Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
BlTCONS00000076BlTCONS00000076mRNA
BlTCONS00000077BlTCONS00000077mRNA
BlTCONS00000078BlTCONS00000078mRNA
BlTCONS00000079BlTCONS00000079mRNA
BlTCONS00000080BlTCONS00000080mRNA
BlTCONS00000081BlTCONS00000081mRNA
BlTCONS00000082BlTCONS00000082mRNA
BlTCONS00000083BlTCONS00000083mRNA
BlTCONS00000084BlTCONS00000084mRNA
BlTCONS00000085BlTCONS00000085mRNA
BlTCONS00000086BlTCONS00000086mRNA
BlTCONS00000087BlTCONS00000087transcript
BlTCONS00000088BlTCONS00000088transcript
BlTCONS00000089BlTCONS00000089transcript
BlTCONS00000090BlTCONS00000090mRNA
BlTCONS00000091BlTCONS00000091mRNA
BlTCONS00000092BlTCONS00000092mRNA
BlTCONS00000093BlTCONS00000093mRNA
BlTCONS00000094BlTCONS00000094mRNA
BlTCONS00000095BlTCONS00000095mRNA
BlTCONS00000096BlTCONS00000096mRNA
BlTCONS00000097BlTCONS00000097mRNA
BlTCONS00000098BlTCONS00000098mRNA
BlTCONS00000099BlTCONS00000099mRNA
BlTCONS00000100BlTCONS00000100mRNA

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