Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
transcript:BL00081_cuf6transcript:BL00081_cuf6mRNA
transcript:BL00082_cuf1transcript:BL00082_cuf1mRNA
transcript:BL00083_cuf19transcript:BL00083_cuf19mRNA
transcript:BL00084_evm0transcript:BL00084_evm0mRNA
transcript:BL00085_cuf21transcript:BL00085_cuf21mRNA
transcript:BL00086_cuf1transcript:BL00086_cuf1mRNA
transcript:BL00087_evm0transcript:BL00087_evm0mRNA
transcript:BL00088_evm1transcript:BL00088_evm1mRNA
transcript:BL00089_cuf0transcript:BL00089_cuf0mRNA
transcript:BL00091_evm0transcript:BL00091_evm0mRNA
transcript:BL00092_evm6transcript:BL00092_evm6mRNA
transcript:BL00093_evm0transcript:BL00093_evm0mRNA
transcript:BL00094_evm0transcript:BL00094_evm0mRNA
transcript:BL00095_evm0transcript:BL00095_evm0mRNA
transcript:BL00096_evm0transcript:BL00096_evm0mRNA
transcript:BL00097_cuf1transcript:BL00097_cuf1mRNA
transcript:BL00098_evm3transcript:BL00098_evm3mRNA
transcript:BL00099_evm16transcript:BL00099_evm16mRNA
transcript:BL00100_evm0transcript:BL00100_evm0mRNA
transcript:BL00101_evm1transcript:BL00101_evm1mRNA
transcript:BL00102_cuf0transcript:BL00102_cuf0mRNA
transcript:BL00103_evm0transcript:BL00103_evm0mRNA
transcript:BL00104_evm0transcript:BL00104_evm0mRNA
transcript:BL00105_evm0transcript:BL00105_evm0mRNA
transcript:BL00106_evm0transcript:BL00106_evm0mRNA

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