TCONS_00055963-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00055963-protein vs. Swiss-Prot (Human)
Match: SACS (Sacsin OS=Homo sapiens GN=SACS PE=1 SV=2)

HSP 1 Score: 514.612 bits (1324), Expect = 8.229e-147
Identity = 663/2690 (24.65%), Postives = 1121/2690 (41.67%), Query Frame = 0

Query:    6 CIPTKPNGR-LRRTNQLIQEGSDVSILYDVTDERFPDLKDND------VIKYLQTHGMEAGGLSWTKILDRAQTV------EQSANKERGSALLRIISKKLERKDFPATQSDVEACNQLKGTKFLPVMKKPKKCLFNKWHGSTAK---VSSPKEIYPHSFSNTLSCSNYICSE---------KMDDSVVKLFQIKVTPRQEDLATQLNEFLPKFKTTDFKYRDALKEITILY-SEAEVKEETRLF-----LSQAKFIMADNGQLYSADTMFLQVDHIITGKLHSIHGSYKDMKESERVQELFFNVGVKPKATATDYATALKGLWEEYNNNRLTK--FHI------DEIYHLLPVLADFEEKHLFIDDLY----LPDQQNILRKTSELCYNDVTWLP-NDPDVHYSNSEISHQHAIQLKIKSRRSDYILRGKHIDDTPWIDDSQVTT--ESFGQYDNLTARIKRLIENYSDPFDILKETIQNADDAESNEIEFILDKRSHGTEKVISEKWEHLQGPGLLIVNDGKFTTEDLQGIQKLGVGSHKNDPLKTGKYGVGFNTVYSLTDCPILLTKVDGTEDRMCMFDPHRKYAEGATDKRPGCSFPDART-FLDPYDDVKSAFLFNEEDKETKTILRLPFRMGDTAKDSEISTTSVSIKTIEKTMKGFLEHADEFLLFLNNIKTIKI-RIVNGEGEKDELFSVHSKLYDTLPSTVDSFKVSAKGFADRFGDIYSMIDSEMQLHRKHCIRHLKDDKVQHATH-------------WDVFEQVGFSSFDDLPDSVKDTLESQTHHLVPKGGIAKLSSKDDCVECDREKCSKNTSYTKLKSLFCTLPINLETGISGIINGNFFLDSDNRRALY---NGEDKNKEWNQSILNHCVLPCFISHL-EFVKKHIEGKFNLQKVERKPDPK-SQQNEQPDDIFLEKCLRRISINNFLSLFPSTEESTDKYFKIFTKAFYMRITDKGNRLLPVHRPGDVK----------FW-------SPREFL-------LFEGKDSSCNLL-------NVMKMANLKVDVLPDPIIKDFSESGNKH------DYSLTTATPTVVRELL----NRENRLVFFKDGMEHSKSSLKTVENINTLLSFCLKKENDKRHSNPKNSKMDSDTPPKADEKAPSIDLTGLPLCLLQDRTLKSFNSK-PAFLTKYSTLFNEEKSRFMHKSSFSTLSQEHIEHSCFKEFDLHQFKDMLQNSTFNDLLKDSKIGDKDCKVNEFKAWIKNCWELIESCFHEEKRKQKEEEKKRKREQKDESEEGKDKTKEVKVDYLENQLDIIKDVPLLLVKKGTKESLLPIENRKKILGPDHNNNKIYDFITKACGGFEVV---TCYKQTKQDQDTYCHQIYSRTMLGRMFGKADKFNDVVAALKYALSSSPGQ-ELPVELTIDFLSRLSLMD-GIENKIPRDGKASLCSLPLFQHHDGKLVEAS--GNVCILPKLVPKSALSVIESKFTITVLENIPTLEKLYTGLGFETKGDEQFYMKYVIPSLTKFT-DAQIQEYLY------PYRDVVKVRTHVLDRLKGIPFVSTNESSCTRKDCSKLFHPDNELFKLMEPAGNF-PN------KGMYSMSNFGDFERDRWLDFFLSLGMCQCIESGDHFLKYARMLEDEDNEEK-VKKVSQMLCKILLENLLSKDENVKKWSLDSNFLCKLKDIRFIAPHTGNKKFENMFPSK---NSSTKRIAFNGSVTSNSF------ELLWTSKHVLPTYAVNYGNKSMSLDVMSELGISNKDTVQMEFVKQNLTTILTSQDYLEATGSSSC--FSVKAEHRDFYNKALTEVYEFCLKHPENIE-SLIDVSFILVNQSKMLEQPRRCI--QQVIGTINPFLNEVHIAHGKYFSVFQSLGCSENAKFSHYVDVLSQIKQVEENQGKGFLDEKLVFRATRAVTYMSRVLFDDVSTKWKQD--------LYLPTFKFSDLKIRMVISNECLILDDASLEERLKLFDQPILRSSSLEGISVEKD--VNDKLLKYLPSSTKPKTFRASVEEVLCE----TCIPAQIDKKHGARIWKQRMKNPAFINGFKRLLSHEE----IKEEQNYEKILKSVQ----IAVMENLQTELRFEGVK-IEGSKIAKNVFTHLTDEQLVIYFDKEYSSEQV-----VSASISNAISELFGDILKTRQTITCFTKLLEMKPDQIPGFLDSQKIVNLG---DHSTFRRAGKPPPLGKPIPQEHHGILNFDVSFIIEVGDYVAYDENDEGED--------YVYAKIVSMNKDGSVKIQLVNDEDVDEED--GXTYDENDEGEDYVYAKIVSMNKDGSVKIQLVNDEDVDEEDGEGSRDVPRSTLYKFENKYTKGTEAEVENTQEDSSQSQEIAQFGDDGENGNARKRQRTEKPKTREETRSFEEIRDDIKKIIHDLKSKDEDEQKRVLRRLYLQWHPDKHP-NKDLATEVFKFLMNEKKRLDSD--FSEHFERWNEQASHNRSSR-QSYERDFDDFFRHFGQQRSGSSRSRNSGSSRSRNDYTGNGFHYD-NVPPRFTRENPQPAEARRWFKQAQHDFNQASE--MRACPEWICYVSHQVAEKALKAAIFS------KDYQGALYNEHNLCNLIREFQHADQELRNDLQELQTLVVDEDEPRYPRWS--MKIPHEKFNQQKADRALVLAQRIV 2495
            CIP    G  L   ++LI     V+ L+D+ D RFP     D      +IK +Q  GM    + W  +L+RA +V      +  A   R S LL +I +KL+ +D  A   D  A  + +  +FLP + KP     + W G++ K   + +  ++Y     + +     I +E          +  +V +   +   P  + +  QL E           Y++ +      Y  EA ++ E         L    FI+ +N  + S    F  ++      L+ +   YK+       +ELF  VGV+   T  D+A  L+ + +E    ++T+  F +      + I+ L+      E+K  F +  Y    LPD   +L     LCYND  W+   D  V Y +++I  + A++L    +R   + R        +  +   TT    FGQ + LT+RIK ++  Y    ++LKE +QNADDA++ EI F+ D R H  +++  +KW  LQGP L + N+  FT +D++GIQ LG G+ + +P KTG+YG+GFN+VY +TDCP  ++      D +C+FDPH +YA GAT   PG  F D    F   + DV   +L      +  T+ R P R  + AK SEIS+   S + ++  +        E L+FLN+++ I I  I    G  + L+SV  K+        D  ++  K F        S+IDS   + +K   R LKD  VQ  T+             W +  + GFSS + +  SV    ++Q   L P+GG+A       C+           +Y K    FC LP++LETG+   +NG+F LDS  RR L+   NG     +WN S++   + P ++  L +  K++  G           DP  S     P  +       + ++  FLS FP              KA Y  I +   RLLPV R  ++            W         R F        L   K++  N+        NV ++ +L +++  + ++ +  E+ N +      D  ++  TP  +R  L    + +      K      +++LK   ++  L+ +C K                       D +   I++ GLPL +  D  L++F++K P FLT Y  L    K  FM+ + +   S   +     K FD+  F D+L +    +    S    KD   +E  +W+KN W  I         K+ +EE K   +   ++ +        K     NQ         L+V +G  + LLP+      + P+  ++K++  + KA G  ++     C K +       CH               +    ++ AL Y + +S  + E  VE   DF + L   +  + + + +D    L SLP ++   G+ V     G   +L K +P + +       +   LE    L++LY  +G     D + Y+K+++P +   + DA+++  +Y         ++ +++  + ++L+ +  +  ++++   K     +     +F++M P   F PN      + +    N   F    W++F  ++G+ + I S    L++A+ +    N E   K+  Q    ILL ++  +  ++    L  NFL +L  I F+ P     +F    P     N +   I FNG+  +  F      +LLWTS  +LP  A     K       S+LG   +    +  +  NL   L   D +     + C   ++  E      K L  +YEF           L  V+F++V     L +P   +   +      P+L ++ +  G +  +F+ LG  +      YV+VLS+I   + ++GK  LD   +    R V+ + R L +D S K + D        LYLP+      +   ++ +  L+ DDA   +     +  +     L    + KD   + KL+   P   +P+   + +EE L E     C    +    G    +  + +  FI G  R++ HE     +  E+   ++ K+++    ++  E LQT LR +G   I  S+     F       +++ + +   S+ +     ++ ++ +A   L  D       + C         + I  +   +K+ +LG   D S   +   P P G PIP E H  L  D   +   G+YV Y  + EG D        Y YA IV          Q V  ED D     G  Y  +    +Y   KIVS     S+ +   +      E+   SRD   ST        T G  +              I       E+     + ++ K   + +  S  EI  ++  ++       E E+K+++RRLYL+WHPDK+P N D+A EVFK L NE  RL+      ++ +R + +     +SR QS +  F  F+  + Q+ +     R   +        G  +     VPP F +    P EARRW +QA+ +F+ A     +   EW+C+  +   + AL AA ++      KD +        L   I E+    + L ND+  L+   VD  + RYP      +IP+++F  + A R +     I+
Sbjct: 2097 CIPCSLEGHPLVLPSRLIHPEGRVAKLFDIKDGRFPYGSTQDYLNPIILIKLVQL-GMAKDDILWDDMLERAVSVAEINKSDHVAACLRSSILLSLIDEKLKIRDPRA--KDFAA--KYQTIRFLPFLTKPAGFSLD-WKGNSFKPETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKEVAKSVDDGITLYQENITNACYKYLHEALMQNEITKMSIIDKLKPFSFILVENAYVDSEKVSF-HLNFEAAPYLYQLPNKYKN-----NFRELFETVGVRQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIR-----EKKQEFCEKNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVKYCHADIPREVAVKLGAVPKRHKALER--------YASNVCFTTLGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFISG----NDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSVKGKI-------TDGDRLKRKQFHA------SVIDS---VTKK---RQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAA------CI---------THNYKKPHRAFCFLPLSLETGLPFHVNGHFALDS-ARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGS----------DPTLSVLQNTPIHVV------KDTLKKFLSFFPVNRLDLQPDLYCLVKALYNCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFN-LVYNCDETANLYHCLIDADIPVSYVTPADIRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFK-----------------------DAEENEIEVEGLPLLITLDSVLQTFDAKRPKFLTTYHELIPSRKDLFMN-TLYLKYSNILLNCKVAKVFDISSFADLLSSVLPREYKTKSCTKWKDNFASE--SWLKNAWHFISESV---SVKEDQEETKPTFDIVVDTLKDWALLPGTKFTVSANQ---------LVVPEG--DVLLPLSLMHIAVFPNAQSDKVFHALMKA-GCIQLALNKICSKDSAFVPLLSCHT-----------ANIESPTSILKALHYMVQTSTFRAEKLVE--NDFEALLMYFNCNLNHLMSQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKIHLKELYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKEQLFEKLESLLII--HDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPNDFFKKLEQLIKPKNHVTF-MTSWVEFLRNIGL-KYILSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERMDL----LSGNFLKELSLIPFLCPERAPAEFIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQE---GSDLGPQEQLEQVLNMLNVNLDPPL---DKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRI--FKNSEGKQ-LDPNEMRTVKRVVSGLFRSLQND-SVKVRSDLENVRDLALYLPS------QDGRLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGR--LQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGC---------NDI--YRIGEKLDSLGVKYDSSEPSKLELPMP-GTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIV----------QEVEREDADNSSFLGKIYQIDIGYSEY---KIVS-----SLDLYKFS----RPEESSQSRDSAPSTPTSPTEFLTPGLRS--------------IPPLFSGRESHKTSSKHQSPK---KLKVNSLPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQNKEKCPPSAGQTYSQRFFVPPTF-KSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPT-----ALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACII 4568          

HSP 2 Score: 139.043 bits (349), Expect = 2.360e-32
Identity = 123/441 (27.89%), Postives = 202/441 (45.80%), Query Frame = 0

Query:  410 FGQYDN-LTARIKRLIENYSDPFDILKETIQNADDAESNEIEFILDKRSHGTEKVISEKWEHLQGPGLLIVNDGKFTTEDLQGIQKLGVGSHKNDPLKTGKYGVGFNTVYSLTDCPILLTKVDGTEDRMCMFDPHRKYAEGATDKRPGCSFPDARTFLDPYDDVKSAFL-FNEEDKET-------KTILRLPFRMGDTAKDSEISTTSVSIKTIEKTMKGFLEHADEFLLFLNNIKTIKIRIVNGEGEKDELFSVHSKLYDTL----PSTVDSFKVSAKGFADRFGDIYSMIDSEMQLHRKHCIRHLKDDKVQHA--THWDVFEQVGFSSFDDLPDSVKDTLESQTHHLVPKGGIA-KLSSKDDCVECDREKCSKNTSYTKLKSLFCTLPINLE--TGISGIINGNFFLDSDNRRALYNGE-----DKNKEWNQSILNHCV 827
            FGQ    L   +K ++  Y +   ILKE IQNA+DA + E++F+ D+  +GTE + S+     QGP L + N+  FT ED  GIQ++     K+DPLK G++G+GFN+VY +TD P + +      D++ M DPH+    G  +     +  D    +    D  + F+      KET        T  R P R+    + S++S+   + + + +  + F   AD  LLFL +++ + + +   +G +  +F V S     L    P+++     +   +  +         + +     H    L+++  + A  T W V   VG        DS+ D L+      VP  GIA  LSS+DD      E     + ++     F  LP   E  TG+   I+G FF  +DNRR++   E     D    WN+ ++ + V
Sbjct:   89 FGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSG-----DQIGMLDPHQTLF-GPHESGQCWNLKDDSKEISELSDQFAPFVGIFGSTKETFINGNFPGTFFRFPLRL----QPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTEKLVFRVTSSESKALKHERPNSIKILGTAISNYCKK------TPSNNITCVTYHVNIVLEEESTKDAQKTSWLVCNSVGGRGISSKLDSLADELK-----FVPIIGIAMPLSSRDD------EAKGATSDFSGKAFCFLPLPPGEESSTGLPVHISG-FFGLTDNRRSIKWRELDQWRDPAALWNEFLVMNVV 501          

HSP 3 Score: 111.694 bits (278), Expect = 4.945e-24
Identity = 80/272 (29.41%), Postives = 133/272 (48.90%), Query Frame = 0

Query:  397 TPWIDDSQVTTESFGQYDNLTARIKRLIENYSDPFDILKETIQNADDAESNEIEFILDKRSHG--TEKVISEKWEHLQGPGLLIVNDGKFTTEDLQGIQKLGVGSHKNDPLKTGKYGVGFNTVYSLTDCPILLTKVDGTEDRMCMFDPHRKY-AEGATDK-RPGC------------SFPDA-RTFLDPYD-----DVKSAFLFNEEDKETKTILRLPFRMGDTAKDSEISTTSVSIKTIEKTMKGFLEHADEFLLFLNNIKTIKIRIVNGE 646
            T  I+   +  E  GQ + LT RIK ++E Y    DI KE +QNADDA + E  F++D R +    E ++        GP L   N+ +F+  D   I +LG    + +  K GK+G+GFN+VY +TD PI++++     + M MFDP+  + ++   DK  PG              FP+  + F+D +       V++ + +N       T+ RL FR    AK SE+S+T  +   I   +  F       ++F  ++K++ ++ +  E
Sbjct: 1441 TRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSR-----EFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLTVEAPYSYN------GTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVKSMYLKYLKIE 1701