +F   K   F  V  D + +++  NG V +  R+TL +SCP+DL+NFPMD+Q C + +ES+ Y+  ++ + W    P +V          +L Q+ L E  + G  +  Y  G ++ ++++F   R    ++  MY P  ++V ++W++F ++    PAR  L +T++LT+ T  +   ASLPKVSYVKAID ++  C+LFV  A LEYA V  ++ +    L         N +          + R   S   +   L+ +  T +++   +P      Q     D         AI   ++  A  K++D ISR  FP  FL FN+FYWIT+
Sbjct:   47 FLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFIN--SFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPDDSLDLDPSMLDS------IWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQV------AEGLTLPQFILKEEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEE-----DVTRESRFNFSGYGMGHCLQVKDGTAVKATPANPLP----QPPKDGD---------AIKKKFVDRA--KRIDTISRAAFPLAFLIFNIFYWITY 441

The following BLAST results are available for this feature:

BLAST of TCONS_00000488-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00000488-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GLRA2	4.512e-59	29.84	Glycine receptor subunit alpha-2 OS=Homo sapiens G...	[more]

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TCONS_00000488-protein (polypeptide) - C. hemisphaerica