TCONS_00000044-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00000044-protein
Unique NameTCONS_00000044-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length751

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00000044-protein ID=TCONS_00000044-protein|Name=TCONS_00000044-protein|organism=Clytia hemisphaerica|type=polypeptide|length=751bp
RKNLRLKKRYNFHMMHSLWIIIAASISMCSASECSLTDFELYQQTCMNNT
LYSTFNETKMLEVIENCFPWISHNFPQCWQAVHSNITTSKCQQTCQYFQN
HCPMLALFDSTKCFSRCVVGAENRQQKYENLLSLNCSQNTVAKTCAGNFV
SSSHSSEWAIQWNYQNQKQDNEIVNTTSGCALSCDNQIQVFRSGQLQVDG
PIICFSLLGIIASSFTVLSFLIDWKSQNRYPALILFITSICFMMCFLGWI
IQFFGVGRKISCDPTNLRRNKEPRHGDSFWCILSFILIYFSGLSTSCWFV
ILNYSWYISFRTMGSIKTLIQSKIKYFHFFAWGISGSFTLMALLLQAVSA
HPITNICFIHLSHNQQHLHDGLVAFPFTVCLVVGEFLLLKCVIQLKKLRN
DCSIFLVPKAVKNLTKTFYRMIIYGLGVLVAFTLLVFIMYYEFNMREEWE
KKHSKYIRCRLETVSLPTSLSKECIPPDKSRLLCLHCYILLLLLMSLLTS
SWTWTFGTLKIWKKAWKRHLETDKAKERLQFQRAWYRRINSKKIQPFLPP
INPQNPLEENKIKFMQPDKRLSLPDNLFVSTHQGDKKNRRHSDDIRSVVE
LFSIRRNTMCSLNSVISNEVSLKPVHSIQSFGHLSIAHNIPSNRGAPTNL
TVIQVYQNPTNTDELQRQFLNKPQTTNLTSDEIRHIRDRLYTPLTTAHKD
SIIADCLPYNRTDLEPDLISSAVELRQSVRNHEFYNSIELIESLSIHSTK
I
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_000028XLOC_000028Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00000044TCONS_00000044Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000539Frizzled
IPR017981GPCR_2-like
Vocabulary: Biological Process
TermDefinition
GO:0007166cell surface receptor signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Molecular Function
TermDefinition
GO:0004888transmembrane signaling receptor activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0007166 cell surface receptor signaling pathway
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0016020 membrane
molecular_function GO:0004888 transmembrane signaling receptor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000539Frizzled proteinPRINTSPR00489FRIZZLEDcoord: 327..350
score: 32.33
coord: 230..252
score: 26.43
coord: 201..223
score: 36.17
coord: 374..396
score: 29.57
coord: 484..504
score: 16.57
coord: 283..307
score: 37.44
IPR000539Frizzled proteinSMARTSM01330Frizzled_2coord: 189..522
e-value: 6.5E-36
score: 135.3
IPR000539Frizzled proteinPFAMPF01534Frizzledcoord: 202..518
e-value: 3.6E-58
score: 197.1
NoneNo IPR availableGENE3D1.20.1070.10coord: 198..543
e-value: 1.4E-8
score: 33.5
IPR017981GPCR, family 2-likePROSITEPS50261G_PROTEIN_RECEP_F2_4coord: 208..400
score: 18.753

Blast
BLAST of TCONS_00000044-protein vs. Swiss-Prot (Human)
Match: SMO (Smoothened homolog OS=Homo sapiens GN=SMO PE=1 SV=1)

HSP 1 Score: 194.512 bits (493), Expect = 3.031e-52
Identity = 118/464 (25.43%), Postives = 216/464 (46.55%), Query Frame = 0
Query:   73 HNFPQCWQAVHSNITTSKCQQTCQYFQNHCPMLALFDSTKCFSRCVVGAENRQQKYENLLSLNCSQNTVAKTCAGNFVSSSHSSEWAIQWNYQNQKQDNEIVNTTSGCALSCDNQIQVFRSGQLQ-VDGPIICFSLLGIIASSFTVLSFLIDWKSQNRYPALILFITSICFMMCFLGWIIQFF-GVGRKISCDPTNLRRNKEPRHGDSFWCILSFILIYFSGLSTSCWFVILNYSWYISFRTMGSIKTLIQSKIKYFHFFAWGISGSFTLMALLLQAVSAHPITNICFIHLSHNQQHLHDGLVAFPFTVCLVVGEFLLLKCVIQLKKLRNDCSIFLVPKAVKNLTKTFYRMIIYGLGVLVAFTLLVF-IMYYEFNMREEWEKKHSKYIRCRLE-TVSLPTSLS-KECIPPDKSRLLCLHCYILLLLLMSLLTSSWTWTFGTLKIWKKAWKR-HLETDKAKERLQ 530
             N P+CW AV   +  +     C+  +   P   L  +T+    C +    R++ + + L   C+ +   + C     +   +S    +                 GC + C N +  F   + Q +   I  F  +  + + FT+ +F+ DW++ NRYPA+ILF  + CF +  +GW+ QF  G  R+I C      R  EP   ++  C++ F+++Y++ ++   WFV+L Y+W+ SF+ +G+    +  K  YFH   W +    T+  L +  V    ++ ICF+   +       G V  P  + L+VG + L++ V+ L  ++++    L  KA   + +T  R+ I+G  +   F L+ F   +Y+F  + EWE+    Y+ C+   T+ LPT     +C   ++  LL     +  +    +  S+W WT  TL IW++ W R   ++D   +R++
Sbjct:  113 RNAPRCW-AVIQPLLCAVYMPKCENDRVELPSRTLCQATR--GPCAI--VERERGWPDFL--RCTPDRFPEGCTNEVQNIKFNSSGQCEVPLVRTDNPKSWYEDVEGCGIQCQNPL--FTEAEHQDMHSYIAAFGAVTGLCTLFTLATFVADWRNSNRYPAVILFYVNACFFVGSIGWLAQFMDGARREIVCRADGTMRLGEPTSNETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSFKALGTTYQPLSGKTSYFHLLTWSLPFVLTVAILAVAQVDGDSVSGICFV--GYKNYRYRAGFVLAPIGLVLIVGGYFLIRGVMTLFSIKSNHPGLLSEKAASKINETMLRLGIFGF-LAFGFVLITFSCHFYDFFNQAEWERSFRDYVLCQANVTIGLPTKQPIPDCEIKNRPSLLVEKINLFAMFGTGIAMSTWVWTKATLLIWRRTWCRLTGQSDDEPKRIK 564          
The following BLAST results are available for this feature:
BLAST of TCONS_00000044-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
SMO3.031e-5225.43Smoothened homolog OS=Homo sapiens GN=SMO PE=1 SV=... [more]
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