TCONS_00067381-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00067381-protein
Unique NameTCONS_00067381-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1001

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00067381-protein ID=TCONS_00067381-protein|Name=TCONS_00067381-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1001bp
LENTQIKMSNHSMNAGGLKEAKEYMMDKEIPQLFESMMTALMYKKPEDHI
EFLETCLNKAKEDPKIRWHSFIQPLPPIPKATEKIRTEAESPQPFAEDVL
ASPKAVSPVQNAPSDIVQKKTEASLLAEQVFNKHMQEIDALDNDDEKPWY
ADYTEKYIDTSAIQEKPIVFVLGGPGSGKGTQCAKIVEKYGFLHLSAGDL
LRAEVKKGSEIGAKIDQAIKEGQLVPQDVTICLLKEAMVAKADSKGFLID
GFPREIKQGKQFERQVASAKLMLNYECPDEVLTERLIERGKHSGRVDDNI
ESIKKRLVLFHEKTSPVVQHYSEIVSSIQANRSIDEVFEDTCKALEQSIN
SQPSTTDTSLDLAKPIVFILGAKSSGREKQCELLSHRYSLHHVSLDTILK
EDSEKFQDLMISYADNIPMGVALEAINKRIHNNKDNNGFIIDGFPRTLEE
AVCFEMEICPASFVVYFECPDDVLLRRQLGENAESEEEEAAKKNLESFHS
RMTPILLKYPDKLKIINSARSEDIIFKETCDFVDFLIAGQKSQVINEEQI
SPEQQKDIESAVQDIVNEIAPQQSSNDEPQVKSEGKPQVEGEEDHMEVQE
EPAGESGNKKLIYQEMLKNKKVIFVAGSPGTGKSTQCQKIAESFGYAHIS
KDLVLREIEAGTERGLKIVEFLKNKESVPDKLAFDILGEAMLEMDGCHGY
LMEGYPANVQQISVFEDEFKLADMVLHLTCPEIVASERFLSRGQPGDTHE
NYQERLDLYKEQTLPMLDLKVDLVKEIIVSGNPEEIFEEISKHFTEENSQ
TKPAEETKQEVMAGDLSNKNIVFVLGGPGSGKGTQCAKIVEKYGFCHLST
GDLLRAEVSSGSARAEEMKEIMAKGELIPLETILALLKEAMLKNSDCKGF
ILDGYPRDVPQGEKFEESVGKCKFILYFHCTNECMTERLLGRAKTSGRVD
DNIDTIKLRLKTFENQTLPILDKYSDRIKKIDAMRGVDDIFADVCKELDT
L
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_042095XLOC_042095Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00067381TCONS_00067381Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000850Adenylat/UMP-CMP_kin
IPR006266UMP_CMP_kinase
IPR033690Adenylat_kinase_CS
IPR027417P-loop_NTPase
IPR003117cAMP_dep_PK_reg_su_I/II_a/b
Vocabulary: Biological Process
TermDefinition
GO:0006139nucleobase-containing compound metabolic process
GO:0006221pyrimidine nucleotide biosynthetic process
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process
Vocabulary: Molecular Function
TermDefinition
GO:0019205nucleobase-containing compound kinase activity
GO:0005524ATP binding
GO:0004127cytidylate kinase activity
GO:0009041uridylate kinase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
biological_process GO:0006139 nucleobase-containing compound metabolic process
biological_process GO:0006221 pyrimidine nucleotide biosynthetic process
molecular_function GO:0005524 ATP binding
molecular_function GO:0004127 cytidylate kinase activity
molecular_function GO:0019205 nucleobase-containing compound kinase activity
molecular_function GO:0009041 uridylate kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 476..496
NoneNo IPR availablePFAMPF00406ADKcoord: 824..977
e-value: 7.7E-48
score: 162.3
coord: 171..323
e-value: 9.8E-50
score: 168.5
coord: 369..510
e-value: 4.3E-18
score: 65.8
coord: 625..768
e-value: 5.3E-26
score: 91.4
NoneNo IPR availableGENE3D3.40.50.300coord: 616..799
e-value: 6.4E-34
score: 117.0
coord: 816..1000
e-value: 1.2E-42
score: 145.5
NoneNo IPR availableGENE3D1.20.890.10coord: 18..62
e-value: 9.2E-12
score: 44.1
NoneNo IPR availableGENE3D3.40.50.300coord: 160..350
e-value: 2.8E-43
score: 147.5
coord: 361..538
e-value: 6.8E-23
score: 81.0
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 570..605
IPR000850Adenylate kinase/UMP-CMP kinasePRINTSPR00094ADENYLTKNASEcoord: 247..263
score: 48.85
coord: 198..212
score: 54.01
coord: 170..183
score: 70.58
coord: 295..310
score: 49.36
coord: 312..326
score: 26.44
IPR000850Adenylate kinase/UMP-CMP kinaseHAMAPMF_00235Adenylate_kinase_Adkcoord: 167..346
score: 38.681
IPR000850Adenylate kinase/UMP-CMP kinaseHAMAPMF_00235Adenylate_kinase_Adkcoord: 820..999
score: 38.597
IPR000850Adenylate kinase/UMP-CMP kinaseHAMAPMF_00235Adenylate_kinase_Adkcoord: 621..795
score: 20.912
IPR000850Adenylate kinase/UMP-CMP kinaseCDDcd01428ADKcoord: 168..337
e-value: 9.96547E-61
score: 204.778
IPR000850Adenylate kinase/UMP-CMP kinaseCDDcd01428ADKcoord: 622..786
e-value: 3.06748E-30
score: 118.493
IPR000850Adenylate kinase/UMP-CMP kinaseCDDcd01428ADKcoord: 821..990
e-value: 6.35077E-60
score: 202.467
IPR000850Adenylate kinase/UMP-CMP kinaseCDDcd01428ADKcoord: 366..480
e-value: 7.02573E-21
score: 91.1442
IPR006266UMP-CMP kinaseTIGRFAMTIGR01359TIGR01359coord: 168..344
e-value: 1.2E-63
score: 212.4
IPR033690Adenylate kinase, conserved sitePROSITEPS00113ADENYLATE_KINASEcoord: 247..258
IPR033690Adenylate kinase, conserved sitePROSITEPS00113ADENYLATE_KINASEcoord: 900..911
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 621..793
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 818..999
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 166..348
IPR027417P-loop containing nucleoside triphosphate hydrolaseSUPERFAMILY52540P-loop containing nucleoside triphosphate hydrolasescoord: 365..533
IPR003117cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domainSUPERFAMILY47391Dimerization-anchoring domain of cAMP-dependent PK regulatory subunitcoord: 18..61

Blast
BLAST of TCONS_00067381-protein vs. Swiss-Prot (Human)
Match: KAD5 (Adenylate kinase isoenzyme 5 OS=Homo sapiens GN=AK5 PE=1 SV=2)

HSP 1 Score: 249.98 bits (637), Expect = 2.559e-72
Identity = 166/583 (28.47%), Postives = 290/583 (49.74%), Query Frame = 0
Query:   20 EAKEYMMDKEIPQLFESMMTALMYKKPEDHIEFLETCLNKAKE---DPKIRWHSFI----QPLPPIPKATEKIRTEAESPQPFAEDVLASPKAVSPVQNAPSDIVQKKTEASLLAEQVFNKHMQEIDALDNDDEKPWYADYTEKYIDTSAIQEKP-IVFVLGGPGSGKGTQCAKIVEKYGFLHLSAGDLLRAEVKKGS--EIGAKIDQAIKEGQLVPQDVTICLLKEAMVAKADSKGFLIDGFPREIKQGKQFERQVASAKLMLNYECPDEVLTERLIERGKHSGRVDDNIESIKKRLVLFHEKTSPVVQHYSE--IVSSIQANRSIDEVFEDTCKALEQSI--NSQPSTTDTSLDLAK----------------------------------------PIVFILGAKSSGREKQCELLSHRYSLHHVSLDTILKED-------SEKFQDLMISYADNIPMGVALEAINK-RIHNNKDNNGFIIDGFPRTLEEAVCFEMEICPASFVVYFECPDDVLLRRQLGENAES----EEEEAAKKNLESFHSRMTPILLKYPDKLKI--INSARSEDIIFKETCDFVD 534
            +AKEY+  +EIPQLFES++  LM  KPED +E+LE+CL K KE     K++W +F+    + LPP+           +S + F  +V+             S+   ++ +      Q          ++++D +    A+  E+Y      + +P I+ V+GGPGSGKGTQ  KI E+YGF ++S G+LLR ++   S     + I + I  G+L PQ+ TI  +K+ ++   D +G +IDGFPR++ Q   FE Q+ +  L++   C ++ L ERL++R +  GR DDN+++ ++RL+ F +  +P+V+++ E  ++ +  A+R  DEVF D   A++  +  N + +   + LD +                                          I+FI+G   SG+  QCE L  +Y   H+S   +L+E+       S+  +D+M    D +P G+ LE + +  + +  D  GF+IDG+PR +++   F   I     V+  +C  D +  R L  +  S    +  +   K LE+++    P++  Y  K ++  IN+  + + +F + C  +D
Sbjct:    5 DAKEYLARREIPQLFESLLNGLMCSKPEDPVEYLESCLQKVKELGGCDKVKWDTFVSQEKKTLPPL--------NGGQSRRSFLRNVMPEN----------SNFPYRRYDRLPPIHQF---------SIESDTDLSETAELIEEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIM-ERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAID 559          

HSP 2 Score: 234.958 bits (598), Expect = 6.445e-67
Identity = 142/429 (33.10%), Postives = 229/429 (53.38%), Query Frame = 0
Query:  621 KVIFVAGSPGTGKSTQCQKIAESFGYAHISKDLVLREIEAGTERGLK---IVEFLKNKESVPDKLAFDILGEAMLEMDGCHGYLMEGYPANVQQISVFEDEFKLADMVLHLTCPEIVASERFLSR----GQPGDTHENYQERLDLYKEQTLPMLDL--KVDLVKEIIVSGNPEEIFEEIS----------KHFTEENSQTKPA-----------------------EETKQEVMAG---DLSNKNIVFVLGGPGSGKGTQCAKIVEKYGFCHLSTGDLLRAEVSSGSARAEEMKEIMAKGELIPLETILALLKEAMLKN-SDCKGFILDGYPRDVPQGEKFEESVGKCKFILYFHCTNECMTERLLGRAKTSGRVDDNIDTIKLRLKTFENQTLPILDKYSDR--IKKIDAMRGVDDIFADVCKELDTL 1001
            K+I V G PG+GK TQ  KIAE +G+ +IS   +LR+    T    K   I + +   E  P +     + + ++++    G +++G+P +V Q   FED+    D+V+ L C      ER L R    G+P D  +  Q RL  +K+   P++    +  L+       + +E+F +IS          K     +S   P+                           ++ M G   DL    I+F++GGPGSGKGTQC K+VEKYGF HLSTG+LLR E++S S R++ +++IM +G+L+P   +L LLKEAM+ +  D +GF++DGYPR+V QGE+F   +G  + ++   C+ + MT RLL R+++S  VDD   TI  RL+ +   ++P++  Y  +  + KI+A    +D+F  +C  +D++
Sbjct:  133 KIILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSI 561          

HSP 3 Score: 147.132 bits (370), Expect = 6.249e-37
Identity = 110/448 (24.55%), Postives = 208/448 (46.43%), Query Frame = 0
Query:  366 IVFILGAKSSGREKQCELLSHRYSLHHVSLDTILKE-----DSEKFQDLM---ISYADNIPMGVALEAINKRIHNNKDNNGFIIDGFPRTLEEAVCFEMEICPASFVVYFECPD----DVLLRRQLGENAESEEEEAAKKNLESFHSRMTPILLKYPDK--LKIINSARSEDIIFKETCDFVDFLIAGQKSQVINEEQISPEQQKDIESAVQDIVNEIAPQQSSNDEPQVKSEGKPQVEGEEDHMEVQEEPAGESGNKKLIYQEMLKNKKVIFVAGSPGTGKSTQCQKIAESFGYAHISKDLVLR-EIEAGTERGLKIVEFLKNKESVPDKLAFDILGEAMLEMDG-CHGYLMEGYPANVQQISVFEDEFKLADMVLHLTCPEIVASERFLSRGQPG----DTHENYQERLDLYKEQTLPML---DLKVDLVKEIIVSGNPEEIFEEI 790
            I+ ++G   SG+  Q   ++ RY   ++S+  +L++      S +   L+   I+  +  P    +  I +++    D  G +IDGFPR + +A+ FE +IC    VV+  C +    + LL+R   +    +  +A ++ L +F     P++  + +K  +   ++ R ED +F +    VD  +   K        + P    D      +I++  +  +   D+ Q+   G+  + G                     + E L+  K+IF+ G PG+GK TQC+K+ E +G+ H+S   +LR E+ + +ER   I + ++  + VP  +  ++L EAM+   G   G+L++GYP  V+Q   F        +V+ + C     + R L R +      DT +   +RL+ Y   ++P++   + K  L K I   G PE++F ++
Sbjct:  134 IILVIGGPGSGKGTQSLKIAERYGFQYISVGELLRKKIHSTSSNRKWSLIAKIITTGELAPQETTITEIKQKLMQIPDEEGIVIDGFPRDVAQALSFEDQICTPDLVVFLACANQRLKERLLKRAEQQGRPDDNVKATQRRLMNFKQNAAPLVKYFQEKGLIMTFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILD----TGEIIDTGSDYEDQGDD-QLNVFGEDTMGG---------------------FMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHK-INAEGTPEDVFLQL 554          
The following BLAST results are available for this feature:
BLAST of TCONS_00067381-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
KAD52.559e-7228.47Adenylate kinase isoenzyme 5 OS=Homo sapiens GN=AK... [more]
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