Branchiostoma lanceolatum

Overview
Full NameBranchiostoma lanceolatum
GenusBranchiostoma
Specieslanceolatum
Common NameAmphioxus
AbbreviationB. lanceolatum
Interest

The phylogenetic position of amphioxus, together with its relatively simple and evolutionarily conserved morphology and genome structure, has led to its use as a model for studies of vertebrate evolution. In particular, recent development of technical approaches, as well as access to the complete amphioxus genome sequence, for the Mediterranean amphioxus, Branchiostoma lanceolatum has provided the community with tools with which to study the invertebrate-chordate to vertebrate transition (Bertrand & Escriva, 2011).

Location:

Mediterranean Sea and North-East Atlantic

Attractive features
  • Controlled spawning induction
  • Transparent embryos
  • Micromanipulation techniques available allowing functional approaches in classical embryology and developmental biology
Contributions

Studies with different amphioxus species have helped answer questions about the evolution of the chordate genome, and particularly the evolution of the Hox cluster structure and cis-regulatory elements, the evolution of the control of axial patterning in chordates, and the appearance of vertebrate-specific structures such as the head.

Tools
  • Assembled and annotated genome sequence (550 MB) and many transcriptome resources soon publically available
  • Epigenomic resources including Chip-seq, ATAC-seq, Methylome, CAGE-seq, and 4C for a panel of transcription factors are available for several developmental stages
Drawbacks

Due to a short spawning period (May-July), in vivo experiments are restricted to a short period only. Their life cycle is also relatively long, about 2 years to reach adulthood, and no knockdown techniques are available (no morpholinos, RNAi or siRNA).

Selected references
  • Bertrand S. & Escriva H. (2011) Evolutionary crossroads in developmental biology: amphioxus. Development 138: 4819-30
Transcript Browser
The following browser provides a quick view for new visitors. Use the searching mechanism to find specific features.
NameUnique NameType
BlTCONS00000051BlTCONS00000051transcript
BlTCONS00000052BlTCONS00000052transcript
BlTCONS00000053BlTCONS00000053mRNA
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BlTCONS00000057BlTCONS00000057mRNA
BlTCONS00000058BlTCONS00000058mRNA
BlTCONS00000059BlTCONS00000059mRNA
BlTCONS00000060BlTCONS00000060mRNA
BlTCONS00000061BlTCONS00000061transcript
BlTCONS00000062BlTCONS00000062transcript
BlTCONS00000063BlTCONS00000063transcript
BlTCONS00000064BlTCONS00000064transcript
BlTCONS00000065BlTCONS00000065transcript
BlTCONS00000066BlTCONS00000066transcript
BlTCONS00000067BlTCONS00000067transcript
BlTCONS00000068BlTCONS00000068transcript
BlTCONS00000069BlTCONS00000069transcript
BlTCONS00000070BlTCONS00000070mRNA
BlTCONS00000071BlTCONS00000071mRNA
BlTCONS00000072BlTCONS00000072mRNA
BlTCONS00000073BlTCONS00000073mRNA
BlTCONS00000074BlTCONS00000074mRNA
BlTCONS00000075BlTCONS00000075mRNA

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