TCONS_00066946-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00066946-protein
Unique Name	TCONS_00066946-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	728

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00066946-protein ID=TCONS_00066946-protein|Name=TCONS_00066946-protein|organism=Clytia hemisphaerica|type=polypeptide|length=728bp
QTTRKKIKLKVNMKLFAALVVLCLAGDVYSKINLKSIISVNNIKEYKKIL
KRNKNVLTLYAKEDKSALNYLRWMEDVAKDIKGKGTIVYINCGESKDAKK
LCKKYSVTPKPKLLKHYKDGEFNKDYDRKDTAKSLLNFMLDPTGDAPWEE
DPAAKNVVQVSSEKELVKLRRKEKGPMLIMFYAPWCGYCKRLKPDYAAAA
TELKGKAVLVGMDVDKPDAFNVRYQFNITGFPTLIYFENGEQKYNYAGKM
DKEGLISWMQDPKPAEDKKEEEEESWSEQAPEILHLTDSTFDEGLKEHAS
IVVMFYAPWCGHCKSMKPEFVDAAKQMTEEETAGKLAAVDCTKETKVCKK
FDISGYPTVKYFENAEYKFKLNIRKKDEIVKFMKNPEEPPQPPPEDLPWS
EVSGPEILHLTDANFKDELKKKKHVLVMFYAPWCGHCKKAKPEIEKAAAT
FTEDRKVWFAGVDCTVDKKSCEQFGVSGYPTFRYFLYGKKDFKYEGGRNT
DAFIEFMKNPKEESAEPEMREPEWKDTPSGVVHLGENDFDDFIKSHPSML
VMFYAPWCGHCKQMKPAYTEAANELLGTDHAIAAVDCTKNRKLASKYSIS
GYPTLKYFKDGQPSDYDAGRDKDSIVSYLIQKTSGEPPKKKLTGWAAENN
FVNHLDSDNFDSHMQDNPSVLVMFYAPWCGHCKKMKPDYADASHVINHEK
RIPGSMAAVDCTANADICNRFEIRGYPT

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_041839	XLOC_041839	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00066946	TCONS_00066946	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR013766	Thioredoxin_domain
IPR017937	Thioredoxin_CS
IPR012336	Thioredoxin-like_fold

Vocabulary: **Biological Process**
Term	Definition
GO:0045454	cell redox homeostasis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0045454	cell redox homeostasis

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01

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POSITION

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IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	PRINTS	PR00421	THIOREDOXIN	coord: 598..609 score: 40.93 coord: 425..433 score: 63.02 coord: 557..566 score: 57.94
None	No IPR available	GENE3D	3.40.30.10		coord: 518..643 e-value: 9.2E-35 score: 119.4 coord: 644..728 e-value: 3.3E-21 score: 75.3 coord: 397..517 e-value: 1.2E-34 score: 119.0 coord: 273..396 e-value: 4.0E-28 score: 97.8
None	No IPR available	GENE3D	3.40.30.10		coord: 30..145 e-value: 1.3E-10 score: 41.0
None	No IPR available	GENE3D	3.40.30.10		coord: 146..272 e-value: 7.3E-29 score: 99.8
None	No IPR available	SFLD	SFLDG00345	PDI-like	coord: 171..261 e-value: 2.4E-22 score: 73.6 coord: 409..509 e-value: 1.6E-29 score: 96.7 coord: 652..728 e-value: 5.5E-23 score: 75.7 coord: 285..385 e-value: 1.3E-29 score: 97.0 coord: 531..632 e-value: 5.1E-29 score: 95.1
None	No IPR available	CDD	cd02961	PDI_a_family	coord: 532..629 e-value: 1.01698E-36 score: 132.734
None	No IPR available	CDD	cd02961	PDI_a_family	coord: 655..728 e-value: 5.0164E-28 score: 108.082
None	No IPR available	CDD	cd02997	PDI_a_PDIR	coord: 406..507 e-value: 8.00301E-45 score: 155.168
IPR013766	Thioredoxin domain	PFAM	PF00085	Thioredoxin	coord: 170..260 e-value: 2.1E-22 score: 78.9 coord: 652..728 e-value: 4.7E-19 score: 68.2 coord: 407..508 e-value: 2.8E-28 score: 97.8 coord: 531..629 e-value: 1.1E-27 score: 95.9 coord: 283..384 e-value: 9.1E-25 score: 86.5
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 287..385 score: 8.59
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 140..282 score: 14.759
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 386..512 score: 16.804
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 641..728 score: 10.556
IPR013766	Thioredoxin domain	PROSITE	PS51352	THIOREDOXIN_2	coord: 513..634 score: 13.759
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 671..689
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 178..196
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 302..320
IPR017937	Thioredoxin, conserved site	PROSITE	PS00194	THIOREDOXIN_1	coord: 550..568
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 646..728
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 521..633
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 34..144
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 276..388
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 400..510
IPR012336	Thioredoxin-like fold	SUPERFAMILY	52833	Thioredoxin-like	coord: 155..263

Blast

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BLAST of TCONS_00066946-protein vs. Swiss-Prot (Human)
Match: PDIA5 (Protein disulfide-isomerase A5 OS=Homo sapiens GN=PDIA5 PE=1 SV=1)

HSP 1 Score: 397.897 bits (1021), Expect = 5.765e-131
Identity = 220/511 (43.05%), Postives = 318/511 (62.23%), Query Frame = 0

Query:   15 LFAALVVLCLAGDVYSKINLKSIIS-VNNIKEYKKILKRNKNVLTLYAKEDKSALNYLRWMEDVAKDIKGKGTIVYINCGESKDAKKLCKKYSVTPKPK----LLKHYKDGEFNKDYDRKDTAKSLLNFMLDPTGDAPWEEDPAAKNVVQVSSEKELVKLRRKEKGPMLIMFYAPWCGYCKRLKPDYAAAATELKGKAVLVGMDVDKPDAFNVRYQFNITGFPTLIYFENGEQKYNYAG-KMDKEGLISWMQDPKPAEDKKEEEEESWSEQAPEILHLTDSTFDEGLKEHASIVVMFYAPWCGHCKSMKPEFVDAAKQM-TEEETAGKLAAVDCTKETKVCKKFDISGYPTVKYFENAEYKFKLNIRKKDEIVKFMKNPEEPPQPPPEDLPWSEVSGPEILHLTDANFKDELKKKKHVLVMFYAPWCGHCKKAKPEIEKAAATFTEDRKVWFAGVDCTVDKKS--CEQFGVSGYPTFRYFLYGKKDFKYEGGRNTDAFIEFMKNPKEESAE 516
            L A  VVL       S   + S+I  +++ K+ KK+L+   NVL LY+K + +A N+LR +  VA+ +KG+GTI +++CG++ +++KLCKK  V   PK     L HY+DG F+ +Y+R  T KS++ F+ DP G   WEEDP AK+VV + SEK+  +L +KE+ P+LIMFYAPWC  CKR+ P +  AAT+L+G AVL GM+V   +  N++ ++++ GFPT+ YFE G   + Y       E ++ W+++  P   + +  E  W+++   + HLTD  FD+ +KEH+S++VMF+APWCGHCK MKPEF  AA+ +  E +++G LAAVD T    + ++F IS +PT+KYF+N E      +R K + +++M+NPE PP P P      E     +LHL   NF++ LKKKKH LVMFYAPWC HCKK  P     A  F +DRK+  A VDC  DK    C+Q  V GYPTF Y+ YGK   KY+  R    F  +++  +E   E
Sbjct:   10 LLAIWVVL---PSWLSSAKVSSLIERISDPKDLKKLLRTRNNVLVLYSKSEVAAENHLRLLSTVAQAVKGQGTICWVDCGDA-ESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPPLWEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKN--PQPPQPQVPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGEKYAVPVLRTKKKFLEWMQNPEAPPPPEPT----WEEQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTELGFTNYIRALREGDHE 510

HSP 2 Score: 230.72 bits (587), Expect = 2.754e-67
Identity = 147/415 (35.42%), Postives = 219/415 (52.77%), Query Frame = 0

Query:  334 GKLAAVDC--TKETKVCKKFDISGYPTVKYFE---------NAEYKFKLNIRKKDEIVKFMKNPEEPPQPPPEDLPWSEVSGP-EILHL-TDANFKDELKKK-KHVLVMFYAPWCGHCKKAKPEIEKAAATFTEDRKVWFAGVDCTVDKKSCEQFGVSGYPTFRYFLYGKKDFKYEG-GRNTDAFIEFMKNPKEESAEPEMREPEWKDTPSGVVHLGENDFDDFIKSHPSMLVMFYAPWCGHCKQMKPAYTEAANELLG---TDHAIAAVDCTKNRKLASKYSISGYPTLKYFKDGQPSDYDAGRDKDSIVSYLIQKTSGEPPKKKLTGWAAENNFVNHLDSDNFDSHMQDNPSVLVMFYAPWCGHCKKMKPDYADASHVINHEKRIPGSMAAVDCT--ANADICNRFEIRGYPT 728
            G +  VDC   +  K+CKK  +   P  K  E         + EY   +  +    IV F+K+P+ PP        W E  G  +++HL ++ +F+  LKK+ K +L+MFYAPWC  CK+  P  +KAA        +    V  +  +   E++ V G+PT  YF  G+  F+Y+  G   +  +E++KNP+    +  + E  W D    V HL + DFD F+K H S+LVMF+APWCGHCK+MKP + +AA  L G   +   +AAVD T N+ LA ++ IS +PTLKYFK+G+       R K   + ++    +  PP+        +   V HL  DNF   ++     LVMFYAPWC HCKK+ P +   +     +++I  + AAVDC    N D+C +  ++GYPT
Sbjct:   78 GTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFK---SIVAFLKDPKGPPL-------WEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFENIKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQ--VPETPWADEGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGEKYAVPVLRTKKKFLEWMQNPEAPPPPEPTWE---EQQTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKI--ACAAVDCVKDKNQDLCQQEAVKGYPT 475

HSP 3 Score: 211.075 bits (536), Expect = 3.846e-60
Identity = 152/497 (30.58%), Postives = 252/497 (50.70%), Query Frame = 0

Query:  157 VVQVSSEKELVKLRRKEKGPMLIMFYAPWCGYCKRLKPDYAAAATELKGKAVLVGMDVDKPDAFNVRYQFNITGFPT-----LIYFENGEQKYNYAGKMDKEGLISWMQDPKPAEDKKEEEEESWSEQ--APEILHL-TDSTFDEGLK-EHASIVVMFYAPWCGHCKSMKPEFVDAAKQMTEEETAGKLAAVDCTKETKVCKKFDISGYPTVKYFENAEYKFKLNI--RKKDEIVKFMKNPEEPPQPPPEDLPWSEVSGPEILHLTDANFKDELKKKKHVLVMFYAPWCGHCKKAKPEIEKAAATF--TEDRKVWFAGVDCTVDKKSCEQFGVSGYPTFRYFLYGKKDFKYEGGRNTDAFIEFMKNPKEESAEPEMREPEWKDTPSGVVHLGENDFDDFIKSHPSMLVMFYAPWCGHCKQMKPAYTEAANELLGTDH-AIAAVDCTK--NRKLASKYSISGYPTLKYFKDGQPSD-YDAGRDKDSIVSYLIQKTSGE 636
            + ++S  K+L KL R  +  +L+++          L+   +  A  +KG+  +  +D    ++  +  +  +   P      L ++++G     Y   +  + ++++++DPK            W E   A +++HL ++  F   LK E   +++MFYAPWC  CK M P F  AA Q+        +       E  + +++ + G+PT+ YFE   + F+ +      ++IV+++KNP+ P    PE  PW++  G  + HLTD +F   +K+   VLVMF+APWCGHCKK KPE EKAA       D     A VD TV+K   E+F +S +PT +YF  G+K +     R    F+E+M+NP+         E +     + V+HL  ++F + +K     LVMFYAPWC HCK++ P +T  A+        A AAVDC K  N+ L  + ++ GYPT  Y+  G+ ++ YD+ R +    +Y+     G+
Sbjct:   30 IERISDPKDLKKLLRT-RNNVLVLYSKSEVAAENHLRL-LSTVAQAVKGQGTICWVDCGDAESRKLCKKMKVDLSPKDKKVELFHYQDGAFHTEYNRAVTFKSIVAFLKDPKGPP--------LWEEDPGAKDVVHLDSEKDFRRLLKKEEKPLLIMFYAPWCSMCKRMMPHFQKAATQLRGHAVLAGMNVYSSEFEN-IKEEYSVRGFPTICYFEKGRFLFQYDNYGSTAEDIVEWLKNPQPPQPQVPET-PWAD-EGGSVYHLTDEDFDQFVKEHSSVLVMFHAPWCGHCKKMKPEFEKAAEALHGEADSSGVLAAVDATVNKALAERFHISEFPTLKYFKNGEK-YAVPVLRTKKKFLEWMQNPEAPPPPEPTWEEQ----QTSVLHLVGDNFRETLKKKKHTLVMFYAPWCPHCKKVIPHFTATADAFKDDRKIACAAVDCVKDKNQDLCQQEAVKGYPTFHYYHYGKFAEKYDSDRTELGFTNYIRALREGD 508

The following BLAST results are available for this feature:

BLAST of TCONS_00066946-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00066946-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1

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Match Name	E-value	Identity	Description
PDIA5	5.765e-131	43.05	Protein disulfide-isomerase A5 OS=Homo sapiens GN=...	[more]

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TCONS_00066946-protein (polypeptide) - C. hemisphaerica

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