TCONS_00070842-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00070842-protein
Unique NameTCONS_00070842-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length510

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00070842-protein ID=TCONS_00070842-protein|Name=TCONS_00070842-protein|organism=Clytia hemisphaerica|type=polypeptide|length=510bp
MALEIKKVLISDKVDSSCQTVLEENSIEVDYKPGLSKDELKAIIKDYDGL
IVRSATKVTQDVYDCAERLKIIGRAGTGVDNIDQISASAKGVLVMNTPGG
NTLSAAEHTCAMISALARHIGQGYASMLEGKWERSKFMGCELGGKTLAII
GLGRIGREVASRMQSYGMKTVGYDPLVSPEEAATFGVEYLQLKNIWPIAD
FVTVHVPLIKPTRGMINASVFEVCKPSMKVINVARGGIIDEKDLLNALNA
GKCGGAALDVFETEPPKEGSVSMELVKHPKTLCTPHLGASTTEAQLRVAK
EIAEQFVDAVNGKPMVGLVNAPALSQLANPLYAPWVELAQKLGSLASNLS
DSANLTLHLDGDELKPATRLLNTALCFGLAKAKGLDCNMISAVSLLKEKN
IVVVNSPTPKDLAYSALSVSTSENSWLVTGFLSRGRPCIGTLQNTELANP
VVLESGLVYAVSDSSEKELLLTSAEMGVSSVSLSRNGNRVVFVASVAEKP
ANELFKFIQF
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_044065XLOC_044065Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00070842TCONS_00070842Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006139D-isomer_2_OHA_DH_cat_dom
IPR006140D-isomer_DH_NAD-bd
IPR029009ASB_dom
IPR029753D-isomer_DH_CS
IPR029752D-isomer_DH_CS1
IPR016040NAD(P)-bd_dom
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0008152metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0051287NAD binding
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008152 metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0051287 NAD binding
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableGENE3D3.40.50.720coord: 5..110
e-value: 1.0E-31
score: 108.9
NoneNo IPR availableGENE3D3.40.50.720coord: 111..290
e-value: 8.4E-51
score: 171.8
NoneNo IPR availableCDDcd12173PGDH_4coord: 7..313
e-value: 1.74288E-165
score: 472.671
NoneNo IPR availableSUPERFAMILY52283Formate/glycerate dehydrogenase catalytic domain-likecoord: 6..139
IPR006139D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainPFAMPF003892-Hacid_dhcoord: 8..320
e-value: 7.6E-37
score: 125.9
IPR006140D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domainPFAMPF028262-Hacid_dh_Ccoord: 111..288
e-value: 1.1E-55
score: 187.6
IPR029009Allosteric substrate binding domainGENE3D3.30.1330.90coord: 324..449
e-value: 1.9E-9
score: 37.1
IPR029009Allosteric substrate binding domainSUPERFAMILY143548Serine metabolism enzymes domaincoord: 331..444
IPR029753D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved sitePROSITEPS00670D_2_HYDROXYACID_DH_2coord: 195..217
IPR029752D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1PROSITEPS00065D_2_HYDROXYACID_DH_1coord: 147..174
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 101..288

Blast
[Close]
BLAST of TCONS_00070842-protein vs. Swiss-Prot (Human)
Match: SERA (D-3-phosphoglycerate dehydrogenase OS=Homo sapiens GN=PHGDH PE=1 SV=4)

HSP 1 Score: 433.335 bits (1113), Expect = 1.128e-147
Identity = 219/409 (53.55%), Postives = 289/409 (70.66%), Query Frame = 0 
Query:    5 IKKVLISDKVDSSCQTVLEENSIEVDYKPGLSKDELKAIIKDYDGLIVRSATKVTQDVYDCAERLKIIGRAGTGVDNIDQISASAKGVLVMNTPGGNTLSAAEHTCAMISALARHIGQGYASMLEGKWERSKFMGCELGGKTLAIIGLGRIGREVASRMQSYGMKTVGYDPLVSPEEAATFGVEYLQLKNIWPIADFVTVHVPLIKPTRGMINASVFEVCKPSMKVINVARGGIIDEKDLLNALNAGKCGGAALDVFETEPPKEGSVSMELVKHPKTLCTPHLGASTTEAQLRVAKEIAEQFVDAVNGKPMVGLVNAPALSQLANPLYAPWVELAQKLGSLASNLSDSANLTLHL--DGDELKPATRLLNTALCFGLAK--AKGLDCNMISAVSLLKEKNIVVVNSPTP 409
            ++KVLISD +D  C+ +L++  ++V  K  LSK+EL A ++D +GLIVRSATKVT DV + AE+L+++GRAGTGVDN+D  +A+ KG+LVMNTP GN+LSAAE TC MI  LAR I Q  ASM +GKWER KFMG EL GKTL I+GLGRIGREVA+RMQS+GMKT+GYDP++SPE +A+FGV+ L L+ IWP+ DF+TVH PL+  T G++N + F  CK  ++V+N ARGGI+DE  LL AL +G+C GAALDVF  EPP++ +    LV H   +  PHLGAST EAQ R  +EIA QFVD V GK + G+VNA AL+   +P   PW+ LA+ LG+L    + S   T+ +   G  LK A   L+ A+  GL K  +K  D N+++A  L+KE  + V  S +P
Sbjct:    6 LRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQATASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDNTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRA----LVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMRAWAGSPKGTIQVITQGTSLKNAGNCLSPAVIVGLLKEASKQADVNLVNAKLLVKEAGLNVTTSHSP 410
The following BLAST results are available for this feature:
BLAST of TCONS_00070842-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
SERA1.128e-14753.55D-3-phosphoglycerate dehydrogenase OS=Homo sapiens... [more]
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