TCONS_00069681-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00069681-protein
Unique NameTCONS_00069681-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1669

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00069681-protein ID=TCONS_00069681-protein|Name=TCONS_00069681-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1669bp
MTTSPVDLISFDEFKPKVPPKSKQRTFSPPPFPPAVKREPDIRRVILSEL
EYYRPSSAQSNNNYASNLAFQDFTEGANNTNLNGGVNNNALENDSRCVSN
PDTLINNETESTQNFTENNNTDGPPLPPKKYGRSRANALERQVSLTRGEK
PKRDDELSPDVLSKSMPDTLYLFDPFLSESFIDEPTIVRGSQISDGGRTV
RSKTMVDDKNVVPTFDLLQFDIDIDETKDETSVESEVKLKSPTYRLSERR
KVKTLSPEDLQRFERSSSEKNQSNINKETKTKTLPARPPRPKNRFSCPPN
VIAGIGENSHKNGSDQKDSSTAEQSNNKNDIYFKTALFQRTEERNEEAVA
FSNAIAKLRKFYKHEDKSTNIGCIAPSKIANKALLDSTVEFTIYFDPDPK
PKTMTCKLSLTPTEVIHKFFTECYNGGKSFELDIIAEQYVLKFVGATTCL
SEQCPLCDYVTIQESIKYGYRIELVLVRTGFVNLDFKRDAEDDTEDCHST
YFKYYFEEKQTSSLSISEQGLSVLLETYDSEAARLMQDVSESHKVTYHPQ
RIIQVVKAITKSLAQVELLTVQEGVNMLLSLKKFTAHSKSFSAQRTDGRK
EVVEFMNPIHFDHQKFHSALQTLTQGVHSLIQLYCKFFNTDFKIQDFGSN
NIKIDQNDIFERIDPRTIDDRFTVRIGSIHRIPHSWKTTYTEFEIEASLY
YGGNLTATPKRTAKARVCVGFFEHIRFHELLEFDVSVRNIPRESKVTFKL
IGLSPPKKGGDGRTTLGWVSSNVYDHQGFLMSGSRLFGLLSEVHFNPVAT
CATGYIQKPETVILKTDFQVYHTEVLFPQPVLITQTSINGNPSTLSEAEM
TYVTKILRKDSRVLTQEERYVIWKSRYGLCHLPYALKHVLASCPSWDSIN
VTEVHTILSMWEALSPNEAIEFLQADFPDKTVRETAVLWLSSITDYDLVD
YLPELVQAIKYEAYHDSALAQFVIKRSLSSPSVAHFLFWHLKYYTGDLQF
SQRFQIVLSGLLSACGRRMRAQLQQQDNLMVELAQVSLKVKACKEPTRQL
LLVKELHKVNESNVEFPVRSPIDPSLKLGEILPESSSYFSSHTVPLKICM
RNVDRRGRDINFIFKIGDDLRKDLVTLLMFRVMNKLWLNEGLDLKMMLYN
VLPTGPLSGLIEIIPNAATFREIHIQHGLTGSFKDDSLILWLQRFNTTEQ
DYHRAIDNFTYSAAGYCVATYLLGIGDRHNDNIMLTKNGHLFHIDFSKFM
GDVQKFGAISRDRVPFVLTPDMAYVINNGITPTQNFQKFIEYCCQAFNII
RRNKHVILNLLGLMVYSGIPYLSEKEDLLFVRKNLQLDLTDEEATMYFTR
LIESSLSSRSTQLNFFIHNIAHMKNTSEATLGSAKSSPLFSFSNKTHTQA
KDGVINSARIVDFQKRYLPEKHYVFVINVTRKGVKEPKFVFRRFEDFQEL
HAKLSYKFNPFTGTIMPELPARIVLGRSQIREVAHRRRYELDNYLVALSK
LEDVWSSDILYTFLHSYIKDTEEARRFAEYVELLADGPKTRIGGKIKVSI
GYKNKALHVLVMHCSGLVPDRVQGLADSFVKVRIIPDPLHHYKRKTRICR
KTLHPTFNETLIFEASWEMLRKRVLQITVWDSNHLMDKEFLGGVNCYLST
FDVKKTQNAWFPLTDIQIS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_043387XLOC_043387Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00069681TCONS_00069681Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002420PI3K_C2_dom
IPR001683Phox
IPR000008C2_dom
IPR001263PInositide-3_kin_accessory_dom
IPR000403PI3/4_kinase_cat_dom
IPR000341PI3K_Ras-bd_dom
IPR018936PI3/4_kinase_CS
IPR016024ARM-type_fold
IPR029071Ubiquitin-rel_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0035091phosphatidylinositol binding
GO:0016301kinase activity
GO:0005488binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
molecular_function GO:0005488 binding
molecular_function GO:0016301 kinase activity
molecular_function GO:0035091 phosphatidylinositol binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002420Phosphatidylinositol 3-kinase, C2 domainSMARTSM00142pi3k_hr3_6coord: 660..769
e-value: 5.5E-7
score: 39.2
IPR002420Phosphatidylinositol 3-kinase, C2 domainPFAMPF00792PI3K_C2coord: 691..794
e-value: 6.4E-13
score: 48.8
IPR002420Phosphatidylinositol 3-kinase, C2 domainPROSITEPS51547PI3K_C2coord: 668..828
score: 30.028
IPR001683Phox homologous domainSMARTSM00312PX_2coord: 1403..1517
e-value: 1.3E-19
score: 81.2
IPR001683Phox homologous domainPFAMPF00787PXcoord: 1405..1516
e-value: 1.4E-18
score: 66.8
IPR001683Phox homologous domainGENE3D3.30.1520.10coord: 1401..1523
e-value: 6.2E-20
score: 70.8
IPR001683Phox homologous domainPROSITEPS50195PXcoord: 1403..1521
score: 16.442
IPR001683Phox homologous domainSUPERFAMILY64268PX domaincoord: 1402..1517
IPR000008C2 domainSMARTSM00239C2_3ccoord: 1556..1660
e-value: 3.4E-15
score: 66.5
IPR000008C2 domainPFAMPF00168C2coord: 1557..1663
e-value: 3.6E-16
score: 59.2
IPR000008C2 domainGENE3D2.60.40.150coord: 668..826
e-value: 2.6E-24
score: 85.0
IPR000008C2 domainGENE3D2.60.40.150coord: 1538..1668
e-value: 1.7E-26
score: 92.1
IPR000008C2 domainPROSITEPS50004C2coord: 1557..1645
score: 14.112
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 1543..1665
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 666..791
IPR001263Phosphoinositide 3-kinase, accessory (PIK) domainSMARTSM00145pi3k_hr2_4coord: 837..1024
e-value: 2.1E-49
score: 180.1
IPR001263Phosphoinositide 3-kinase, accessory (PIK) domainPFAMPF00613PI3Kacoord: 846..1021
e-value: 2.8E-40
score: 137.6
IPR001263Phosphoinositide 3-kinase, accessory (PIK) domainPROSITEPS51545PIK_HELICALcoord: 839..1014
score: 24.661
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainSMARTSM00146pi3k_hr1_6coord: 1111..1373
e-value: 2.8E-107
score: 372.4
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainPFAMPF00454PI3_PI4_kinasecoord: 1110..1320
e-value: 1.3E-48
score: 166.0
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainGENE3D1.10.1070.11coord: 1166..1360
e-value: 3.6E-56
score: 189.3
IPR000403Phosphatidylinositol 3-/4-kinase, catalytic domainPROSITEPS50290PI3_4_KINASE_3coord: 1110..1374
score: 67.257
NoneNo IPR availableGENE3D3.30.1010.10coord: 1017..1163
e-value: 2.2E-33
score: 114.9
NoneNo IPR availableGENE3D3.10.20.90coord: 331..489
e-value: 2.5E-13
score: 49.6
NoneNo IPR availableGENE3D1.25.40.70coord: 827..1016
e-value: 2.0E-47
score: 160.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..39
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 93..161
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 250..326
NoneNo IPR availableCDDcd04012C2A_PI3K_class_IIcoord: 663..828
e-value: 3.76139E-44
score: 159.061
IPR000341Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domainPFAMPF00794PI3K_rbdcoord: 391..478
e-value: 5.3E-9
score: 36.1
IPR000341Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domainPROSITEPS51546PI3K_RBDcoord: 386..478
score: 19.759
IPR018936Phosphatidylinositol 3/4-kinase, conserved sitePROSITEPS00916PI3_4_KINASE_2coord: 1212..1232
IPR016024Armadillo-type foldSUPERFAMILY48371ARM repeatcoord: 837..1016
IPR029071Ubiquitin-related domainSUPERFAMILY54236Ubiquitin-likecoord: 335..487
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 1049..1369

Blast
BLAST of TCONS_00069681-protein vs. Swiss-Prot (Human)
Match: P3C2A (Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha OS=Homo sapiens GN=PIK3C2A PE=1 SV=2)

HSP 1 Score: 821.231 bits (2120), Expect = 0.000e+0
Identity = 484/1359 (35.61%), Postives = 755/1359 (55.56%), Query Frame = 0
Query:  326 NNKNDIYFKTALFQRTEERNEEAVAFSNAIAKLRKFYKHEDKSTNIGCIAPSKIANKALL--DSTVEFTIYFDPDPKPKTMTCKLSLTPTEVIHKFFTECYNGGKSFELDIIAEQYVLKFVGATTCLSEQCPLCDYVTIQESIKYGYRIELVLVRTGFVNLDFKRDAEDDTEDCHSTYFKYYFEEKQTSSLSISEQGLSVLLETYDSEAARLMQDVSESHKVTYHPQRIIQVVKAITKSLAQVELLTVQEGVNMLLSL----KKFTAHSKSFSAQRTDGRKEVVEFMNPIHFDHQKFHSALQTLTQGVHSLIQLYCKFFNTDFKIQDFGSNNIKIDQNDIFERIDPRTIDDRFTVRIGSIHRIPHSWKTTYTEFEIEASLYYGGNLTATPKRTAKARVCVGFFEHIRFHELLEFDVSVRNIPRESKVTFKLIGL-------SP-PKKGGDGRTTLGWVSSNVYDHQGFLMSGSRLFGLLSEVHFNPVATCAT--GYIQKPETVILKTDFQVYHTEVLFPQPVLITQTSINGNPSTLSEAEMTYVTKILRKDSRV-LTQEERYVIWKSRYGLCHLPYALKHVLASCPSWDSINVTEVHTILSMWEALSPNEAIEFLQADFPDKTVRETAVLWLSSITDYDLVDYLPELVQAIKYEAYHDSALAQFVIKRSLSSPSVAHFLFWHLKYYTGDLQFSQRFQIVLSGLLSACGRRMRAQLQQQDNLMVELAQVSLKVKACKEPTRQLLLVKELHKVNESNVEFPVRSPIDPSLKLGEILPESSSYFSSHTVPLKICMRNVDRRGRDINFIFKIGDDLRKDLVTLLMFRVMNKLWLNEGLDLKMMLYNVLPTGPLSGLIEIIPNAATFREIHIQHGLTGSFKDDSLILWLQRFNTTEQDYHRAIDNFTYSAAGYCVATYLLGIGDRHNDNIMLTKNGHLFHIDFSKFMGDVQKFGAISRDRVPFVLTPDMAYVINNGITPTQNFQKFIEYCCQAFNIIRRNKHVILNLLGLMVYSGIPYLSEKEDLLFVRKNLQLDLTDEEATMYFTRLIESSLSSRSTQLNFFIHNIAHMKNTSEATLGSAKSSPLFSFSNKTHTQAKDGVINSARIVDFQKRYLPEKHYVFVINVTRKGVKEPKFVFRRFEDFQELHAKLSYKFNPFTGTIMPELPARIVLGRSQIREVAHRRRYELDNYLVALSKLE-DVWSSDILYTFLHSYIKDTEEARRFAEYVELLADGPK-TRIGGKIKVSIGYKNKALHVLVMHCSGLVPDRVQGLADSFVKVRIIPDPLHHYKRKTRICRKTLHPTFNETLIFEA-SWEMLRKRVLQITVWDSNHLMDKEFLGGVNCYLSTFDVKKTQNAWFPLT 1664
            N  + +   ++L Q  E +NEE  AF  +I KL+  + + +  TN G +     A + +   +++V+ +I  +    P T TC +S T   +I +    C+      ++D+ +  YVLK  G    L     L  +  IQ   K+   I L L+    +  +  R AEDD         K+ ++ ++    +++   +  LL++Y ++    +Q +   H+      ++I+ V+ I  +L  VE L + E V  L       +  TA   S        R      +NP          ++  LT  ++ L++L+    N+     D   ++  + +          T  ++    I + H I  +W + Y ++ +  SL + G     P ++ K      FF  I++ EL+ F + +  +P ES +   L G+       SP   K   G   LG VS  ++D + FL  G++L  L +  H N V    T  GY+   E ++L+ DF     ++++  P +        N  TL       +  IL KDS + L++E++  +W+ RY     P  L  +LAS P+W  +N+ + +++L  W AL P  A+E L + F D+ VR  AV W+ +I+D +L D LP+ VQA+KYE Y +S+L QF++ R+L +  +AH L+W LK    D+QFS R++ VL  LLS  G+R+R +L +Q  L+  L  V+ KV+      RQ++L + + +V     +   R P+ PSL   E+  +S S+FSS+ VPLK+ M N D  G +IN +FK+G+DLR+D++ L M ++M+K+WL EGLDL+M+++  L TG   G++E++P + T R+I +++G+TGSFKD  L  WL+++N +E++Y +A +NF YS AG CVATY+LGI DRHNDNIML   GH+FHIDF KF+G  Q FG+  RDR PFVLT DMAYVIN G  PT  FQ F++ CCQA+N+IR+  ++ LNLL LM+ SG+P L+  +DL +VR  LQ   TD EAT++FTRLIESSL S +T+ NFFIHN+A ++ +   +       P+ SFS KT++  +DG I    +  + K+Y P+KHY++V+ + R+G  EP FVFR F++FQELH KLS  F  +    +P  P R+VLGR+ I++VA +R+ EL++YL +L     DV   D++ TF H  ++D E+A   A   +  +  P   +IGG +K+SI Y+N  L ++VMH   LV +      + +VK  ++PD     KRKT+I RKT +PTFNE L++   S E LR+R LQ++V  +  L +  FLGGV   L  F++ K    W+ LT
Sbjct:  359 NGTSSLPTGSSLLQEVEVQNEEMAAFCRSITKLKTKFPYTNHRTNPGYLLSPVTAQRNICGENASVKVSIDIEGFQLPVTFTCDVSSTVEIIIMQAL--CWVHDDLNQVDVGS--YVLKVCGQEEVLQNNHCLGSHEHIQNCRKWDTEIRLQLLTFSAMCQNLARTAEDDETPVDLN--KHLYQIEKPCKEAMTRHPVEELLDSYHNQVELALQ-IENQHRAV---DQVIKAVRKICSALDGVETLAITESVKKLKRAVNLPRSKTADVTSLFGGEDTSRSSTRGSLNP----ENPVQVSINQLTAAIYDLLRLHA---NSGRSPTDCAQSSKSVKE--------AWTTTEQLQFTIFAAHGISSNWVSNYEKYYLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLFGILNQSSGSSPDSNKQRKGPEALGKVSLPLFDFKRFLTCGTKLLYLWTSSHTNSVPGTVTKKGYVM--ERIVLQVDFPSPAFDIIYTTPQVDRSIIQQHNLETLENDIKGKLLDILHKDSSLGLSKEDKAFLWEKRYYCFKHPNCLPKILASAPNWKWVNLAKTYSLLHQWPALYPLIALELLDSKFADQEVRSLAVTWIEAISDDELTDLLPQFVQALKYEIYLNSSLVQFLLSRALGNIQIAHNLYWLLKDALHDVQFSTRYEHVLGALLSVGGKRLREELLKQTKLVQLLGGVAEKVRQASGSARQVVLQRSMERVQSFFQKNKCRLPLKPSLVAKELNIKSCSFFSSNAVPLKVTMVNADPMGEEINVMFKVGEDLRQDMLALQMIKIMDKIWLKEGLDLRMVIFKCLSTGRDRGMVELVPASDTLRKIQVEYGVTGSFKDKPLAEWLRKYNPSEEEYEKASENFIYSCAGCCVATYVLGICDRHNDNIMLRSTGHMFHIDFGKFLGHAQMFGSFKRDRAPFVLTSDMAYVINGGEKPTIRFQLFVDLCCQAYNLIRKQTNLFLNLLSLMIPSGLPELTSIQDLKYVRDALQPQTTDAEATIFFTRLIESSLGSIATKFNFFIHNLAQLRFSGLPS----NDEPILSFSPKTYSFRQDGRIKEVSVFTYHKKYNPDKHYIYVVRILREGQIEPSFVFRTFDEFQELHNKLSIIFPLWK---LPGFPNRMVLGRTHIKDVAAKRKIELNSYLQSLMNASTDVAECDLVCTFFHPLLRD-EKAEGIARSADAGSFSPTPGQIGGAVKLSISYRNGTLFIMVMHIKDLVTEDGAD-PNPYVKTYLLPDNHKTSKRKTKISRKTRNPTFNEMLVYSGYSKETLRQRELQLSVLSAESLRENFFLGGVTLPLKDFNLSKETVKWYQLT 1681          
The following BLAST results are available for this feature:
BLAST of TCONS_00069681-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
P3C2A0.000e+035.61Phosphatidylinositol 4-phosphate 3-kinase C2 domai... [more]
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