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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00003748-protein ID=TCONS_00003748-protein|Name=TCONS_00003748-protein|organism=Clytia hemisphaerica|type=polypeptide|length=882bp
KKRKISLVFICLFIANQCTQQGKTSQRGKKKISLIHSTGTGLQIRKRSNN
SSDYVLTCINAPRKTIREKRISIQWYKDTKEWGIERYFKATGRLYKHNNN
QRKLILIGIREADSGTYHCVPFHHPSLVNSVDIPPKAAPQIHSYLPRIRI
KKINEFTKFSCVTSSKYARSWEWFINGKKVDQDDRQNFKVVKFNYLRIQK
IPYEYDGLNKVECVVTNDFGTSTMNYTLIVEGQYTKPKFVKVRERPIFDL
GLEGHTMDCRAFGKRPVNITWYHDGVDIRRKYRTGYQYFFLDDDHQRLTI
NNAHYTDSGIYKCVLKNKYGSISRQSTFRWPGPHITFTHLDGRAPGIKLI
SATIGEELVMETTFSDFDLTTNFRLELFKLVSTTHQKASELAWNASSIID
LEDNHLPSDVHGTPNFVDDQGVVMENMNRFVKYMVGSINNRGTSKKVKMV
MKNITKHSFGDYMLMVSTQYSYDVFNFTIVQDSPAGEDNSIEIAVGVTIP
ILIVVAIGSYVYFKSRHRYLKPRRRSDIMPIVRQDSDASFESVAVRRIRQ
SFYDEHIDSNWEIEPSKLTKHESIGAGNFGDVFRGQLEDLNGNLTTVAIK
TVKGSASDGDINNFFKEIEIMKRVDGRDHPNVLAFYGVCTRNLFAVLEYC
SNGNLRDYLRSKRPSEENKDVGLDRTEMLTIYSQICDGLCFLASKNIIHR
DIAARNVLVTSDFTMKIADFGLARSLNKDYYQMRSTGEMPILWMAIESIT
KGLFTVKSDVWSFAILMWEVETLGGRPYTGISVQLLSSFLTSGRRLHKPH
WTPEKIYTVMLMCWEEEPSRRPSFEDLQMIFDSIANTTSTTSSSSYTALV
HRQFHSDILEIIPNHLAVEGLRQSKSNHYNTL Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004672 | protein kinase activity |
| GO:0004713 | protein tyrosine kinase activity |
| GO:0005524 | ATP binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
| molecular_function |
GO:0004713 |
protein tyrosine kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PRINTS | PR00109 | TYRKINASE | coord: 758..780
score: 59.45
coord: 802..824
score: 42.03
coord: 647..660
score: 47.35
coord: 691..709
score: 58.98
coord: 739..749
score: 48.98 |
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PFAM | PF07714 | Pkinase_Tyr | coord: 569..829
e-value: 1.5E-82
score: 276.7 |
| IPR003598 | Immunoglobulin subtype 2 | SMART | SM00408 | igc2_5 | coord: 49..126
e-value: 1.3
score: 6.0
coord: 252..320
e-value: 4.9E-8
score: 42.7 |
| IPR020635 | Tyrosine-protein kinase, catalytic domain | SMART | SM00219 | tyrkin_6 | coord: 568..831
e-value: 6.3E-109
score: 377.9 |
| IPR003599 | Immunoglobulin subtype | SMART | SM00409 | IG_3c | coord: 246..331
e-value: 0.059
score: 22.5
coord: 43..134
e-value: 52.0
score: 5.2
coord: 146..231
e-value: 110.0
score: 2.4 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 130..236
e-value: 3.1E-7
score: 29.7 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 237..329
e-value: 1.2E-13
score: 50.5 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 45..125
e-value: 1.5E-5
score: 24.2 |
| IPR013098 | Immunoglobulin I-set | PFAM | PF07679 | I-set | coord: 255..324
e-value: 3.1E-10
score: 39.9 |
| None | No IPR available | PIRSF | PIRSF000615 | TyrPK_CSF1-R | coord: 663..878
e-value: 4.0E-58
score: 195.3
coord: 556..666
e-value: 3.2E-10
score: 36.7
coord: 77..485
e-value: 0.015
score: 11.3 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 654..877
e-value: 2.1E-46
score: 157.7 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 545..653
e-value: 1.0E-21
score: 76.5 |
| None | No IPR available | CDD | cd00096 | Ig | coord: 256..324
e-value: 1.07312E-9
score: 55.1879 |
| None | No IPR available | CDD | cd00192 | PTKc | coord: 574..832
e-value: 3.71374E-114
score: 351.071 |
| None | No IPR available | CDD | cd00096 | Ig | coord: 55..133
e-value: 7.41675E-4
score: 37.8539 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 574..600 |
| IPR008266 | Tyrosine-protein kinase, active site | PROSITE | PS00109 | PROTEIN_KINASE_TYR | coord: 697..709 |
| IPR007110 | Immunoglobulin-like domain | PROSITE | PS50835 | IG_LIKE | coord: 139..231
score: 6.778 |
| IPR007110 | Immunoglobulin-like domain | PROSITE | PS50835 | IG_LIKE | coord: 56..119
score: 7.831 |
| IPR007110 | Immunoglobulin-like domain | PROSITE | PS50835 | IG_LIKE | coord: 237..329
score: 11.896 |
| IPR007110 | Immunoglobulin-like domain | SUPERFAMILY | 48726 | Immunoglobulin | coord: 254..328 |
| IPR007110 | Immunoglobulin-like domain | SUPERFAMILY | 48726 | Immunoglobulin | coord: 52..82
coord: 161..231
coord: 112..119 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 568..831
score: 37.206 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 552..832 |
Blast
BLAST of TCONS_00003748-protein vs. Swiss-Prot (Human)
Match: FGFR1 (Fibroblast growth factor receptor 1 OS=Homo sapiens GN=FGFR1 PE=1 SV=3) HSP 1 Score: 236.884 bits (603), Expect = 3.948e-66 Identity = 146/446 (32.74%), Postives = 237/446 (53.14%), Query Frame = 0
Query: 443 TSKKVKMV-MKNITKHSFGDYMLMVS-----TQYSYDVFNFTIVQDSPAGEDNSI--EIAVGVTIPILIVVAIGSYVYFKSR--------HRYLKPRRRSDIMPIVRQ-----DSDASFES--VAVRRIRQSF-----------YDEHIDSNWEIEPSKLTKHESIGAGNFGDVFRGQL----EDLNGNLTTVAIKTVKGSASDGDINNFFKEIEIMKRVDGRDHPNVLAFYGVCTRN--LFAVLEYCSNGNLRDYLRSKRPS--------EENKDVGLDRTEMLTIYSQICDGLCFLASKNIIHRDIAARNVLVTSDFTMKIADFGLARSLNK-DYYQMRSTGEMPILWMAIESITKGLFTVKSDVWSFAILMWEVETLGGRPYTGISVQLLSSFLTSGRRLHKPHWTPEKIYTVMLMCWEEEPSRRPSFEDLQMIFDSIANTTS 839
T K+++++ ++N++ G+Y + + +S + +++ PA + + EI + T LI +GS + +K + H + + + +P+ RQ DS AS S + VR R S Y+ D WE+ +L + +G G FG V + +D +T VA+K +K A++ D+++ E+E+MK + H N++ G CT++ L+ ++EY S GNLR+YL+++RP N + L ++++ Q+ G+ +LASK IHRD+AARNVLVT D MKIADFGLAR ++ DYY+ + G +P+ WMA E++ ++T +SDVWSF +L+WE+ TLGG PY G+ V+ L L G R+ KP ++Y +M CW PS+RP+F+ L D I TS
Sbjct: 319 TDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG--KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS 762
The following BLAST results are available for this feature:
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