TCONS_00072941-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00072941-protein
Unique NameTCONS_00072941-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length565

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00072941-protein ID=TCONS_00072941-protein|Name=TCONS_00072941-protein|organism=Clytia hemisphaerica|type=polypeptide|length=565bp
SHVYLPAIFVEMNRLEWYHYVNYTLFTLLMSTKYILVVADGDHPTVTSSN
NGLNTSQILLNTSMAVNSTNETNSYSSNNTFHEGHKKMKKKFPPEGYEGR
ESGVHDGPQRINLTVWVESIVNIDVSAMEYVVHGYVIQEWVDARLNGSLD
HPILLSGEEGRAIWLPDLFCLSCRSSTLNSPTNGNVLIKVYPNGSIYYSQ
LAKLHGSCFMKLHYFPFDNQICPLNLSSYGYSNEYLVYEWKSTPVVEKMQ
LEQFIVNENVLPHNEIKSYPAGDFNILSFELFFTRQIGFYVLQVFIPSIV
LVSLSWMTFYMEPADVGDRLSIGVTLILTMIFLLGYINQSLPKVSYIKAV
DWYVIASLFMIVASVIESVLVYWLLHRKQKKQKEQNSFERFDRYLDKKFN
MNNSFLPLPLLQGGAQAAGISMPNLPSLGNNQKPFYPRMTSLQELNEKPK
PNGINPKKPIFAKLEEDEDIDESDKNGETNFCSEKDPLTKPVIRNRVNSK
FNYHRDSLMEQREKKKSDESEESESKQYNPNLDKISKLDIFARTVFPLFY
VIFTLAYFIYFFGTK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_045252XLOC_045252Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00072941TCONS_00072941Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006028GABAA/Glycine_rcpt
IPR006201Neur_channel
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006028Gamma-aminobutyric acid A receptor/Glycine receptor alphaPRINTSPR00253GABAARECEPTRcoord: 541..561
score: 32.57
coord: 350..371
score: 22.81
coord: 290..310
score: 40.54
coord: 316..337
score: 34.31
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 281..293
score: 30.53
coord: 131..147
score: 28.64
coord: 162..173
score: 36.2
coord: 208..222
score: 49.8
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 55..294
e-value: 6.5E-37
score: 126.6
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 99..285
e-value: 3.5E-29
score: 101.7
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 105..286
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 295..558
e-value: 1.9E-25
score: 90.2
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 288..403
coord: 487..562
NoneNo IPR availableGENE3D1.20.58.390coord: 295..564
e-value: 1.2E-44
score: 151.4
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 467..486
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 504..527
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 208..222

Blast
BLAST of TCONS_00072941-protein vs. Swiss-Prot (Human)
Match: GLRA3 (Glycine receptor subunit alpha-3 OS=Homo sapiens GN=GLRA3 PE=1 SV=2)

HSP 1 Score: 168.703 bits (426), Expect = 3.215e-46
Identity = 107/354 (30.23%), Postives = 184/354 (51.98%), Query Frame = 0
Query:   59 LLNTSMAVNSTNETNSYSSNNTFHEGHKKMKKKFPPEGYEGRESGVHDGPQRINLT--VWVESIVNIDVSAMEYVVHGYVIQEWVDARLNGSL--DHPILLSGEEGRAIWLPDLFCLSCRSSTLNSPTNGNVLIKVYPNGSIYYSQLAKLHGSCFMKLHYFPFDNQICPLNLSSYGYSNEYLVYEWKS---TPVVEKMQLEQFIVNENVLPHNEIKSYPAGDFNILSFELFFTRQIGFYVLQVFIPSIVLVSLSWMTFYMEPADVGDRLSIGVTLILTMIFLLGYINQSLPKVSYIKAVDWYVIASLFMIVASVIESVLVYWL---------LHRKQKKQKEQNSFERFDRYLD 396
            LL + +A   T+   S S+  +  +   K+  +    GY+ R      GP  +N+T  +++ S  +I  + M+Y V+ ++ Q+W D RL  S   D  + L      +IW PDLF  + + +  +  T  N L++++ NG++ YS    L  SC M L  FP D Q C + L S+GY+   L++EW+      V E + L QF++ E        K Y  G F  +       RQ+G+Y++Q++IPS+++V LSW++F++       R+++G+T +LTM         SLPKVSY+KA+D ++   L  + ++++E   V ++           RK+K + E  + E+F R+ D
Sbjct:   21 LLLSLVATKETDSARSRSAPMSPSDFLDKLMGR--TSGYDARIRPNFKGPP-VNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSD 371          
The following BLAST results are available for this feature:
BLAST of TCONS_00072941-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GLRA33.215e-4630.23Glycine receptor subunit alpha-3 OS=Homo sapiens G... [more]
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