TCONS_00063807-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00063807-protein
Unique NameTCONS_00063807-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length494

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00063807-protein ID=TCONS_00063807-protein|Name=TCONS_00063807-protein|organism=Clytia hemisphaerica|type=polypeptide|length=494bp
QETEFKIQAENRWIGSLYTMTPGNSTTKREYRKLIGWLSDSIIKAKLDEM
KFFLGVPAGKNEKIQTPLEFFQYMEGEGQLGQNNFDTLIDIMETIGRIDL
VQRIKKFQEISKETEAPITVELAPQTFTSPPGNLSLNLQSLSPGHDDQSI
QSISPGASESIAEEMIRPELSEKVFTPPPFQQAEESCGSQNRQTFVLTSN
YENKSGGSMKQDHPKESKDILKRYKMDSNPRGIFLIISNSDFSFALEKNG
LTINDRDGTIKDVERLDKTFTGLQFDIKKYHDLDAESMEKCLEYFATLDH
TYYDCFACCIMTHGTESTLVGTDGDEIQLTNVLGKFESVKSLIGKPKLFF
FQACRGKPAKKPYFTKDSAPGGYGGASTWDDNMFGKRYTPPLGSDYFIGY
ATPPNHDAWLSKDGSWYITALCESLNKYSATDDIHHIATYTNDLVAQYSH
GAGIPQIPNPTYTLRKQLYFFPENIDTVVRTVAPKKKSKEPAES
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_040001XLOC_040001Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00063807TCONS_00063807Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR015917Pept_C14A
IPR001875DED_dom
IPR033139Caspase_cys_AS
IPR016129Caspase_his_AS
IPR001309Pept_C14_p20
IPR002138Pept_C14_p10
IPR011029DEATH-like_dom
IPR029030Caspase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0008234cysteine-type peptidase activity
GO:0005515protein binding
GO:0004197cysteine-type endopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0042981regulation of apoptotic process
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
biological_process GO:0042981 regulation of apoptotic process
molecular_function GO:0004197 cysteine-type endopeptidase activity
molecular_function GO:0008234 cysteine-type peptidase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015917Peptidase C14A, caspase catalytic domainPRINTSPR00376IL1BCENZYMEcoord: 306..314
score: 39.73
coord: 462..471
score: 43.64
coord: 407..418
score: 36.11
coord: 339..357
score: 60.61
coord: 230..243
score: 40.26
IPR015917Peptidase C14A, caspase catalytic domainSMARTSM00115caspase_2coord: 223..472
e-value: 5.0E-61
score: 218.7
IPR015917Peptidase C14A, caspase catalytic domainCDDcd00032CASccoord: 223..471
e-value: 9.32687E-71
score: 226.713
IPR001875Death effector domainSMARTSM00031ded_6coord: 29..106
e-value: 1.9E-5
score: 34.1
IPR001875Death effector domainPFAMPF01335DEDcoord: 31..108
e-value: 1.5E-15
score: 57.1
IPR001875Death effector domainPROSITEPS50168DEDcoord: 30..106
score: 14.421
NoneNo IPR availableGENE3D3.30.70.1470coord: 387..474
e-value: 8.8E-19
score: 66.8
NoneNo IPR availableGENE3D3.40.50.1460coord: 190..365
e-value: 2.8E-30
score: 104.9
NoneNo IPR availableGENE3D1.10.533.10coord: 26..115
e-value: 3.8E-15
score: 55.4
NoneNo IPR availablePFAMPF00656Peptidase_C14coord: 235..470
e-value: 4.2E-33
score: 115.2
NoneNo IPR availableCDDcd00045DEDcoord: 31..105
e-value: 1.72494E-14
score: 67.9976
IPR033139Peptidase family C14A, cysteine active sitePROSITEPS01122CASPASE_CYScoord: 345..356
IPR016129Peptidase family C14A, His active sitePROSITEPS01121CASPASE_HIScoord: 300..314
IPR001309Peptidase C14, p20 domainPROSITEPS50208CASPASE_P20coord: 230..358
score: 34.481
IPR002138Peptidase C14, caspase non-catalytic subunit p10PROSITEPS50207CASPASE_P10coord: 386..472
score: 20.182
IPR011029Death-like domainSUPERFAMILY47986DEATH domaincoord: 30..122
IPR029030Caspase-like domainSUPERFAMILY52129Caspase-likecoord: 219..472

Blast
[Close]
BLAST of TCONS_00063807-protein vs. Swiss-Prot (Human)
Match: CASP8 (Caspase-8 OS=Homo sapiens GN=CASP8 PE=1 SV=1)

HSP 1 Score: 159.458 bits (402), Expect = 2.367e-43
Identity = 140/466 (30.04%), Postives = 215/466 (46.14%), Query Frame = 0 
Query:   56 VPAGKNEKIQTPLEFFQYMEGEGQLGQNNFDTLIDIMETIGRIDLVQRI--KKFQEISKETEAP----------ITVELAPQTFTSPPGNLSLNLQ---SLSPGHDDQSIQSISPGASESIA---------------------------EEMIRPELSEKVFTPPPFQQAEESCGSQNRQTFVLTSNYENKSGGSMKQDHPKESKDILKRYKMDSNPRGIFLIISNSDFSFALEK--NGLTINDRDGTIKDVERLDKTFTGLQFDIKKYHDLDAESMEKCLEYFATLDHTYYDCFACCIMTHGTESTLVGTDGDEIQLTNVLGKFESVK--SLIGKPKLFFFQACRGKPAKK--PYFTKDSAPGGYGGASTWDDNMFGKRYTPPLGSDYFIGYATPPNHDAWLS-KDGSWYITALCESLNKYSAT-DDIHHIATYTNDLVAQYSHGAGI-PQIPNPTYTLRKQLYF 470
            +P  K E I+  L  FQ ++ +  L ++N   L +++  I R+DL+      + +E+ +E + P          +  +++ +   S   +    LQ   S     DD ++  I     + +                            EE  +   S    +P  F   EE CG       V+T      S    +QD   ES+ + K Y+M S PRG  LII+N +F+ A EK     +I DR+GT  D   L  TF  L F+IK + D   E + + L+ +  +DH+  DCF CCI++HG +  + GTDG E  +  +  +F  +K  SL GKPK+FF QAC+G   +K  P  T DS    Y      D +    RY P   +D+ +G AT  N  ++ +  +G+WYI +LC+SL +     DDI  I T  N  V+       +  Q+P PT+TLRK+L F
Sbjct:   30 IPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEEFSKERSSSLEGSPDEFSNGEELCG-------VMTI-----SDSPREQD--SESQTLDKVYQMKSKPRGYCLIINNHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQLMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQACQGDNYQKGIPVET-DSEEQPY---LEMDLSSPQTRYIPD-EADFLLGMATVNNCVSYRNPAEGTWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVF 476
The following BLAST results are available for this feature:
BLAST of TCONS_00063807-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
CASP82.367e-4330.04Caspase-8 OS=Homo sapiens GN=CASP8 PE=1 SV=1[more]
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