TCONS_00067381-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00067381-protein
Unique Name	TCONS_00067381-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1001

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00067381-protein ID=TCONS_00067381-protein|Name=TCONS_00067381-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1001bp
LENTQIKMSNHSMNAGGLKEAKEYMMDKEIPQLFESMMTALMYKKPEDHI
EFLETCLNKAKEDPKIRWHSFIQPLPPIPKATEKIRTEAESPQPFAEDVL
ASPKAVSPVQNAPSDIVQKKTEASLLAEQVFNKHMQEIDALDNDDEKPWY
ADYTEKYIDTSAIQEKPIVFVLGGPGSGKGTQCAKIVEKYGFLHLSAGDL
LRAEVKKGSEIGAKIDQAIKEGQLVPQDVTICLLKEAMVAKADSKGFLID
GFPREIKQGKQFERQVASAKLMLNYECPDEVLTERLIERGKHSGRVDDNI
ESIKKRLVLFHEKTSPVVQHYSEIVSSIQANRSIDEVFEDTCKALEQSIN
SQPSTTDTSLDLAKPIVFILGAKSSGREKQCELLSHRYSLHHVSLDTILK
EDSEKFQDLMISYADNIPMGVALEAINKRIHNNKDNNGFIIDGFPRTLEE
AVCFEMEICPASFVVYFECPDDVLLRRQLGENAESEEEEAAKKNLESFHS
RMTPILLKYPDKLKIINSARSEDIIFKETCDFVDFLIAGQKSQVINEEQI
SPEQQKDIESAVQDIVNEIAPQQSSNDEPQVKSEGKPQVEGEEDHMEVQE
EPAGESGNKKLIYQEMLKNKKVIFVAGSPGTGKSTQCQKIAESFGYAHIS
KDLVLREIEAGTERGLKIVEFLKNKESVPDKLAFDILGEAMLEMDGCHGY
LMEGYPANVQQISVFEDEFKLADMVLHLTCPEIVASERFLSRGQPGDTHE
NYQERLDLYKEQTLPMLDLKVDLVKEIIVSGNPEEIFEEISKHFTEENSQ
TKPAEETKQEVMAGDLSNKNIVFVLGGPGSGKGTQCAKIVEKYGFCHLST
GDLLRAEVSSGSARAEEMKEIMAKGELIPLETILALLKEAMLKNSDCKGF
ILDGYPRDVPQGEKFEESVGKCKFILYFHCTNECMTERLLGRAKTSGRVD
DNIDTIKLRLKTFENQTLPILDKYSDRIKKIDAMRGVDDIFADVCKELDT
L

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_042095	XLOC_042095	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00067381	TCONS_00067381	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000850	Adenylat/UMP-CMP_kin
IPR006266	UMP_CMP_kinase
IPR033690	Adenylat_kinase_CS
IPR027417	P-loop_NTPase
IPR003117	cAMP_dep_PK_reg_su_I/II_a/b

Vocabulary: **Biological Process**
Term	Definition
GO:0006139	nucleobase-containing compound metabolic process
GO:0006221	pyrimidine nucleotide biosynthetic process
GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process

Vocabulary: **Molecular Function**
Term	Definition
GO:0019205	nucleobase-containing compound kinase activity
GO:0005524	ATP binding
GO:0004127	cytidylate kinase activity
GO:0009041	uridylate kinase activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process
biological_process	GO:0006139	nucleobase-containing compound metabolic process
biological_process	GO:0006221	pyrimidine nucleotide biosynthetic process
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0004127	cytidylate kinase activity
molecular_function	GO:0019205	nucleobase-containing compound kinase activity
molecular_function	GO:0009041	uridylate kinase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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POSITION

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 476..496
None	No IPR available	PFAM	PF00406	ADK	coord: 824..977 e-value: 7.7E-48 score: 162.3 coord: 171..323 e-value: 9.8E-50 score: 168.5 coord: 369..510 e-value: 4.3E-18 score: 65.8 coord: 625..768 e-value: 5.3E-26 score: 91.4
None	No IPR available	GENE3D	3.40.50.300		coord: 616..799 e-value: 6.4E-34 score: 117.0 coord: 816..1000 e-value: 1.2E-42 score: 145.5
None	No IPR available	GENE3D	1.20.890.10		coord: 18..62 e-value: 9.2E-12 score: 44.1
None	No IPR available	GENE3D	3.40.50.300		coord: 160..350 e-value: 2.8E-43 score: 147.5 coord: 361..538 e-value: 6.8E-23 score: 81.0
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 570..605
IPR000850	Adenylate kinase/UMP-CMP kinase	PRINTS	PR00094	ADENYLTKNASE	coord: 247..263 score: 48.85 coord: 198..212 score: 54.01 coord: 170..183 score: 70.58 coord: 295..310 score: 49.36 coord: 312..326 score: 26.44
IPR000850	Adenylate kinase/UMP-CMP kinase	HAMAP	MF_00235	Adenylate_kinase_Adk	coord: 167..346 score: 38.681
IPR000850	Adenylate kinase/UMP-CMP kinase	HAMAP	MF_00235	Adenylate_kinase_Adk	coord: 820..999 score: 38.597
IPR000850	Adenylate kinase/UMP-CMP kinase	HAMAP	MF_00235	Adenylate_kinase_Adk	coord: 621..795 score: 20.912
IPR000850	Adenylate kinase/UMP-CMP kinase	CDD	cd01428	ADK	coord: 168..337 e-value: 9.96547E-61 score: 204.778
IPR000850	Adenylate kinase/UMP-CMP kinase	CDD	cd01428	ADK	coord: 622..786 e-value: 3.06748E-30 score: 118.493
IPR000850	Adenylate kinase/UMP-CMP kinase	CDD	cd01428	ADK	coord: 821..990 e-value: 6.35077E-60 score: 202.467
IPR000850	Adenylate kinase/UMP-CMP kinase	CDD	cd01428	ADK	coord: 366..480 e-value: 7.02573E-21 score: 91.1442
IPR006266	UMP-CMP kinase	TIGRFAM	TIGR01359	TIGR01359	coord: 168..344 e-value: 1.2E-63 score: 212.4
IPR033690	Adenylate kinase, conserved site	PROSITE	PS00113	ADENYLATE_KINASE	coord: 247..258
IPR033690	Adenylate kinase, conserved site	PROSITE	PS00113	ADENYLATE_KINASE	coord: 900..911
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 621..793
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 818..999
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 166..348
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	52540	P-loop containing nucleoside triphosphate hydrolases	coord: 365..533
IPR003117	cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain	SUPERFAMILY	47391	Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit	coord: 18..61

Blast

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BLAST of TCONS_00067381-protein vs. Swiss-Prot (Human)
Match: KAD5 (Adenylate kinase isoenzyme 5 OS=Homo sapiens GN=AK5 PE=1 SV=2)

HSP 1 Score: 249.98 bits (637), Expect = 2.559e-72
Identity = 166/583 (28.47%), Postives = 290/583 (49.74%), Query Frame = 0

Query:   20 EAKEYMMDKEIPQLFESMMTALMYKKPEDHIEFLETCLNKAKE---DPKIRWHSFI----QPLPPIPKATEKIRTEAESPQPFAEDVLASPKAVSPVQNAPSDIVQKKTEASLLAEQVFNKHMQEIDALDNDDEKPWYADYTEKYIDTSAIQEKP-IVFVLGGPGSGKGTQCAKIVEKYGFLHLSAGDLLRAEVKKGS--EIGAKIDQAIKEGQLVPQDVTICLLKEAMVAKADSKGFLIDGFPREIKQGKQFERQVASAKLMLNYECPDEVLTERLIERGKHSGRVDDNIESIKKRLVLFHEKTSPVVQHYSE--IVSSIQANRSIDEVFEDTCKALEQSI--NSQPSTTDTSLDLAK----------------------------------------PIVFILGAKSSGREKQCELLSHRYSLHHVSLDTILKED-------SEKFQDLMISYADNIPMGVALEAINK-RIHNNKDNNGFIIDGFPRTLEEAVCFEMEICPASFVVYFECPDDVLLRRQLGENAES----EEEEAAKKNLESFHSRMTPILLKYPDKLKI--INSARSEDIIFKETCDFVD 534
            +AKEY+  +EIPQLFES++  LM  KPED +E+LE+CL K KE     K++W +F+    + LPP+           +S + F  +V+             S+   ++ +      Q          ++++D +    A+  E+Y      + +P I+ V+GGPGSGKGTQ  KI E+YGF ++S G+LLR ++   S     + I + I  G+L PQ+ TI  +K+ ++   D +G +IDGFPR++ Q   FE Q+ +  L++   C ++ L ERL++R +  GR DDN+++ ++RL+ F +  +P+V+++ E  ++ +  A+R  DEVF D   A++  +  N + +   + LD +                                          I+FI+G   SG+  QCE L  +Y   H+S   +L+E+       S+  +D+M    D +P G+ LE + +  + +  D  GF+IDG+PR +++   F   I     V+  +C  D +  R L  +  S    +  +   K LE+++    P++  Y  K ++  IN+  + + +F + C  +D
Sbjct:    5 DAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPL--------NGGQSRRSFLRNVMPEN----------SNFPYRRYDRLPPIHQF---------SIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIM-ERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAID 559

HSP 2 Score: 234.958 bits (598), Expect = 6.445e-67
Identity = 142/429 (33.10%), Postives = 229/429 (53.38%), Query Frame = 0

Query:  621 KVIFVAGSPGTGKSTQCQKIAESFGYAHISKDLVLREIEAGTERGLK---IVEFLKNKESVPDKLAFDILGEAMLEMDGCHGYLMEGYPANVQQISVFEDEFKLADMVLHLTCPEIVASERFLSR----GQPGDTHENYQERLDLYKEQTLPMLDL--KVDLVKEIIVSGNPEEIFEEIS----------KHFTEENSQTKPA-----------------------EETKQEVMAG---DLSNKNIVFVLGGPGSGKGTQCAKIVEKYGFCHLSTGDLLRAEVSSGSARAEEMKEIMAKGELIPLETILALLKEAMLKN-SDCKGFILDGYPRDVPQGEKFEESVGKCKFILYFHCTNECMTERLLGRAKTSGRVDDNIDTIKLRLKTFENQTLPILDKYSDR--IKKIDAMRGVDDIFADVCKELDTL 1001
            K+I V G PG+GK TQ  KIAE +G+ +IS   +LR+    T    K   I + +   E  P +     + + ++++    G +++G+P +V Q   FED+    D+V+ L C      ER L R    G+P D  +  Q RL  +K+   P++    +  L+       + +E+F +IS          K     +S   P+                           ++ M G   DL    I+F++GGPGSGKGTQC K+VEKYGF HLSTG+LLR E++S S R++ +++IM +G+L+P   +L LLKEAM+ +  D +GF++DGYPR+V QGE+F   +G  + ++   C+ + MT RLL R+++S  VDD   TI  RL+ +   ++P++  Y  +  + KI+A    +D+F  +C  +D++
Sbjct:  133 KIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSI 561

HSP 3 Score: 147.132 bits (370), Expect = 6.249e-37
Identity = 110/448 (24.55%), Postives = 208/448 (46.43%), Query Frame = 0

Query:  366 IVFILGAKSSGREKQCELLSHRYSLHHVSLDTILKE-----DSEKFQDLM---ISYADNIPMGVALEAINKRIHNNKDNNGFIIDGFPRTLEEAVCFEMEICPASFVVYFECPD----DVLLRRQLGENAESEEEEAAKKNLESFHSRMTPILLKYPDK--LKIINSARSEDIIFKETCDFVDFLIAGQKSQVINEEQISPEQQKDIESAVQDIVNEIAPQQSSNDEPQVKSEGKPQVEGEEDHMEVQEEPAGESGNKKLIYQEMLKNKKVIFVAGSPGTGKSTQCQKIAESFGYAHISKDLVLR-EIEAGTERGLKIVEFLKNKESVPDKLAFDILGEAMLEMDG-CHGYLMEGYPANVQQISVFEDEFKLADMVLHLTCPEIVASERFLSRGQPG----DTHENYQERLDLYKEQTLPML---DLKVDLVKEIIVSGNPEEIFEEI 790
            I+ ++G   SG+  Q   ++ RY   ++S+  +L++      S +   L+   I+  +  P    +  I +++    D  G +IDGFPR + +A+ FE +IC    VV+  C +    + LL+R   +    +  +A ++ L +F     P++  + +K  +   ++ R ED +F +    VD  +   K        + P    D      +I++  +  +   D+ Q+   G+  + G                     + E L+  K+IF+ G PG+GK TQC+K+ E +G+ H+S   +LR E+ + +ER   I + ++  + VP  +  ++L EAM+   G   G+L++GYP  V+Q   F        +V+ + C     + R L R +      DT +   +RL+ Y   ++P++   + K  L K I   G PE++F ++
Sbjct:  134 IILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILD----TGEIIDTGSDYEDQGDD-QLNVFGEDTMGG---------------------FMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHK-INAEGTPEDVFLQL 554

The following BLAST results are available for this feature:

BLAST of TCONS_00067381-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00067381-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
KAD5	2.559e-72	28.47	Adenylate kinase isoenzyme 5 OS=Homo sapiens GN=AK...	[more]

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TCONS_00067381-protein (polypeptide) - C. hemisphaerica

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